Active skincare ingredients
  • Phloretin
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Products
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Factory
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Exhibition
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd.

Phloretin

A Dihydrochalcone Compound with Superior Whitening and Anti-inflammatory Efficacy

Phloretin is a dihydrochalcone compound and a type of natural phenol. Extracted from peels or root barks of apples, it is a new natural skin whitening agent. Phloretin helps anti-acne as it weakens estrogen activity. This ingredient is provided at a high purity of 98 Percent as a white powder, making it suitable for advanced cosmetic and dermatological applications.

CAS No.

60-82-2

Source

Apple peels or root barks

Appearance

White Powder

Active Content

98 Percent

Core Function

Skin Whitening, Anti-inflammatory, Immunosuppressive, Antioxidant

Solubility

Soluble in ethanol, 1,3-butanediol etc. Not dissolved in water.

Maximize your formulation’s efficacy with our 98% high-purity Phloretin, a natural polyphenolic antioxidant that not only neutralizes free radicals but also acts as a powerful penetration enhancer for other active ingredients. As a specialized manufacturer, Shaanxi Huatai Bio provides consistent bulk supply of premium white-to-off-white Phloretin powder, backed by COSMOS certification and full technical dossiers (COA/MSDS/TDS) to ensure global regulatory compliance.

1. Product Overview & Market Relevance

Phloretin is a high-performance bioactive compound primarily extracted from the root bark and fruit peel of apples. It is celebrated in the luxury skincare market for its triple-action benefits: antioxidant, anti-inflammatory, and skin brightening.

  • Superior Bioactivity: Effectively inhibits the activity of melanocytes and prevents sebum overproduction, making it ideal for brightening and anti-acne formulations.

  • Advanced Penetration: Unique molecular structure that helps improve the transdermal delivery of synergistic actives like Vitamin C and Ferulic Acid.

  • Factory-Direct Quality: We offer an ultra-refined 98% purity grade with strict control over heavy metals and impurities, ensuring a stable and clean profile for your final products.

2. Technical Highlights and Critical Parameters

2.1 Mechanism of Action (MoA)

  • Skin Whitening: Inhibits tyrosinase activity. Its inhibiting tyrosinase ability is reported to be better than arbutin and kojic acid. The blend of them can greatly improve the inhibition ratio of tyrosinase, about 100 Percent.
  • Anti-inflammatory and Immunosuppressive: NO production and phagocytosis rate of macrophages can be significantly reduced by phloretin.
  • Antioxidant: Phloretin can remove free radicals in the skin, effectively prevent aging, cell mutation, accelerate cell metabolism, reduce wrinkles, enhance the skin supporting structure, and immunity to UV light.

2.2 Standard Technical Specifications

ParameterSpecification (98 Percent Grade)
Specification98 Percent
AppearanceWhite Powder
Dosage (Recommendation)5 ‰ – 1 %
SolubilitySoluble in ethanol, 1,3-butanediol etc. Not dissolved in water.
Shelf Life24 months when properly stored
StorageStore in tightly sealed and preferably full containers in cool, dry and ventilated area.

3. Market Positioning and Core Advantages

  • Superior Whitening Potential: Clinical data suggests 3 Percent Phloretin cream is superior to 3 Percent Arbutin.
  • Immunosuppressive Properties: The results show that phloretin might be developed into a new immunosuppressive drug.
  • Broad Protection: Effective in UV-induced pigmentation prevention and comprehensive anti-aging benefits.

4. Formulation Guidelines

  • Integration Phase: Must be dissolved in lipid-soluble solvents like ethanol or 1,3-butanediol, as it does not dissolve in water.
  • Dosage: Recommended dosage ranges from 5 Percent to 1 Percent.
  • Storage: Store in a cool, dry, and ventilated area to maintain the 24 month shelf life.

5. Quality Assurance and Regulatory Confidence

Our quality and safety credentials include:

  • COSMOS (Natural and Organic Cosmetic Standard)
  • ISO 9001 Quality Management System
  • ISO 22000 Food Safety Management System
  • HALAL Certification
  • IQNET (The International Certification Network)
  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

6. Typical Applications

  • Skinceuticals: Phloretin CF.
  • Cosmetic Skin Solutions: Phloretin CF Serum Advanced Formula +.
  • General Cosmetics: Whitening creams, anti-acne treatments, anti-aging serums.

7. Scientific Evidence Summary

  • Skin Pigmentation: The results suggest that 3 Percent phloretin cream acts on skin pigmentation in the late phase after UV-induced and it is superior to 3 Percent arbutin.
  • Dose-Dependent Whitening: The MI value trend shows that 0.5 Percent, 1 Percent, and 3 Percent phloretin cream inhibit the formation of dark spots and the ability increase as the concentration increasing, there’s a dose-dependent trend. The b value figure also shows that the efficacy of 3 Percent concentration phloretin cream is better than 0.5 Percent and 1 Percent. The higher the concentration, the better the whitening effect.
  • Immune Response: The results showed that phloretin significantly inhibited the proliferation of T lymphocytes and the PI reduced from 1.4 \pm 0.13 to 1.34 \pm 0.16, 1.19 \pm 0.12 and 1.07 \pm 0.06, respectively.

8. Phloretin FAQ

Frequently Asked Questions (FAQ)Expert Answers
Where to buy bulk Phloretin powder directly from a manufacturer?Shaanxi Huatai is a professional manufacturer and supplier of cosmetic grade Phloretin in China. We supply high purity bulk materials to global skincare brands with reliable quality and fast international shipping.
Is your Phloretin powder naturally derived or synthetic?Shaanxi Huatai provides high-purity natural Phloretin extracted from plant sources such as apple bark and peel. It is widely preferred by formulators looking for high-performance antioxidant ingredients for clean beauty.
What are the main cosmetic benefits of Phloretin?The Phloretin manufactured by Shaanxi Huatai is a potent natural antioxidant and skin brightener. It helps neutralize free radicals, reduce hyperpigmentation, improve skin absorption of active ingredients, and protect against environmental damage.
Can Phloretin be combined with Vitamin C and Ferulic Acid in serum formulations?Yes, Phloretin acts synergistically with Vitamin C and Ferulic Acid to significantly boost overall antioxidant efficacy. Shaanxi Huatai supplies high-stability Phloretin ideal for formulating premium skin-brightening serums.
Why choose Shaanxi Huatai as your China Phloretin supplier?As a direct manufacturing factory in China, Shaanxi Huatai offers competitive wholesale prices, strict quality control, excellent batch-to-batch consistency, and direct technical support without middleman markups.
What quality documents do you provide for bulk Phloretin orders?When you order bulk Phloretin from Shaanxi Huatai, we supply a complete technical documentation package including the Certificate of Analysis (COA), MSDS, and detailed product specification sheets for your quality assurance.
Can I request a sample of Phloretin for laboratory testing?Yes, Shaanxi Huatai supports global cosmetic formulators with sample quantities. Your R&D team can evaluate the purity, solubility, and formulation stability in your laboratory prior to placing a commercial wholesale order.
What is the standard lead time for international bulk shipping?Shaanxi Huatai maintains a stable stock of active raw materials. For standard wholesale orders of Phloretin, we arrange prompt shipment by air or sea freight to keep your manufacturing schedule running on time.

 

Source our 98 Percent Phloretin for advanced skin whitening and anti-inflammatory formulations.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

🔬 Apply for a Free Sample: Test the superior efficacy and purity of Phloretin today.

📞 Get a Customized Quote: Discuss bulk orders and high-purity specifications.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

Laissez un message