4-Butylresorcinol is a highly effective synthetic derivative of resorcinol that serves as one of the most potent tyrosinase inhibitors currently available in the cosmetic industry. This crystalline powder is specifically designed to target the biological roots of hyperpigmentation by inhibiting the activity of both tyrosinase and tyrosinase-related protein-1 (TRP-1). In modern skincare science, it is widely utilized to treat stubborn dark spots, melasma, and uneven skin tone, providing visible results at significantly lower concentrations compared to traditional brightening agents like kojic acid or arbutin.
Shaanxi Huatai Bio-fine Chemical Co. ensures a robust global supply of 4-Butylresorcinol with a purity level reaching 99.0 percent or higher for premium cosmetic applications. Our manufacturing facility holds prestigious global certifications, including COSMOS, ISO 9001/22000, and HALAL certifications, ensuring that every batch of this 4-Butylresorcinol powder meets the most rigorous safety and regulatory standards for international export. By prioritizing chemical precision and batch-to-batch consistency, we provide formulators with a reliable active that delivers clinically-backed results even in complex cosmetic matrices.
The cost-effectiveness of this ingredient is exceptional for brands looking to achieve medical-tier whitening claims without the high failure rate of unstable actives. This 4-Butylresorcinol powder is inherently stable and offers unmatched efficacy, with research showing it can be several hundred times more effective at inhibiting melanin than conventional alternatives. Its oil-soluble nature allows it to be easily incorporated into the lipid phase of emulsions, providing a luxurious sensory experience while delivering deep-penetrating action to the melanocytes located at the basal layer of the epidermis.
| Item Specification | Technical Details |
| INCI Name | 4-Butylresorcinol |
| CAS Number | 18979-61-8 |
| Appearance | White to Off-white Crystalline Powder |
| Purity (HPLC) | 99.0% Minimum |
| Melting Point | 52.0 – 55.0 Degrees Celsius |
| Solubility | Soluble in Ethanol, Glycols, and Oils |
| Recommended Dosage | 0.1% to 0.3% |
| Shelf Life | 24 Months (Properly Stored) |
4-Butylresorcinol is particularly effective for developing high-potency spot-correcting essences and intensive overnight repair creams. Because it inhibits the melanin synthesis process so efficiently, it is often used as the “hero” active in anti-freckle lines and products targeting age spots in mature skin. Its ability to unify skin tone makes it a perfect addition to targeted treatments that seek to provide long-term skincare benefits alongside immediate aesthetic improvement.
Beyond facial treatments, its stability and potency make it ideal for body-brightening lotions targeting areas of friction-induced hyperpigmentation, such as underarms, elbows, and knees. In the professional salon sector, it is frequently integrated into post-procedure systems to manage the appearance of pigment. This wide application scope allows brands to maximize the utility of the raw material across diverse product categories, from mass-market luxury to clinical specialty skincare.
To maximize the therapeutic results of your product line, we recommend the following synergistic combinations using 4-Butylresorcinol:
| Inhibitor Type | Relative Inhibition Potency | Recommended Dosage |
| 4-Butylresorcinol | Extremely High | 0.1% – 0.3% |
| Kojic Acid | Moderate | 1.0% – 2.0% |
| Beta-Arbutin | Low | 1.0% – 5.0% |
| Vitamin C | Moderate | 2.0% – 10.0% |
Shaanxi Huatai Bio-fine Chemical Co. is a leading specialized manufacturer of high-purity functional ingredients for the global cosmetic industry. Our state-of-the-art production facility ensures consistent batch quality and immediate stock availability for international export. We hold prestigious global certifications including COSMOS, ISO 9001/22000, and HALAL certifications, reflecting our commitment to safety, quality, and regulatory transparency. By providing a full technical dossier including COA, MSDS, and clinical data, we empower brands to develop innovative products with confidence. Our team of expert chemists offers end-to-end formulation consultancy to help you overcome complex stability and sensory challenges.
Q1 Is 4-Butylresorcinol powder easy to dissolve in formulations?
It is an oil-soluble powder with a relatively low melting point (approx 52-55 Degrees Celsius). We recommend dissolving it in the oil phase of your emulsion or in a solvent like Ethoxydiglycol or propanediol during the heating phase to ensure complete integration.
Q2 Can this ingredient be used in daytime products?
Yes, it is chemically stable. However, as with all whitening and brightening products, we strongly recommend pairing it with a broad-spectrum sunscreen to protect the skin and prevent further UV-induced pigmentation.
Q3 How does 4-Butylresorcinol compare to Phenylethyl Resorcinol?
While both are resorcinol derivatives, 4-Butylresorcinol is specifically noted for its extremely high potency in inhibiting both tyrosinase and TRP-1, often allowing for lower effective concentrations in the final formula.
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Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
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