{"id":7196,"date":"2025-12-01T09:05:18","date_gmt":"2025-12-01T09:05:18","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=7196"},"modified":"2026-07-15T02:38:46","modified_gmt":"2026-07-15T02:38:46","slug":"glycyrrhetinic-acid-for-skin-skin-soothing-and-anti-inflammatory-power","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ko\/glycyrrhetinic-acid-for-skin-skin-soothing-and-anti-inflammatory-power\/","title":{"rendered":"\ud53c\ubd80\ub97c \uc704\ud55c \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0: \ud53c\ubd80 \uc9c4\uc815 \ubc0f \ud56d\uc5fc \ud6a8\uacfc"},"content":{"rendered":"<p>\ub300\ubd80\ubd84\uc758 \ud654\uc7a5\ud488 \uc81c\ud615 \uc804\ubb38\uac00\ub294 \uadfc\ubcf8\uc801\uc778 \ubb38\uc81c\uc5d0 \uc9c1\uba74\ud569\ub2c8\ub2e4. \uc6b0\uc544\ud55c \uc5d0\uba40\uc83c\uc744 \ub9cc\ub4e4\uace0 \ud65c\uc131 \uc2dd\ubb3c \ucd94\ucd9c\ubb3c\uc744 \ucca8\uac00\ud574\ub3c4 \ubbfc\uac10\uc131 \ud53c\ubd80 \ud328\uce58 \ud14c\uc2a4\ud2b8\uc5d0 \uc2e4\ud328\ud569\ub2c8\ub2e4. \uc65c \uadf8\ub807\uac8c \ub9ce\uc740 \uc9c4\uc815 \uc81c\ud488\uc774 \uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c \uc2e4\ud328\ud560\uae4c\uc694? \ud45c\uba74\uc801\uc778 \uc99d\uc0c1\ub9cc \ub2e4\ub8e8\uace0 \uadfc\ubcf8\uc801\uc778 \ud6a8\uc18c \uacbd\ub85c\ub97c \ud45c\uc801\uc73c\ub85c \uc0bc\uc9c0 \uc54a\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. \ud53c\ubd80\uc758 \uc0dd\ubb3c\ud559\uc801 \uc5b8\uc5b4\ub97c \uc774\ud574\ud558\ub294 \ud65c\uc131 \uc131\ubd84\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0(Glycyrrhetinic Acid)\uc744 \uc18c\uac1c\ud569\ub2c8\ub2e4.<\/p><p>\uc9c0\uae08 \ub370\ub974\ubaa8\ucf54\uc2a4\uba54\ud2f1 \uc2dc\uc7a5\uc5d0\uc11c \uac70\ub300\ud55c \ubcc0\ud654\ub97c \ubaa9\uaca9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uacf5\uaca9\uc801\uc778 \ud544\ub9c1\uacfc \uace0\ub18d\ub3c4 \uc0b0(acid)\uc740 \uc774\uc81c \uc61b\ub9d0\uc785\ub2c8\ub2e4. \uc7a5\ubcbd \ubcf5\uad6c\uc640 \uae4a\uc740 \uc9c4\uc815\uc774 \ub300\uc138\uc785\ub2c8\ub2e4. \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ud65c\uc131 \uc131\ubd84 \uc804\ubb38 \uc81c\uc870\uc5c5\uccb4\ub85c\uc11c \uc6b0\ub9ac\ub294 \uc774\ub97c \uc9c1\uc811 \uacbd\ud5d8\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ube0c\ub79c\ub4dc\ub4e4\uc740 \ub354 \uc774\uc0c1 \uc77c\ubc18\uc801\uc778 \"\uac10\ucd08 \ucd94\ucd9c\ubb3c\"\uc744 \uc6d0\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc785\uc99d\ub41c \uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc744 \uac00\uc9c4 \ubd84\ub9ac\ub41c \uace0\uc21c\ub3c4 \ubd84\uc790\ub97c \uc694\uad6c\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \uc774\ub7ec\ud55c \uc694\uad6c\uc758 \uc815\uc810\uc744 \ub300\ud45c\ud569\ub2c8\ub2e4.<\/p><p>\ubd84\uc790 \uad6c\uc870: \uc5b4\ub5bb\uac8c \uc791\uc6a9\ud558\ub294\uac00?<\/p><p>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0(Glycyrrhetinic Acid)\uc740 \uc5d0\ub179\uc194\ub860(Enoxolone)\uc774\ub77c\uace0\ub3c4 \ud558\uba70, \uac10\ucd08(Glycyrrhiza glabra) \ubfcc\ub9ac\uc5d0\uc11c \uc720\ub798\ud55c \ud39c\ud0c0\uc0ac\uc774\ud074\ub9ad \ud2b8\ub9ac\ud14c\ub974\ud398\ub178\uc774\ub4dc\uc785\ub2c8\ub2e4. \uac10\ucd08 \ubfcc\ub9ac \uc18d\uc758 \uc5d4\uc9c4\uc774\ub77c\uace0 \uc0dd\uac01\ud558\uc2dc\uba74 \ub429\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub9ac\uc81c\uc774\ud2b8\uc774\uce7c\ub968(Dipotassium Glycyrrhizate)\uc740 \uc218\uc6a9\uc131\uc774\uba70 \ud1a0\ub108\uc5d0 \ub110\ub9ac \uc0ac\uc6a9\ub418\uc9c0\ub9cc, \uc21c\uc218 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \uc9c0\uc6a9\uc131\uc785\ub2c8\ub2e4. \uc774\ub294 \uc6b0\uc218\ud55c \ud45c\ud53c \uce68\ud22c \ub2a5\ub825\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uac01\uc9c8\uce35\uc744 \ub180\ub77c\uc6b4 \ud6a8\uc728\ub85c \ud1b5\uacfc\ud569\ub2c8\ub2e4.<\/p><p>\uc8fc\uc694 \uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc740 11\u03b2-\ud558\uc774\ub4dc\ub85d\uc2dc\uc2a4\ud14c\ub85c\uc774\ub4dc \ud0c8\uc218\uc18c\ud6a8\uc18c(11\u03b2-hydroxysteroid dehydrogenase, 11\u03b2-HSD)\uc758 \uc5b5\uc81c\uc5d0 \uc758\uc874\ud569\ub2c8\ub2e4. \uc774 \ud6a8\uc18c\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \ucf54\ub974\ud2f0\uc194\uc744 \ube44\ud65c\uc131 \ucf54\ub974\ud2f0\uc190\uc73c\ub85c \uc804\ud658\uc2dc\ucf1c \ube44\ud65c\uc131\ud654\ud569\ub2c8\ub2e4. \ucf54\ub974\ud2f0\uc194\uc740 \uc5fc\uc99d\uc5d0 \ub300\ud55c \ud53c\ubd80\uc758 \ucc9c\uc5f0 \uc18c\ud654\uae30 \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. 11\u03b2-HSD\ub97c \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \uc18c\ud654\uae30\uac00 \ub354 \uc624\ub798 \uc791\ub3d9\ud558\ub3c4\ub85d \uc720\uc9c0\ud569\ub2c8\ub2e4. \uad6d\uc18c \uc2a4\ud14c\ub85c\uc774\ub4dc \ub3c4\ud3ec\uc758 \ubd80\uc791\uc6a9 \uc5c6\uc774 \ud65c\uc131 \ucf54\ub974\ud2f0\uc194\uc758 \uad6d\uc18c \ub18d\ub3c4\uac00 \uc548\uc804\ud558\uac8c \uc99d\uac00\ud569\ub2c8\ub2e4. \uc774\ub294 \uae4a\uace0 \uc989\uac01\uc801\uc778 \uc9c4\uc815 \ud6a8\uacfc\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p><p>\uc2e4\uc81c \ub370\uc774\ud130: \uacfc\uc7a5 \uad11\uace0\ub97c \ub118\uc5b4\uc120 \ud6a8\ub2a5<\/p><p>\uc6b0\ub9ac\ub294 \uc774\ub860\uc801\uc778 \uc0dd\ud654\ud559\uc5d0\ub9cc \uc758\uc874\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc2e4\uc81c \uc81c\ud615\uc5d0\ub294 \uc6d0\uc2dc \ub370\uc774\ud130\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \ud6a8\ub2a5 \uac80\uc99d \uc911\uc5d0 \ucd94\uc801\ud558\ub294 \ud2b9\uc815 \uc131\ub2a5 \uc9c0\ud45c\ub97c \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.<\/p><p>\uc5fc\uc99d \ub9e4\uac1c\uccb4 \uc5b5\uc81c<\/p><p>\uc800\ud76c \uc5f0\uad6c\uc2e4\uc740 \ud65c\uc131 \uc131\ubd84\uc774 \ud53c\ubd80 \uc2a4\ud2b8\ub808\uc2a4\uc758 \uc8fc\uc694 \ud45c\uc9c0\uc790\ub97c \uc5b4\ub5bb\uac8c \uc5b5\uc81c\ud558\ub294\uc9c0\uc5d0 \uc911\uc810\uc744 \ub461\ub2c8\ub2e4. \uc778\uac04 \ud45c\ud53c \uac01\uc9c8 \uc138\ud3ec\uc5d0 \ub300\ud55c \ud1b5\uc81c\ub41c \uc2dc\ud5d8\uad00 \ub0b4 \uc5f0\uad6c\uc5d0\uc11c \uc138\ud3ec\ub294 UV \uc2a4\ud2b8\ub808\uc2a4\uc5d0 \ub178\ucd9c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud64d\ubc18\uacfc \ud1b5\uc99d\uc758 \uc8fc\uc694 \uc6d0\uc778\uc778 \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518 E2(Prostaglandin E2, PGE2)\uc758 \ubc29\ucd9c\uc744 \uce21\uc815\ud588\uc2b5\ub2c8\ub2e4.<\/p><p>1% \ub18d\ub3c4\uc758 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc73c\ub85c \ucc98\ub9ac\ud588\uc744 \ub54c, \ucc98\ub9ac\ud558\uc9c0 \uc54a\uc740 \ub300\uc870\uad70\uc5d0 \ube44\ud574 24\uc2dc\uac04 \uc774\ub0b4\uc5d0 PGE2 \uc218\uce58\uac00 \ud3c9\uade0 42% \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. 0.5%\uc758 \ub354 \ub192\uc740 \ub18d\ub3c4\uc5d0\uc11c\ub294 68% \uac10\uc18c\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc774 \ube44\uc120\ud615 \uc6a9\ub7c9-\ubc18\uc751 \uace1\uc120\uc740 \ub0ae\uc740 \ub18d\ub3c4\uc5d0\uc11c\ub3c4 \uc81c\ud615\uc5d0\uc11c \uc0c1\ub2f9\ud55c \ud6a8\uacfc\ub97c \ubc1c\ud718\ud568\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4. \uacb0\uacfc\ub97c \uc5bb\uae30 \uc704\ud574 \uc5d0\uba40\uc83c\uc744 \uacfc\ub3c4\ud558\uac8c \uc0ac\uc6a9\ud560 \ud544\uc694\uac00 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p><p>\uc784\uc0c1 \uc801\uc6a9: UV \uc720\ubc1c \ud64d\ubc18<\/p><p>\uc800\ud76c\ub294 \uc81c3\uc790 \ud14c\uc2a4\ud2b8 \uc2dc\uc124\uacfc \ud611\ub825\ud558\uc5ec \uc0dd\uccb4 \ub0b4 \uc9c4\uc815 \ub2a5\ub825\uc744 \uce21\uc815\ud588\uc2b5\ub2c8\ub2e4. 20\uba85\uc758 \uac74\uac15\ud55c \uc790\uc6d0\uc790\uc5d0\uac8c \ud45c\uc900 \ud64d\ubc18\uc744 \uc720\ubc1c\ud558\uae30 \uc704\ud574 \ud314\ub69d\uc5d0 \ud1b5\uc81c\ub41c UV \ubc29\uc0ac\uc120\uc744 \uc870\uc0ac\ud588\uc2b5\ub2c8\ub2e4. \ud55c\ucabd \ud314\uc5d0\ub294 0.2% \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc774 \ud568\uc720\ub41c \uae30\ubcf8 \uc5d0\uba40\uc83c\uc744, \ub2e4\ub978 \ucabd \ud314\uc5d0\ub294 \uc704\uc57d \uc5d0\uba40\uc83c\uc744 \ub3c4\ud3ec\ud588\uc2b5\ub2c8\ub2e4.<\/p><p>120\ubd84 \ud6c4, \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc73c\ub85c \ucc98\ub9ac\ub41c \ud53c\ubd80\ub294 \uc704\uc57d\uc5d0 \ube44\ud574 \ubd84\uad11\uad11\ub3c4\uacc4\ub85c \uce21\uc815\ud55c \ubd89\uc740 \uae30 \uac10\uc18c \uc18d\ub3c4\uac00 38% \ube68\ub790\uc2b5\ub2c8\ub2e4. \uc790\uc6d0\uc790\ub4e4\uc758 \uc8fc\uad00\uc801\uc778 \ud53c\ub4dc\ubc31 \ub610\ud55c \uc989\uac01\uc801\uc778 \uc2dc\uc6d0\ud568\uacfc \ud3b8\uc548\ud568\uc744 \uac15\uc870\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uc911\uc694\ud55c \uc18c\ube44\uc790 \uc811\uc810\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/p><p>\uc0ac\uc591 \ubc0f \ud488\uc9c8 \ubca4\uce58\ub9c8\ud06c<\/p><p>\ubaa8\ub4e0 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc774 \ub3d9\uc77c\ud558\uac8c \ub9cc\ub4e4\uc5b4\uc9c0\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4. \ucd94\ucd9c \uacf5\uc815\uc740 \uc21c\ub3c4, \uc0c9\uc0c1, \uadf8\ub9ac\uace0 \uad81\uadf9\uc801\uc73c\ub85c \uc81c\ud615\uc5d0\uc11c\uc758 \uc131\ub2a5\uc744 \uacb0\uc815\ud569\ub2c8\ub2e4. \ubd88\uc21c\ubb3c\uc774 \ub9ce\uc740 \ubc30\uce58\ub294 \uc885\uc885 \uac15\ud55c \ub0c4\uc0c8\uc640 \uc5b4\ub450\uc6b4 \ub178\ub780\uc0c9\uc744 \ub760\uc5b4 \uc2dc\uac04\uc774 \uc9c0\ub0a8\uc5d0 \ub530\ub77c \ud770\uc0c9 \ud06c\ub9bc\uc758 \uc0c9\uc0c1\uc744 \ubd88\uc548\uc815\ud558\uac8c \ub9cc\ub4ed\ub2c8\ub2e4. \uc8fc\uc694 \uc81c\uc870\uc5c5\uccb4\ub85c\uc11c Shaanxi Huatai\ub294 \uc774\ub7ec\ud55c \ub9e4\uac1c\ubcc0\uc218\ub97c \uc5c4\uaca9\ud558\uac8c \uc81c\uc5b4\ud569\ub2c8\ub2e4. \ub2e4\uc74c\uc740 \ub2f9\uc0ac\uc758 \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ub4f1\uae09\uc5d0 \ub300\ud55c \ud45c\uc900 \ubd84\uc11d\uc785\ub2c8\ub2e4.<\/p><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><td><strong>\ub9e4\uac1c\ubcc0\uc218<\/strong><\/td><td><strong>\uc0ac\uc591 \ubca4\uce58\ub9c8\ud06c<\/strong><\/td><td><strong>\ubd84\uc11d \ubc29\ubc95<\/strong><\/td><\/tr><\/thead><tbody><tr><td>\ubaa8\uc2b5<\/td><td>\ud770\uc0c9 \ub610\ub294 \ubbf8\uc0c9\uc758 \uacb0\uc815\uc131 \ubd84\ub9d0<\/td><td>Visual Inspection<\/td><\/tr><tr><td>\ubd84\uc11d (\uc21c\ub3c4)<\/td><td>\u2265 98.0%<\/td><td>HPLC<\/td><\/tr><tr><td>CAS \ubc88\ud638<\/td><td>471-53-4<\/td><td>\ud574\ub2f9 \uc5c6\uc74c<\/td><\/tr><tr><td>\ub179\ub294\uc810<\/td><td>292\u00b0C \u2013 296\u00b0C<\/td><td>\uc735\uc810 \uce21\uc815\uae30<\/td><\/tr><tr><td>\uac74\uc870 \uac10\ub7c9<\/td><td>\u2264 1.0%<\/td><td>105\u00b0C, 2\uc2dc\uac04<\/td><\/tr><tr><td>Heavy Metals (Pb)<\/td><td>10ppm \uc774\ud558<\/td><td>\uc6d0\uc790 \ud761\uc218 \ubd84\uad11\ubc95<\/td><\/tr><tr><td>\uc6a9\ud574\ub3c4<\/td><td>\ubb3c\uc5d0 \ubd88\uc6a9\uc131, \uc5d0\ud0c4\uc62c\/\uae00\ub9ac\ucf5c\uc5d0 \uc6a9\ud574<\/td><td>\uc57d\uc804 \ubc29\ubc95<\/td><\/tr><\/tbody><\/table><\/figure><p>\uc81c\ud615 \uad6c\uc870: \ubaa8\ubc94 \uc0ac\ub840<\/p><p>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc744 \ub2e4\ub8e8\ub824\uba74 \ud2b9\uc815 \uc811\uadfc \ubc29\uc2dd\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uc9c0\uc6a9\uc131\uc774 \ub9e4\uc6b0 \ub192\uae30 \ub54c\ubb38\uc5d0(\uae30\ub984\uc5d0 \uc6a9\ud574\ub428) \ub2e8\uc21c\ud788 \uc218\uc131 \uc0c1\uc5d0 \ub123\uc73c\uba74 \uc2e4\ud328\uac00 \ubcf4\uc7a5\ub429\ub2c8\ub2e4. \uc7ac\uacb0\uc815\ub418\uc5b4 \uac70\uce5c \uc9c8\uac10\uc744 \uc0dd\uc131\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p><p>\uc0ac\uc804 \ubd84\uc0b0\uc774 \ud544\uc218\uc801\uc785\ub2c8\ub2e4. \uc8fc\uc720\uc0c1\uc5d0 \ub3c4\uc785\ud558\uae30 \uc804\uc5d0 \uae00\ub9ac\ucf5c\uc774\ub098 \ucc9c\uc5f0 \uc624\uc77c\uc5d0 \uc6a9\ud574\ud558\ub294 \uac83\uc774 \uc88b\uc2b5\ub2c8\ub2e4. \uc5d0\ud1a1\uc2dc\ub514\uae00\ub9ac\ucf5c \ub610\ub294 \ud504\ub85c\ud310\ub514\uc62c\uc744 \ubd80\ub4dc\ub7ec\uc6b4 \uc5f4(\uc57d 60\u00b0C)\uacfc \ud63c\ud569\ud558\uba74 \uc644\uc804\ud55c \uc6a9\ud574\uac00 \ubcf4\uc7a5\ub429\ub2c8\ub2e4. \uc6a9\ud574\ub418\uba74 \uc5d0\uba40\uc83c pH\ub97c 4.0\uc5d0\uc11c 7.0 \uc0ac\uc774\ub85c \uc720\uc9c0\ud558\uc2ed\uc2dc\uc624. \uadf9\ub2e8\uc801\uc778 pH \uc218\uc900\uc740 \ud2b9\uc815 \ud3f4\ub9ac\uba38 \uae30\ubc18 \uc99d\uc810\uc81c\uc5d0\uc11c \ubd84\ud574 \ub610\ub294 \uc608\uc0c1\uce58 \ubabb\ud55c \uc810\ub3c4 \uac10\uc18c\ub97c \uc720\ubc1c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p><p>\uc81c\ud615 \ud301: \uc5d0\uba40\uc83c\uc774 \uce74\ubcf4\uba38\uc5d0 \ud06c\uac8c \uc758\uc874\ud558\ub294 \uacbd\uc6b0, \uce74\ubcf4\uba38\ub97c \uba3c\uc800 \uc911\ud654\ud55c \ub2e4\uc74c \ud65c\uc131 \uc720\uc0c1\uc744 \ub3c4\uc785\ud558\uc2ed\uc2dc\uc624. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc774 \uade0\uc9c8\ud654 \uacfc\uc815 \ucd08\uae30\uc5d0 \ub108\ubb34 \uc77c\ucc0d \ub3c4\uc785\ub418\uba74 \uc911\ud654\ub418\uc9c0 \uc54a\uc740 \uce74\ubcf4\uba38\uac00 \uce68\uc804\ub418\ub294 \uac83\uc744 \ubcf4\uc558\uc2b5\ub2c8\ub2e4.<\/p><p>\uc2dc\ub108\uc9c0: \uace0\uae09 \uc9c4\uc815 \uc2dc\uc2a4\ud15c \uad6c\ucd95<\/p><p>\ud604\ub300 \uc2a4\ud0a8\ucf00\uc5b4\ub294 \ub2e8\uc77c \ud575\uc2ec \uc131\ubd84\uc5d0 \uc758\uc874\ud558\ub294 \uacbd\uc6b0\uac00 \ub4dc\ubb45\ub2c8\ub2e4. \uc2dc\ub108\uc9c0\uac00 \uc9c4\uc815\ud55c \uc784\uc0c1 \uacb0\uacfc\ub97c \uc774\ub04c\uc5b4\ub0c5\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \ud65c\uc131 \uc131\ubd84\ub4e4\uc774 \ud568\uaed8 \uc5b4\ub5bb\uac8c \uc791\uc6a9\ud558\ub294\uc9c0 \ub04a\uc784\uc5c6\uc774 \ud14c\uc2a4\ud2b8\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uacfc \ub2e4\ub978 \uc785\uc99d\ub41c \ubd84\uc790\ub97c \uacb0\ud569\ud558\uba74 \uc2ec\uac01\ud55c \ud53c\ubd80 \uc7a5\ubcbd \uc190\uc0c1\uc744 \uc704\ud55c \ud45c\uc801 \uc194\ub8e8\uc158\uc744 \ub9cc\ub4e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p><ul class=\"wp-block-list\"><li>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0 + \ud1a0\ud0c0\ub864(Totarol): \uc5ec\ub4dc\ub984\uc131 \ud53c\ubd80\uc5d0 \uc808\ub300\uc801\uc778 \ud6a8\ub2a5\uc744 \ubc1c\ud718\ud569\ub2c8\ub2e4. \ud1a0\ud0c0\ub864\uc740 C. acnes\uc5d0 \ub300\ud55c \uac15\ub825\ud55c \ud56d\uade0 \uc791\uc6a9\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \ud65c\uc131 \uc5ec\ub4dc\ub984\uacfc \uad00\ub828\ub41c \uc2ec\uac01\ud55c \uc5fc\uc99d\uc744 \uc911\ud654\ud569\ub2c8\ub2e4. \uc774 \uc870\ud569\uc740 \uacfc\uc0b0\ud654\ubca4\uc870\uc77c\uc758 \uac74\uc870 \ud6a8\uacfc \uc5c6\uc774 \uac10\uc5fc\uacfc \ubd89\uc740 \uae30\ub97c \ub3d9\uc2dc\uc5d0 \uce58\ub8cc\ud569\ub2c8\ub2e4.<\/li>\n\n<li>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0 + \ub9ac\ucf54\uce7c\ucf58 A(Licochalcone A): \ubbfc\uac10\uc131 \ud53c\ubd80\ub97c \uc704\ud55c \uad81\uadf9\uc801\uc778 \uc194\ub8e8\uc158\uc785\ub2c8\ub2e4. \ub9ac\ucf54\uce7c\ucf58 A\ub294 \uc5fc\uc99d \uc720\ubc1c \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \uc989\uc2dc \ud558\ud5a5 \uc870\uc808\ud558\ub294 \ub370 \ud0c1\uc6d4\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \uc9c0\uc18d\uc801\uc778 \ucf54\ub974\ud2f0\uc194 \ubcf4\uc874 \ud6a8\uacfc\ub97c \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774 \ub450 \uac00\uc9c0\ub294 \ube60\ub974\uace0 \uc624\ub798 \uc9c0\uc18d\ub418\ub294 \uc7a5\ubcbd \ubc29\uc5b4 \uae30\ub2a5\uc744 \ub9cc\ub4ed\ub2c8\ub2e4.<\/li>\n\n<li>Glycyrrhetinic Acid + Glabridin: \uacfc\uc0c9\uc18c \uce68\ucc29 \ud6c4 \uad00\ub9ac\uc5d0 \uc644\ubcbd\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \uba5c\ub77c\ub2cc \uc138\ud3ec\uac00 \uc0c9\uc18c\ub97c \uacfc\ub3c4\ud558\uac8c \uc0dd\uc131\ud558\uac8c \ud558\ub294 \uc5fc\uc99d \uc720\ubc1c \uc694\uc778\uc744 \ucc28\ub2e8\ud569\ub2c8\ub2e4. \uadf8\ub7f0 \ub2e4\uc74c \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c\ub97c \uc9c1\uc811 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \ud558\ub098\uc758 \uc6b0\uc544\ud55c \uc2dc\uc2a4\ud15c\uc73c\ub85c \uc9c4\uc815 \ubc0f \ubbf8\ubc31 \ud6a8\uacfc\ub97c \uc5bb\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/li><\/ul><p>\uc2e4\uc81c \uc0ac\ub840 \uc5f0\uad6c<\/p><p>\ucd5c\uadfc \ud55c \uc720\ub7fd \ub354\ubaa8\ucf54\uc2a4\uba54\ud2f1 \ube0c\ub79c\ub4dc\ub294 \uc8fc\ub825 \ub85c\uc0ac\uc2dc\uc544 \uad00\ub9ac \ud06c\ub9bc\uc744 \ub9ac\ub274\uc5bc\ud588\uc2b5\ub2c8\ub2e4. \uc774\uc804 \uc81c\ud615\uc740 \uc77c\ubc18\uc801\uc778 \uc2dd\ubb3c \ucd94\ucd9c\ubb3c \ud63c\ud569\ubb3c\uc5d0 \ud06c\uac8c \uc758\uc874\ud588\uc73c\uba70 \ubc30\uce58 \uac04 \uc77c\uad00\uc131\uc5d0 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uc815\ub7c9\ud654 \uac00\ub2a5\ud55c \ud65c\uc131 \uc131\ubd84\uc744 \uc6d0\ud588\uc2b5\ub2c8\ub2e4.<\/p><p>\uadf8\ub4e4\uc740 98% \uc21c\uc218 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc744 \ub77c\uba5c\ub77c \uc561\uc815 \uc5d0\uba40\uc804\uc5d0 0.3% \ud1b5\ud569\ud588\uc2b5\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \uc911\uae08\uc18d\uc774 2ppm \ubbf8\ub9cc\uc784\uc744 \ubcf4\uc5ec\uc8fc\ub294 \uad11\ubc94\uc704\ud55c COA \ub370\uc774\ud130\ub97c \uc81c\uacf5\ud558\uc5ec \uc190\uc0c1\ub41c \ud53c\ubd80\uc5d0 \ub300\ud55c \ucd5c\ub300 \uc548\uc804\uc131\uc744 \ubcf4\uc7a5\ud588\uc2b5\ub2c8\ub2e4. \uacbd\uc99d\uc5d0\uc11c \uc911\ub4f1\ub3c4\uc758 \ub85c\uc0ac\uc2dc\uc544\ub85c \uace0\ud1b5\ubc1b\ub294 40\uba85\uc758 \ucc38\uac00\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c 8\uc8fc\uac04\uc758 \uc784\uc0c1 \uc2dc\ud5d8 \ud6c4, \ube0c\ub79c\ub4dc\ub294 \uae30\uc900 \ud64d\ubc18\uc774 52% \uac10\uc18c\ud588\ub2e4\uace0 \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \ub354 \uc911\uc694\ud55c \uac83\uc740, \uc81c\ud488\uc774 \ub354 \uc774\uc0c1 \uc801\uc6a9 \uc2dc \ub530\uac11\uc9c0 \uc54a\uc558\uae30 \ub54c\ubb38\uc5d0 \uc18c\ube44\uc790 \uc21c\uc751\ub3c4\uac00 \uc99d\uac00\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 5\uac00\uc9c0 \ub0ae\uc740 \ud6a8\ub2a5\uc758 \ucd94\ucd9c\ubb3c\uc744 \ud558\ub098\uc758 \uace0\uc21c\ub3c4 \ud65c\uc131 \uc131\ubd84\uc73c\ub85c \ub300\uccb4\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uacf5\uae09\ub9dd\uc744 \uac04\uc18c\ud654\ud558\uace0 \uc804\uccb4 \uc81c\ud615 \ube44\uc6a9\uc744 12% \uc808\uac10\ud588\uc2b5\ub2c8\ub2e4.<\/p><p>\ubd84\uc11d \uc99d\uba85\uc11c(COA) \uc77d\uae30<\/p><p>\ud22c\uba85\uc131\uc774 \uc911\uc694\ud569\ub2c8\ub2e4. \ud65c\uc131 \uc131\ubd84\uc744 \uc18c\uc2f1\ud560 \ub54c COA\ub294 \ubc95\uc801 \ubc0f \uae30\uc220\uc801 \ubcf4\ud638 \uc7a5\uce58\uc785\ub2c8\ub2e4. \ud2b9\uc815 HPLC \ud06c\ub85c\ub9c8\ud1a0\uadf8\ub7a8 \ucc38\uc870\uac00 \ub204\ub77d\ub41c COA\ub294 \uc218\ub77d\ud558\uc9c0 \ub9c8\uc2ed\uc2dc\uc624. \uc815\ud655\ud55c \ubd84\uc11d \ube44\uc728\uc744 \ud655\uc778\ud574\uc57c \ud569\ub2c8\ub2e4. \"\u2265 90%\"\ub85c \ud45c\uc2dc\ub41c COA\ub294 \uc5d0\uba40\uc804\uc744 \ubd88\uc548\uc815\ud558\uac8c \ub9cc\ub4e4 \uc218 \uc788\ub294 \ube44\ud65c\uc131 \uc2dd\ubb3c \uc641\uc2a4\uc5d0 \ub108\ubb34 \ub9ce\uc740 \uc5ec\uc9c0\ub97c \ub0a8\uae41\ub2c8\ub2e4.<\/p><p>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc5d0 \ub300\ud55c \ub2f9\uc0ac\uc758 \ud45c\uc900 COA\uc5d0\ub294 \ud56d\uc0c1 \ubbf8\uc0dd\ubb3c \ud55c\ub3c4(\ucd1d \uade0\uc218 \u2264 1000 cfu\/g, \ud6a8\ubaa8 \ubc0f \uacf0\ud321\uc774 \u2264 100 cfu\/g)\uac00 \ud3ec\ud568\ub418\uba70 E. coli \ubc0f Salmonella\uc640 \uac19\uc740 \ubcd1\uc6d0\uade0\uc758 \ubd80\uc7ac\ub97c \uc5c4\uaca9\ud558\uac8c \ud14c\uc2a4\ud2b8\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc5c4\uaca9\ud55c \uc900\uc218\ub294 \ucd5c\uc885 \uc81c\ud488 \ubbf8\uc0dd\ubb3c \ub3c4\uc804 \ud14c\uc2a4\ud2b8\ub97c \uc27d\uac8c \ud1b5\uacfc\ud558\ub3c4\ub85d \ubcf4\uc7a5\ud569\ub2c8\ub2e4.<\/p><p>\uc0b0\uc5c5 \ub3d9\ud5a5 \ubc0f \uaddc\uc815 \uc900\uc218<\/p><p>\uaddc\uc81c \ud658\uacbd\uc774 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uac15\ud654\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubbf8\uad6d\uc758 MoCRA\uc640 EU\uc758 \ub354 \uc5c4\uaca9\ud55c \uc548\uc804\uc131 \ud3c9\uac00\ub294 \uc81c\ud615 \ub2f4\ub2f9\uc790\uac00 \ubaa8\ub4e0 \uc131\ubd84\uc744 \uc815\ub2f9\ud654\ud558\ub3c4\ub85d \uc694\uad6c\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \ub9e4\uc6b0 \uc720\ub9ac\ud55c \uaddc\uc81c \uc0c1\ud0dc\ub97c \ub204\ub9ac\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc804 \uc138\uacc4\uc801\uc73c\ub85c \ud654\uc7a5\ud488 \uc0ac\uc6a9\uc774 \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud654\uc7a5\ud488 \uc131\ubd84 \uac80\ud1a0(CIR) \uc804\ubb38\uac00 \ud328\ub110\uc774 \uc774\ub97c \ud3c9\uac00\ud588\uc73c\uba70 \ud604\uc7ac \uad00\ud589 \ubc0f \ub18d\ub3c4\uc5d0\uc11c \uc0ac\uc6a9\ud558\uae30\uc5d0 \uc548\uc804\ud558\ub2e4\uace0 \ud310\ub2e8\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uae00\ub85c\ubc8c \uaddc\uc815 \uc900\uc218\ub294 \uc5ec\ub7ec \ub300\ub959\uc5d0 \uac78\uccd0 \uc7ac\ud615\uc131 \uc5c6\uc774 \uc218\ucd9c\ud558\ub824\ub294 \ube0c\ub79c\ub4dc\uc5d0\uac8c \uc774\uc0c1\uc801\uc778 \uc120\ud0dd\uc785\ub2c8\ub2e4.<\/p><p>\uc81c\ud615 \uccad\uc0ac\uc9c4: \ub808\uc2a4\ud050 \ubc24<\/p><p>\uc989\uc2dc \uc2dc\uc791\ud560 \uc218 \uc788\ub3c4\ub85d \uc9d1\uc911\uc801\uc778 \uc7a5\ubcbd \ubcf5\uad6c \ubc24\uc5d0 \ub300\ud55c \uae30\ubcf8 \uc544\ud0a4\ud14d\ucc98 \uc81c\uc548\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4.<\/p><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><td><strong>\uc0c1<\/strong><\/td><td><strong>Ingredient<\/strong><\/td><td><strong>\ube44\uc728 (%)<\/strong><\/td><td><strong>\uae30\ub2a5<\/strong><\/td><\/tr><\/thead><tbody><tr><td>\uc5d0\uc774<\/td><td>Water (Aqua)<\/td><td>Q.S. 100\uae4c\uc9c0<\/td><td>Solvent<\/td><\/tr><tr><td>\uc5d0\uc774<\/td><td>\uae00\ub9ac\uc138\ub9b0<\/td><td>4.00<\/td><td>\ubcf4\uc2b5\uc81c<\/td><\/tr><tr><td>\ube44<\/td><td>Caprylic\/Capric Triglyceride<\/td><td>12.00<\/td><td>\uc5f0\ud654\uc81c<\/td><\/tr><tr><td>\ube44<\/td><td>\uc138\ud14c\uc544\ub9b4 \uc54c\ucf54\uc62c &amp; \uc138\ud14c\uc544\ub9b4 \uae00\ub8e8\ucf54\uc0ac\uc774\ub4dc<\/td><td>4.50<\/td><td>\uc720\ud654\uc81c<\/td><\/tr><tr><td>\ube44<\/td><td>\uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0 (98%)<\/td><td>0.40<\/td><td>\ud65c\uc131 \uc9c4\uc815<\/td><\/tr><tr><td>\ube44<\/td><td>\uc2a4\ucfe0\uc54c\ub780<\/td><td>3.00<\/td><td>\uc7a5\ubcbd \ubcf4\uc218<\/td><\/tr><tr><td>\uae30\uc74c<\/td><td>\uc608\ubc29\ubc95<\/td><td>1.00<\/td><td>\ubcf4\ud638<\/td><\/tr><\/tbody><\/table><\/figure><p>\uc808\ucc28: \uc0c1 A\uc640 \uc0c1 B\ub97c \uac01\uac01 75\u00b0C\ub85c \uac00\uc5f4\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc774 \uc0c1 B\uc5d0 \uc644\uc804\ud788 \uc6a9\ud574\ub418\uc5c8\ub294\uc9c0 \ud655\uc778\ud569\ub2c8\ub2e4. \uace0\uc804\ub2e8 \ud558\uc5d0\uc11c \uc0c1 B\ub97c \uc0c1 A\ub85c \uc720\ud654\ud569\ub2c8\ub2e4. 40\u00b0C\ub85c \ub0c9\uac01\ud558\uace0 \uc0c1 C\ub97c \ucd94\uac00\ud569\ub2c8\ub2e4. pH\ub97c 5.5\ub85c \uc870\uc815\ud569\ub2c8\ub2e4.<\/p><p>\ud65c\uc131 \uc131\ubd84\uc744 \uc120\ud0dd\ud558\ub294 \uac83\uc740 \ub9c8\ucf00\ud305 \ube0c\ub85c\uc154\ub97c \uc77d\ub294 \uac83 \uc774\uc0c1\uc785\ub2c8\ub2e4. \uc0dd\ubb3c\ud559\uc801 \ud0c0\ub2f9\uc131, \uc5c4\uaca9\ud55c \uc21c\ub3c4 \ud45c\uc900 \ubc0f \uc2e0\ub8b0\ud560 \uc218 \uc788\ub294 \uacf5\uae09\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0\uc740 \ubaa8\ub4e0 \uba74\uc5d0\uc11c \uc81c\uacf5\ub429\ub2c8\ub2e4. \ud6a8\uc18c \uc218\uc900\uc5d0\uc11c \uc5fc\uc99d\uc744 \ucc28\ub2e8\ud569\ub2c8\ub2e4. \uce21\uc815 \uac00\ub2a5\ud55c \uc784\uc0c1\uc801 \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc62c\ubc14\ub974\uac8c \ucde8\uae09\ud558\uba74 \uae68\ub057\ud558\uac8c \uc81c\ud615\ud654\ub429\ub2c8\ub2e4.<\/p><p>\ub2f9\uc0ac\ub294 \uadc0\uc0ac\uc758 \ucc28\uc138\ub300 \uae30\ub2a5\uc131 \uc2a4\ud0a8\ucf00\uc5b4 \uc81c\ud488\uc744 \uc2dc\uc7a5\uc5d0 \ucd9c\uc2dc\ud558\ub294 \ub370 \ud544\uc694\ud55c \uae30\uc220 \uc790\ub8cc, \uace0\uc21c\ub3c4 \uc7ac\ub8cc \ubc0f \uc751\uc6a9 \uc9c0\uc6d0\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc5c4\uaca9\ud55c \uc2e4\ud5d8\uc2e4 \ud14c\uc2a4\ud2b8\ub85c \uc0ac\uc591\uc744 \ubcf4\uc99d\ud569\ub2c8\ub2e4. R&amp;D \uc2dc\ud5d8\uc744 \uc704\ud55c \uc0d8\ud50c\uc740 \uc694\uccad \uc2dc \uc81c\uacf5\ub429\ub2c8\ub2e4.<\/p><p>\ucc38\uace0 \ubb38\ud5cc \ubc0f \uc778\uc6a9\ub41c \uacf5\uac1c \ubb38\ud5cc:<\/p><ol start=\"1\" class=\"wp-block-list\"><li>\ud654\uc7a5\ud488 \uc131\ubd84 \uac80\ud1a0(CIR) \uc804\ubb38\uac00 \ud328\ub110. (2007). \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0, \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0 \uce7c\ub968, \uae00\ub9ac\uc2dc\ub974\ud788\uc9c4\uc0b0 \ub514\uce7c\ub968, \uae00\ub9ac\uc2dc\ub974\ud788\uc9c4\uc0b0 \uc554\ubaa8\ub284\uc758 \uc548\uc804\uc131 \ud3c9\uac00 \ucd5c\uc885 \ubcf4\uace0\uc11c. \uad6d\uc81c \ub3c5\uc131\ud559 \uc800\ub110.<\/li>\n\n<li>Kowalska, A. \ub4f1. (2019). \uac10\ucd08 \ubfcc\ub9ac \ucd94\ucd9c\ubb3c: \ud56d\uc5fc \ubc0f \ubbf8\ubc31 \ud654\ud569\ubb3c\uc758 \uacf5\uae09\uc6d0. \ud53c\ubd80\uacfc \uacfc\ud559 \uc800\ub110.<\/li>\n\n<li>\uc720\ub7fd \uc704\uc6d0\ud68c \ud654\uc7a5\ud488 \ubb3c\uc9c8 \ubc0f \uc131\ubd84 \ub370\uc774\ud130\ubca0\uc774\uc2a4(CosIng) \u2013 \uae00\ub9ac\uc2dc\ub808\ud2f4\uc0b0 \uaddc\uc81c \uc0c1\ud0dc.<\/li><\/ol>","protected":false},"excerpt":{"rendered":"<p>Most cosmetic formulators struggle with a fundamental problem. 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