
The Ultimate Melanin Root Inhibitor for Targeted Spot Correction
4-Butylresorcinol (also known as 4-n-Butylresorcinol) is a highly potent cosmetic grade brightening agent recognized for its superior ability to inhibit melanin synthesis at the root. Benchmarked as more effective than many traditional whitening agents, including Phenylethyl Resorcinol (377), it serves as a specialized active ingredients skincare solution for addressing melasma and stubborn dark spots.
| CAS No. | 18979-61-8 |
|---|---|
| Source | High-Purity Cosmetic Synthesis |
| Appearance Color | White to Off-white Crystalline Powder |
| Key Parameter | Purity ≥ 99.0% |
| Solubility | Oil-Soluble / Alcohol-Soluble |
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while delivering a visible reduction in the intensity of stubborn dark spots and pigment clusters within just 8 weeks of consistent use through direct dual-enzyme inhibition.
In the advanced landscape of professional skin lightening and hyperpigmentation correction, delivering clinical-level spot fading without triggering surface irritation is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer established in 2008, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium 4-Butylresorcinol (the industry-renowned “Melasma Nemesis”) rigorously engineered to completely remove residual impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By acting as a highly effective inhibitor of both Tyrosinase and Peroxidase in the melanogenesis pathway, this ultra-pure crystalline active provides professional-grade brightening for even the most hyper-reactive and sensitive skin.

For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Our highly purified 4-Butylresorcinol dissolves flawlessly into the oil phase or suitable solvents, yielding a crystal-clear, water-white, and entirely odorless profile. It ensures zero formula discoloration and guarantees it will never compromise the precise color, fragrance, or aesthetic of your final serums or targeted treatments. Exceptionally stable within recommended parameters, it completely eliminates the manufacturing friction and oxidation nightmares typically associated with high-efficacy brightening agents.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Dermatologist-Grade Brightening,” “Targeted Spot Correction,” and superior melanin suppression that out-performs traditional Arbutin or Kojic Acid. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver flawless skin tone and intense pigment clearance without irritation.
Appearance: Ultra-pure crystalline powder (yields a clear, water-white, invisible profile in formulations)
Odor: Odorless (scent neutral)
Purity: ≥ 99.0%
Melting Point: 51.0°C – 54.0°C
Heavy Metals: < 10 ppm
Recommended Usage: 0.1% – 0.5% (Highly effective at very low concentrations)
pH Range Stability: Best maintained within a pH range of 4.5 – 6.0
Processing Guidelines: Oil-soluble. Should be dissolved in the oil phase or suitable solvents (such as Propanediol) to ensure optimal integration and bioavailability.
Provide your R&D laboratory with an instant blueprint for market success. Our 4-Butylresorcinol acts as a supreme biological brightening engine, protecting and amplifying the restorative efficacy of companion actives:
4-Butylresorcinol + Allantoin: The ultimate spot-correction and cellular clearing matrix. Combines the direct melanin-suppressing power of 4-Butylresorcinol with the water-soluble wound-healing properties of Allantoin to rapidly fade localized pigment clusters and instantly soothe micro-traumas in hyper-reactive skin.
4-Butylresorcinol + Panthenol: A comprehensive “SOS Barrier Rescue” and brightening system. Panthenol floods the stratum corneum with deep, targeted hydration, creating a healthy, non-reactive environment that allows 4-Butylresorcinol to effectively bind to the active sites of melanogenesis enzymes without triggering the irritation associated with aggressive whitening treatments.
4-Butylresorcinol + Ceramide NP: The absolute structural longevity and “Melasma Nemesis” complex. While 4-Butylresorcinol halts the conversion of tyrosine into melanin from within to clear sun and age spots, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, flawlessly even-toned, and perfectly protected skin barrier.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO9001
ISO22000
COSMOS
HALAL
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, oxidized brightening agents, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing clinical spot correctors.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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