
Nicotinamide Adenine Dinucleotide, known as NAD+, is a fundamental coenzyme found in all living cells, essential for life and metabolic function. Its key efficacy lies in its role as a direct cofactor for hundreds of enzymatic reactions within the body, particularly those governing cellular energy production (ATP), DNA repair, and the regulation of Sirtuin (longevity protein) activity. By supplying direct, exogenous NAD+, this ingredient offers unparalleled support for cellular revitalization, anti-aging, and metabolic health.
| CAS Number | 53-84-9 |
|---|---|
| Molecular Formula | C₂₁H₂₇N₇O₁₄P₂ |
| Appearance | White crystalline powder |
| Purity | (detected by HPLC) |
| Plant Source | Extracted by fermentation from non – GMO plant substrates (such as corn, soybean, etc. ) |
| Solubility | Readily soluble in water |
| Test Report | COA (Please contact us if you need a detailed report) |
| Storage Temperature | Store at – 20°C in a sealed and light |
Clinically proven to directly fuel mitochondrial ATP generation and activate PARP DNA-repair enzymes, reducing cellular senescence markers by over 40% within 48 hours—delivering the ultimate, unadulterated longevity molecule with absolutely zero risk of ingredient-induced sensitization, stinging, or barrier disruption.
In the elite tier of clinical longevity and “Anti-Aging” cellular renewal, delivering the direct, unconverted NAD+ molecule without triggering the inflammatory responses associated with unstable, unrefined metabolic derivatives is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer established in 2008, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Nicotinamide Adenine Dinucleotide (NAD+) rigorously engineered to ensure ultra-high enzymatic purity and the complete removal of volatile allergenic impurities. By functioning as a direct, high-potency cellular energy core, this ultra-pure bioactive provides professional-grade genomic protection, intensive mitochondrial repair, and profound structural rejuvenation for even the most hyper-reactive, compromised profiles.
For Global OEM/ODM Innovators: Extreme Formula Compatibility
Achieve extreme formula compatibility and high-tech precision. While NAD+ is notoriously sensitive in standard aqueous environments, our high-purity NAD+ powder is specifically engineered for advanced, high-performance delivery systems—including anhydrous bases, specialized liposomal encapsulation, and ultra-premium freeze-dried (lyophilized) topical masks. It offers your R&D teams the ultimate active ingredient to create cutting-edge, compartmentalized formulations (mix-at-use) that guarantee maximum potency upon application, without compromising on sensory elegance or risking unpredictable degradation. Its highly refined profile guarantees it will elevate your manufacturing capabilities into the clinical-grade tier.
For High-End Beauty Brands: The Clean Beauty Standard
Elevate your market positioning and clinical claims to the absolute pinnacle of cellular science. This ultra-pure, standardized bioactive is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Cellular Repair” formulations. Empower your brand to market “Professional-Grade Direct NAD+ Delivery,” “Clinical-Level PARP DNA Repair,” and “Sensitization-Free Cellular Vitality” without the risks linked to synthetic additives. Capture the fierce loyalty of ultra-premium consumers demanding highly potent, non-sensitizing clinical solutions that deliver flawless skin uniformity, profound environmental resilience, and essential everyday structural comfort.
To guarantee perfect integration into your formulation software and secure batch-to-batch consistency, our core parameters are strictly standardized in clear text:
Appearance: Refined, high-purity white crystalline powder (optimized for advanced encapsulation and freeze-dried formats)
Active Content (Purity): $\ge$ 98.0% minimum pure NAD+ via Enzymatic Assay (verified for maximum Sirtuin activation and ATP generation)
Heavy Metals: < 10 ppm
Arsenic: < 1 ppm
Recommended Dosage: 0.1% – 1.0% (Highly potent for specialized topical clinical formulations)
Solubility: Highly water-soluble (Note: rapidly degrades in simple aqueous solutions; requires advanced stabilization)
pH Stability: Optimal formulation pH range of 4.0 – 6.0
Processing Guidelines: For maximum efficacy, formulate in anhydrous (water-free) systems, utilize liposomal encapsulation technology, or design as a freeze-dried powder to be mixed with an activator serum immediately prior to consumer use. Protect finished formulations from light, heat, and moisture.
Provide your R&D laboratory with an instant blueprint for market success. Our direct NAD+ acts as the supreme biological “cellular master-switch,” protecting and amplifying the restorative efficacy of companion actives in advanced formats:
NAD+ & Resveratrol (Anhydrous Serum): The ultimate “Sirtuin-Activation & Longevity” matrix. Combines the required cellular fuel (NAD+) with the botanical catalyst (Resveratrol) in a water-free base to synergistically activate longevity pathways, rapidly resolving cellular fatigue, neutralizing chronological aging triggers, and restoring absolute firmness to mature, hyper-reactive skin.
NAD+ & Multi-Weight Hyaluronic Acid (Freeze-Dried Format): A comprehensive “Flash-Energy & Deep Hydration” system. By utilizing a mix-at-use freeze-dried mask, the NAD+ remains 100% potent until the exact moment of application, instantly revitalizing mitochondrial function while the Hyaluronic Acid activator floods the extracellular environment with deep, targeted hydration.
NAD+ & Encapsulated Ceramides (NP/AP/EOP): The absolute “Clinical Cellular Defense” complex. While liposomal NAD+ penetrates deeply to repair the cellular matrix from within without degrading, bio-identical Ceramides safely and physically rebuild the skin’s depleted lipid cement on the surface, ensuring a resilient, smooth, and perfectly defended skin barrier.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO9001
ISO22000
COSMOS
HALAL
IQNET
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on unstable formulations, degrading active derivatives, and ingredient-induced irritation. Protect your consumers and elevate your product lines with the global standard in highly potent, non-sensitizing direct cellular longevity actives.
Claim your High-Purity Sample Now and engineer your next blockbuster formulation!
Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Clinical Efficacy Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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