Active skincare ingredients
  • Guaiazulene
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Products
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Factory
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Exhibition
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd.

Guaiazulene

Guaiazulene is a naturally occurring bicyclic sesquiterpene derived from chamomile oil, characterized by its striking deep blue color and superior anti-inflammatory and soothing properties. It actively inhibits the release of inflammatory mediators and histamine, making it highly effective for calming sensitive skin, reducing redness, and accelerating the repair of damaged or irritated skin barrier.

INCI Name

Guaiazulene

CAS No.

489-84-9

Purity

≥98%

Appearance

Blue Liquid

Core Function

Anti-inflammatory, Soothing, Anti-allergic, Redness Reduction, Skin Repair

The Ultimate 100% Farnesol-Free Guaiazulene: Custom-Engineered for Extremely Sensitive Skin & Zero Sensitization

Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while immediately inhibiting histamine release and rapidly mitigating severe redness, swelling, and inflammation for profound post-procedure tissue repair.

In the advanced landscape of dermatological repair and reactive skin management, instantly mitigating the inflammatory cascade without triggering secondary sensitization is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer established in 2008, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Guaiazulene rigorously engineered to completely remove residual impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By effectively inhibiting the formation of inflammatory mediators regulated by the COX-2 pathway, this ultra-pure active stabilizes mast cells and provides professional-grade, fast-acting soothing for even the most hyper-reactive and compromised skin.

Unlocking Unmatched Business Value

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Guaiazulene dissolves flawlessly into the oil phase or suitable solvents, engineered to yield a highly refined, water-white, and entirely odorless profile in specific concentrations. It ensures zero unintended formula discoloration and guarantees it will never compromise the precise color, fragrance, transparency, or aesthetic of your final calming serums or post-procedure masks. Exceptionally potent at trace inclusion rates, it completely eliminates the manufacturing friction and aesthetic degradation typically associated with standard therapeutic extracts for your R&D teams.

For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, fast-acting active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Post-Procedure Care,” “Rapid Anti-Redness,” and powerful inflammatory cascade inhibition. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver flawless skin calming and intense tissue repair without irritation.

Product Overview & Core Specifications

  • Appearance: High-Purity Liquid (yields a refined, water-white, odorless profile in finished formulations)

  • Odor: Odorless (scent neutral for absolute formulation control)

  • Purity: ≥ 98.0% (Maximum histamine inhibition and cell repair support)

  • Heavy Metals: < 10 ppm

  • Recommended Usage: 0.01% – 0.1% (Highly effective at trace inclusion rates)

  • pH & Stability Requirements: Avoid formulating with strong acids or strong alkalis. Protect the final product from direct light and air to maintain stability.

  • Processing Guidelines: Oil-soluble. Must be dissolved in a suitable oil phase, ethanol, or propylene glycol before being added to the final formula. Add during the cooling phase (below 40°C) to ensure active properties are fully preserved.

Ready-to-Use Solutions: The Golden Synergies

Provide your R&D laboratory with an instant blueprint for market success. Our Guaiazulene acts as a supreme biological soothing engine, protecting and amplifying the restorative efficacy of companion actives:

  • Guaiazulene + Allantoin: The ultimate post-procedure and cellular clearing matrix. Combines the targeted COX-2 pathway inhibition and anti-allergic action of Guaiazulene with the water-soluble wound-healing properties of Allantoin to rapidly clear micro-traumas, halt histamine release, and instantly soothe severely irritated, hyper-reactive skin.

  • Guaiazulene + Panthenol: A comprehensive “SOS Barrier Rescue” and anti-redness system. Panthenol floods the stratum corneum with deep, targeted hydration, creating a healthy, non-reactive environment that allows Guaiazulene to effectively calm rosacea-like symptoms and speed up recovery without triggering tightness or reactivity.

  • Guaiazulene + Ceramide NP: The absolute structural longevity and “Emergency Repair” complex. While Guaiazulene works fundamentally from within to reduce swelling and promote tissue regeneration, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, calm, and perfectly protected skin barrier against further external trauma.

Uncompromising Quality Assurance

Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:

  • ISO9001

  • ISO22000

  • COSMOS

  • HALAL

Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.

Upgrade Your Next Bestseller Today

Stop compromising on formula stability, harsh chemical soothers, and ingredient-induced irritation. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing anti-inflammatory actives.

Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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