Supplier of high-purity functional skin care ingredients

Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Factory

Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Exhibition

Shaanxi Huatai Bio-Fine Chemical Co., Ltd.

Oil-Soluble Glabridin 90%

The Natural Whitening Gold and Potent Tyrosinase Inhibitor

Oil-Soluble Glabridin 90% is a premium whitening active ingredient extracted from the root of Glycyrrhiza glabra. Known in the industry as “whitening gold,” Oil-Soluble Glabridin 90% offers exceptional skin penetration capabilities and highly effective skin brightening. Its core advantages include superior oil solubility for cosmetic formulations, high safety and gentleness without blackthorn irritation, and the ability to inhibit melanin at the source. It is one of the most potent natural inhibitors of tyrosinase currently available for high-end whitening and brightening products.

INCI Name	Glabridin
CAS No.	59870-68-7
Source	Natural Botanical (Licorice Root)
Appearance	White powder
Core Function	Tyrosinase Inhibition, Whitening, Anti-inflammatory, Brightening, Melanin Blocking.

Direct Factory Supply

Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.

Flexible OEM/ODM

Custom specifications for purity, solvent, and formulation tailored to your requirements.

Stable Supply Chain

Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.

Strict QA & Certs

ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.

Direct from the Manufacturer: Premium Oil-Soluble Glabridin 90%
Searching for a highly stable, non-crystallizing whitening active for your lipid-based formulations? Partner directly with Shaanxi Huatai Bio-Fine Chemicals Co. As an industry-leading manufacturer of botanical extracts, we specialized in producing premium Oil-Soluble Glabridin 90% (CAS: 59870-68-7), strictly backed by COSMOS, ISO 9001/22000, and HALAL certifications.
Known as the “Whitening Gold,” our 90% purity Glabridin is expertly engineered for seamless integration into cosmetic oils and emulsions, ensuring superior bioavailability without compromising product stability. Skip the middlemen and secure factory-direct pricing, consistent quality, and comprehensive technical support from R&D to commercial production.

1. Product Overview and Market Relevance

Oil-Soluble Glabridin 90% addresses the global demand for safe, natural, and highly effective skin-lightening agents. Unlike many synthetic alternatives, Oil-Soluble Glabridin 90% provides potent results while maintaining a gentle profile suitable for sensitive skin. As a high-purity active, it is the gold standard for luxury whitening serums, creams, and targeted spot treatments.

2. Technical Highlights and Mechanisms of Action

2.1 Whitening Mechanism

Tyrosinase Inhibition: Oil-Soluble Glabridin 90% acts deep within the skin’s basal layer to inhibit tyrosinase activity, which blocks the synthesis of melanin.
Hydrogen Bonding: Computer molecular docking shows that Oil-Soluble Glabridin 90% binds firmly to the active center of tyrosinase through hydrogen bonds.
Melanin Blockade: By “guarding the door” of the tyrosinase active center, it prevents the raw material (tyrosine) from entering the synthesis process, effectively stopping melanin production.

2.2 Cellular Efficacy

IC50 Value: In tests on B16-F10 melanoma cells, Oil-Soluble Glabridin 90% demonstrated an IC50 value of 18.36 umol/L.
Cell Vitality: Experiments show that Oil-Soluble Glabridin 90% has a measurable impact on the relative cell vitality of B16-F10 cells, correlating with its whitening efficacy.

3. Product Specification and Parameters

The following data represents the standardized specifications for Oil-Soluble Glabridin 90%:

Parameter	Specification Detail
Content	90%
Product Form	White powder
Solubility	Oil-soluble
Suggested Dosage	Solubility rate 0.2%
Shelf Life	24 months
Storage Conditions	Light-proof, ventilated, dry, and airtight space

4. Stability and Formulation Data

Oil-Soluble Glabridin 90% demonstrates excellent stability across various conditions, ensuring it remains effective in finished cosmetic products.

Solubility Stability: Tests involving 2g of Oil-Soluble Glabridin 90% dissolved in 1000g of camellia oil show that the dissolved state remains largely unchanged over time.
Temperature Resilience: The ingredient maintains high stability at temperatures ranging from -18 degrees Celsius to 48 degrees Celsius for periods of 10 hours and 24 hours.

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials for Oil-Soluble Glabridin 90% include:

COSMOS (Natural and Organic Cosmetic Standard)
ISO 9001 Quality Management System
ISO 22000 Food Safety Management System
HALAL Certification
IQNET (The International Certification Network)
Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

High-End Whitening Serums: Using the high purity of Oil-Soluble Glabridin 90% to target stubborn pigmentation.
Brightening Night Creams: Leveraging its deep penetration to restore skin tone during the repair cycle.
Targeted Spot Correctors: Utilizing its tyrosinase blocking mechanism for specific hyperpigmented areas.
Sun Care Support: Included as an anti-inflammatory and preventive whitening agent to counter UV-induced darkening.

7. Frequently Asked Questions (FAQ)

Question	Answer
What is Oil Soluble Glabridin 90 and what are its main benefits in skincare?	Oil Soluble Glabridin 90 is a highly concentrated natural active ingredient extracted from licorice roots, featuring a guaranteed purity of 90 percent. It is renowned as one of the most powerful skin brightening and anti-inflammatory agents in cosmetics. Shaanxi Huatai manufactures this premium extract to help brands develop advanced dark spot correctors and soothing formulations.
What is the botanical source and extraction method used for your Glabridin 90?	Shaanxi Huatai extracts Glabridin 90 strictly from natural Glycyrrhiza glabra (licorice) roots using advanced, eco-friendly separation and purification technologies. This ensures maximum biological activity, consistent quality, and a pure active profile for your high-end cosmetic lines.
Why is it called oil soluble, and how should Glabridin 90 be formulated in emulsions?	Glabridin is naturally lipophilic and dissolves readily in oil phases or appropriate cosmetic glycols. The technical formulation team at Shaanxi Huatai recommends dissolving the powder in the heated oil phase or pre-dissolving it in compatible solvents before adding it to your creams, lotions, or facial oils during manufacturing.
What is the recommended usage rate for Glabridin 90 in cosmetic products?	Because of its exceptional potency at 90 percent purity, the recommended usage rate typically ranges from 0.05 to 0.5 percent depending on the specific product type and target claims. The technical support experts at Shaanxi Huatai are available to provide precise dosage guidelines tailored to your formulation.
Will Glabridin 90 cause discoloration or stability issues in my final cosmetic cream?	When used at recommended active concentrations, Glabridin 90 maintains good stability in properly formulated emulsions. Shaanxi Huatai applies advanced purification processes to minimize color and odor, ensuring your final serums and creams remain stable, elegant, and effective throughout their shelf life.
Can Glabridin 90 be combined with other skin brightening active ingredients?	Absolutely. Glabridin 90 works synergistically with other whitening and antioxidant agents. The formulation team at Shaanxi Huatai frequently assists clients in combining our Glabridin with Niacinamide, Alpha Arbutin, or Vitamin C derivatives to create multi-pathway brightening and anti-aging complexes.
Do you provide the Certificate of Analysis (COA) and MSDS for wholesale bulk orders?	Absolute regulatory compliance and strict quality control are our core standards. Shaanxi Huatai provides comprehensive, batch-specific documentation for every wholesale shipment, including the Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and detailed HPLC purity testing reports.
What is the Minimum Order Quantity (MOQ) and are testing samples available?	To support independent cosmetic formulation labs and commercial manufacturing facilities alike, Shaanxi Huatai offers a highly accessible MOQ starting at just 100 grams to 1kg. We also gladly provide free research testing samples so your team can thoroughly evaluate formulation compatibility before ordering in bulk.

Source our high-purity Oil-Soluble Glabridin 90% for stable, high-efficacy natural whitening, superior tyrosinase inhibition, and advanced clean-label brightening formulations.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

🔬 Apply for a Free Sample: Test the stable, high-efficacy whitening power of Oil-Soluble Glabridin 90% today.

📞 Get a Customized Quote: Discuss bulk orders and high-purity specifications.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Product-related information

Could Oil-Soluble Glabridin Be the Definitive “Whitening Gold” for High-Performance Lipid-Based Skincare?

Jun 01, 2026

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Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.