Active skincare ingredients

Maximizing Whitening Efficacy with Oil-Soluble Glabridin 90% in Cosmetic Formulations

Shaanxi Huatai Bio-fine Chemical Co. ensures premium quality and supply stability with our annual production capacity backed by COSMOS, ISO 9001/22000, and HALAL certifications. Oil-Soluble Glabridin 90% is the gold standard for high-end whitening formulations, offering a highly concentrated form of the bioactive isoflavane found in licorice root. Unlike lower purity extracts, this specification focuses on delivering maximum tyrosinase inhibition with minimal impurities, making it the preferred choice for medical aesthetic brands and luxury skincare lines targeting stubborn pigmentation and age spots.

TECHNICAL SPECIFICATIONS AND PURITY STANDARDS

Our manufacturing facility employs advanced extraction and chromatography technologies to achieve a purity of 90% minimum, resulting in an off-white to white powder that integrates seamlessly into oil-based formulations. This high-purity Oil-Soluble Glabridin 90% powder eliminates the dark brown color associated with crude extracts, allowing formulators to create aesthetically pleasing white creams and clear oil serums without color interference.

Key Technical Parameters

ParameterSpecification
AppearanceWhite to Off-White Powder
Purity (HPLC)90% Minimum
SolubilitySoluble in Ethanol, Butylene Glycol, Propylene Glycol
CAS No.59870-68-7
SourceGlycyrrhiza glabra Root
Loss on DryingLess than 1.0%
Heavy MetalsLess than 10 ppm

APPLICATIONS AND EFFICACY IN COSMETICS

Glabridin

Oil-Soluble Glabridin 90% functions as a potent tyrosinase inhibitor and a strong anti-inflammatory agent. Clinical data suggests that at concentrations as low as 0.05%, it significantly reduces UVB-induced erythema and pigmentation, surpassing the efficacy of Kojic Acid and Arbutin without the associated cytotoxicity.

Primary Applications

Precision Spot Correctors

Targeted treatment sticks and concentrated balms for melasma and localized hyperpigmentation benefit from the high potency of the 90% grade.

Brightening Facial Oils

Its oil-soluble nature makes it perfect for anhydrous facial oils, delivering whitening benefits while nourishing the lipid barrier.

Night Repair Creams

Incorporated into the oil phase of rich night creams, it works overnight to inhibit melanogenesis while the skin repairs itself.

Formulation Advice

Oil-Soluble Glabridin 90% powder is lipophilic. It must be pre-dissolved in a compatible solvent such as 1,3-Butanediol, Propylene Glycol, or cosmetic esters before being added to the oil phase or the emulsion at temperatures below 50 degrees Celsius. To prevent oxidation, we strongly recommend including an antioxidant system, such as Tocopherol or Sodium Metabisulfite, in the formulation.

SYNERGISTIC R&D COMBINATION SUGGESTIONS

To maximize the therapeutic potential and market differentiation of your skincare products, we recommend the following synergistic combinations. These pairings leverage the high purity and lipophilicity of Glabridin 90%:

  1. Drop Icon Oil-Soluble Glabridin 90% + SqualaneCore Benefit: Deep Penetration and Barrier Support.Squalane acts as an ideal carrier for Glabridin, enhancing its penetration into the stratum corneum. This combination creates a lightweight, non-comedogenic whitening oil that is suitable for all skin types.
  2. Lemon Icon Oil-Soluble Glabridin 90% + Tetrahexyldecyl Ascorbate (Oil-Soluble Vitamin C)Core Benefit: Water-Free Potent Brightening.Combining Glabridin with an oil-soluble Vitamin C derivative creates a stable, anhydrous serum. This duo targets pigmentation via multiple pathways while stimulating collagen production, without the oxidation issues of water-based Vitamin C.
  3. Leaf Icon Oil-Soluble Glabridin 90% + BisabololCore Benefit: Soothing Whitening for Sensitive Skin.Inflammation often precedes hyperpigmentation. Bisabolol provides immediate soothing, while Glabridin prevents the pigment formation, making this pair excellent for post-procedure care or sensitive skin lines.
  4. Shield Icon Oil-Soluble Glabridin 90% + Tocopherol (Vitamin E)Core Benefit: Stability and Antioxidant Protection.Vitamin E not only stabilizes Glabridin against oxidation but also works synergistically to neutralize free radicals , enhancing the overall anti-aging profile of the formulation.

COMPLIANCE, COST-EFFECTIVENESS, AND SAFETY

Shaanxi Huatai Bio-fine Chemical Co. provides full technical dossiers, including MSDS, COA, and efficacy data, to facilitate your product registration in the EU and US. While the 90% grade carries a premium price, its extreme potency allows for very low effective dosages (0.02% – 0.1%), resulting in a cost-in-use that is competitive with lower efficacy ingredients. It is non-toxic, non-irritating, and safe for long-term use.

MANUFACTURER INFORMATION

Shaanxi Huatai Bio-fine Chemical Co. is a leading manufacturer dedicated to the research and production of high-purity functional cosmetic ingredients. Our state-of-the-art facility operates under strict quality management systems, holding COSMOS, ISO 9001, ISO 22000, and HALAL certifications. We offer end-to-end solutions, from raw material sourcing to formulation consultancy, ensuring our partners can launch effective, stable, and compliant skincare products.

FREQUENTLY ASKED QUESTIONS

Q1 What is the difference between Glabridin 40% and 90%?

The 90% grade is a highly purified white to off-white powder suitable for high-end clear serums and white creams, whereas the 40% grade is reddish-brown and suitable for colored lotions.

Q2 How should I dissolve Oil-Soluble Glabridin 90%?

It is best dissolved in 1,3-Butanediol, Ethanol, or Propylene Glycol. Ensure it is fully dissolved before adding it to your oil phase.

Q3 Is this ingredient stable in daylight?

Glabridin can be sensitive to light. We recommend packaging the final product in opaque or UV-protective containers and including antioxidants in the formula.

For Bulk Sourcing, Quotations, or Sample Requests:

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

🔬 Apply for a Free Sample: Test the superior efficacy and purity of active skincare ingredients today.

📞 Get a Customized Quote: Discuss bulk orders and high-purity specifications.

Email: [email protected]

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Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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