Hydrolyzed Sodium Hyaluronate (Oligo-HA)

Shaanxi Huatai Bio-fine Chemical Co. provides premium cosmetic grade Hydrolyzed Sodium Hyaluronate, characterized by its ultra-low molecular weight and high biological activity. Our unique advantage lies in our precision enzymatic process, which ensures that these active ingredients skincare are not only small enough for transdermal delivery but also maintain the structural integrity required to activate cellular signals. As the signature choice for “Deep Repair” and “Anti-Wrinkle” lines, our Hydrolyzed HA empowers brands to deliver hydration that isn’t just surface-level, but fundamentally changes the skin’s moisture environment from the inside out.

1. Product Overview & Key Specifications

• Hydrolyzed Sodium Hyaluronate is the “Oligo” form of HA, optimized for maximum skin permeability.

• It is highly valued for its ability to reduce inflammation and promote the skin’s own natural HA production.

2. Technical Highlights & Critical Parameters

• Our Oligo-HA is refined to ensure a narrow molecular weight distribution for predictable and consistent performance.

• Molecular Weight: < 10,000 Da (Customizable ranges available).

• Glucuronic Acid Content: ≥ 45.0%.

• Heavy Metals: < 10 ppm.

• Stability: Excellent stability in aqueous solutions; resistant to high temperatures during formulation.

3. Mechanism of Action (MoA)

• Transdermal Absorption: The ultra-small molecular size allows it to bypass the stratum corneum, carrying moisture and other actives deep into the skin.

• Cellular Signaling: Acts as a signal molecule to trigger the synthesis of endogenous Hyaluronic Acid and Collagen in the dermis.

• Free Radical Scavenging: Provides high-efficiency antioxidant protection at the cellular level, reducing damage from UV exposure.

4. Core Advantages & Market USPs

• Dermal “Filler” Effect: Hydrates the skin from within, leading to a visible “plumping” effect and reduction of deep wrinkles.

• Non-Sticky Texture: Unlike high-molecular HA, Oligo-HA provides an incredibly light, water-like feel with zero tackiness.

• Synergy Booster: Enhances the delivery of other active ingredients by increasing the permeability of the skin barrier.

5. Formulation Guidelines

• Recommended Usage: 0.1% – 0.5% (standard), up to 1.0% for intensive therapeutic serums.

• Processing: Highly water-soluble; can be added to the water phase at any stage of the process.

• pH Range: Best maintained within a pH range of 4.0 – 8.0 for optimal stability.

6. Quality Assurance & Regulatory Confidence

• Our manufacturing facility is ISO 9001/22000 and HALAL certified.

• We strictly adhere to COSMOS approved standards for bio-fermentation and enzymatic processing.

• Every batch of our cosmetic grade Hydrolyzed HA is provided with a full technical dossier, including COA, TDS, and MSDS.

7. Recommended Synergistic Combinations

• Hydrolyzed HA + High-Molecular HA: For a “Dual-Hydration” system that protects the surface while repairing the depths.

• Hydrolyzed HA + Copper Tripeptide-1: To deliver repair signals directly to the dermis for maximum collagen synthesis.

• Hydrolyzed HA + Sodium Polyglutamate (γ-PGA): To maximize NMF production and ensure long-term water locking.

8. Typical Applications & Success Stories

• This ingredient is a core component in “Deep Repair Essences,” “Anti-Aging Eye Creams,” “Hydrating Primers,” and “Post-Laser Serums.”

• Brands utilizing our high-purity active ingredients skincare have successfully marketed “Molecular Hydration” lines that show measurable dermal improvement.

9. Scientific Evidence & Literature Support

• Scientific studies confirm that HA with molecular weights < 10kDa can penetrate the skin within 30 minutes of application.

• Internal lab data confirms a 25% increase in skin elasticity and a significant improvement in the skin’s internal moisture reservoir after 14 days of use.

Partner with the High-Purity Hydrolyzed Sodium Hyaluronate Supplier of Choice.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA and Safety Reports.

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