
Glutathione (GSH), specifically the L-Reduced form, is a naturally occurring tripeptide (L–cysteine, L–glutamic acid, and glycine) often called the body’s “Master Antioxidant.” It is critical for cellular defense, detoxification, and immune function. Topically, GSH delivers powerful skin-lightening, anti-aging, and detoxification benefits by directly neutralizing free radicals and significantly shifting the melanin production pathway from dark (eumelanin) to light (pheomelanin) pigment.
| INCI Name | Glutathione |
|---|---|
| CAS No. | 70-18-8 |
| Source | Biotechnological Fermentation |
| Appearance | White crystalline powder |
| Core Function | Skin Brightening, Master Antioxidant, Cellular Detoxification, Anti-aging, Tyrosinase Inhibition |
Clinically proven to reduce skin sensitivity markers by 40% within 48 hours, while acting as the body’s “Master Antioxidant” to actively inhibit tyrosinase, modulate the melanogenesis pathway towards lighter pheomelanin, and neutralize ROS at the cellular level with zero irritation.
In the advanced landscape of dermatological brightening and cellular detoxification, delivering clinical-strength results without the instability or sensitivity typical of high-potency actives is the ultimate formulation challenge. As a specialized high-purity cosmetic active ingredient manufacturer established in 2008, Shaanxi Huatai Bio-Fine Chemicals Co. delivers a premium L-Reduced Glutathione (GSH) rigorously engineered to completely remove residual impurities. Built to be 100% farnesol-free, it establishes a flawless safety profile that eradicates the risk of ingredient-induced sensitization. By functioning as a potent, biocompatible tripeptide, this ultra-pure active provides professional-grade melanin modulation, intensive cellular DNA protection, and profound tissue revitalization for even the most hyper-reactive, compromised skin.
For Global OEM/ODM Innovators: Achieve ultimate formulation elegance and precision. Our 98% Reduced Glutathione is engineered for exceptional water solubility and purity, ensuring seamless integration into your high-performance aqueous phase serums and clinical whitening systems. It offers a refined, water-white profile that ensures no unintended discoloration of your final product. Exceptionally potent, its high purity allows for transformative brightening results at lower dosage rates, optimizing your production costs while maximizing the efficacy profile for your R&D laboratories.
For High-End Beauty Brands: Elevate your market positioning and clinical claims. This ultra-pure, standardized tripeptide is the signature choice for strict “Clean Beauty” mandates and highly tolerable “SOS Emergency Repair” formulations. Empower your brand to market “Master Antioxidant Defense,” “Cellular Detoxification,” and “Clinical Melanin Modulation” without the risks linked to harsh synthetic whitening agents. Capture the fierce loyalty of consumers demanding highly potent, non-sensitizing clinical solutions that deliver flawless radiance, profound structural support, and essential everyday defense.
Appearance: High-purity, white crystalline powder (optimized for rapid dispersion)
Active Content / Purity: ≥ 98.0% (L-Reduced Form; biological activity verified)
Heavy Metals: < 10 ppm
Arsenic: < 1 ppm
Recommended Dosage: 0.5% – 2.0% (Highly effective for brightening and intensive spot reduction)
pH Range Stability: Best maintained within an optimal slightly acidic pH of 5.0 – 6.0
Processing Guidelines: Highly water-soluble. To ensure maximum stability and prevent oxidation to GSSG, incorporate during the cooling phase (below 40°C) and utilize a low-oxygen formulation environment. Store in a cool, dark, dry place with inert gas protection.
Provide your R&D laboratory with an instant blueprint for market success. Our Reduced Glutathione acts as a supreme biological defense engine, protecting and amplifying the restorative efficacy of companion actives:
Glutathione + Vitamin C (Ascorbic Acid derivative): The ultimate “Antioxidant Recycling” matrix. Glutathione acts as the master regulator, regenerating spent Vitamin C molecules to extend their effective life in the skin, resulting in an exponentially more potent brightening and anti-aging effect.
Glutathione + Allantoin: The “Detox & Repair” complex. Combines the targeted cellular detoxification of Glutathione with the water-soluble wound-healing properties of Allantoin to rapidly resolve surface oxidative stress, calm inflammation, and restore equilibrium to hyper-reactive skin.
Glutathione + Ceramide NP: The absolute structural longevity and “Clean Beauty Radiance” complex. While Glutathione works fundamentally from within to modulate melanin production and scavenge ROS, Ceramide NP safely and physically rebuilds the skin’s depleted lipid cement on the surface, ensuring a resilient, brilliantly illuminated, and perfectly defended skin barrier.
Formulate with absolute regulatory confidence. We strictly adhere to global cosmetic safety benchmarks, ensuring our active ingredients pass the most stringent toxicological assessments. Our state-of-the-art manufacturing facility operates under the highest global standards, fully certified by:
ISO9001
ISO22000
COSMOS
HALAL
IQNET
Every batch is supported by a comprehensive technical dossier to streamline your global compliance, supply chain transparency, and regulatory filing processes.
Stop compromising on formula stability, purity, and ingredient-induced irritation. Protect your consumers and elevate your product lines with the global standard in highly stable, non-sensitizing clinical antioxidant actives.
Claim your High-Purity, Odorless Sample Now and upgrade your next blockbuster SOS repair formula! Contact our technical sales team immediately to secure your free lab sample, request a customized bulk quote, and access the full Technical Dossier (TDS, MSDS, COA, and Clinical Efficacy Reports).
Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.




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