
Phosphatidylserine (PS) is a naturally occurring phospholipid found in cell membranes, crucial for cell structure and signaling. In skincare, it is utilized for its exceptional ability to support and repair the skin barrier, function as a precursor and modulator for lipid production (including Ceramides), and provide potent anti-inflammatory and soothing effects by managing cell-to-cell communication. It is a premium, biomimetic active ingredient for high-performance barrier restoration, sensitive skin care, and advanced repair formulations.
| INCI Name | Phosphatidylserine |
|---|---|
| CAS No. | 51446-62-9 |
| Origin | Extracted from soy or sunflower |
| Appearance | Light yellow to brownish powder |
| Odor | Mild plant scent |
| Purity | ≥ 20% (customizable) |
| Recommended Usage | 0.1% – 3% |
| pH Stability | 4.0–7.5 |
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while delivering superior biomimetic barrier repair by stimulating endogenous ceramide synthesis—effectively reconstructing the lipid matrix of hyper-reactive, compromised skin with zero risk of irritation.
In the advanced landscape of clinical barrier recovery and “Skin-Identical” anti-aging, delivering profound cellular membrane stabilization without triggering surface inflammatory flare-ups is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer established in 2008, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Phosphatidylserine extract rigorously engineered to completely remove residual protein impurities and volatile allergens. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By functioning as a high-potency, biomimetic lipid modulator, this ultra-pure bioactive provides professional-grade cellular membrane fluidity, intensive anti-inflammatory suppression, and profound structural rejuvenation for even the most hyper-reactive, compromised skin.
For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and versatility. Our high-purity Phosphatidylserine is engineered for superior lipophilic integration, ensuring seamless dispersion into your high-performance delivery systems, including barrier-repair creams, post-procedural balms, and intensive night-treatment emulsions. It offers exceptional stability within your emulsion systems, ensuring your R&D teams can deliver consistent, reliable performance across complex multi-active formulations without compromising viscosity or sensory elegance. Its refined, odorless, and color-neutral profile guarantees it will never interfere with your brand’s signature product aesthetics.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, standardized bioactive is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Professional-Grade Cellular Architecture Repair,” “Ceramide-Synthesis Activation,” and “Biomimetic Barrier Resilience” without the risks linked to synthetic additives. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver flawless skin uniformity, profound environmental resilience, and essential everyday structural comfort.
Appearance: Refined, high-purity lipid concentrate (optimized for aesthetic integration)
Active Content: Standardized to ≥ 95.0% pure Phosphatidylserine (HPLC verified for maximum membrane-stabilization and barrier-repair power)
Heavy Metals: < 10 ppm
Arsenic: < 1 ppm
Recommended Dosage: 0.1% – 1.0% (Highly potent for daily structural repair and barrier fortification)
pH Stability: Highly stable across the optimal pH range of 5.0 – 7.5
Processing Guidelines: Highly lipophilic. Incorporate directly into the oil phase of emulsions at temperatures below 40°C to preserve structural integrity. Compatible with most cosmetic systems, including Ceramides, Niacinamide, and hydrating complexes.
Provide your R&D laboratory with an instant blueprint for market success. Our Phosphatidylserine acts as a supreme biological “cellular architect,” protecting and amplifying the restorative efficacy of companion actives:
Phosphatidylserine + Ceramides (NP/AP/EOP): The ultimate “Deep Barrier Construction” matrix. Combines the metabolic signaling of Phosphatidylserine to stimulate endogenous ceramide production with the external delivery of identical lipids to rapidly resolve barrier gaps, neutralize micro-inflammation, and restore equilibrium to hyper-reactive skin.
Phosphatidylserine + Panthenol: A comprehensive “SOS Barrier Rescue” and conditioning system. Panthenol floods the stratum corneum with deep, targeted hydration, creating a healthy, non-reactive environment that allows Phosphatidylserine to effectively modulate membrane stability without triggering tightness or reactivity.
Phosphatidylserine + Niacinamide: The absolute structural longevity and “Clean Beauty Defense” complex. While Phosphatidylserine works fundamentally from within to stabilize cellular membranes and suppress inflammatory cytokines, Niacinamide safely and physically optimizes barrier function on the surface, ensuring a resilient, smooth, and perfectly defended skin architecture.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO9001
ISO22000
COSMOS
HALAL
IQNET
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, volatile botanical extracts, and ingredient-induced irritation. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing clinical barrier-repair actives.
Claim your High-Purity Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Clinical Efficacy Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




Room 1901, Building 2, Wanda Plaza, Beilin District, Xi'an, Shaanxi.
Email: [email protected]
Phone: +86 17868678161
Copyright © 2026. Shaanxi Huatai Bio-Fine Chemical Co., Ltd. All Rights reserved.