Active skincare ingredients

MAXIMIZING SKINCARE EFFICACY WITH DIPOTASSIUM GLYCYRRHIZINATE POWDER

Shaanxi Huatai Bio-fine Chemical Co. ensures every batch meets global safety standards, supported by our COSMOS, ISO 9001/22000, and HALAL certifications. Dipotassium Glycyrrhizinate (DG) is a premier water-soluble salt derived from licorice root, celebrated for its “cortisone-like” soothing effects without the associated side effects. As a dipotassium glycyrrhizinate powder with purity reaching up to 99%, it acts as a critical anchor in formulations designed for sensitive skin, effectively mitigating irritation caused by environmental stressors or active chemical exfoliants.

TECHNICAL SPECIFICATIONS AND PURITY

Dipotassium Glycyrrhizate

Our manufacturing facility utilizes advanced extraction protocols to produce a high-purity white powder that is fully water-soluble, ensuring seamless integration into aqueous systems. Unlike crude extracts, our 99% purity grade guarantees minimal heavy metal content and optimal stability, making it suitable for even the most stringent Japanese cosmetic standards.

Key Technical Parameters Appearance: White Powder Purity (HPLC): 73% / 75% / 99% CAS No.: 68797-35-3 Solubility: Fully Water-Soluble Shelf Life: 24 Months Safety Status: FDA GRAS Recognized

APPLICATIONS AND EFFICACY

Dipotassium Glycyrrhizinate functions as a multi-modal agent, offering anti-inflammatory, anti-allergic, and sebum-regulating benefits. Clinical assessments using 5% SDS patch tests have demonstrated that DG significantly reduces skin redness, stinging, and thermal sensation in a dose-dependent manner.

Primary Applications

  1. Soothing Toners: Instantly calms redness and balances skin pH.
  2. Acne Treatments: Reduces inflammation associated with Propionibacterium acnes while regulating oil.
  3. Post-Procedure Care: Accelerates recovery after chemical peels or laser treatments.
  4. Oral Care: Used in toothpaste for its anti-inflammatory effects on gum tissue.

Formulation Advice Because it is a highly stable salt, dipotassium glycyrrhizinate powder can be added directly to the water phase of a formulation at room temperature or during the heating phase. It is compatible with a wide pH range (typically 3.0-6.0) and works well with anionic and non-ionic emulsifiers. The recommended dosage is generally 0.1% to 0.5%, though higher concentrations (up to 5%) can be used for therapeutic-grade products.

SYNERGISTIC R&D COMBINATION SUGGESTIONS

To enhance the commercial appeal and functional breadth of your skincare line, we recommend the following synergistic combinations:

  1. Dipotassium Glycyrrhizinate + Salicylic Acid Core Benefit: Irritation-Free Acne Control. Salicylic Acid exfoliates pores but can cause redness. Adding DG mitigates this irritation, allowing for higher efficacy acne treatments that remain gentle on the skin barrier.
  2. Dipotassium Glycyrrhizinate + Hyaluronic Acid Core Benefit: Deep Hydration with Calming Action. This combination addresses “dehydrated sensitivity.” Hyaluronic Acid locks in moisture while DG prevents the stinging sensation often associated with dry, cracked skin.
  3. Dipotassium Glycyrrhizinate + Centella Asiatica Core Benefit: Ultimate Wound Repair. Known as the “Cica-Soothing Complex,” this pairing accelerates the healing of compromised skin barriers, making it ideal for recovery balms and post-sun lotions.
  4. Dipotassium Glycyrrhizinate + Glabridin Core Benefit: Safe Whitening for Sensitive Skin. While Glabridin inhibits melanin, DG suppresses the inflammation that triggers pigment production. Together, they offer a comprehensive approach to brightening that is safe for reactive skin types.

COMPLIANCE, COST-EFFECTIVENESS, AND SAFETY

Shaanxi Huatai Bio-fine Chemical Co. provides complete technical dossiers, including COA, MSDS, and safety reports, to streamline your regulatory compliance in the EU and US. Recognized as GRAS by the FDA, our Dipotassium Glycyrrhizinate allows brands to market their products with “Hypoallergenic” and “Dermatologist Tested” claims confidence. Its low effective dosage (starting at 0.1%) ensures a high cost-performance ratio, adding premium therapeutic value without significantly impacting the cost of goods sold.

MANUFACTURER INFORMATION

Shaanxi Huatai Bio-fine Chemical Co. is a leading specialist in the production of high-purity licorice derivatives. Our state-of-the-art facility is certified under COSMOS, ISO 9001, ISO 22000, and HALAL standards, ensuring that our ingredients meet the diverse needs of the global beauty industry. We offer flexible solutions, including various purity grades (73%, 75%, 99%) to match your specific formulation requirements and budget.

FREQUENTLY ASKED QUESTIONS

Q1 Is Dipotassium Glycyrrhizinate powder difficult to dissolve?

No, it is highly water-soluble and dissolves easily in the aqueous phase at ambient temperatures, making it one of the easiest actives to formulate with.

Q2 Can this ingredient be used in leave-on products?

Yes, it is widely used in leave-on creams, serums, and lotions due to its excellent safety profile and lack of skin irritation even with prolonged contact.

Q3 What is the optimal pH range for formulations containing this ingredient?

It is stable across a broad pH range, but for optimal efficacy and stability, we recommend formulating within a pH of 3.0 to 6.0

For Bulk Sourcing, Quotations, or Sample Requests:

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🔬 Apply for a Free Sample: Test the superior efficacy and purity of active skincare ingredients today.

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Why choose us

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

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