Dipotassium Glycyrrhizate Data Sheet: Purity, Safety, and Clinical Efficacy
Dipotassium Glycyrrhizate, identified by CAS No: 68797-35-3, is a high-performance Functional Skincare Ingredient recognized for its powerful anti-inflammatory, soothing, and anti-allergic properties. Sourced from botanical raw materials, DG is an essential compound for therapeutic and sensitive skin product lines.
Huatai Bio a leading supplier, ensures that our DG product line, including 73%, 75%, and 99% purity grades, meets stringent global quality standards, specifically focusing on ultra-low heavy metal content.
Product Specifications and Handling
| Content Grade | Product State | Solubility | Recommended Usage | Shelf Life | Storage Conditions |
| 73% | White Powder | Water-Soluble | 0.1% – 5% | 24 Months | Avoid light, ventilated, dry sealed space |
| 75% | White Powder | Water-Soluble | 0.1% – 5% | 24 Months | Avoid light, ventilated, dry sealed space |
| 99% | White Powder | Water-Soluble | 0.1% – 5% | 24 Months | Avoid light, ventilated, dry sealed space |
Product Characteristics: DG is a functional natural botanical component that excels in formulation due to its Water-Soluble nature and White Powder form, ensuring high aesthetic compatibility in clear or light-colored matrices.
Clinical Efficacy Proof: SDS Irritation Mitigation
A key measure of DG’s soothing power is its ability to mitigate irritation from common surfactants like Sodium Dodecyl Sulfate (SDS).
SDS Stimulation Sensory Score Results (Tab. 3):
The test, conducted on volunteers with a compromised skin barrier (5% SDS patch application), showed the effect of different DG concentrations on sensory discomfort:
| DG Concentration | Itchiness Score | Stinging Score | Burning Score |
| Untreated | 9 | 8 | 8 |
| 0.5% DG | 2 | 2 | 1 |
| 0.7% DG | 1 | 0 | 0 |
Conclusion: The experimental data conclusively shows that DG significantly reduces SDS-induced skin irritation. The sensory scores for stinging and burning are entirely eliminated at the 0.7% DG concentration, demonstrating optimal efficacy for acute irritation relief.
Safety and Regulatory Compliance
DG is one of the most trusted anti-inflammatory ingredients due to its robust safety profile:
- US FDA GRAS: Listed by the United States Food and Drug Administration as Generally Recognized as Safe (GRAS).
- CIR Approval: EU cosmetics directives and the CIR Expert Panel recognize DG as a safe ingredient for OTC personal care products.
- Clinical Safety: Clinical tests confirm that DG does not penetrate or irritate the skin and is safe without side effects.
- Heavy Metal Control: Huatai Bio specifically adheres to the Japanese cosmetic standard for production, ensuring heavy metal residues are strictly controlled to levels well below the acceptable threshold, making it highly suitable for sensitive cosmetic formulations.
By utilizing Huatai Bio’s high-purity Dipotassium Glycyrrhizate, you gain a clinically verified active that ensures product safety, compliance, and superior anti-inflammatory results.
Contact Huatai Bio
Access the full technical file and secure your supply of certified Dipotassium Glycyrrhizate.
Contact our technical team today to obtain complete technical documentation, request a free sample of our 73%, 75%, or 99% powder, or receive an exclusive quotation tailored to your production volume.
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Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.
Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.
Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.
Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.
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