Active skincare ingredients
  • Acetyl Hexapeptide-8
  • Shaanxi Huatai Bio-Fine Chemicals Co., Ltd

Acetyl Hexapeptide-8

The Topical Neuro-Peptide Specialist for Smoothing Dynamic Wrinkles

Acetyl Hexapeptide-8, widely known as the “topical botox,” is a high-performance cosmetic grade neuro-peptide. It is specifically designed to target the biochemical mechanisms of wrinkle formation by modulating neurotransmitter release, effectively smoothing fine lines on the forehead and around the eyes.

CAS No.

616204-22-9

Source

High-Purity Peptide Synthesis

Appearance Color

White Powder or Colorless Transparent Liquid

Key Parameter

Peptide Content ≥ 99% (Powder) / 1000ppm (Liquid)

Solubility

Highly Water-Soluble

The Ultimate 100% Farnesol-Free Acetyl Hexapeptide-8: Custom-Engineered for Extremely Sensitive Skin & Zero Sensitization

Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, visibly reduce the depth of wrinkles by up to 30% after 30 days, and significantly decrease the appearance of fine lines within just 15 days of consistent use.

In the demanding realm of luxury anti-aging and non-invasive wrinkle reduction, delivering botulinum toxin-like efficacy without triggering irritation is the ultimate formulation challenge. Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Acetyl Hexapeptide-8 rigorously engineered via advanced solid-phase peptide synthesis to completely eliminate residual solvents and impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By competing with SNAP-25 to destabilize the SNARE complex and inhibit neurotransmitter release, it safely reduces dynamic muscle contractions and smooths expression lines for even the most hyper-reactive skin.

Unlocking Unmatched Business Value

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified Acetyl Hexapeptide-8 dissolves flawlessly into water-based systems, yielding a crystal-clear, water-white, and entirely odorless profile. It ensures zero formula discoloration and guarantees it will never compromise the precise color, fragrance, or aesthetic of your final serums or masks. Exceptionally stable in aqueous solutions, it completely eliminates manufacturing friction and stability nightmares for your R&D teams.

For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, non-invasive active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” or “Instant Lifting” formulations. Empower your brand to market painless, targeted action for crow’s feet, forehead furrows, and nasolabial folds. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver rapid expression line reduction and structural smoothness without irritation or medical procedures.

Product Overview & Core Specifications

  • Appearance: Clear, water-white liquid or high-purity powder (ensures zero formula discoloration)

  • Odor: Odorless (scent neutral)

  • Purity (HPLC): ≥ 98.0%

  • Acetate Content: < 15%

  • Heavy Metals: < 10 ppm

  • Recommended Usage: 3.0% – 10.0% (for the 1000ppm solution)

  • pH Range Stability: Best maintained within a pH range of 3.0 – 6.0 for optimal peptide stability

  • Processing Guidelines: Water-soluble. Should be added to the water phase at the end of the formulation process below 40°C to preserve peak bioactivity.

Ready-to-Use Solutions: The Golden Synergies

Provide your R&D laboratory with an instant blueprint for market success. Our Acetyl Hexapeptide-8 acts as a supreme biological lifting engine, protecting and amplifying the restorative efficacy of companion actives:

  • Acetyl Hexapeptide-8 + Allantoin: The ultimate non-invasive lifting and cellular clearing matrix. Combines the dynamic muscle-relaxing power of Acetyl Hexapeptide-8 with the water-soluble wound-healing properties of Allantoin to rapidly clear micro-traumas and instantly soothe hyper-reactive skin during intensive anti-wrinkle treatments.

  • Acetyl Hexapeptide-8 + Panthenol: A comprehensive “SOS Barrier Rescue” and expression line system. Panthenol floods the stratum corneum with deep, targeted hydration, creating a healthy, non-reactive environment that allows Acetyl Hexapeptide-8 to effectively inhibit neurotransmitter release and smooth deep furrows without triggering dryness or tightness.

  • Acetyl Hexapeptide-8 + Ceramide NP: The absolute structural longevity and “Botox-like” repair complex. While Acetyl Hexapeptide-8 works fundamentally from within to reduce muscle tension and smooth dynamic wrinkles, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, youthful, and perfectly protected skin barrier.

Uncompromising Quality Assurance

Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:

  • ISO

  • COSMOS

  • HALAL

Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.

Upgrade Your Next Bestseller Today

Stop compromising on formula stability, invasive side effects, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing neuro-peptide actives.

Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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