
The Deep-Penetration Specialist for Transdermal Absorption and Cellular Repair
Hydrolyzed Sodium Hyaluronate, often referred to as Oligo-HA, is a breakthrough cosmetic grade active produced through specialized enzymatic cleavage technology. By reducing the molecular weight to less than 10,000 Daltons (<10kDa), this high-tech ingredient overcomes the penetration barriers of standard Hyaluronic Acid, enabling it to reach the deeper layers of the epidermis and dermis to trigger biological repair and provide profound hydration.
| CAS No. | 9067-32-7 |
|---|---|
| Source | Microbial Fermentation followed by Enzymatic Cleavage |
| Appearance Color | White Crystalline Powder |
| Key Parameter | Molecular Weight < 10,000 Da (typically 3,000–10,000 Da) |
| Solubility | Highly Water-Soluble |
Source directly from manufacturer. Zero middlemen margin, guaranteed bulk competitive pricing.
Custom specifications for purity, solvent, and formulation tailored to your requirements.
Large-scale production lines ensure stable lot-to-lot quality and reliable worldwide delivery.
ISO, Halal, Kosher, and SC certified manufacturing with batch COA test reports.
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, bypass the stratum corneum within 30 minutes, and increase skin elasticity by 25% in just 14 days.
In the advanced landscape of dermatological anti-aging and deep cellular repair, delivering profound dermal hydration without triggering surface irritation is the ultimate formulation challenge. Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium Hydrolyzed Sodium Hyaluronate (Oligo-HA) rigorously engineered via a precision enzymatic process to completely remove impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By maintaining an ultra-low molecular weight, this highly active signal molecule penetrates deep into the dermis to trigger endogenous HA and collagen synthesis, hydrating and repairing hyper-reactive skin from the inside out.
For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and extreme compatibility. Unlike traditional high-molecular HA, our highly purified Oligo-HA provides an incredibly light, water-like feel with zero tackiness. It dissolves flawlessly into the water phase at any stage of the process, yielding a crystal-clear, entirely odorless profile. Highly resistant to high temperatures and stable across a broad pH range, it guarantees it will never compromise the precise aesthetic or stability of your final serums and essences, completely eliminating manufacturing friction for your R&D teams.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, permeable active is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Molecular Hydration” and a true “Dermal Filler” effect. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing moisture therapies that move beyond temporary surface relief to fundamentally reduce deep wrinkles and restore structural vitality.
Appearance: Clear, non-sticky, water-white profile
Odor: Odorless (scent neutral)
Molecular Weight: < 10,000 Da (Oligo form optimized for maximum transdermal permeability)
Glucuronic Acid Content: ≥ 45.0%
Purity: Premium Cosmetic Grade
Heavy Metals: < 10 ppm
Recommended Usage: 0.1% – 0.5% (Standard) / Up to 1.0% (Intensive Therapeutic Serums)
pH Range Stability: Exceptionally stable between 4.0 – 8.0
Processing Guidelines: Highly water-soluble. Can be added directly to the water phase at any stage of manufacturing. Resistant to high-temperature processing.
Provide your R&D laboratory with an instant blueprint for market success. Our Hydrolyzed Sodium Hyaluronate acts as a supreme biological delivery enhancer, protecting and amplifying the restorative efficacy of companion actives:
Hydrolyzed HA + Allantoin: The ultimate deep-tissue regeneration matrix. Combines the transdermal moisture-carrying and cellular signaling capacity of Oligo-HA with the water-soluble wound-healing properties of Allantoin to instantly plump deep dehydration lines and safely soothe micro-traumatized or post-laser skin.
Hydrolyzed HA + Panthenol: A comprehensive “SOS Barrier Rescue” and dermal plumping system. Panthenol floods the upper stratum corneum with targeted barrier repair, while Oligo-HA penetrates the deeper dermal layers to rebuild the skin’s internal moisture reservoir, creating a perfectly balanced, non-reactive environment that rapidly halts inflammatory triggers.
Hydrolyzed HA + Ceramide NP: The absolute structural longevity and 3D hydration complex. While our ultra-low molecular weight HA hydrates the dermal layers from within and triggers endogenous collagen synthesis, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface—sealing the barrier tight to ensure the deep moisture never escapes.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our bio-fermented and enzymatically processed active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO
COSMOS
HALAL
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
| Question | Answer |
| What is the molecular weight of your Hydrolyzed Sodium Hyaluronate (Oligo HA) and how does it differ from standard HA? | Standard Hyaluronic Acid sits on the skin surface, whereas the Oligo HA produced by Shaanxi Huatai has an ultra-low molecular weight (typically <10,000 Da or even <5,000 Da). This allows it to penetrate deep into the dermis for profound hydration, cellular repair, and anti-aging benefits, rather than just superficial moisturizing. |
| Is your Oligo Hyaluronic Acid produced via enzymatic degradation or chemical cleavage? | Shaanxi Huatai utilizes advanced bio-enzymatic degradation technology to produce our Hydrolyzed Sodium Hyaluronate. This highly controlled natural process ensures superior purity, maintains the integrity of the HA structure, and avoids harsh chemical residues, making it exceptionally safe for sensitive skin formulations. |
| Is Hydrolyzed Sodium Hyaluronate water-soluble, and how should it be formulated? | Yes, the Oligo HA from Shaanxi Huatai exhibits excellent water solubility and forms a clear, non-viscous solution. It can be effortlessly incorporated into the aqueous phase of your cosmetic formulations (toners, serums, masks) at room temperature, without the clumping or thickening issues often associated with high molecular weight HA. |
| What is the recommended usage rate for Oligo HA in anti-aging and deep hydration skincare? | The standard recommended usage rate typically ranges from 0.1% to 0.5%, depending on the specific efficacy claims of your final product. The R&D team at Shaanxi Huatai can provide precise formulation guidance to help you maximize its transdermal absorption and skin-rejuvenating properties. |
| What are the primary cosmetic benefits of using Hydrolyzed Sodium Hyaluronate over standard Hyaluronic Acid? | Due to its ultra-low molecular weight, it crosses the stratum corneum to deliver deep cellular hydration, scavenge free radicals, reduce inflammation, and stimulate natural collagen synthesis. Global formulators trust Shaanxi Huatai‘s Oligo HA to create high-performance anti-aging and intensive repair serums. |
| Do you provide a Certificate of Analysis (COA) and MSDS for wholesale bulk orders? | Absolutely. Uncompromising quality assurance is our standard. Shaanxi Huatai provides comprehensive, batch-specific documentation, including the Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and molecular weight distribution reports, ensuring seamless QA/QC compliance for your brand. |
| What is the Minimum Order Quantity (MOQ) for bulk Oligo HA, and can I get a sample? | To support cosmetic formulators and R&D labs of all scales, Shaanxi Huatai offers a highly accessible MOQ of just 1kg. We also gladly provide 10g-20g free samples for your formulation compatibility, sensory evaluation, and stability testing. |
| Why should I source Hydrolyzed Sodium Hyaluronate directly from your factory in China? | Sourcing directly from a primary manufacturer like Shaanxi Huatai ensures you bypass middleman markups, securing highly competitive factory-direct pricing. Furthermore, we guarantee strict batch-to-batch consistency, direct access to our technical support team, and rapid global shipping (typically dispatched within 3-5 working days). |
Stop compromising on formula stability, sticky humectants, and ingredient purity. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing transdermal hydration.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Safety Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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