
The Potent Natural Alternative for Intensive Anti-Itch and Sensitivity Relief
Dihydroavenanthramide D is a nature-inspired, high-performance cosmetic grade active synthesized to mimic the powerful soothing alkaloids found in oats. It is widely recognized as a “Steroid-Free” solution for rapidly suppressing itchiness, redness, and allergic responses, providing a safe and effective treatment for compromised and hyper-reactive skin barriers.
| CAS No. | 697235-49-7 |
|---|---|
| Source | High-Purity Biomimetic Synthesis |
| Appearance Color | Colorless to Light Yellow Transparent Liquid |
| Key Parameter | Inhibition of Histamine Release / High Purity |
| Solubility | Water-Soluble (Propylene Glycol base) |
Clinically proven to be 30x more potent than conventional oat extracts in inhibiting histamine release, reducing UV-induced erythema by 50% within 24 hours, and effectively decreasing skin sensitivity markers by 40% within 48 hours.
In the advanced dermatological skincare sector, instantly switching off neurogenic inflammation without relying on hormones or steroids is the ultimate formulation challenge. Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Cosmetic-Grade Dihydroavenanthramide D rigorously engineered to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By actively blocking histamine release from mast cells and suppressing pro-inflammatory cytokines (IL-8 and TNF-α), it delivers medical-grade soothing results, instantly calming the sensations of burning, stinging, and tightness in the most delicate and hyper-reactive skin types.
For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Dihydroavenanthramide D dissolves flawlessly into the aqueous phase, yielding a crystal-clear, water-white, and entirely odorless profile. It guarantees zero formula discoloration and ensures it will never compromise the precise color, fragrance, or aesthetic of your final serums or infant care lotions. Exceptionally stable across a wide pH range (3.5 – 7.0) and highly resistant to thermal or oxidative degradation, it completely eliminates manufacturing friction for your R&D teams.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market steroid-free, non-hormonal “Anti-Itch” miracles and infant-safe recovery lines. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver immediate comfort and long-term safety for chronic skin sensitivity and eczema-prone profiles.
Appearance: Crystal-clear, water-white liquid (ensures zero formula discoloration)
Odor: Odorless (scent neutral)
Active Content: Standardized 5.0% Solution (Synthetic derivative of Avenanthramides)
Purity Profile: 100% Steroid-Free and Farnesol-Free
Heavy Metals: < 10 ppm
Recommended Usage: 1.0% – 5.0% (Standard Skincare) / Up to 10.0% (Intensive “SOS” Treatments)
pH Range Stability: Exceptionally stable between 3.5 – 7.0
Processing Guidelines: Water-soluble. Readily incorporated into the aqueous phase or at the end of the formulation process below 45°C.
Provide your R&D laboratory with an instant blueprint for market success. Our Dihydroavenanthramide D acts as a supreme biological neuro-calmer, protecting and amplifying the restorative efficacy of companion actives:
Dihydroavenanthramide D + Allantoin: The ultimate “Itch Relief” and cellular clearing matrix. Combines the rapid histamine inhibition of Dihydroavenanthramide D with the water-soluble wound-healing properties of Allantoin to instantly clear micro-traumas and safely soothe hyper-reactive, stinging, or post-procedure skin.
Dihydroavenanthramide D + Panthenol: A comprehensive “SOS Barrier Rescue” and deep-soothing system. Panthenol floods the stratum corneum with targeted hydration and cellular energy, while Dihydroavenanthramide D suppresses pro-inflammatory cytokines. This creates a perfectly balanced, non-reactive environment that rapidly halts inflammatory triggers without any steroidal side effects.
Dihydroavenanthramide D + Ceramide NP: The absolute structural longevity and anti-allergy complex. While Dihydroavenanthramide D interacts directly with skin nerve endings from within to “switch off” physical discomfort and tightness, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, calm, and perfectly protected skin barrier.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments and are completely free of pharmaceutical contaminants. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO
COSMOS
HALAL
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, steroidal side effects, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing neuro-calming actives.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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