{"id":14290,"date":"2026-06-29T05:56:15","date_gmt":"2026-06-29T05:56:15","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=14290"},"modified":"2026-06-29T06:03:06","modified_gmt":"2026-06-29T06:03:06","slug":"post-acne-pih-repair-combining-glabridin-and-totarol","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ko\/post-acne-pih-repair-combining-glabridin-and-totarol\/","title":{"rendered":"\uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c \uce68\ucc29(PIH) \uac1c\uc120: \uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud1a0\ud0c0\ub864\uc758 \uc870\ud569"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14290\" class=\"elementor elementor-14290\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a055c34 e-flex e-con-boxed e-con e-parent\" data-id=\"a055c34\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-545ba27 elementor-widget elementor-widget-html\" data-id=\"545ba27\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t  <script type=\"application\/ld+json\">{\n    \"@context\": \"https:\\\/\\\/schema.org\",\n    \"@type\": \"Article\",\n    \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\\\/\\\/glabridinchina.com\\\/post-acne-pih-repair-combining-glabridin-and-totarol\\\/\"\n    },\n    \"headline\": \"Post-Acne PIH Repair: Combining Glabridin and Totarol for Comprehensive Acne Aftermath Treatment\",\n    \"about\": [\n        {\n            \"@type\": \"ChemicalSubstance\",\n            \"name\": \"Glabridin\",\n            \"alternateName\": \"\\u5149\\u7518\\u8349\\u5b9a\"\n        },\n        {\n            \"@type\": \"ChemicalSubstance\",\n            \"name\": \"Totarol\",\n            \"alternateName\": \"\\u603b\\u6897\\u8d64\\u677e\\u7d20\"\n        }\n    ],\n    \"publisher\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical\",\n        \"url\": \"https:\\\/\\\/glabridinchina.com\"\n    },\n    \"author\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical Technical Team\"\n    },\n    \"datePublished\": \"2026\",\n    \"description\": \"A technical guide to formulating post-acne PIH repair products using glabridin and Totarol \\u2014 covering the PIH cycle mechanism, dual-active system design, complementary actives, and formulation blueprints.\"\n}<\/script>\n\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n  <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;500;600;700&family=Merriweather:ital,wght@0,400;0,700;1,400&display=swap\" rel=\"stylesheet\">\n\n  <style>\n    :root {\n      --color-bg:           #f9f9f7;\n      --color-surface:      #ffffff;\n      --color-border:       #e5e2d9;\n      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padding-left: 18px; }\n    .references li { font-size: 13px; color: var(--color-text-muted); line-height: 1.6; margin-bottom: 7px; }\n\n    .article-footer { margin-top: 36px; padding-top: 18px; border-top: 1px solid var(--color-border); font-size: 12px; color: var(--color-text-muted); line-height: 1.6; }\n  <\/style>\n<\/head>\n<body>\n\n\n  <div class=\"page-wrap\">\n\n    <header class=\"article-header\">\n      <div class=\"tag-row\">\n        <span class=\"tag\">\uc560\ud50c\ub9ac\ucf00\uc774\uc158<\/span>\n        <span class=\"tag secondary\">\uae00\ub77c\ube0c\ub9ac\ub518<\/span>\n        <span class=\"tag secondary\">\ud1a0\ud0c0\ub864<\/span>\n        <span class=\"tag secondary\">\uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29 (PIH)<\/span>\n      <\/div>\n\n      <p class=\"article-intro\">\uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29\uc740 UV \uc720\ubc1c \ubc18\uc810 \ubc0f \uae30\ubbf8\uc640\ub294 \ub2e4\ub978 \ubcd1\ub9ac\ud559\uc801 \uc694\uc778\uc744 \uac00\uc9c4 \uc5fc\uc99d \ud6c4 \uacfc\uc0c9\uc18c\uce68\ucc29(PIH)\uc758 \ud55c \ud615\ud0dc\uc785\ub2c8\ub2e4. \uc0c1\uc704 \uc5fc\uc99d\uc744 \ud574\uacb0\ud558\uc9c0 \uc54a\uace0 \uae30\uc874 \uc0c9\uc18c\uce68\ucc29\ub9cc\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc81c\ud615\uc740 \uc7ac\ubc1c\uc131 PIH \uc608\ubc29\uc5d0 \ub35c \ud6a8\uacfc\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud1a0\ud0c0\ub864\uc740 \uc0c1\ud638 \ubcf4\uc644\uc801\uc778 \uacbd\ub85c\ub97c \ud1b5\ud574 \uc774 \ubb38\uc81c\ub97c \ud574\uacb0\ud569\ub2c8\ub2e4. \ud558\ub098\ub294 \uc5ec\ub4dc\ub984 \ubcd1\ubcc0\uacfc \uad00\ub828\ub41c \ubbf8\uc0dd\ubb3c \ubc0f \uc5fc\uc99d \uc694\uc778\uc744 \ud45c\uc801\uc73c\ub85c \ud558\uace0, \ub2e4\ub978 \ud558\ub098\ub294 PIH \ud615\uc131\uc5d0 \uad00\uc5ec\ud558\ub294 \uc5fc\uc99d \ubc0f \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc18\uc751\uc744 \uc870\uc808\ud569\ub2c8\ub2e4.<\/p>\n      <div class=\"byline\">\n        <span><strong>\ud654\ud0dc \ubc14\uc774\uc624-\ud30c\uc778 \ucf00\ubbf8\uce7c<\/strong> \u2014 2008\ub144\ubd80\ud130 \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ud65c\uc131 \uc131\ubd84 \uc81c\uc870\uc5c5\uccb4 \u00b7 \ud1a0\ud0c0\ub864 \uc911\uad6d \ubcf8\ud1a0 \ub3c5\uc810 \uc720\ud1b5\uc5c5\uccb4<\/span>\n        <span style=\"color:var(--color-border)\">\u00b7<\/span>\n        <span>2026\ub144 \ubc1c\ud589<\/span>\n      <\/div>\n    <\/header>\n\n    <article class=\"article-body\">\n\n      <p>\uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29\uc740 UV \uc720\ubc1c \ubc18\uc810 \ubc0f \uae30\ubbf8\uc640\ub294 \ub2e4\ub978 \ubcd1\ub9ac\ud559\uc801 \uc694\uc778\uc744 \uac00\uc9c4 \uc5fc\uc99d \ud6c4 \uacfc\uc0c9\uc18c\uce68\ucc29(PIH)\uc758 \ud55c \ud615\ud0dc\uc785\ub2c8\ub2e4. \ubb38\uc81c\ub294 \uc794\uc5ec \uc0c9\uc18c\uce68\ucc29\ubfd0\ub9cc \uc544\ub2c8\ub77c \uba5c\ub77c\ub2cc \uc0dd\uc131\uc744 \uc720\ubc1c\ud558\ub294 \uc5ec\ub4dc\ub984 \ubcd1\ubcc0\uacfc \uad00\ub828\ub41c \uadfc\ubcf8\uc801\uc778 \uc5fc\uc99d \uacfc\uc815\uc785\ub2c8\ub2e4. \uc0c1\uc704 \uc5fc\uc99d\uc744 \ud574\uacb0\ud558\uc9c0 \uc54a\uace0 \uae30\uc874 \uc0c9\uc18c\uce68\ucc29\ub9cc\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc81c\ud615\uc740 \uc7ac\ubc1c\uc131 PIH \uc608\ubc29\uc5d0 \ub35c \ud6a8\uacfc\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud1a0\ud0c0\ub864\uc740 \uc0c1\ud638 \ubcf4\uc644\uc801\uc778 \uacbd\ub85c\ub97c \ud1b5\ud574 \uc774 \ubb38\uc81c\ub97c \ud574\uacb0\ud569\ub2c8\ub2e4. \ud558\ub098\ub294 \uc5ec\ub4dc\ub984 \ubcd1\ubcc0\uacfc \uad00\ub828\ub41c \ubbf8\uc0dd\ubb3c \ubc0f \uc5fc\uc99d \uc694\uc778\uc744 \ud45c\uc801\uc73c\ub85c \ud558\uace0, \ub2e4\ub978 \ud558\ub098\ub294 PIH \ud615\uc131\uc5d0 \uad00\uc5ec\ud558\ub294 \uc5fc\uc99d \ubc0f \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc18\uc751\uc744 \uc870\uc808\ud569\ub2c8\ub2e4. \uc774 \ub450 \uac00\uc9c0\ub97c \ud568\uaed8 \uc0ac\uc6a9\ud558\uc5ec \uc0c1\uc704 \uc870\uc808\uacfc \ud558\uc704 \uc0c9\uc18c \uc870\uc808\uc744 \uacb0\ud569\ud55c \uac1c\ub150\uc801\uc778 \uacc4\uce35\uc801 \uc811\uadfc \ubc29\uc2dd\uc744 \ud615\uc131\ud569\ub2c8\ub2e4.<\/p>\n\n      <h2>\uc5ec\ub4dc\ub984 \ud6c4 PIH \ubb38\uc81c<\/h2>\n\n      <h3>\ubbf8\ubc31\ub9cc\uc73c\ub85c\ub294 \ucda9\ubd84\ud558\uc9c0 \uc54a\uc740 \uc774\uc720<\/h3>\n\n      <p>\uc5ec\ub4dc\ub984 \ud6c4 PIH\ub294 \uc798 \ud655\ub9bd\ub41c \uc21c\uc11c\ub97c \ub530\ub985\ub2c8\ub2e4:<\/p>\n\n      <ol>\n        <li><em>\uc5ec\ub4dc\ub984\uade0<\/em> (<em>C. acnes<\/em>) \ud53c\uc9c0\uc120\ub0ad\uc744 \uc2dd\ubbfc\ud654\ud569\ub2c8\ub2e4<\/li>\n        <li>\uc138\uade0 \ub300\uc0ac\uc0b0\ubb3c\uc774 \uc8fc\ubcc0 \ud53c\ubd80\uc5d0 \uc5fc\uc99d \ubc18\uc751\uc744 \uc720\ubc1c\ud569\ub2c8\ub2e4<\/li>\n        <li>\uc5fc\uc99d \uc5f0\uc1c4 \ubc18\uc751 \u2014 \ud504\ub85c\uc2a4\ud0c0\uae00\ub780\ub518 E\u2082 \ubc0f \uae30\ud0c0 \ub9e4\uac1c\uccb4\ub97c \ud1b5\ud574 \u2014 \uba5c\ub77c\ub2cc \uc138\ud3ec\ub97c \uc790\uadf9\ud558\uc5ec \uba5c\ub77c\ub2cc \ud569\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4<\/li>\n        <li>\uc5fc\uc99d\uc774 \ud574\uacb0\ub418\uac70\ub098 (\ub610\ub294 \uc7a0\uc7ac\uc801\uc73c\ub85c \uacc4\uc18d\ub418\uac70\ub098) \uc794\uc5ec \uc5b4\ub450\uc6b4 \uc790\uad6d\uc778 PIH\ub97c \ub0a8\uae41\ub2c8\ub2e4<\/li>\n        <li>\uc138\uade0 \uc720\ubc1c \uc694\uc778\uc774 \uc81c\uc5b4\ub418\uc9c0 \uc54a\uc73c\uba74, \uc9c0\uc18d\uc801\uc778 \uc5ec\ub4dc\ub984 \ud65c\ub3d9\uc740 1\ub2e8\uacc4\ubd80\ud130 \uc21c\uc11c\ub97c \ub2e4\uc2dc \uc2dc\uc791\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4<\/li>\n      <\/ol>\n\n      <p>\ud45c\uc900 \ubbf8\ubc31 \ud65c\uc131 \uc131\ubd84 \u2014 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c\uc81c, \ube44\ud0c0\ubbfc C \uc720\ub3c4\uccb4, \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc \u2014 \ub294 4\ub2e8\uacc4(\uc0c9\uc18c\uce68\ucc29)\ub97c \ud574\uacb0\ud558\uc9c0\ub9cc 1-3\ub2e8\uacc4(\uc138\uade0 \uc720\ubc1c \uc694\uc778 \ubc0f \uc5fc\uc99d \uc5f0\uc1c4 \ubc18\uc751)\ub294 \ud574\uacb0\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4. \uc9c0\uc18d\uc801\uc778 \uc5ec\ub4dc\ub984 \ud65c\ub3d9\uc774 \uc788\ub294 \ud53c\ubd80\uc758 \uacbd\uc6b0, \uc774\ub294 \ubbf8\ubc31 \uce58\ub8cc\uac00 \uc0c8\ub85c\uc6b4 PIH\ub97c \uacc4\uc18d \uc0dd\uc131\ud558\ub294 \uc2dc\uc2a4\ud15c\uc5d0 \uc801\uc6a9\ub41c\ub2e4\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc9c0\uc18d\uc801\uc778 \uc5fc\uc99d \ud65c\ub3d9\uc774 \uc788\ub294 \uacbd\uc6b0 \uce58\ub8cc \ud6a8\uacfc\uac00 \uc810\ucc28 \uac10\uc18c\ud569\ub2c8\ub2e4.<\/p>\n\n      <p>\ud6a8\uacfc\uc801\uc778 \uc5ec\ub4dc\ub984 \ud6c4 PIH \ubcf5\uad6c\ub294 \ub450 \uac00\uc9c0 \uc218\uc900\uc5d0\uc11c \ub3d9\uc2dc\uc5d0 \uc791\uc6a9\ud574\uc57c \ud569\ub2c8\ub2e4: \uc5ec\ub4dc\ub984 \uad00\ub828 \uc5fc\uc99d \uc720\ubc1c \uc694\uc778\uacfc \uc0c9\uc18c\uce68\ucc29 \uacb0\uacfc.<\/p>\n\n      <h2>\uc774\uc911 \ud65c\uc131 \uc131\ubd84 \uad6c\uc870<\/h2>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_totarol_pih_cycle.png\"\n             alt=\"C. acnes \uad70\uc9d1\ubd80\ud130 \uc5fc\uc99d \uce90\uc2a4\ucf00\uc774\ub4dc, \uba5c\ub77c\ub2cc\uc138\ud3ec \ud65c\uc131\ud654 (MITF), \uba5c\ub77c\ub2cc \uc0dd\uc131, PIH\uc5d0 \uc774\ub974\ub294 \uc5ec\ub4dc\ub984 \ud6c4 PIH \uc8fc\uae30\uc640 \ud1a0\ud0c0\ub864\uc774 \ubc15\ud14c\ub9ac\uc544 \ub2e8\uacc4\uc5d0 \uac1c\uc785\ud558\uace0 \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc5fc\uc99d, PKA\/MITF, \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \ub2e8\uacc4\uc5d0 \uac1c\uc785\ud558\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\ub294 \ub2e4\uc774\uc5b4\uadf8\ub7a8\">\n        <figcaption>\uadf8\ub9bc 1 \u2014 \ud1a0\ud0c0\ub864 + \uae00\ub77c\ube0c\ub9ac\ub518 \uc774\uc911 \uac1c\uc785\uc744 \ud1b5\ud55c \uc5ec\ub4dc\ub984 \ud6c4 PIH \uc8fc\uae30. \ud1a0\ud0c0\ub864\uc740 1\ub2e8\uacc4\uc5d0\uc11c C. acnes\ub97c \ud45c\uc801\uc73c\ub85c \ud569\ub2c8\ub2e4. \uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec(\u2461), PKA\/MITF \uacbd\ub85c \uc5b5\uc81c(\u2462), \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \ud65c\uc131 \uc5b5\uc81c(\u2463)\ub97c \uc870\uc808\ud569\ub2c8\ub2e4. \ucd9c\ucc98: Yokota et al., 1998; Kubo et al., 1992; Nerya et al., 2003; Pan et al., 2023.<\/figcaption>\n      <\/figure>\n\n      <h3>\ud1a0\ud0c0\ub864: \uc138\uade0 \uc720\ubc1c \uc694\uc778 \ud45c\uc801\ud654<\/h3>\n\n      <p>\ud1a0\ud0c0\ub864\uc740 \uc2ec\uc7ac\uc5d0\uc11c \ucd94\ucd9c\ud55c \ub514\ud14c\ub974\ud39c \ud398\ub180\uc785\ub2c8\ub2e4 <em>\ud3ec\ub3c4\uce74\ub974\ud478\uc2a4 \ud1a0\ud0c0\ub77c<\/em>, \uc77c\ubc18\uc801\uc73c\ub85c \uc9c0\uc18d \uac00\ub2a5\ud55c \ubc29\uc2dd\uc73c\ub85c \uad00\ub9ac\ub418\ub294 \ub274\uc9c8\ub79c\ub4dc \uc232\uc5d0\uc11c \uacf5\uae09\ub429\ub2c8\ub2e4. COSMOS \uc778\uc99d \uc6d0\ub8cc\ub85c \uc81c\uacf5\ub418\uba70 \uc911\uad6d \ubcf8\ud1a0\uc5d0\uc11c\ub294 Huatai\ub97c \ud1b5\ud574 \ub3c5\uc810\uc801\uc73c\ub85c \uc720\ud1b5\ub429\ub2c8\ub2e4.<\/p>\n\n      <p><strong>\ud56d\uade0 \uba54\ucee4\ub2c8\uc998:<\/strong> \ud1a0\ud0c0\ub864\uc740 \uadf8\ub78c \uc591\uc131\uade0\uc5d0 \ub300\ud55c \ud56d\uade0 \ud65c\uc131\uc744 \ub098\ud0c0\ub0b4\uba70 \uc5b5\uc81c \ud6a8\uacfc\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. <em>C. acnes<\/em> \uc2dc\ud5d8\uad00 \ub0b4\uc5d0\uc11c. <em>\ud504\ub85c\ud53c\uc624\ub2c8\ubc15\ud14c\ub9ac\uc6c0 \uc544\ud06c\ub124\uc2a4<\/em> (\uc9c0\uae08 <em>C. acnes<\/em>)\ub294 \uc6d0\ub798 \ud1a0\ud0c0\ub864 \ud56d\uade0 \ud2b9\uc131 \uc5f0\uad6c(Kubo et al., 1992)\uc5d0\uc11c \uac00\uc7a5 \ubbfc\uac10\ud55c \ubc15\ud14c\ub9ac\uc544\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc81c\uc548\ub41c \uba54\ucee4\ub2c8\uc998\uc5d0\ub294 \uc77c\ubd80 \uc5f0\uad6c\uc5d0\uc11c \uc81c\uc548\ub41c FtsZ \uad00\ub828 \uacfc\uc815\uacfc \ud568\uaed8 \uc138\uade0 \uc138\ud3ec \ubd84\uc5f4 \ubc29\ud574\uac00 \ud3ec\ud568\ub418\uba70, \ud6a8\uacfc\uc801\uc778 \ub18d\ub3c4\uc5d0\uc11c \uc138\uade0 \ub9c9 \ubb34\uacb0\uc131 \ud30c\uad34\ub3c4 \ud3ec\ud568\ub429\ub2c8\ub2e4.<\/p>\n\n      <p>\ud1a0\ud0c0\ub864\uc740 \ub610\ud55c \ud56d\uc0b0\ud654 \ud65c\uc131\uc744 \ub098\ud0c0\ub0b4\uba70 \ud53c\uc9c0 \uad00\ub828 \ud658\uacbd\uc5d0\uc11c \uc9c0\uc9c8 \uc0b0\ud654\ub97c \uc904\uc774\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc9c0\uc9c8 \uc0b0\ud654 \uc0dd\uc131\ubb3c\uc740 \uc5ec\ub4dc\ub984\uc774 \ubc1c\uc0dd\ud558\uae30 \uc26c\uc6b4 \ud53c\ubd80\uc758 \uba74\ud3ec \ud615\uc131 \ubc0f \uc5fc\uc99d \uacfc\uc815\uacfc \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <p><strong>\ucd94\uac00 \ud65c\uc131:<\/strong> \ud1a0\ud0c0\ub864\uc740 \ubb38\uc11c\ud654\ub41c \ud56d\uc0b0\ud654 \ud65c\uc131\uc744 \uac00\uc9c0\uace0 \uc788\uc73c\uba70 \ud53c\ubd80 \uad00\ub828 \ud658\uacbd\uc5d0\uc11c ROS \uac10\uc18c\uc5d0 \uae30\uc5ec\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \ud6a8\uacfc\ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \ud56d\uc0b0\ud654 \ud65c\uc131\uacfc \uc2dc\ub108\uc9c0 \ud6a8\uacfc\ub97c \ubc1c\ud718\ud558\uc5ec \uc804\ubc18\uc801\uc778 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n\n      <p><strong>\uc81c\ud615 \ud504\ub85c\ud544:<\/strong><\/p>\n      <ul>\n        <li>\uc9c0\uc6a9\uc131; \uc624\uc77c \ub610\ub294 \ud3f4\ub9ac\uc62c \uc0c1\uc5d0 \uc18d\ud568<\/li>\n        <li>COSMOS \uc778\uc99d (Totarol 99%, 100% PPAI)<\/li>\n        <li>\ub3d9\uc77c \uc0c1\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud638\ud658 \uac00\ub2a5<\/li>\n        <li>\uc77c\ubc18\uc801\uc778 \ud654\uc7a5\ud488 \uc0ac\uc6a9\ub7c9: 0.05\u20130.2%<\/li>\n      <\/ul>\n\n      <h3>\uae00\ub77c\ube0c\ub9ac\ub518: \uc5fc\uc99d \ubc0f \uba5c\ub77c\ub2cc \uc0dd\uc131 \uacb0\uacfc \uad00\ub9ac<\/h3>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc5ec\ub7ec \uba54\ucee4\ub2c8\uc998\uc744 \ud1b5\ud574 \uc5ec\ub4dc\ub984 \ud6c4 PIH \uacb0\uacfc\uc5d0 \ub300\ucc98\ud569\ub2c8\ub2e4:<\/p>\n\n      <p><strong>\ud56d\uc5fc\uc99d \ud65c\uc131:<\/strong> \uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc138\ud3ec \ubaa8\ub378\uc5d0\uc11c COX-2 \ubc0f \uad00\ub828 \ub9e4\uac1c\uccb4\uc758 \ubcf4\uace0\ub41c \ud558\ud5a5 \uc870\uc808\uc744 \ud3ec\ud568\ud558\uc5ec \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c \uc870\uc808\uc744 \ud1b5\ud574 \ud56d\uc5fc\uc99d \ud6a8\uacfc\ub97c \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc774\ub294 \uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29\uacfc \uad00\ub828\ub41c \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec\uc744 \uc904\uc774\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4.<\/p>\n\n      <p><strong>PKA\/MITF \ubc0f MAPK\/MITF \uacbd\ub85c \uc5b5\uc81c:<\/strong> \uae00\ub77c\ube0c\ub9ac\ub518\uc740 PKA\/MITF \ubc0f MAPK\/MITF \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \ubaa8\ub450 \uc5b5\uc81c\ud558\uc5ec \uba5c\ub77c\ub2cc \uc138\ud3ec\uc5d0\uc11c MITF, TYR, TRP-1 \ubc0f TRP-2\uc758 \uc804\uc0ac \ubc0f \ub2e8\ubc31\uc9c8 \ubc1c\ud604\uc744 \ud06c\uac8c \ud558\ud5a5 \uc870\uc808\ud558\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4(Pan et al., 2023). \uc774\ub7ec\ud55c \uc0c1\uc704 \uc804\uc0ac \uc5b5\uc81c\ub294 \ud6a8\uc18c \ub2e8\uacc4\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc0c8\ub85c\uc6b4 \uba5c\ub77c\ub2cc \uc0dd\uc131\uc758 \uadfc\ubcf8 \uc6d0\uc778\uc744 \ud574\uacb0\ud558\ub294 \ud65c\uc131\ud654\ub41c \uba5c\ub77c\ub2cc \uc138\ud3ec\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ub2a5\ub825\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n\n      <p><strong>\ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c:<\/strong> \uae00\ub77c\ube0c\ub9ac\ub518\uc740 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \ud65c\uc131\uc744 \uc5b5\uc81c\ud558\uace0 \uba5c\ub77c\ub2cc \ud569\uc131\uc744 \uac10\uc18c\uc2dc\ucf1c \uc0c8\ub85c\uc6b4 \uba5c\ub77c\ub2cc \uc0dd\uc131\uc744 \uac10\uc18c\uc2dc\ud0b5\ub2c8\ub2e4(IC\u2085\u2080 = 0.09 \u03bcmol\/L, Nerya et al., 2003).<\/p>\n\n      <p><strong>\ud56d\uc0b0\ud654 ROS \uc81c\uac70:<\/strong> \uc138\ud3ec \ub0b4 \ud65c\uc131 \uc0b0\uc18c\uc885(ROS)\uc744 \uac10\uc18c\uc2dc\ucf1c \uc5fc\uc99d \ubc0f \uba5c\ub77c\ub2cc \uc0dd\uc131\uc5d0 \uae30\uc5ec\ud560 \uc218 \uc788\ub294 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4\ub97c \ub0ae\ucda5\ub2c8\ub2e4.<\/p>\n\n      <h3>\uacc4\uce35\uc801 \ucee4\ubc84\ub9ac\uc9c0 \ud504\ub808\uc784\uc6cc\ud06c<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc0c1<\/th>\n              <th>\ud65c\uc131<\/th>\n              <th>\uae30\uad6c<\/th>\n              <th>\uacb0\uacfc<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>\uc608\ubc29<\/strong><\/td>\n              <td>\ud1a0\ud0c0\ub864<\/td>\n              <td><em>C. acnes<\/em> \ud56d\uade0 \ud65c\uc131; \uc81c\uc548\ub41c \ub9c9 \uad00\ub828 \ud6a8\uacfc<\/td>\n              <td>\uc138\uade0 \uc720\ubc1c \uc694\uc778 \ubc0f \ubaa8\ub0ad \uc5fc\uc99d \ud658\uacbd \uac10\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\uc2e0\ud638 \uc870\uc808<\/strong><\/td>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518 (\ud56d\uc5fc\uc99d \ud65c\uc131)<\/td>\n              <td>\ubcf4\uace0\ub41c COX-2 \ubc1c\ud604 \uc870\uc808\uc744 \ud3ec\ud568\ud55c \ud56d\uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec<\/td>\n              <td>\uc794\uc5ec \ub610\ub294 \ud574\uacb0\ub41c \uc5fc\uc99d\uc73c\ub85c\ubd80\ud130\uc758 \uc5fc\uc99d\uc131 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uc2e0\ud638 \uac10\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\uc804\uc0ac \uc870\uc808<\/strong><\/td>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518 (PKA\/MITF)<\/td>\n              <td>PKA\/MITF \ubc0f MAPK\/MITF \uacbd\ub85c \uc5b5\uc81c; MITF\u2193; TYR \ubc1c\ud604\u2193<\/td>\n              <td>\uc804\uc0ac \uc218\uc900\uc5d0\uc11c \uba5c\ub77c\ub2cc \uc0dd\uc131 \ub2a5\ub825 \uac10\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ud569\uc131 \uc5b5\uc81c<\/strong><\/td>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518 (\ud2f0\ub85c\uc2dc\ub098\uc544\uc81c)<\/td>\n              <td>\ube44\uacbd\uc7c1\uc801 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c<\/td>\n              <td>\uc0c8\ub85c\uc6b4 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uac10\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\uc0b0\ud654 \uc81c\uc5b4<\/strong><\/td>\n              <td>\ud1a0\ud0c0\ub864 + \uae00\ub77c\ube0c\ub9ac\ub518<\/td>\n              <td>ROS \uc81c\uac70 (\ub450 \ud65c\uc131 \uc131\ubd84 \ubaa8\ub450)<\/td>\n              <td>\uc5fc\uc99d \ubc0f \uba5c\ub77c\ub2cc \uc0dd\uc131\uc5d0 \uae30\uc5ec\ud558\ub294 \uc0b0\ud654 \uc2a4\ud2b8\ub808\uc2a4 \uac10\uc18c\uc5d0 \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>\uc774\uac83\uc740 \ud56d\uade0 \ucca8\uac00\uc81c\uac00 \ud3ec\ud568\ub41c \ube0c\ub77c\uc774\ud2b8\ub2dd \uc81c\ud615\uc774\ub098 \uc0c9\uc18c \uce68\ucc29\uc744 \ub098\uc911\uc5d0 \uace0\ub824\ud55c \uc5ec\ub4dc\ub984 \uc81c\ud615\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc774\uac83\uc740 \uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c \uce68\ucc29\uacfc \uad00\ub828\ub41c \uc5ec\ub7ec \uc0c1\ud638 \uc5f0\uacb0\ub41c \uacbd\ub85c\ub97c \ud574\uacb0\ud558\uae30 \uc704\ud574 \uc124\uacc4\ub41c \uc2dc\uc2a4\ud15c\uc785\ub2c8\ub2e4.<\/p>\n\n      <h2>\uc804\uccb4 \uc2dc\uc2a4\ud15c\uc744 \uc704\ud55c \uc0c1\ud638 \ubcf4\uc644\uc801\uc778 \ud65c\uc131 \uc131\ubd84<\/h2>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ud65c\uc131<\/th>\n              <th>\uc5ed\ud560<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>\ud2b8\ub77c\ub125\uc0bc\uc0b0 (TXA)<\/strong><\/td>\n              <td>\uac01\uc9c8\uc138\ud3ec-\uba5c\ub77c\ub2cc\uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec \uc870\uc808 (\ud50c\ub77c\uc2a4\ubbfc \uad00\ub828 \uacbd\ub85c\ub97c \ud1b5\ud574)<\/td>\n              <td>\uc218\uc6a9\uc131; \uc218\uc131 \uc0c1\uc5d0 \ucca8\uac00; pH 4.5\u20136.0\uc5d0\uc11c \ud638\ud658 \uac00\ub2a5<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ub098\uc774\uc544\uc2e0\uc544\ubbf8\ub4dc<\/strong><\/td>\n              <td>\uba5c\ub77c\ub178\uc19c \uc804\ub2ec \uac10\uc18c; \ud53c\uc9c0 \uc870\uc808 (\uc5ec\ub4dc\ub984 \ud53c\ubd80\uc5d0 \uad00\ub828\ub428)<\/td>\n              <td>2\u20135% (w\/w); \uc218\uc131 \uc0c1<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ub9ac\ucf54\uce7c\ucf58 A<\/strong><\/td>\n              <td>\ud56d\uc5fc; \ud53c\uc9c0 \uc870\uc808; \uc57d\ud55c \ube0c\ub77c\uc774\ud2b8\ub2dd \ud6a8\uacfc<\/td>\n              <td>\uac10\ucd08 \uc720\ub798; \uc720\uc131 \uc0c1 \ud638\ud658; COSMOS \uc778\uc99d<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\uc9d5\ud06c PCA<\/strong><\/td>\n              <td>\ud53c\uc9c0 \uc870\uc808; \ud56d\uc5fc; \uc9c0\uc6d0 <em>C. acnes<\/em> \ud658\uacbd \uad50\ub780<\/td>\n              <td>\uc218\uc6a9\uc131; 0.1\u20130.5% (w\/w)<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\uc544\uc824\ub77c\uc775\uc0b0<\/strong><\/td>\n              <td>\uac01\uc9c8 \ud615\uc131 \uc870\uc808; \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c; <em>C. acnes<\/em> \ud65c\uc131 \uac10\uc18c<\/td>\n              <td>\uc5ec\ub7ec \uc5ec\ub4dc\ub984 \ud6c4 \ud45c\uc801\uc744 \ud574\uacb0; pH 4.5\u20136.5<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout\">\n        <p><strong>\uc544\uc824\ub77c\uc775\uc0b0\uc5d0 \ub300\ud55c \ucc38\uace0 \uc0ac\ud56d:<\/strong> \uc544\uc824\ub77c\uc775\uc0b0\uacfc \uae00\ub77c\ube0c\ub9ac\ub518\uc740 pH \ud638\ud658\uc131\uc774 \uc788\uc73c\uba70 \uc5ec\ub4dc\ub984 \ud6c4 PIH \uc2dc\uc2a4\ud15c\uc758 \ub2e4\ub978 \uce21\uba74\uc744 \ud574\uacb0\ud569\ub2c8\ub2e4. \uc544\uc824\ub77c\uc775\uc0b0\uc740 \uac01\uc9c8 \ud615\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\uba70 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc0f <em>C. acnes<\/em>\uc5d0 \ucd94\uac00\uc801\uc778 \ud65c\uc131\uc744 \ub098\ud0c0\ub0b4\ub294 \ubc18\uba74, \uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc8fc\ub85c \uba5c\ub77c\ub2cc \ud569\uc131 \ubc0f \uc5fc\uc99d \uc2e0\ud638 \uc804\ub2ec\uc744 \ud45c\uc801\uc73c\ub85c \ud569\ub2c8\ub2e4. \uc774 \uc870\ud569\uc740 \uae30\ub2a5\uc801\uc73c\ub85c \uc0c1\ud638 \ubcf4\uc644\uc801\uc785\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <h2>\uc81c\ud615 \uc9c0\uce68<\/h2>\n\n      <h3>\uc81c\ud615 \ubc0f \ubca0\uc774\uc2a4 \uace0\ub824 \uc0ac\ud56d<\/h3>\n\n      <p>\uc5ec\ub4dc\ub984 \ud6c4 \ubc0f \uc5ec\ub4dc\ub984\uc131 \ud53c\ubd80\ub294 \uac00\ubccd\uace0 \ube44\uba74\ud3ec\uc131 \uc81c\ud615\uc758 \uc774\uc810\uc744 \uc5bb\uc2b5\ub2c8\ub2e4. \ubb34\uac70\uc6b4 \uc5f0\ud654 \uc5d0\uc2a4\ud14c\ub974, \uace0\uc810\ub3c4 \uc2e4\ub9ac\ucf58 \ubc0f \ub450\uaebc\uc6b4 \ud06c\ub9bc \ubca0\uc774\uc2a4\ub294 \ubc00\ud3d0\uc131\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \uc774\ub294 \uc5ec\ub4dc\ub984\uc131 \ud53c\ubd80\uc5d0\uc11c \ub35c \uc720\ub9ac\ud55c \ubaa8\ub0ad \ud658\uacbd\uc5d0 \uae30\uc5ec\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <p>\uad8c\uc7a5 \ubca0\uc774\uc2a4 \uc811\uadfc \ubc29\uc2dd:<\/p>\n      <ul>\n        <li>\uac00\ubcbc\uc6b4 \uc720\uccb4 \uc5d0\uba40\uc83c (O\/W, \uc800\uc720\uc0c1, \u226415% (w\/w))<\/li>\n        <li>\uc801\uc808\ud55c \uc6a9\ud574\ub97c \ud1b5\ud55c \ud1a0\ud0c0\ub864 \ubc0f \uae00\ub77c\ube0c\ub9ac\ub518 \ud568\uc720 \uc218\uc131 \uc138\ub7fc<\/li>\n        <li>\uac00\ubcbc\uc6b4 \uc5d0\uc2a4\ud14c\ub974 \uae30\ubc18 \uc138\ub7fc (\uc774\uc18c\ub178\ub2d0 \uc774\uc18c\ub178\ub098\ub178\uc5d0\uc774\ud2b8, C12\u201315 \uc54c\ud0ac \ubca4\uc870\uc5d0\uc774\ud2b8) \u2014 \uc800\uc810\ub3c4, \ud53c\ubd80 \ud638\ud658 \uc5f0\ud654\uc81c<\/li>\n      <\/ul>\n\n      <h3>\ub4f1\uae09 \uad8c\uc7a5 \uc0ac\ud56d<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ud65c\uc131<\/th>\n              <th>\uad8c\uc7a5 \ub4f1\uae09<\/th>\n              <th>\uc0c1<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518<\/td>\n              <td>40% \ubc31\uc0c9 \ubd84\ub9d0<\/td>\n              <td>\ud3f4\ub9ac\uc62c \uc0c1 (\uc0ac\uc804 \uc6a9\ud574)<\/td>\n              <td>\ud53c\ubd80 \ud638\ud658 \uc5d0\uc2a4\ud14c\ub974 \ub610\ub294 \ud3f4\ub9ac\uc62c \uc2dc\uc2a4\ud15c \uc120\ud638<\/td>\n            <\/tr>\n            <tr>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518<\/td>\n              <td>90% \uc624\uc77c \uac00\uc6a9\uc131<\/td>\n              <td>\uc720\uc131 \uc0c1 (\uc720\ubd84 \ud3ec\ud568 \uc2dc)<\/td>\n              <td>\uc77c\ubc18\uc801\uc778 \uc0ac\uc6a9 \uc218\uc900: ~0.2% (w\/w)<\/td>\n            <\/tr>\n            <tr>\n              <td>\ud1a0\ud0c0\ub864<\/td>\n              <td>99% COSMOS \uc778\uc99d<\/td>\n              <td>\uc624\uc77c \uc0c1<\/td>\n              <td>0.05\u20130.2%<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <h3>\ubaa9\ud45c \uc0ac\uc6a9 \uc218\uc900<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ud65c\uc131<\/th>\n              <th>\ubaa9\ud45c \uc218\uc900<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518<\/td>\n              <td>1\u20130.3% (w\/w) \ud65c\uc131 \uc131\ubd84<\/td>\n              <td>\ucd5c\uc885 \uc81c\ud488\uc758 \ucd5c\uc885 \ud65c\uc131 \uc131\ubd84 \ud568\ub7c9\uc73c\ub85c \ud45c\uc2dc<\/td>\n            <\/tr>\n            <tr>\n              <td>\ud1a0\ud0c0\ub864<\/td>\n              <td>0.05\u20130.2%<\/td>\n              <td>\uc81c\ud615 \uc2dc\uc2a4\ud15c\uc5d0 \ub530\ub77c \uc77c\ubc18\uc801\uc778 \ud654\uc7a5\ud488 \uc0ac\uc6a9 \ubc94\uc704<\/td>\n            <\/tr>\n            <tr>\n              <td>TXA<\/td>\n              <td>2-5%<\/td>\n              <td>\uc218\uc131 \uc0c1<\/td>\n            <\/tr>\n            <tr>\n              <td>\ub098\uc774\uc544\uc2e0\uc544\ubbf8\ub4dc<\/td>\n              <td>2-5%<\/td>\n              <td>\uc218\uc131 \uc0c1<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc9d5\ud06c PCA<\/td>\n              <td>1\u20130.5%<\/td>\n              <td>\uc218\uc131 \uc0c1<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <h3>pH \uad00\ub9ac<\/h3>\n\n      <p><strong>\ubaa9\ud45c pH: 4.5\u20135.5<\/strong><\/p>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uacfc TXA \ubaa8\ub450 \uc77c\ubc18\uc801\uc778 \uc81c\ud615 \uc870\uac74\uc5d0\uc11c \uc774 pH \ubc94\uc704\uc640 \ud638\ud658\ub429\ub2c8\ub2e4. \uc544\uc824\ub77c\uc775\uc0b0 (\ud3ec\ud568 \uc2dc)\uc740 pH 4.5\u20136.5\uc5d0\uc11c \ud6a8\uacfc\uc801\uc785\ub2c8\ub2e4. \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc\ub294 pH 5.0\u20137.0\uc5d0\uc11c \uc791\uc6a9\ud569\ub2c8\ub2e4. \u2014 \ub0ae\uc740 \ubc94\uc704\ub294 \uc801\uc808\ud55c \uc81c\ud615 \uc81c\uc5b4\ub85c \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uad6c\uc5f0\uc0b0\/\uad6c\uc5f0\uc0b0 \ub098\ud2b8\ub968\uc73c\ub85c \uc644\ucda9\ud558\uc2ed\uc2dc\uc624. \ubaa8\ub4e0 \ub0c9\uac01 \ucca8\uac00 \ud6c4 pH\ub97c \ud655\uc778\ud558\uc2ed\uc2dc\uc624.<\/p>\n\n      <h2>\uc5ec\ub4dc\ub984 \ud6c4 PIH \uc138\ub7fc \u2014 \uad6c\uc870 \uccad\uc0ac\uc9c4<\/h2>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc0c1<\/th>\n              <th>Ingredient<\/th>\n              <th>\ubaa9\ud45c 1%<\/th>\n              <th>\uae30\ub2a5<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\uc815\uc81c\uc218<\/td>\n              <td>\uc801\ub7c9<\/td>\n              <td>\uce90\ub9ac\uc5b4; \uc644\ucda9\uc561<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\uad6c\uc5f0\uc0b0 \/ \uad6c\uc5f0\uc0b0\ub098\ud2b8\ub968<\/td>\n              <td>\uc644\ucda9\uc81c<\/td>\n              <td>\ud65c\uc131 \uc131\ubd84 \uc804 \ubaa9\ud45c pH 4.8\u20135.0<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\ub514\uc18c\ub4d0 EDTA<\/td>\n              <td>05\u20130.1% (w\/w)<\/td>\n              <td>\uae08\uc18d \ud0ac\ub808\uc774\uc158<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\ub098\uc774\uc544\uc2e0\uc544\ubbf8\ub4dc<\/td>\n              <td>2-5%<\/td>\n              <td>\uba5c\ub77c\ub178\uc19c \uc804\ub2ec \uac10\uc18c; \ud53c\uc9c0 \uc870\uc808<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\ud2b8\ub77c\ub125\uc0ac\ubbf9\uc0b0<\/td>\n              <td>2-5%<\/td>\n              <td>\uac01\uc9c8\uc138\ud3ec-\uba5c\ub77c\ub2cc\uc138\ud3ec \uc2e0\ud638 \uc804\ub2ec \uc870\uc808 (\ud50c\ub77c\uc2a4\ubbfc \uad00\ub828 \uacbd\ub85c)<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\uc9d5\ud06c PCA<\/td>\n              <td>1\u20130.5%<\/td>\n              <td>\ud53c\uc9c0 \uc870\uc808; \ud56d\uc5fc<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \uc0c1<\/td>\n              <td>\uc544\uc824\ub77c\uc775\uc0b0 (\ud3ec\ud568 \uc2dc)<\/td>\n              <td>5\u201310%<\/td>\n              <td>\uac01\uc9c8 \ud615\uc131 \uc870\uc808; \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c; <em>C. acnes<\/em> \ud65c\uc131 \uac10\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc624\uc77c\/\ud3f4\ub9ac\uc62c \ub2e8\uacc4<\/td>\n              <td>\ube44\uba74\ud3ec\uc131 \uc5d0\uc2a4\ud14c\ub974<\/td>\n              <td>5\u201315% (w\/w)<\/td>\n              <td>\uacbd\ub7c9 \uce90\ub9ac\uc5b4<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc624\uc77c\/\ud3f4\ub9ac\uc62c \ub2e8\uacc4<\/td>\n              <td><strong>\uae00\ub77c\ube0c\ub9ac\ub518 40% \ubc31\uc0c9 (\uc0ac\uc804 \uc6a9\ud574)<\/strong><\/td>\n              <td>1\u20130.3% (w\/w) \ud65c\uc131 \uc131\ubd84<\/td>\n              <td>\uc8fc\uc694 \ube0c\ub77c\uc774\ud2b8\ub2dd \uc575\ucee4; \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c; \ud56d\uc5fc<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc624\uc77c\/\ud3f4\ub9ac\uc62c \ub2e8\uacc4<\/td>\n              <td><strong>\ud1a0\ud0c0\ub864 99%<\/strong><\/td>\n              <td>0.05\u20130.2%<\/td>\n              <td>\ud56d\uade0 \ud65c\uc131 <em>C. acnes<\/em>; \uc9c0\uc6a9\uc131 \ud56d\uc0b0\ud654\uc81c<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc624\uc77c\/\ud3f4\ub9ac\uc62c \ub2e8\uacc4<\/td>\n              <td>\ud63c\ud569 \ud1a0\ucf54\ud398\ub864<\/td>\n              <td>2\u20130.5% (w\/w)<\/td>\n              <td>\uc9c0\uc6a9\uc131 \ud56d\uc0b0\ud654\uc81c (\uac15\ub825 \uad8c\uc7a5)<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc720\ud654\uc81c<\/td>\n              <td>\ub0ae\uc740 HLB + \ub192\uc740 HLB \uc870\ud569<\/td>\n              <td>\ud544\uc694\uc5d0 \ub530\ub77c<\/td>\n              <td>\uac00\ubccd\uace0 \uae30\ub984\uc9c0\uc9c0 \uc54a\uc740 \uc720\ud654<\/td>\n            <\/tr>\n            <tr>\n              <td>\ub0c9\uac01<\/td>\n              <td>\ud544\uc694\ud55c \uacbd\uc6b0 pH \ubcf4\uc815<\/td>\n              <td>\u2014<\/td>\n              <td>\uad6c\uc5f0\uc0b0 \uc6a9\uc561 (10% w\/w)<\/td>\n            <\/tr>\n            <tr>\n              <td>\ub0c9\uac01<\/td>\n              <td>\ubc29\ubd80 \uc2dc\uc2a4\ud15c<\/td>\n              <td>\ud544\uc694\uc5d0 \ub530\ub77c<\/td>\n              <td>pH 4.5\u20135.5\uc5d0 \uc801\ud569<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout\">\n        <p>\ubaa8\ub4e0 \ubc30\uce58\uc5d0\ub294 COA, TDS \ubc0f SDS\/MSDS\uac00 \ud568\uaed8 \uc81c\uacf5\ub429\ub2c8\ub2e4. \ucd94\uac00 \ud14c\uc2a4\ud2b8\ub294 \uc694\uccad \uc2dc \uac00\ub2a5\ud569\ub2c8\ub2e4.<\/p>\n        <p style=\"margin-top:8px\">Huatai\ub294 <strong>\uc911\uad6d \ubcf8\ud1a0\uc5d0\uc11c \ud1a0\ud0c0\ub864\uc758 \ub3c5\uc810 \uc720\ud1b5\uc5c5\uccb4\uc785\ub2c8\ub2e4<\/strong>\ud1a0\ud0c0\ub864 \uc0d8\ud50c \ubc0f \uae30\uc220 \ub370\uc774\ud130 \uc2dc\ud2b8\ub294 \uc694\uccad \uc2dc \uc81c\uacf5\ub429\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <!-- Related -->\n      <div class=\"related-section\">\n        <h2>\uad00\ub828 \uc790\ub8cc<\/h2>\n        <div class=\"related-links\">\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/glabridin\/\">\n            <span>\ud654\uc7a5\ud488 \uc81c\ud615\uc744 \uc704\ud55c \uae00\ub77c\ube0c\ub9ac\ub518 \uac00\uc774\ub4dc \u2014 \uc644\uc804 \uae30\uc220 \ucc38\uc870<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\uc804\uccb4 \uba54\ucee4\ub2c8\uc998, \uc2dc\ub108\uc9c0 \ub9f5 \ubc0f \uc81c\ud615 \ud504\ub85c\ud1a0\ucf5c<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/can-glabridin-be-used-in-sensitive-skin-products\/\">\n            <span>\ubbfc\uac10\uc131 \ud53c\ubd80 \uc81c\ud488\uc5d0 \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub098\uc694?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\uc548\uc804 \ub370\uc774\ud130 \ubc0f PIH \ud3ec\uc9c0\uc154\ub2dd<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/glabridin-tranexamic-acid-txa-different-mechanisms-complementary-benefits\/\">\n            <span>\uae00\ub77c\ube0c\ub9ac\ub518 \ubc0f \ud2b8\ub77c\ub125\uc0bc\uc0b0: \ub2e4\ub978 \uba54\ucee4\ub2c8\uc998, \uc0c1\ud638 \ubcf4\uc644\uc801\uc778 \uc774\uc810<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\uc0c1\uc704 PIH \uc2e0\ud638 \uc870\uc808<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/glabridin-niacinamide-complementary-mechanisms-in-multilevel-brightening\/\">\n            <span>\uae00\ub77c\ube0c\ub9ac\ub518 &amp; \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc: \ub2e4\ub2e8\uacc4 \ubbf8\ubc31\uc744 \uc704\ud55c \uc0c1\ud638 \ubcf4\uc644\uc801 \uba54\ucee4\ub2c8\uc998<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\uba5c\ub77c\ub178\uc19c \uc804\ub2ec \ubc0f \ud558\uc704 \ubc94\uc704<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n        <\/div>\n      <\/div>\n\n      <!-- CTA -->\n      <div class=\"cta-box\">\n        <div class=\"cta-box-text\">\n          <strong>\uc0d8\ud50c, COA \ub610\ub294 \uae30\uc220 \uc0c1\ub2f4 \uc694\uccad<\/strong>\n          glabridinchina.com \u00b7 jelly@huataibio.com \u00b7 +86 17868678161\n        <\/div>\n        <a class=\"cta-btn\" href=\"https:\/\/glabridinchina.com\/ko\/product-tag\/\">\ubb38\uc758\ud558\uae30 \u2192<\/a>\n      <\/div>\n\n      <!-- References -->\n      <div class=\"references\">\n        <h2>\ucc38\uace0 \uc790\ub8cc<\/h2>\n        <ol>\n          <li>Yokota T, Nishio H, Kubota Y, Mizoguchi M. \uac10\ucd08 \ucd94\ucd9c\ubb3c\uc5d0\uc11c \ucd94\ucd9c\ud55c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc0f \uc5fc\uc99d \uc5b5\uc81c \ud6a8\uacfc. <em>Pigment Cell Research<\/em>, 11(6), 355\u2013361, 1998. DOI: 10.1111\/j.1600-0749.1998.tb00494.x.<\/li>\n          <li>Kubo I, Muroi H, Himejima M. \ud1a0\ud0c0\ub864\uc758 \ud56d\uade0 \ud65c\uc131 \ubc0f \ud6a8\ub2a5 \uc99d\uc9c4. <em>\ucc9c\uc5f0\ubb3c\ud559\ud68c\uc9c0<\/em>, 55(10), 1436\u20131440, 1992. DOI: 10.1021\/np50088a008. PMID: 1453180. \u2014 <em>Propionibacterium acnes\ub294 \ud1a0\ud0c0\ub864\uc5d0 \uac00\uc7a5 \ubbfc\uac10\ud55c \ubc15\ud14c\ub9ac\uc544\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/em><\/li>\n          <li>Nerya O, Vaya J, Musa R, Izrael S, Ben-Arie R, Tamir S. \uac10\ucd08 \ubfcc\ub9ac\uc5d0\uc11c \ucd94\ucd9c\ud55c \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c\uc81c\uc778 \uae00\ub77c\ube0c\ub80c\uacfc \uc774\uc18c\ub9ac\ud034\ub9ac\ud2f0\uac8c\ub2cc. <em>\ub18d\uc5c5 \ubc0f \uc2dd\ud488 \ud654\ud559 \uc800\ub110<\/em>, 51(5), 1201\u20131207, 2003. \u2014 <em>IC\u2085\u2080 \ube44\uad50 \ub370\uc774\ud130.<\/em><\/li>\n          <li>Pan C, Liu X, Zheng Y, et al. \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uc5b5\uc81c \uba54\ucee4\ub2c8\uc998: \ubd84\uc790 \ub3c4\ud0b9, PKA\/MITF \ubc0f MAPK\/MITF \uacbd\ub85c. <em>\uc2dd\ud488 \uacfc\ud559 \ubc0f \uc778\uac04 \uac74\uac15<\/em>, 12(1), 212\u2013222, 2023. DOI: 10.1016\/j.fshw.2022.07.011.<\/li>\n          <li>Maeda K, Nishino H. \ucf00\ub77c\ud2f0\ub178\uc0ac\uc774\ud2b8 \uc870\uac74 \ubc30\uc9c0\uac00 \uc788\ub294 \ubc30\uc591\ub41c \uc778\uac04 \uba5c\ub77c\ub2cc \uc138\ud3ec\uc5d0\uc11c \ud2b8\ub77c\ub125\uc0bc\uc0b0\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \uc5b5\uc81c \ud6a8\uacfc \uba54\ucee4\ub2c8\uc998. <em>\uac74\uac15\uacfc\ud559\ud68c\uc9c0<\/em>, 53(4), 389\u2013396, 2007. DOI: 10.1248\/jhs.53.389.<\/li>\n          <li>Guangdong Weipu Testing Technology Co., Ltd. (CMA No. 202119135666). \ubcf4\uace0\uc11c \ubc88\ud638 GZA01-23080632-JC-01. \uc778\uccb4 \ud53c\ubd80 \ubbf8\ubc31 \ud6a8\ub2a5 \uc5f0\uad6c, 0.03% \uae00\ub77c\ube0c\ub9ac\ub518. Huatai Bio-Fine Chemical \uc758\ub8b0.<\/li>\n        <\/ol>\n      <\/div>\n\n      <div class=\"article-footer\">\n        <p>\uc804\ubb38 \ud654\uc7a5\ud488 \uc81c\ud615 \uac1c\ubc1c\uc790 \ubc0f \uc5f0\uad6c\uac1c\ubc1c \ub2f4\ub2f9\uc790\ub97c \uc704\ud55c \uc790\ub8cc\uc785\ub2c8\ub2e4. \uaddc\uc81c \uad00\ub828 \uc870\uc5b8\uc744 \uad6c\uc131\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<br>\n        \ubc1c\ud589 2026\ub144 \u2014 Huatai Bio-Fine Chemical, Xi'an, Shaanxi, China.<\/p>\n      <\/div>\n\n    <\/article>\n  <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>\uc801\uc6a9 \uae00\ub77c\ube0c\ub9ac\ub518 \ud1a0\ud0c0\ub864 \uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29 \uc5ec\ub4dc\ub984 \ud6c4 \uc0c9\uc18c\uce68\ucc29\uc740 \uc790\uc678\uc120 \uc720\ubc1c \uc0c9\uc18c\uce68\ucc29 \ubc0f \uae30\ubbf8\uc640\ub294 \ubcd1\ub9ac\ud559\uc801 \uc6d0\uc778\uc774 \ub2e4\ub978 \uc5fc\uc99d \ud6c4 \uacfc\uc0c9\uc18c\uce68\ucc29(PIH)\uc758 \ud55c \ud615\ud0dc\uc785\ub2c8\ub2e4. \uc81c\ud615\uc740\u2026<\/p>","protected":false},"author":8,"featured_media":5935,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[411],"tags":[],"class_list":["post-14290","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-application-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Post-Acne PIH Repair: Combining Glabridin and Totarol | Huatai Bio-Fine Chemical<\/title>\n<meta name=\"description\" content=\"A technical guide to formulating post-acne PIH repair products using glabridin and Totarol \u2014 covering the PIH cycle mechanism, dual-active system design, and formulation blueprints for serum and light emulsion formats. 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