What Is Totarol? Chemical Structure, Natural Sources and Scientific Background
Totarol is a naturally occurring phenolic diterpene. It has been...
The Essential Barrier Fortifier for Cellular Growth and Intensive Hydration
Panthenol, the stable precursor to Vitamin B5 (Pantothenic Acid), is a foundational cosmetic grade active celebrated for its multi-functional efficacy. It acts as both a powerful humectant and a biological catalyst, promoting epithelial cell proliferation and accelerating the skin’s natural repair process to create a visibly stronger and more hydrated barrier.
| CAS No. | 81-13-0 (D-Panthenol) / 16485-10-2 (DL-Panthenol) |
|---|---|
| Source | High-Purity Cosmetic Synthesis |
| Appearance Color | Colorless to Pale Yellow Viscous Liquid (D) / White Powder (DL) |
| Key Parameter | Purity ≥ 98.0% / High Hygroscopicity |
| Solubility | Highly Water-Soluble / Soluble in Alcohol |
Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.
Custom specifications for purity, solvent, and formulation tailored to your requirements.
Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.
ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, significantly decrease Transepidermal Water Loss (TEWL) by 35%, and visibly accelerate the repair of damaged skin within just 7 days of use.
In the advanced dermatological skincare sector, providing deep, restorative hydration without triggering further irritation is the ultimate formulation challenge. Our premium Cosmetic-Grade Panthenol (Provitamin B5) is rigorously engineered to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization on hyper-reactive skin. By rapidly converting into Pantothenic Acid deep within the dermis, it fuels cellular energy, stimulates fibroblast proliferation, and instantly soothes the inflammatory cascade to fundamentally reinforce the skin’s long-term resilience against environmental stressors.

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Panthenol dissolves flawlessly into the aqueous phase, yielding a crystal-clear, water-white, and entirely odorless profile. It ensures zero sticky residue and guarantees it will never compromise the precise color, fragrance, or aesthetic of your final emulsion systems. Exceptionally stable across a broad pH and temperature range, it completely eliminates manufacturing friction for your R&D teams.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Vitamin B5 Hero” products alongside medical-aesthetic recovery lines. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver immediate relief from dryness and absolute structural defense without daily irritation.
Appearance: Crystal-clear, water-white profile (ensures zero formula discoloration)
Odor: Odorless (scent neutral)
Purity: ≥ 95.0% (Available in highly active D-Panthenol & DL-Panthenol forms)
Specific Rotation (D-form): +29.0° to +31.5°
Heavy Metals: < 10 ppm
Recommended Usage: 1.0% – 5.0% (Standard Skincare) / Up to 10.0% (Intensive Therapeutic Repair)
pH Range Stability: Exceptionally stable between 4.0 – 7.5
Processing Guidelines: Water-soluble. Can be easily added to the aqueous phase. For emulsions, integration below 40°C is recommended to maintain maximum efficacy.
Provide your R&D laboratory with an instant blueprint for market success. Our Panthenol acts as a supreme biological repair agent, protecting and amplifying the restorative efficacy of companion actives for total barrier health:
Panthenol + Allantoin: The ultimate “Soothing Duo” and cellular clearing matrix. Combines the deep-penetrating fibroblast stimulation of Panthenol with the water-soluble wound-healing properties of Allantoin to rapidly clear micro-traumas and instantly soothe inflamed, hypersensitive, or post-procedure skin.
Panthenol + Ceramide NP: The absolute “Barrier Rescue” and structural longevity complex. While Panthenol floods the lower layers of the epidermis with deep, targeted hydration and fuels cellular energy from within, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, balanced, and perfectly protected environment.
Formulate with absolute regulatory confidence. Shaanxi Huatai Bio-Fine Chemicals Co. strictly adheres to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments and are completely free from sensitizing impurities. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO
COSMOS
HALAL
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
| Question | Answer |
| What is the difference between D-Panthenol and DL-Panthenol, and which do you supply? | D-Panthenol is the biologically active form of Vitamin B5, providing superior skin and hair repair benefits, while DL-Panthenol is a synthetic mixture with lower efficacy. As a professional cosmetic ingredient manufacturer, Shaanxi Huatai strictly supplies high-purity D-Panthenol for premium skincare and haircare formulations. |
| Do you supply Panthenol in liquid or powder form, and what are the concentrations? | Shaanxi Huatai offers both forms to perfectly match your manufacturing needs. We supply pure D-Panthenol powder (99 percent purity) for high-concentration formulas, and D-Panthenol 75W (a 75 percent aqueous solution) which is highly convenient for direct liquid formulations and cold processing. |
| Is your D-Panthenol water-soluble, and how should it be added to cosmetic formulas? | Yes, the D-Panthenol manufactured by Shaanxi Huatai is exceptionally water-soluble. It can be easily incorporated into the water phase of your formulations. It is highly stable at a pH range of 4.0 to 7.5 and is ideal for both hot and cold-process manufacturing. |
| What is the recommended usage rate of D-Panthenol for skin barrier repair and hair care? | For general moisturizing and daily soothing, a usage rate of 1 to 5 percent is recommended. For intensive skin barrier repair and professional haircare treatments, concentrations can safely reach 10 percent. The technical team at Shaanxi Huatai can provide customized dosage guidelines for your specific project. |
| Why is D-Panthenol considered a core ingredient for sensitive skin and baby care products? | D-Panthenol deeply hydrates, significantly reduces transepidermal water loss, and accelerates epidermal repair. Because it is highly biocompatible and non-irritating, global formulators trust Shaanxi Huatai to supply pure D-Panthenol for sensitive skin serums, eczema relief creams, and gentle baby care lines. |
| Do you provide a Certificate of Analysis (COA) and MSDS for wholesale bulk orders? | Absolutely. Strict quality control is fundamental to our factory operations. Shaanxi Huatai provides comprehensive, batch-specific documentation for every wholesale shipment, including the COA, MSDS, and purity testing reports, ensuring seamless compliance for your QA team. |
| What is the Minimum Order Quantity (MOQ) for bulk Panthenol, and can I test a sample? | To support both independent formulation labs and large-scale manufacturing facilities, Shaanxi Huatai offers a highly flexible MOQ starting at just 1kg. We also gladly provide 10g to 50g free R&D testing samples so you can evaluate formulation compatibility before committing to a bulk order. |
| Why should I source bulk D-Panthenol directly from your factory in China? | By sourcing directly from a primary manufacturer like Shaanxi Huatai, you secure factory-direct competitive pricing without middleman markups. We guarantee consistent batch-to-batch quality, direct access to our technical support team, and rapid global shipping to keep your production lines running smoothly. |
Stop compromising on formula stability, sticky residues, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing barrier repair actives.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).
Totarol is a naturally occurring phenolic diterpene. It has been...
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Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.
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Email: [email protected]
Phone: +86 17868678161
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