
Ergothioneine is a naturally occurring, sulfur-containing amino acid derivative and a powerful, “smart” antioxidant that is actively transported into cells via a specific transporter (OCTN1). Its key efficacy lies in its exceptional cellular protection against oxidative stress (ROS), its unique ability to mitigate UV and blue light damage, and its proven role in preserving DNA and mitochondrial health. It is a cutting-edge, high-stability active ingredient for premium anti-photoaging, DNA defense, and longevity formulations in both topical and ingestible forms.
| Plant Source | Mushrooms |
|---|---|
| Extract Purity | 98% or higher |
| Appearance | White to off-white powder |
| CAS Number | 497-30-1 |
| Molecular Formula | C9H15N3O2S |
| Molecular Weight | 227.3 g/mol |
| EINECS Number | 207-850-8 |
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while actively utilizing a dedicated cellular transporter (OCTN1) to accumulate inside mitochondria and neutralize reactive oxygen species (ROS) at the absolute source.
In the advanced landscape of dermatological anti-aging and cellular longevity, achieving profound mitochondrial protection without triggering surface irritation is the ultimate formulation challenge. Our premium, high-purity Ergothioneine is rigorously engineered to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By targeting the fundamental processes of cellular aging, it acts as a “Smart Antioxidant” that halts UV and blue-light-induced oxidative stress, safeguards cellular DNA, and deeply soothes the inflammatory cascade in hyper-reactive skin.
For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Ergothioneine powder dissolves flawlessly and directly into the aqueous phase, yielding a crystal-clear, completely water-white, and entirely odorless profile. It will never compromise the precise color, fragrance, or aesthetic of your final product. Exceptionally thermo-stable and resistant to oxidation, it survives high-heat manufacturing processes that destroy traditional Vitamin C, completely eliminating stability nightmares and manufacturing friction for your R&D teams.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market next-generation digital protection (anti-blue light) and profound cellular longevity. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing cellular defense that stops photoaging and chronic dullness at the mitochondrial level before it ever surfaces.
Appearance: Fine white powder (yields a clear, water-white aqueous solution)
Odor: Odorless (scent neutral)
Purity: ≥ 98.0% (Ergothioneine content)
Heavy Metals: < 10 ppm
Recommended Usage: 0.01% – 0.5% (Topical Skincare)
pH Range Stability: Exceptionally stable between 4.0 – 7.5
Processing Guidelines: Highly water-soluble. Dissolve completely in the aqueous phase. Exceptionally heat-stable, allowing for seamless integration at almost any stage of the formulation process.
Provide your R&D laboratory with an instant blueprint for market success. Our Ergothioneine acts as a supreme biological antioxidant, protecting and amplifying the restorative efficacy of companion actives:
Ergothioneine + Allantoin: The ultimate cellular regeneration matrix. Combines the targeted mitochondrial DNA protection of Ergothioneine with the water-soluble wound-healing properties of Allantoin to instantly clear oxidative micro-traumas and safely soothe post-procedure skin.
Ergothioneine + Panthenol: A comprehensive “SOS Barrier Rescue” and anti-inflammaging system. Panthenol floods the stratum corneum with deep, targeted hydration, creating a healthy, non-reactive environment that allows Ergothioneine to efficiently neutralize blue-light and UV-induced free radicals without triggering irritation.
Ergothioneine + Ceramide NP: The absolute cellular longevity and structural defense complex. While Ergothioneine buffers oxidative stress within the nucleus and cellular machinery from the inside out, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, youthful, and perfectly protected skin barrier.
Formulate with absolute regulatory confidence. Shaanxi Huatai Bio-Fine Chemicals Co. strictly adheres to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO
COSMOS
HALAL
IQNET
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, traditional antioxidant degradation, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing cellular longevity actives.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Clinical Efficacy Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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