
The Essential Barrier Fortifier for Cellular Growth and Intensive Hydration
Panthenol, the stable precursor to Vitamin B5 (Pantothenic Acid), is a foundational cosmetic grade active celebrated for its multi-functional efficacy. It acts as both a powerful humectant and a biological catalyst, promoting epithelial cell proliferation and accelerating the skin’s natural repair process to create a visibly stronger and more hydrated barrier.
| CAS No. | 81-13-0 (D-Panthenol) / 16485-10-2 (DL-Panthenol) |
|---|---|
| Source | High-Purity Cosmetic Synthesis |
| Appearance Color | Colorless to Pale Yellow Viscous Liquid (D) / White Powder (DL) |
| Key Parameter | Purity ≥ 98.0% / High Hygroscopicity |
| Solubility | Highly Water-Soluble / Soluble in Alcohol |
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, significantly decrease Transepidermal Water Loss (TEWL) by 35%, and visibly accelerate the repair of damaged skin within just 7 days of use.
In the advanced dermatological skincare sector, providing deep, restorative hydration without triggering further irritation is the ultimate formulation challenge. Our premium Cosmetic-Grade Panthenol (Provitamin B5) is rigorously engineered to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization on hyper-reactive skin. By rapidly converting into Pantothenic Acid deep within the dermis, it fuels cellular energy, stimulates fibroblast proliferation, and instantly soothes the inflammatory cascade to fundamentally reinforce the skin’s long-term resilience against environmental stressors.

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Panthenol dissolves flawlessly into the aqueous phase, yielding a crystal-clear, water-white, and entirely odorless profile. It ensures zero sticky residue and guarantees it will never compromise the precise color, fragrance, or aesthetic of your final emulsion systems. Exceptionally stable across a broad pH and temperature range, it completely eliminates manufacturing friction for your R&D teams.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Vitamin B5 Hero” products alongside medical-aesthetic recovery lines. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver immediate relief from dryness and absolute structural defense without daily irritation.
Appearance: Crystal-clear, water-white profile (ensures zero formula discoloration)
Odor: Odorless (scent neutral)
Purity: ≥ 95.0% (Available in highly active D-Panthenol & DL-Panthenol forms)
Specific Rotation (D-form): +29.0° to +31.5°
Heavy Metals: < 10 ppm
Recommended Usage: 1.0% – 5.0% (Standard Skincare) / Up to 10.0% (Intensive Therapeutic Repair)
pH Range Stability: Exceptionally stable between 4.0 – 7.5
Processing Guidelines: Water-soluble. Can be easily added to the aqueous phase. For emulsions, integration below 40°C is recommended to maintain maximum efficacy.
Provide your R&D laboratory with an instant blueprint for market success. Our Panthenol acts as a supreme biological repair agent, protecting and amplifying the restorative efficacy of companion actives for total barrier health:
Panthenol + Allantoin: The ultimate “Soothing Duo” and cellular clearing matrix. Combines the deep-penetrating fibroblast stimulation of Panthenol with the water-soluble wound-healing properties of Allantoin to rapidly clear micro-traumas and instantly soothe inflamed, hypersensitive, or post-procedure skin.
Panthenol + Ceramide NP: The absolute “Barrier Rescue” and structural longevity complex. While Panthenol floods the lower layers of the epidermis with deep, targeted hydration and fuels cellular energy from within, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, balanced, and perfectly protected environment.
Formulate with absolute regulatory confidence. Shaanxi Huatai Bio-Fine Chemicals Co. strictly adheres to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments and are completely free from sensitizing impurities. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO
COSMOS
HALAL
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, sticky residues, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing barrier repair actives.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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