Active skincare ingredients
  • Adenosine
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Products
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Factory
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd. Exhibition
  • Shaanxi Huatai Bio-Fine Chemical Co., Ltd.

Adenosine

The Cell Regulator for Anti-Wrinkle and Anti-Hair Loss Efficacy

Adenosine is a potent ingredient that regulates various physiological activities, including cell growth, differentiation, and metabolism. It is highly valued for its ability to enhance skin elasticity and tightness, and to awaken scalp and hair vitality. Adenosine is used to improve wrinkles and moisturizing effects.

CAS No.

58-61-7

Source

Nucleoside

Appearance Color

White Powder

Key Efficacy

Anti-Wrinkle, Skin Tightening, Anti-Hair Loss, Cell Activation

Purity

98% (Standard Grade)

Solubility

Water Soluble

1. Product Overview & Key Specifications

Adenosine can promote skin cell and fibroblast activity, stimulate the synthesis of collagen and elastic fibers, and thus help alleviate fine lines and wrinkles (such as crow’s feet and nasolabial folds). Studies on cosmetics containing Adenosine have demonstrated clinical improvements in wrinkles and moisturizing effects.

2. Technical Highlights & Critical Parameters

2.1 Adenosine Core Efficacy

  • Anti-Wrinkle and Firming: Improves skin elasticity and tightness. Results show skin care products containing Adenosine increase stratum corneum water content, reduce TEWL (transepidermal water loss), and improve crow’s feet.
  • Anti-Hair Loss (Anti-Androgenic): Stimulates hair papilla cells to express mesenchymal cell-derived growth factor KGF (FGF-7) and keratinocyte-derived growth factor.
  • Cell Regulation: Regulates various physiological activities, including cell growth, differentiation, and metabolism.

2.2 Customizable Grade Options (Product Specifications)

ContentProduct StateSolubilityRecommended DosageShelf lifeStorage Conditions
98%White PowderWater Soluble0.1%-5.0%24 monthsAvoid light, ventilation, dry, in a sealed space

3. Mechanism of Action (MoA)

Adenosine’s mechanism involves cell activation and growth factor expression:

  • Collagen/Elastin Synthesis: Promotes skin cell and fibroblast activity, stimulating the synthesis of collagen and elastic fibers.
  • Hair Growth Factors: In in vitro experiments, Adenosine can stimulate hair papilla cells to express mesenchymal cell-derived growth factor KGF (FGF-7) and keratinocyte-derived growth factor, acting via KGF-mediated signaling pathways.

4. Core Advantages & Market USPsAdenosine extract

4.1 Competitive Edge for Your Brand

  • Dual Efficacy: Highly sought-after ingredient for both advanced anti-wrinkle facial care and clinical anti-hair loss products.
  • Clinically Proven Hair Loss Efficacy: In a 12-month study on female hair loss, the Adenosine group had a faster rate of growing hair and higher hair density compared to placebo.
  • Water Soluble Powder: The $98\%$ white powder grade is water-soluble, allowing for easy incorporation into various aqueous formulas.
  • Moisture Retention: Demonstrated improvement in stratum corneum water content and reduction of $\text{TEWL}$.

5. Formulation Guidelines

  • Recommended Use Level: 0.1%-5.0%.
  • Dissolution Advice: Easily soluble in water.
  • Ideal Use: High-end anti-aging serums, eye creams, toners, and specialized anti-hair loss shampoos and serums.

6. Quality Assurance & Regulatory Confidence

We are committed to the highest standards of quality and regulatory compliance.

6.1 Certificate Section

Our quality and safety credentials include:

  • COSMOS (Natural and Organic Cosmetic Standard)
  • ISO 9001 Quality Management System
  • ISO 22000 Food Safety Management System
  • HALAL Certification
  • IQNET (The International Certification Network)
  • Technical Dossier (Certificate of Analysis – COA, Technical Data Sheet – TDS, Material Safety Data Sheet – MSDS)

7. Recommended Synergistic Combinations

  • Adenosine + Peptides: Enhances anti-wrinkle and firming synergy.
  • Adenosine + Caffeine: Used in anti-hair loss products for combined stimulation.

8. Typical Applications & Success Stories

  • Product Categories: Hair Regrowth Tonics, Firming Eye Serums, Advanced Anti-Aging Creams, Scalp Vitalizing Shampoos.

9. Scientific Evidence & Literature Support

9.1 Clinical Hair Loss Trial (0.75% Adenosine Lotion)

  • Method: Volunteers with female hair loss were administered $0.75\%$ Adenosine lotion or placebo twice daily for 12 months.
  • Results: After 12 months, the Adenosine group showed a faster rate of growing hair and increased hair density compared to the control group, and hair felt denser.
    • Month 12 Investigator Assessments: 93% of the Adenosine group had $0$ or above improvement, compared to 64% in the placebo group.
    • Another 6-month trial: The Adenosine group’s anagen hair ratio and hair density were significantly higher than the placebo group.

9.2 Anti-Wrinkle Efficacy

  • Results: Skin care products containing Adenosine were shown to effectively increase stratum corneum water content, reduceTEWL, and improve crow’s feet, demonstrating anti-wrinkle efficacy.

10. Stability and Safety Data Summary

  • Safety Profile: Safe for use in personal care products.
  • Stability: The 98% powder grade guarantees a 24-month shelf life.

11. Frequently Asked Questions (FAQ)

Q1: What is the CAS number for Adenosine?

A: The CAS number is 58-61-7.

Q2: Is Adenosine water-soluble?

A: Yes, the $98\%$ powder grade is water-soluble.

Q3: What are the primary skin benefits?

A: Anti-wrinkle, firming, and improving skin moisture retention.

Q4: Is it clinically proven for hair loss?

A: Yes, clinical trials showed that $0.75\%$ Adenosine lotion resulted in a faster rate of hair growth and higher hair density in female hair loss over 12 months.

 

Source the Multi-Functional Adenosine for Clinically Supported Anti-Aging and Hair Loss Solutions.

🔒 Get Your Technical Dossier: Access TDS, MSDS, COA, and Clinical Efficacy Reports.

🔬 Apply for a Free Sample: Test the stable, high-efficacy cell-regulating power of Adenosine today.

📞 Get a Customized Quote: Discuss bulk orders and high-purity specifications.

Empower Your Skin Science: Develop Next-Generation Formulations with Our Premium Active Ingredients.

Huatai Bio provides a comprehensive portfolio of high-efficacy cosmetic active ingredients, empowering global brands to create next-generation skincare formulations for high-end skincare formulation needs.

Comprehensive Solutions & Innovation: Our categories cover the full spectrum of market requirements: Anti-aging & Firming, Oil-Control & Anti-acne, Anti-inflammatory & Soothing,Antioxidant Defense, Brightening,and Hydration & Barrier Repair.We offer both established classics and cutting-edge actives.

Driven by a passion for scientific excellence, our state-of-the-art R&D laboratory is dedicated to exploring the frontier of bio-active molecules. Beyond supplying ingredients, we offer end-to-end formulation consultancy and customized solution development. Our team of expert chemists works closely with your brand to overcome complex stability issues and sensory challenges, ensuring your final product stands out in a competitive global market.

Uncompromising Quality & Credibility:We ensure every batch of our Active skincare ingredients meets rigorous quality standards, including COSMOS, ISO 9001/22000, and HALAL Certification. This commitment, backed by a complete Technical Dossier, offers clinically-backed solutions and guaranteed compliance for every formulation challenge.

Laissez un message