{"id":14105,"date":"2026-06-10T00:59:11","date_gmt":"2026-06-10T00:59:11","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=14105"},"modified":"2026-06-10T01:37:53","modified_gmt":"2026-06-10T01:37:53","slug":"what-ph-range-does-glabridin-require-in-cosmetic-formulations%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ko\/what-ph-range-does-glabridin-require-in-cosmetic-formulations%ef%bc%9f\/","title":{"rendered":"\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc694\uad6c\ud558\ub294 pH \ubc94\uc704\ub294 \uc5bc\ub9c8\uc778\uac00\uc694?"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14105\" class=\"elementor elementor-14105\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-170677b e-flex e-con-boxed e-con e-parent\" data-id=\"170677b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3820bf8 elementor-widget elementor-widget-html\" data-id=\"3820bf8\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t  <link rel=\"canonical\" href=\"https:\/\/glabridinchina.com\/faq\/what-ph-range-does-glabridin-require\/\">\n  <script type=\"application\/ld+json\">{\n    \"@context\": \"https:\\\/\\\/schema.org\",\n    \"@type\": \"FAQPage\",\n    \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\\\/\\\/glabridinchina.com\\\/what-ph-range-does-glabridin-require-in-cosmetic-formulations%ef%bc%9f\\\/\"\n    },\n    \"about\": {\n        \"@type\": \"ChemicalSubstance\",\n        \"name\": \"Glabridin\",\n        \"alternateName\": \"\\u5149\\u7518\\u8349\\u5b9a\"\n    },\n    \"publisher\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical\",\n        \"url\": \"https:\\\/\\\/glabridinchina.com\"\n    },\n    \"mainEntity\": [\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What pH range does glabridin require in cosmetic formulations?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Based on formulation experience and stability studies on polyphenolic compounds, a pH range of approximately 4.0\\u20135.5 is generally considered favorable for maintaining glabridin stability in cosmetic systems. pH 5.5\\u20136.5 is acceptable with reinforced antioxidant and chelation protection. Above pH 7.0, accelerated oxidative degradation occurs \\u2014 glabridin's phenolic hydroxyl groups deprotonate, increasing oxidative sensitivity and leading to active loss and color change. Always verify final pH after all cool-down additions are complete, not before.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What happens to glabridin above pH 7.0?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Above pH 7.0, glabridin's phenolic hydroxyl groups deprotonate more readily to form phenoxide anions, significantly increasing oxidative sensitivity and accelerating radical-mediated oxidative degradation. This process generates conjugated oxidation products, manifesting as progressive color deepening accompanied by active content loss. The degradation shows significant pH-dependent acceleration: above pH 7.0, stability decreases markedly and the system may show higher sensitivity to further pH changes.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What buffer system should I use for glabridin formulations?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Citric acid\\\/sodium citrate (effective buffering range pH 3.0\\u20136.2) and lactic acid\\\/sodium lactate (effective range pH 3.6\\u20135.8) are both well-suited for glabridin formulations. Both are cosmetically well-tolerated and compatible with COSMOS certification. Phosphate buffers offer weak metal chelation and lower oxidation protection compared to organic buffer systems. Avoid using co-actives that require strongly alkaline pH \\u2014 raw L-ascorbic acid (pH 2.5\\u20133.5) and retinol esters (pH 6.5\\u20137.5) both require pH conditions that conflict with glabridin's stability window.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Can glabridin be used in formulations above pH 6.5?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"pH 6.5\\u20137.0 is a marginal zone that carries elevated degradation risk. If the application requires pH above 6.5 \\u2014 for example, a gentle cleanser or a peptide-forward formula \\u2014 reinforce the antioxidant system (tocopherol at 0.3% or above), include metal chelation, and plan accelerated stability testing to monitor active loss and color change. Above pH 7.0, glabridin is not recommended. Select an alternative brightening active compatible with alkaline pH for those applications.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Why should pH be checked after all cool-down additions are complete?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Glabridin and many of its standard co-actives \\u2014 including niacinamide, tranexamic acid, and certain peptides \\u2014 can influence the final equilibrium pH of a buffered system upon addition during the cool-down phase. A base formula buffered to pH 5.5 before active addition may change after all actives are incorporated. If pH is only checked before active addition, the finished product may enter stability testing outside the intended range, with no opportunity for correction.\"\n            }\n        }\n    ]\n}<\/script>\n\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n  <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;500;600;700&family=Merriweather:ital,wght@0,400;0,700;1,400&display=swap\" rel=\"stylesheet\">\n\n  <style>\n    :root {\n      --color-bg:           #f9f9f7;\n      --color-surface:      #ffffff;\n      --color-border:       #e5e2d9;\n      --color-text:         #1c1c1a;\n      --color-text-muted:   #6a6760;\n      --color-accent:       #2d5a3d;\n      --color-accent-light: #edf4ef;\n      --color-accent-mid:   #4a7c5f;\n      --color-warn:         #7a4f1e;\n      --color-warn-light:   #fdf4eb;\n      --color-data-bg:      #f3f1ed;\n      --font-heading:     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   }\n    .callout.warning {\n      border-left-color: var(--color-warn); background: var(--color-warn-light);\n    }\n    .callout p { margin-bottom: 0; }\n    .callout p + p { margin-top: 8px; }\n\n    \/* \u2500\u2500 Decision tree \u2500\u2500 *\/\n    .decision-tree {\n      background: var(--color-data-bg); border: 1px solid var(--color-border);\n      border-radius: var(--radius); padding: 20px 24px; margin: 20px 0;\n      font-size: 14.5px; line-height: 1.8;\n    }\n    .decision-tree .dt-block {\n      margin-bottom: 16px; padding-bottom: 16px;\n      border-bottom: 1px solid var(--color-border);\n    }\n    .decision-tree .dt-block:last-child { margin-bottom: 0; padding-bottom: 0; border-bottom: none; }\n    .decision-tree .dt-question {\n      font-weight: 600; color: var(--color-text); margin-bottom: 6px;\n    }\n    .decision-tree .dt-answer { color: var(--color-text-muted); padding-left: 14px; }\n    .decision-tree .dt-answer span {\n      display: block; padding: 2px 0 2px 14px; position: relative;\n    }\n    .decision-tree .dt-answer span::before {\n      content: '\u2192'; position: absolute; left: 0; color: var(--color-accent); font-weight: 600;\n    }\n\n    \/* \u2500\u2500 Figures \u2500\u2500 *\/\n    .figure { margin: 24px 0 28px; }\n    .figure img {\n      width: 100%; max-width: 560px; display: block;\n      border: 1px solid var(--color-border); border-radius: var(--radius);\n    }\n    .figure figcaption {\n      margin-top: 8px; font-size: 13px; color: var(--color-text-muted);\n      line-height: 1.5; font-style: italic; max-width: 560px;\n    }\n\n    \/* \u2500\u2500 Related \u2500\u2500 *\/\n    .related-section { margin-top: 52px; padding-top: 28px; border-top: 1px solid var(--color-border); }\n    .related-section h2 {\n      font-family: var(--font-body); font-size: 12px; font-weight: 700;\n      margin-bottom: 14px; color: var(--color-text-muted); border: none; padding: 0;\n      text-transform: uppercase; letter-spacing: 0.07em;\n    }\n    .related-links { display: grid; gap: 8px; }\n    .related-link {\n      display: flex; align-items: center; gap: 12px; padding: 12px 14px;\n      background: var(--color-surface); border: 1px solid var(--color-border);\n      border-radius: var(--radius); text-decoration: none; color: var(--color-text);\n      font-size: 14px; transition: border-color 0.15s, background 0.15s;\n    }\n    .related-link:hover { border-color: var(--color-accent); background: var(--color-accent-light); }\n    .related-link-arrow { color: var(--color-accent); font-size: 16px; flex-shrink: 0; margin-left: auto; }\n\n    \/* \u2500\u2500 CTA \u2500\u2500 *\/\n    .cta-box {\n      margin-top: 36px; background: var(--color-accent); border-radius: var(--radius);\n      padding: 24px 28px; display: flex; align-items: center;\n      justify-content: space-between; gap: 20px; flex-wrap: wrap;\n    }\n    .cta-box-text { color: rgba(255,255,255,0.85); font-size: 14px; }\n    .cta-box-text strong {\n      color: #fff; display: block; font-size: 16px; margin-bottom: 3px;\n      font-family: var(--font-heading);\n    }\n    .cta-btn {\n      background: #fff; color: var(--color-accent); text-decoration: none;\n      font-weight: 700; font-size: 13px; padding: 9px 20px; border-radius: 4px;\n      white-space: nowrap; letter-spacing: 0.02em; flex-shrink: 0;\n    }\n\n    \/* \u2500\u2500 References \u2500\u2500 *\/\n    .references { margin-top: 44px; padding-top: 24px; border-top: 1px solid var(--color-border); }\n    .references h2 {\n      font-family: var(--font-body); font-size: 12px; font-weight: 700;\n      margin-bottom: 12px; color: var(--color-text-muted); border: none; padding: 0;\n      text-transform: uppercase; letter-spacing: 0.07em;\n    }\n    .references ol { padding-left: 18px; }\n    .references li { font-size: 13px; color: var(--color-text-muted); line-height: 1.6; margin-bottom: 7px; }\n    .references a { color: var(--color-accent); }\n\n    .article-footer {\n      margin-top: 36px; padding-top: 18px; border-top: 1px solid var(--color-border);\n      font-size: 12px; color: var(--color-text-muted); line-height: 1.6;\n    }\n  <\/style>\n<\/head>\n<body>\n\n\n\n  <div class=\"page-wrap\">\n\n    <header class=\"article-header\">\n      <div class=\"tag-row\">\n        <span class=\"tag\">\uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/span>\n        <span class=\"tag secondary\">\uae00\ub77c\ube0c\ub9ac\ub518<\/span>\n        <span class=\"tag secondary\">pH \uad00\ub9ac<\/span>\n      <\/div>\n\n      <p class=\"article-intro\">\ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c\uc5d0 \ub300\ud55c \uc81c\ud615 \uacbd\ud5d8\uacfc \uc548\uc815\uc131 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c, \uc57d 4.0\u20135.5\uc758 pH \ubc94\uc704\ub294 \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \uc77c\ubc18\uc801\uc73c\ub85c \uc720\ub9ac\ud55c \uac83\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4. \uc774 \uae00\uc5d0\uc11c\ub294 pH \uc694\uad6c \uc0ac\ud56d\uc758 \ud654\ud559\uc801 \uc6d0\ub9ac, \uc62c\ubc14\ub978 \uc644\ucda9 \uc2dc\uc2a4\ud15c\uc744 \uc120\ud0dd\ud558\uace0 \uac80\uc99d\ud558\ub294 \ubc29\ubc95, \uadf8\ub9ac\uace0 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 pH \ubc94\uc704\uc640 \uc77c\ubc18\uc801\uc778 \uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84\uacfc\uc758 \uc870\ud654\ub97c \uc774\ub8e8\ub294 \ubc29\ubc95\uc5d0 \ub300\ud574 \ub2e4\ub8f9\ub2c8\ub2e4.<\/p>\n      <div class=\"byline\">\n        <span><strong>\ud654\ud0dc \ubc14\uc774\uc624-\ud30c\uc778 \ucf00\ubbf8\uce7c<\/strong> \u2014 2008\ub144\ubd80\ud130 \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ud65c\uc131 \uc131\ubd84\uc744 \uc81c\uc870\ud574 \uc628<\/span>\n        <span style=\"color:var(--color-border)\">\u00b7<\/span>\n        <span>2026\ub144 \ubc1c\ud589<\/span>\n      <\/div>\n    <\/header>\n\n    <article class=\"article-body\">\n\n      <p>\ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c\uc5d0 \ub300\ud55c \uc81c\ud615 \uacbd\ud5d8\uacfc \uc548\uc815\uc131 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c, \uc57d 4.0\u20135.5\uc758 pH \ubc94\uc704\ub294 \ud654\uc7a5\ud488 \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud558\ub294 \ub370 \uc77c\ubc18\uc801\uc73c\ub85c \uc720\ub9ac\ud55c \uac83\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4. \uc774\ub294 \uc548\uc815\uc131 \uae30\ubc18 \uc694\uad6c \uc0ac\ud56d\uc785\ub2c8\ub2e4. \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \ud3f4\ub9ac\ud398\ub180 \uad6c\uc870\ub294 \uc5ec\ub7ec \ud398\ub180\uc131 \uc218\uc0b0\uae30(-OH)\ub97c \ud3ec\ud568\ud558\uace0 \uc788\uc73c\uba70, \uc774\ub294 \uc57d\uc0b0\uc131 \uc870\uac74\uc5d0\uc11c \uc591\uc131\uc790\ud654\ub41c \uc0c1\ud0dc\ub97c \uc720\uc9c0\ud558\uc5ec \ubd84\uc790\ub97c \uac00\uc7a5 \uc548\uc815\ud558\uac8c \ub9cc\ub4ed\ub2c8\ub2e4. \ud658\uacbd\uc774 \uc911\uc131 \ub610\ub294 \uc54c\uce7c\ub9ac\uc131 pH 6.5 \uc774\uc0c1\uc73c\ub85c \uc811\uadfc\ud568\uc5d0 \ub530\ub77c \ud398\ub180\uc131 \uc218\uc0b0\uae30\ub294 \ud0c8\uc591\uc131\uc790\ud654\ub418\uae30 \uc2dc\uc791\ud558\uc5ec \uc0b0\ud654 \ubcc0\uc0c9 \ubc0f \ubd84\ud574\uc5d0 \ub300\ud55c \ubbfc\uac10\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4.<\/p>\n\n      <h2>pH \uc694\uad6c \uc0ac\ud56d\uc758 \ud654\ud559\uc801 \uc6d0\ub9ac<\/h2>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uace0\ub9ac \uad6c\uc870\uc758 2\u2032 \ubc0f 4\u2032 \uc704\uce58\uc5d0 \ub450 \uac1c\uc758 \ud398\ub180\uc131 \uc218\uc0b0\uae30\ub97c \ud3ec\ud568\ud558\ub294 \ud3f4\ub9ac\ud398\ub180\uc131 \uc774\uc18c\ud50c\ub77c\ubc18 \ud654\ud569\ubb3c\uc785\ub2c8\ub2e4. \uc774 \uadf8\ub8f9\ub4e4\uc740 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c \ud65c\uc131\uc5d0 \uc911\uc694\ud558\uba70, pH\uc5d0 \uc758\ud574 \uc720\ub3c4\ub418\ub294 \uc0b0\ud654 \ubd84\ud574\uc758 \uc8fc\uc694 \ubd80\uc704\uc785\ub2c8\ub2e4.<\/p>\n\n      <p>pH 7.0 \uc774\uc0c1\uc5d0\uc11c\ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \ud398\ub180\uc131 \uc218\uc0b0\uae30 \uadf8\ub8f9\uc774 \ub354 \uc27d\uac8c \ud0c8\uc591\uc131\uc790\ud654\ub418\uc5b4 \ud398\ub179\uc0ac\uc774\ub4dc \uc74c\uc774\uc628\uc744 \ud615\uc131\ud558\uba70, \uc774\ub294 \uc0b0\ud654 \ubbfc\uac10\uc131\uc744 \ud06c\uac8c \uc99d\uac00\uc2dc\ud0a4\uace0 \ub77c\ub514\uce7c \ub9e4\uac1c \uc0b0\ud654 \ubd84\ud574\ub97c \uac00\uc18d\ud654\ud569\ub2c8\ub2e4. \uc774 \uacfc\uc815\uc740 \uacf5\uc561 \uc0b0\ud654 \uc0dd\uc131\ubb3c\uc744 \uc0dd\uc131\ud558\uba70, \ud65c\uc131 \ud568\ub7c9 \uc190\uc2e4\uacfc \ud568\uaed8 \uc810\uc9c4\uc801\uc778 \uc0c9\uc0c1 \uc2ec\ud654\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4.<\/p>\n\n      <p>\ubd84\ud574\ub294 \uc0c1\ub2f9\ud55c pH \uc758\uc874\uc801 \uac00\uc18d\uc744 \ubcf4\uc785\ub2c8\ub2e4. pH 7.0 \uc774\uc0c1\uc5d0\uc11c\ub294 \uc2dc\uc2a4\ud15c \uc548\uc815\uc131\uc774 \ud604\uc800\ud788 \uac10\uc18c\ud558\uba70, \uc81c\ud615\uc740 \ucd94\uac00\uc801\uc778 pH \ubcc0\ud654\uc5d0 \ub354 \ubbfc\uac10\ud574\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac00\uc18d \uc548\uc815\uc131 \uc870\uac74(ICH Q1A(R2), 40\u00b0C \/ 75% RH) \ud558\uc5d0\uc11c pH 7.5\uc758 \uc81c\ud615\uc740 \uc77c\ubc18\uc801\uc73c\ub85c pH 5.5\uc758 \uc81c\ud615\ubcf4\ub2e4 \ub0ae\uc740 \uc548\uc815\uc131\uc744 \ubcf4\uc785\ub2c8\ub2e4.<\/p>\n\n      <p>\ubc1c\ud45c\ub41c \uc548\uc815\uc131 \ub370\uc774\ud130(Ao et al., <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, 2010, DOI: 10.1177\/1934578X1000501214)\uc5d0 \uae30\ub85d\ub41c pH \uc548\uc815\uc131 \uac70\ub3d9\uc740 \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc0b0\uc131 \ubc0f \uc911\uc131 \uc870\uac74\uc5d0\uc11c \uc548\uc815\ud558\uba70, \uc54c\uce7c\ub9ac\uc131 \uc870\uac74\uc5d0\uc11c \uc0c1\ub2f9\ud55c \ubd84\ud574\uac00 \ubc1c\uc0dd\ud55c\ub2e4\ub294 \uac83\uc744 \ubcf4\uc5ec\uc8fc\uba70, \uc774\ub294 \uc774\ub7ec\ud55c \uae30\uacc4\ub860\uc801 \uc774\ud574\uc640 \uc77c\uce58\ud569\ub2c8\ub2e4.<\/p>\n\n      <h2>pH \uc548\uc815\uc131 \ubc94\uc704<\/h2>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>pH \ubc94\uc704<\/th>\n              <th>\uc548\uc815<\/th>\n              <th>\uc2e4\uc81c\uc801 \uc758\ubbf8<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>4.0\u20135.5<\/strong><\/td>\n              <td><strong>\uc720\ub9ac\ud55c<\/strong><\/td>\n              <td>\ub300\ubd80\ubd84\uc758 \ub9ac\ube0c\uc628(leave-on) \uc81c\ud488\uc5d0 \ub300\ud55c \ubaa9\ud45c \ubc94\uc704<\/td>\n            <\/tr>\n            <tr>\n              <td>5.5\u20136.5<\/td>\n              <td>\uc88b\uc74c<\/td>\n              <td>\ud5c8\uc6a9 \uac00\ub2a5; \ud56d\uc0b0\ud654 \ubc0f \ud0ac\ub808\uc774\ud2b8 \uc2dc\uc2a4\ud15c \uac15\ud654<\/td>\n            <\/tr>\n            <tr>\n              <td>6.5\u20137.0<\/td>\n              <td>\uacbd\uacc4<\/td>\n              <td>\ub192\uc740 \uc704\ud5d8; \uc0c1\uc6a9\ud654 \uc804\uc5d0 \uac00\uc18d \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8 \uc218\ud589<\/td>\n            <\/tr>\n            <tr>\n              <td>&gt;7.0<\/td>\n              <td>\ub098\uc068<\/td>\n              <td>\uc54c\uce7c\ub9ac\uc131 \uc870\uac74\uc5d0\uc11c\uc758 \uac00\uc18d \uc0b0\ud654 \ubd84\ud574, \uc810\uc9c4\uc801\uc778 \uc0c9\uc0c1 \ubcc0\ud654 \u2014 \ud53c\ud574\uc57c \ud568<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_pH_stability-1.png\"\n             alt=\"pH 1\u201313\uc5d0 \ub530\ub978 \uae00\ub77c\ube0c\ub9ac\ub518 \ub18d\ub3c4\ub97c \ubcf4\uc5ec\uc8fc\ub294 \uace1\uc120 \ucc28\ud2b8, pH 1\u20136\uc5d0\uc11c \uc548\uc815\uc801\uc778 \ud3c9\ud0c4 \uad6c\uac04, pH 7 \uc774\uc0c1\uc5d0\uc11c \uae09\uaca9\ud55c \uac10\uc18c\">\n        <figcaption>\uadf8\ub9bc 1 \u2014 pH\uac00 \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5. \ub18d\ub3c4\ub294 pH 1\u20136\uc5d0\uc11c \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ub418\ub2e4\uac00 pH 7 \uc774\uc0c1\uc5d0\uc11c \uae09\uaca9\ud788 \uac10\uc18c\ud569\ub2c8\ub2e4. pH 13\uc5d0\uc11c\ub294 \ub18d\ub3c4\uac00 \uc57d 7 \u00b5g\/mL\ub85c \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. \ub370\uc774\ud130: Ao et al., <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, 2010.<\/figcaption>\n      <\/figure>\n\n      <p>\ub300\ubd80\ubd84\uc758 \ub9ac\ube0c\uc628 \ube0c\ub77c\uc774\ud2b8\ub2dd \uc81c\ud615(\uc138\ub7fc, \uc5d0\uba40\uc83c, \ud1a0\ub108, \uc5d0\uc13c\uc2a4)\uc758 \uacbd\uc6b0, pH 4.5\u20135.5\ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc5d0 \uae30\uc220\uc801\uc73c\ub85c \uc720\ub9ac\ud558\uace0 \ud654\uc7a5\ud488\uc801\uc73c\ub85c \uc801\ud569\ud569\ub2c8\ub2e4. \uc774\ub294 \uac74\uac15\ud55c \ud53c\ubd80 \ud45c\uba74 pH(4.5\u20135.5)\uc758 \uc0dd\ub9ac\uc801 \ubc94\uc704 \ub0b4\uc5d0 \uc788\uc5b4 \ud65c\uc131 \uc548\uc815\uc131\uacfc \ud568\uaed8 \uc7a5\ubcbd \uae30\ub2a5 \ubc0f \ubbf8\uc0dd\ubb3c \uade0\ud615\uc744 \uc9c0\uc6d0\ud569\ub2c8\ub2e4.<\/p>\n\n      <h2>\uc644\ucda9 \uc2dc\uc2a4\ud15c \uc120\ud0dd<\/h2>\n\n      <p>\uc81c\ud615\uc758 pH\ub294 \ubcf4\uad00 \uc911\uc5d0 \ubcc0\ub3d9\ub420 \uc218 \uc788\uc73c\uba70, \ud2b9\ud788 \uc5d0\uba40\uc83c\uc758 \uacbd\uc6b0 \uc218\uc131\uc0c1 \ub0b4 \ubc0f \uc624\uc77c-\ubb3c \uacc4\uba74\uc5d0\uc11c\uc758 \ud654\ud559 \ubc18\uc751\uc774 \uc2dc\uac04\uc774 \uc9c0\ub0a8\uc5d0 \ub530\ub77c \uc2dc\uc2a4\ud15c\uc744 \ubcc0\uacbd\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c, \uacf5\ub3d9 \uc131\ubd84\uc758 \uc0b0\uc131 \ub610\ub294 \uc54c\uce7c\ub9ac\uc131 \ubd84\ud574\ub294 \uc804\uccb4 \ud3c9\ud615\uc744 \ub354\uc6b1 \uc774\ub3d9\uc2dc\ud0ac \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc801\uc808\ud558\uac8c \uc644\ucda9\ub41c \uc218\uc131\uc0c1\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n      <h3>\uad8c\uc7a5 \uc644\ucda9 \uc2dc\uc2a4\ud15c<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc644\ucda9 \uc2dc\uc2a4\ud15c<\/th>\n              <th>\uc720\ud6a8 pH \ubc94\uc704<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>\uad6c\uc5f0\uc0b0 \/ \uad6c\uc5f0\uc0b0\ub098\ud2b8\ub968<\/strong><\/td>\n              <td>3.0\u20136.2<\/td>\n              <td>\ub2e4\uc6a9\ub3c4; \ud654\uc7a5\ud488\uc73c\ub85c \uc798 \ud5c8\uc6a9\ub428; \uae08\uc18d \uc774\uc628\uc5d0 \ub300\ud55c \uc57d\ud55c \ud0ac\ub808\uc774\ud2b8 \ud6a8\uacfc<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc816\uc0b0 \/ \uc816\uc0b0\ub098\ud2b8\ub968<\/td>\n              <td>3.6\u20135.8<\/td>\n              <td>\ud53c\ubd80\uc640 \ub3d9\uc77c; \uc7a5\ubcbd \uae30\ub2a5 \uc9c0\uc6d0; NMF \uad6c\uc131 \uc694\uc18c<\/td>\n            <\/tr>\n            <tr>\n              <td>\uae00\ub8e8\ucf54\ub178\ub77d\ud1a4 \/ \uae00\ub8e8\ucf58\uc0b0\ub098\ud2b8\ub968<\/td>\n              <td>3.5\u20136.0<\/td>\n              <td>PHA; \uc57d\ud55c \uac01\uc9c8 \uc81c\uac70\uc81c; \ub2e4\uae30\ub2a5\uc801 \uc774\uc810 \ucd94\uac00<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <h3>\uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud568\uaed8 \ud53c\ud574\uc57c \ud560 \uc2dc\uc2a4\ud15c<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc644\ucda9\uc561 \/ \uc2dc\uc2a4\ud15c<\/th>\n              <th>\uc6b0\ub824 \uc0ac\ud56d<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uc778\uc0b0\uc5fc \uc644\ucda9\uc561<\/td>\n              <td>\uc57d\ud55c \uae08\uc18d \ud0ac\ub808\uc774\ud2b8\ud654; \uc720\uae30 \uc644\ucda9 \uc2dc\uc2a4\ud15c\uc5d0 \ube44\ud574 \ub0ae\uc740 \uc0b0\ud654 \ubc29\uc9c0<\/td>\n            <\/tr>\n            <tr>\n              <td>\ud0c4\uc0b0\uc218\uc18c\ub098\ud2b8\ub968\/\ud0c4\uc0b0\ub098\ud2b8\ub968<\/td>\n              <td>\uc54c\uce7c\ub9ac\uc131 \ubc94\uc704; \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uacfc \ube44\ud638\ud658\uc131<\/td>\n            <\/tr>\n            <tr>\n              <td>\ud2b8\ub9ac\uc5d0\ud0c4\uc62c\uc544\ubbfc(TEA) \uc870\uc815<\/td>\n              <td>\uc644\ucda9\uc561\uc774 \uc544\ub2d8; \uc57d\ud55c pH \uc548\uc815\uc131 \uc81c\uc5b4<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>\uad6c\uc5f0\uc0b0\/\uad6c\uc5f0\uc0b0\ub098\ud2b8\ub968\uc740 \uac00\uc7a5 \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub418\uace0 \uac00\uc7a5 \uc2e4\uc6a9\uc801\uc778 \uc120\ud0dd\uc785\ub2c8\ub2e4. \uae08\uc18d \uc774\uc628\uc5d0 \ub300\ud55c \uc644\ub9cc\ud55c \ud0ac\ub808\uc774\ud2b8 \ud6a8\uacfc\ub294 pH \uc644\ucda9\uacfc \ud568\uaed8 \ubd80\uac00\uc801\uc778 \uc774\uc810\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc989, \uc81c\ud615\uc5d0\uc11c EDTA \ub610\ub294 \ud53c\ud2b8\uc0b0\ub098\ud2b8\ub968\uc758 \ud0ac\ub808\uc774\ud2b8 \ubd80\ub2f4\uc744 \uc904\uc5ec\uc90d\ub2c8\ub2e4.<\/p>\n\n      <h2>pH \uac80\uc99d \uaddc\uce59<\/h2>\n\n      <p><strong>\ucd5c\uc885 pH\ub294 \uc644\uc804\ud55c \ub0c9\uac01 \ucca8\uac00 \ubc0f \ud3c9\ud615 \ud6c4 \ud655\uc778\ud574\uc57c \ud569\ub2c8\ub2e4.<\/strong><\/p>\n\n      <p>\uc774\uac83\uc740 \uc0dd\uc0b0\uc5d0\uc11c \uac00\uc7a5 \ud754\ud558\uac8c \uc0dd\ub7b5\ub418\ub294 pH \uad00\ub9ac \ub2e8\uacc4\uc785\ub2c8\ub2e4. \uc774\uac83\uc774 \uc911\uc694\ud55c \uc774\uc720:<\/p>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ub2c8\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc, \ud2b8\ub77c\ub125\uc0bc\uc0b0, \ud2b9\uc815 \ud3a9\ud0c0\uc774\ub4dc\ub97c \ud3ec\ud568\ud55c \ub9ce\uc740 \ud45c\uc900 \uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84\uc740 \ub0c9\uac01 \ub2e8\uacc4 \ub3d9\uc548 \ucca8\uac00 \uc2dc \uc644\ucda9 \uc2dc\uc2a4\ud15c\uc758 \ucd5c\uc885 \ud3c9\ud615 pH\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud65c\uc131 \ucca8\uac00 \uc804\uc5d0 pH 5.5\ub85c \uc644\ucda9\ub41c \uae30\ubcf8 \uc81c\ud615\uc740 \ubaa8\ub4e0 \ud65c\uc131\uc774 \ud1b5\ud569\ub41c \ud6c4 \ubcc0\uacbd\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud56d\uc0c1 \ubaa8\ub4e0 \ud65c\uc131\uc774 \ud1b5\ud569\ub41c \ud6c4 \ucd5c\uc885 pH \uc218\uc815\uc744 \uc704\ud574 \uad6c\uc5f0\uc0b0 \uc6a9\uc561\uc744 \ub530\ub85c \ubcf4\uad00\ud558\uc2ed\uc2dc\uc624.<\/p>\n\n      <div class=\"callout warning\">\n        <p><strong>\uc77c\ubc18\uc801\uc778 \uc0dd\uc0b0 \uc624\ub958:<\/strong> \ub0c9\uac01 \ucca8\uac00 \uc804\uc5d0\ub9cc pH \uac80\uc0ac\ub97c \uc218\ud589\ud558\uba74 \ubaa8\ub4e0 \ubcc0\ud654\uac00 \uac10\uc9c0\ub418\uc9c0 \uc54a\uc544 \uc81c\ud615 \ub2f4\ub2f9\uc790\uac00 \ubaa8\ub974\ub294 \uc0ac\uc774\uc5d0 \uc81c\ud488\uc774 \uc758\ub3c4\ub41c \uc548\uc815\uc131 \ubc94\uc704\ub97c \ubc97\uc5b4\ub098 \ucd9c\ud558\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <h3>\uc2e4\uc6a9\uc801\uc778 SOP \ud504\ub85c\ud1a0\ucf5c<\/h3>\n\n      <ol>\n        <li>\uc720\ud654 \uc804\uc5d0 \uc218\uc131\uc0c1\uc744 \ubaa9\ud45c pH(\uc77c\ubc18\uc801\uc73c\ub85c 4.5\u20135.2)\ub85c \uc644\ucda9<\/li>\n        <li>\ud45c\uc900 \uc628\ub3c4\uc5d0\uc11c \uc644\uc804 \uc720\ud654<\/li>\n        <li>\ub0c9\uac01 \uc2dc\uc791; 50\u00b0C \uc774\ud558\uc5d0\uc11c \uc544\ub798 \uc21c\uc11c\ub300\ub85c \ubaa8\ub4e0 \ud65c\uc131 \uc131\ubd84 \ucca8\uac00<\/li>\n        <li>\uc644\uc804\ud788 \ud3c9\ud615\ud654\ub41c \uc870\uac74 \ud558\uc5d0\uc11c 30\u201335\u00b0C\uc5d0\uc11c pH \uce21\uc815<\/li>\n        <li>\uc81c\ud615 \uc124\uacc4\uc5d0 \ub530\ub77c \uc801\uc808\ud55c \uc0b0 \ub610\ub294 \uc5fc\uae30 \uc6a9\uc561\uc744 \uc0ac\uc6a9\ud558\uc5ec \ud544\uc694\ud55c \uacbd\uc6b0 \ubaa9\ud45c \uc0ac\uc591 \ubc94\uc704\ub85c pH \uc870\uc815<\/li>\n        <li>\uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\ub85c \ub118\uc5b4\uac00\uae30 \uc804 \ubc30\uce58 \uae30\ub85d\uc5d0 \ucd5c\uc885 pH \uae30\ub85d<\/li>\n      <\/ol>\n\n      <h2>pH \ubc0f \uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84 \ud638\ud658\uc131<\/h2>\n\n      <p>pH \uc120\ud0dd\uc740 \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc804\uccb4 \ud65c\uc131 \uc2dc\uc2a4\ud15c\uc758 \ud638\ud658\uc131\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uba87 \uac00\uc9c0 \uace0\ubd80\uac00\uac00\uce58 \ubbf8\ubc31 \uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84\uc740 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \ubc94\uc704\uc640 \uc870\ud654\ub418\uc5b4\uc57c \ud558\ub294 pH \uc694\uad6c \uc0ac\ud56d\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84<\/th>\n              <th>\ucd5c\uc801 pH \ubc94\uc704<\/th>\n              <th>\uae00\ub77c\ube0c\ub9ac\ub518\uacfc \ud638\ud658\ub429\ub2c8\uae4c?<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\ub098\uc774\uc544\uc2e0\uc544\ubbf8\ub4dc<\/td>\n              <td>5.0\u20137.0<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 5.0\u20136.0\uc5d0\uc11c \uacb9\uce68<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\ud2b8\ub77c\ub125\uc0bc\uc0b0 (TXA)<\/td>\n              <td>4.5\u20136.5<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 \uc644\uc804 \uacb9\uce68<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\uc544\uc2a4\ucf54\ube4c \uae00\ub8e8\ucf54\uc0ac\uc774\ub4dc (AA-2G)<\/td>\n              <td>5.0\u20137.0<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 5.0\u20136.0\uc5d0\uc11c \uacb9\uce68<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\ub9c8\uadf8\ub124\uc298 \uc544\uc2a4\ucf54\ube4c \ud3ec\uc2a4\ud398\uc774\ud2b8 (MAP)<\/td>\n              <td>5.5\u20137.0<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 5.5\u20136.5\uc5d0\uc11c \uacb9\uce68 (\ucc38\uace0: MAP \uc548\uc815\uc131 \ubc0f \uc6a9\ud574\ub3c4\ub294 pH 5.5 \uc774\ud558\uc5d0\uc11c \uac10\uc18c\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4)<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\ub514\ud3ec\ud0c0\uc298 \uae00\ub9ac\uc2dc\ub9ac\uc81c\uc774\ud2b8 (DPG)<\/td>\n              <td>4.5\u20137.5<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 \uc644\uc804 \uacb9\uce68<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\uc5d1\ud1a0\uc778<\/td>\n              <td>4.0\u20138.0<\/td>\n              <td><span class=\"compat-yes\">\u2705 \uc608 \u2014 \uc644\uc804 \uacb9\uce68<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\uc6d0\ub8cc L-\uc544\uc2a4\ucf54\ub974\ube0c\uc0b0<\/td>\n              <td>2.5\u20133.5<\/td>\n              <td><span class=\"compat-no\">\u274c \uc548\ub428 \u2014 pH \ucda9\ub3cc; pH 2.5\u20133.5\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uc0b0\ud654 \uc704\ud5d8 \uc99d\uac00<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>\ub808\ud2f0\ub180 \uc5d0\uc2a4\ud130<\/td>\n              <td>6.5\u20137.5<\/td>\n              <td><span class=\"compat-no\">\u274c \uc548\ub428 \u2014 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uc548\uc815 \ubc94\uc704\ubcf4\ub2e4 \ub192\uc740 pH \ud544\uc694<\/span><\/td>\n            <\/tr>\n            <tr>\n              <td>AHA (\uae00\ub9ac\ucf5c\uc0b0, \uc816\uc0b0 \uace0\ub18d\ub3c4)<\/td>\n              <td>3.0\u20134.0<\/td>\n              <td><span class=\"compat-marginal\">\u26a0\ufe0f \uacbd\uacc4 \u2014 \ub300\ubd80\ubd84\uc758 \uae00\ub77c\ube0c\ub9ac\ub518 \uc81c\ud615\uc5d0 \ub108\ubb34 \uc0b0\uc131; PHA \uc0ac\uc6a9 \uad8c\uc7a5<\/span><\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uc758 pH \ubc94\uc704\uc640 \ud638\ud658\ub418\ub294 \uac00\uc7a5 \uc2e4\uc6a9\uc801\uc778 \ube0c\ub77c\uc774\ud2b8\ub2dd \uacf5\ub3d9 \ud65c\uc131 \uc2a4\ud0dd\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4: <strong>\uae00\ub77c\ube0c\ub9ac\ub518 + \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc + TXA + AA-2G<\/strong>, \ubaa8\ub450 pH 5.0\u20136.0 \ubc94\uc704\uc5d0\uc11c \uae30\ub2a5\ud569\ub2c8\ub2e4. \uc774 \uc870\ud569\uc740 \uc0c1\ub958 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c(\uae00\ub77c\ube0c\ub9ac\ub518), \uba5c\ub77c\ub178\uc81c\ub124\uc2dc\uc2a4\uc640 \uad00\ub828\ub41c \uc5fc\uc99d \ubc0f \ud50c\ub77c\uc2a4\ubbfc \uad00\ub828 \uc2e0\ud638 \uc870\uc808(\ud2b8\ub77c\ub125\uc0bc\uc0b0), \uba5c\ub77c\ub178\uc19c \uc804\ub2ec \ucc28\ub2e8(\ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc), \ud56d\uc0b0\ud654 \ub9e4\uac1c \uba5c\ub77c\ub2cc \ud615\uc131 \ubc0f \uc0b0\ud654 \uacfc\uc815 \uc5b5\uc81c(AA-2G) \u2014 \uc0c9\uc18c \uce68\ucc29 \uacbd\ub85c\uc5d0\uc11c \ub124 \uac00\uc9c0 \uc0c1\ud638 \ubcf4\uc644\uc801\uc778 \ucc28\ub2e8 \uc9c0\uc810\uc744 \uc81c\uacf5\ud558\uba70, \uc57d\uc0b0\uc131\uc5d0\uc11c \uc911\uc131\uc5d0 \uac00\uae4c\uc6b4 \ub3d9\uc77c\ud55c pH \ubc94\uc704 \ub0b4\uc5d0\uc11c \uad11\ubc94\uc704\ud558\uac8c \ud638\ud658\ub429\ub2c8\ub2e4.<\/p>\n\n      <h2>\uc2e4\uc6a9\uc801\uc778 \uc81c\ud615 \uacb0\uc815 \ud2b8\ub9ac<\/h2>\n\n      <div class=\"decision-tree\">\n        <div class=\"dt-block\">\n          <div class=\"dt-question\">\uc801\uc6a9 \uc81c\ud488\uc774 \ub9ac\ube0c\uc628 \ube0c\ub77c\uc774\ud2b8\ub2dd(\uc138\ub7fc, \uc5d0\uba40\uc83c, \ud1a0\ub108)\uc778\uac00\uc694?<\/div>\n          <div class=\"dt-answer\">\n            <span>\ubaa9\ud45c pH\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uc57d\uc0b0\uc131 \ubc94\uc704(\uc57d pH 4.5\u20135.5)\uc785\ub2c8\ub2e4.<\/span>\n            <span>\uad6c\uc5f0\uc0b0\/\uad6c\uc5f0\uc0b0\ub098\ud2b8\ub968\uc73c\ub85c \uc644\ucda9<\/span>\n            <span>\ucd5c\uc885 pH\ub294 \uc644\uc804 \ub0c9\uac01 \ucca8\uac00 \ubc0f \ud3c9\ud615 \ud6c4 \ud655\uc778\ud574\uc57c \ud569\ub2c8\ub2e4.<\/span>\n          <\/div>\n        <\/div>\n        <div class=\"dt-block\">\n          <div class=\"dt-question\">\uadc0\ud558\uc758 \uc81c\ud615\uc5d0 \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc \ubc0f\/\ub610\ub294 TXA\uac00 \ud3ec\ud568\ub418\uc5b4 \uc788\uc2b5\ub2c8\uae4c?<\/div>\n          <div class=\"dt-answer\">\n            <span>\uc720\ud654 \uc804\uc5d0 \ubca0\uc774\uc2a4 \uc81c\ud615\uc744 \uc57d\uc0b0\uc131 pH(4.8\u20135.0)\ub85c \uc644\ucda9\ud558\uc2ed\uc2dc\uc624.<\/span>\n            <span>\uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84 \ud1b5\ud569 \ud6c4 pH \ud3b8\ucc28\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/span>\n            <span>\ucd5c\uc885 pH \uc870\uc815\uc744 \uc704\ud574 \uad6c\uc5f0\uc0b0 \uc6a9\uc561\uc744 \ub530\ub85c \ubcf4\uad00\ud558\uc2ed\uc2dc\uc624.<\/span>\n          <\/div>\n        <\/div>\n        <div class=\"dt-block\">\n          <div class=\"dt-question\">\uadc0\ud558\uc758 \uc81c\ud488\uc740 \ud5f9\uad7c\uc6a9 \ub610\ub294 \uc911\uc131(\uc608: \uc21c\ud55c \ud074\ub80c\uc800)\uc785\ub2c8\uae4c?<\/div>\n          <div class=\"dt-answer\">\n            <span>pH 6.0\u20136.5\ub97c \uc0ac\uc6a9\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4 \u2014 \ud56d\uc0b0\ud654\uc81c + \ud0ac\ub808\uc774\ud2b8 \uac15\ud654<\/span>\n            <span>\uac00\uc18d \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\ub97c \uc2e4\ud589\ud558\uace0 \uc0c9\uc0c1 \ubcc0\ud654\ub97c \uba74\ubc00\ud788 \ubaa8\ub2c8\ud130\ub9c1\ud558\uc2ed\uc2dc\uc624.<\/span>\n            <span>pH\uac00 6.5\ub97c \ucd08\uacfc\ud574\uc57c \ud558\ub294 \uacbd\uc6b0, \ub300\uccb4 \ubbf8\ubc31 \ud65c\uc131 \uc131\ubd84\uc744 \ud3c9\uac00\ud558\uc2ed\uc2dc\uc624.<\/span>\n          <\/div>\n        <\/div>\n        <div class=\"dt-block\">\n          <div class=\"dt-question\">\uadc0\ud558\uc758 \uc81c\ud615\uc5d0 pH &gt; 7.0\uc774 \ud544\uc694\ud569\ub2c8\uae4c(\uc608: \ub808\ud2f0\ub180, \ud2b9\uc815 \ud3a9\ud0c0\uc774\ub4dc)?<\/div>\n          <div class=\"dt-answer\">\n            <span>\uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc774 \uc2dc\uc2a4\ud15c\uc5d0 \uc801\ud569\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/span>\n            <span>pH \ud638\ud658 \ub300\uc548\uc73c\ub85c \ud2b8\ub77c\ub125\uc0bc\uc0b0 \ub610\ub294 \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc\ub97c \uace0\ub824\ud558\uc2ed\uc2dc\uc624.<\/span>\n          <\/div>\n        <\/div>\n      <\/div>\n\n      <div class=\"callout\">\n        <p>\ubaa8\ub4e0 \ubc30\uce58\uc5d0\ub294 COA, TDS \ubc0f SDS\/MSDS\uac00 \ud568\uaed8 \uc81c\uacf5\ub429\ub2c8\ub2e4. \ucd94\uac00 \ud14c\uc2a4\ud2b8\ub294 \uc694\uccad \uc2dc \uac00\ub2a5\ud569\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <!-- Related -->\n      <div class=\"related-section\">\n        <h2>\uad00\ub828 \uc790\ub8cc<\/h2>\n        <div class=\"related-links\">\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/glabridin\/\">\n            <span>\ud654\uc7a5\ud488 \uc81c\ud615\uc744 \uc704\ud55c \uae00\ub77c\ube0c\ub9ac\ub518 \uac00\uc774\ub4dc \u2014 \uc644\uc804 \uae30\uc220 \ucc38\uc870<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\uc804\uccb4 \uc548\uc815\uc131 \ub370\uc774\ud130, \ub4f1\uae09 \ub9e4\ud2b8\ub9ad\uc2a4 \ubc0f \uc81c\ud615 \ud504\ub85c\ud1a0\ucf5c<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/why-does-glabridin-discolor-in-emulsions-huatai-bio-fine-chemical\/\">\n            <span>\uc5d0\uba40\uc83c\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \ubcc0\uc0c9\ub418\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00\uc694?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">pH \uc720\ubc1c \uc0b0\ud654 \ubd84\ud574\ub97c \ud3ec\ud568\ud55c \uadfc\ubcf8 \uc6d0\uc778 \ubd84\uc11d<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/how-to-stabilize-glabridin-in-cosmetic-formulations\/\">\n            <span>\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc548\uc815\ud654\ud558\ub294 \ubc29\ubc95\uc740 \ubb34\uc5c7\uc785\ub2c8\uae4c?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">4\uac00\uc9c0 \uc81c\uc5b4 \uc548\uc815\ud654 \ud504\ub85c\ud1a0\ucf5c\uc744 \uc644\ub8cc\ud558\uc2ed\uc2dc\uc624.<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/can-glabridin-be-used-in-sensitive-skin-products\/\">\n            <span>\ubbfc\uac10\uc131 \ud53c\ubd80 \uc81c\ud488\uc5d0 \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc0ac\uc6a9\ud560 \uc218 \uc788\ub098\uc694?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">\ubbfc\uac10\uc131 \ubc0f \ubc18\uc751\uc131 \ud53c\ubd80\ub97c \uc704\ud55c \uc81c\ud615 \ub514\uc790\uc778<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n        <\/div>\n      <\/div>\n\n      <!-- CTA -->\n      <div class=\"cta-box\">\n        <div class=\"cta-box-text\">\n          <strong>\uc0d8\ud50c, COA \ub610\ub294 \uae30\uc220 \uc0c1\ub2f4 \uc694\uccad<\/strong>\n          glabridinchina.com \u00b7 jelly@huataibio.com \u00b7 +86 17868678161\n        <\/div>\n        <a class=\"cta-btn\" href=\"https:\/\/glabridinchina.com\/ko\/product-tag\/\">\ubb38\uc758\ud558\uae30 \u2192<\/a>\n      <\/div>\n\n      <!-- References -->\n      <div class=\"references\">\n        <h2>\ucc38\uace0 \uc790\ub8cc<\/h2>\n        <ol>\n          <li>Ao M, Shi Y, Cui Y, Guo W, Wang J, Yu L. \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc694\uc778. <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, Vol. 5(12), 1907\u20131912, 2010. DOI: 10.1177\/1934578X1000501214. PMID: 21299118.<\/li>\n          <li>Yokota T, Nishio H, Kubota Y, Mizoguchi M. \uac10\ucd08 \ucd94\ucd9c\ubb3c\uc5d0\uc11c \ucd94\ucd9c\ud55c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc0f \uc5fc\uc99d \uc5b5\uc81c \ud6a8\uacfc. <em>Pigment Cell Research<\/em>, 11(6), 355\u2013361, 1998. DOI: 10.1111\/j.1600-0749.1998.tb00494.x.<\/li>\n          <li>ICH Q1A(R2): \uc2e0\uaddc \uc758\uc57d\ud488 \uc6d0\ub8cc \ubc0f \uc644\uc81c\ud488\uc758 \uc548\uc815\uc131 \uc2dc\ud5d8. \uad6d\uc81c\uc758\uc57d\ud488\uaddc\uc81c\uc870\ud654\uc704\uc6d0\ud68c, 2003.<\/li>\n        <\/ol>\n      <\/div>\n\n      <div class=\"article-footer\">\n        <p>\uc804\ubb38 \ud654\uc7a5\ud488 \uc81c\ud615 \uac1c\ubc1c\uc790 \ubc0f \uc5f0\uad6c\uac1c\ubc1c \ub2f4\ub2f9\uc790\ub97c \uc704\ud55c \uc790\ub8cc\uc785\ub2c8\ub2e4. \uaddc\uc81c \uad00\ub828 \uc870\uc5b8\uc744 \uad6c\uc131\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<br>\n        \ubc1c\ud589 2026\ub144 \u2014 Huatai Bio-Fine Chemical, Xi'an, Shaanxi, China.<\/p>\n      <\/div>\n\n    <\/article>\n  <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>FAQ Glabridin pH \uad00\ub9ac \uc81c\ud615 \uacbd\ud5d8 \ubc0f \ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c \uc548\uc815\uc131 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c, \uc57d 4.0\u20135.5\uc758 pH \ubc94\uc704\uac00 \uc77c\ubc18\uc801\uc73c\ub85c \uc720\ub9ac\ud55c \uac83\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4\u2026<\/p>","protected":false},"author":8,"featured_media":5794,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[414],"tags":[],"class_list":["post-14105","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-troubleshooting-faq"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What pH Range Does Glabridin Require in Cosmetic Formulations? | Huatai Bio-Fine Chemical<\/title>\n<meta name=\"description\" content=\"Glabridin requires a mildly acidic pH of approximately 4.0\u20135.5 for optimal stability in cosmetic formulations. 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