Glabridin

Shaanxi Huatai Bio-Fine Chemical is a professional manufacturer of Glabridin (CAS No. 59870-68-7), providing a comprehensive range of specifications from 1% to 99% purity to meet diverse cosmetic formulation needs.

Our flagship products include Glabridin 40% (White Powder) for high-performance whitening and High Purity 90%, 98%, 99% Glabridin for luxury skincare lines. Unlike standard market options, our extraction process ensures maximum stability and anti-inflammatory activity. We also offer customized solutions, including 10% Water-Soluble Liquid for easier application. all batches come with complete COA and HPLC testing reports.

1. Product Overview & Key Specifications

Glabridin is the highly effective, natural lightening and anti-spot compound derived from Licorice Root. Globally recognized for its safety and potent efficacy, our Glabridin is a multi-functional ingredient that meets the strictest standards of global premium cosmetic manufacturers.

2. Technical Highlights & Critical Parameters

2.1 Customizable Grade Options

Storage Condition: Store in a sealed container, away from light, in a cool, dry, and ventilated place.

3. Mechanism of Action (MoA)

• Tyrosinase Inhibition: Glabridin acts as a non-competitive Tyrosinase inhibitor, halting the critical step of melanogenesis.
• Data Summary: Glabridin 99% and 40% grades demonstrate a clear dose-dependent inhibitory effect on Tyrosinase activity, with higher purity correlating to stronger whitening and anti-spot efficacy.
• Anti-Photoaging & UVB Defense: Glabridin effectively suppresses the development of skin aging and inflammatory processes induced by UVB radiation.

4. Core Advantages & Market USPs

4.1 Competitive Edge for Your Brand

• Purity-Driven Efficacy: Our high-purity 99% Glabridin ensures maximum biological activity, delivering reliable and visible results.
• Regulatory & Safety Confidence: Backed by complete safety reports and rigorous sourcing standards (low heavy metals/pesticides).
• Versatile Solubilization: Offering Water, Alcohol, and Oil-soluble grades to simplify formulation across all product types (serums, creams, masks, powders).
• Patented Technology: Manufactured under Patent No. ZL201210501850.0, ensuring a differentiated, high-quality product.

5. Formulation Guidelines

5.1 Glabridin Recommended Dosage and Compatibility

• Recommended Use Level (99% Powder): 0.01% – 0.5%.
• Dissolution Advice: High-purity powder should be pre-dissolved in the appropriate solvent (Alcohol or Oil phase) before emulsification.
• Compatibility: Highly compatible with common cosmetic bases. We provide mature formulation advice for various systems (Aqueous, Alcohol, Emulsions).

6. Quality Assurance & Regulatory Confidence

We are committed to the highest standards of quality and regulatory compliance, reducing your market entry risk.

6.1 Certificate Section

Our quality and safety credentials include:

• COSMOS (Natural and Organic Cosmetic Standard)
• ISO 9001 Quality Management System
• ISO 22000 Food Safety Management System
• HALAL Certification
• IQNET (The International Certification Network)
• Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

7. Recommended Synergistic Combinations

Leverage Glabridin’s synergy to create next-generation multi-functional products:

• Glabridin + Niacinamide: The ultimate melanin blocking and accelerating complex for all-pathway whitening.
• Glabridin + Ceramide: Combines powerful lightening with skin barrier repair for a soothing, high-efficacy formula.

8. Typical Applications & Success Stories

Glabridin is validated by global market leaders.

• Industry Validation: “Used in whitening formulations for premium brands in Asia & Europe.”
• Target Product Categories: High-Efficacy Spot Correctors, Brightening Serums, Anti-Aging Day Creams.

9. Scientific Evidence & Literature Support

Based on internal lab summaries, our Glabridin demonstrates superior efficacy through two core mechanisms:

9.1 Research Abstracts

• Tyrosinase Inhibition: Testing on Glabridin 98%, 90%, and 40% grades confirmed a clear dose-dependent relationship between purity and efficacy in inhibiting tyrosinase and $A375$ cell proliferation. Higher Glabridin content yields superior whitening and anti-spot effects.
  
• Anti-Photoaging & UVB Defense: A compound formula containing 0.2% Glycyrrhizic acid and 0.1% Glabridin effectively suppresses skin aging caused by UVB radiation. The combined formulation shows a strong synergistic effect, proving superior to using a single ingredient.

10. Stability and Safety Data Summary

Our Glabridin raw material is tested to ensure excellent storage and formulation stability.

• Storage Stability: Powder grades guarantee a 24-month shelf life when stored under recommended conditions (cool, dry, sealed, away from light).
• Safety Profile: Full safety report available upon request, confirming low irritation and non-toxic status at recommended use levels.

11. Frequently Asked Questions

Q1: What is the optimal Glabridin Recommended Dose for maximum effect?

A: For our 99% powder, the recommended dosage is 0.01% – 0.5%.

Q2: Is your high purity Glabridin prone to oxidation in formulations?

A: Our product has high inherent stability (Delta E < 1.0). We provide detailed Glabridin Stability Testing data.

Q3: Can Glabridin be used in O/W (Oil-in-Water) Emulsions?

A: Yes. Our technical team can provide precise Glabridin Solubility guidelines for O/W systems.

Q4: Do you offer bulk supply and competitive pricing for Glabridin Exporter clients?

A: Absolutely. We offer scalable bulk supply and flexible MOQ for global clients. Contact our sales team for a customized quote and to discuss our Glabridin Global Supply capacity.

Partner with the High-Purity Glabridin Supplier of Choice.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA and Safety Reports.

🔬 Apply for a Free Sample: Test our superior purity in your lab today.

📞 Get a Customized Quote: Discuss bulk orders and tailored specifications (1% to 99%).