{"id":14047,"date":"2026-06-05T01:48:34","date_gmt":"2026-06-05T01:48:34","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=14047"},"modified":"2026-06-05T02:30:02","modified_gmt":"2026-06-05T02:30:02","slug":"how-to-stabilize-glabridin-in-cosmetic-formulations","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ko\/how-to-stabilize-glabridin-in-cosmetic-formulations\/","title":{"rendered":"\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc548\uc815\ud654\ud558\ub294 \ubc29\ubc95"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14047\" class=\"elementor elementor-14047\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-45fff30 e-flex e-con-boxed e-con e-parent\" data-id=\"45fff30\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-21b23ee elementor-widget elementor-widget-html\" data-id=\"21b23ee\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t  <script type=\"application\/ld+json\">{\n    \"@context\": \"https:\\\/\\\/schema.org\",\n    \"@type\": \"FAQPage\",\n    \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\\\/\\\/glabridinchina.com\\\/how-to-stabilize-glabridin-in-cosmetic-formulations\\\/\"\n    },\n    \"about\": {\n        \"@type\": \"ChemicalSubstance\",\n        \"name\": \"Glabridin\",\n        \"alternateName\": \"\\u5149\\u7518\\u8349\\u5b9a\"\n    },\n    \"publisher\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical\",\n        \"url\": \"https:\\\/\\\/glabridinchina.com\"\n    },\n    \"mainEntity\": [\n        {\n            \"@type\": \"Question\",\n            \"name\": \"How do you stabilize glabridin in cosmetic formulations?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Stabilizing glabridin in cosmetic formulations requires systematic management of the key factors that drive its degradation, including oxidative exposure, trace metal ion contamination, formulation pH, and processing and storage temperature. Practical controls include: (1) antioxidant protection \\u2014 tocopherol at 0.2\\u20130.5% in the oil phase, supplemented by BHT or rosemary extract; (2) metal chelation \\u2014 disodium EDTA at 0.05\\u20130.1%, or sodium phytate for clean-label systems; (3) pH management \\u2014 maintain final formulation pH at 4.0\\u20135.5, verified after all cool-down additions; (4) temperature control \\u2014 incorporate glabridin below 60\\u00b0C, added to the main batch only during cool-down. Packaging selection (airless pump, UV-blocking container) further supports finished product stability.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What is the maximum processing temperature for glabridin?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"The maximum processing temperature is 60\\u00b0C. Stability data (Ao et al., Natural Product Communications, 2010) shows glabridin generally demonstrates good stability below 60\\u00b0C with minimal content change. Above this threshold, thermal degradation accelerates significantly. In practice, glabridin should be pre-dissolved at 40\\u201350\\u00b0C and added to the main batch only during cool-down, never directly into a hot phase.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Does humidity affect glabridin stability?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Yes. Stability data (Ao et al., Natural Product Communications, 2010) shows that at RH 75% and RH 90%, glabridin content is measurably lower than under dry storage conditions, with higher humidity correlating with greater degradation. Both raw materials and finished products are recommended to be stored under light-protected, dry, and sealed conditions.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What pH range stabilizes glabridin?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Glabridin demonstrates good stability under mildly acidic to neutral conditions. Based on formulation experience and stability studies on polyphenolic compounds, a pH range of approximately 4.0\\u20135.5 is generally considered favorable. pH 5.5\\u20136.5 is acceptable with reinforced antioxidant protection. Above pH 7.0, accelerated oxidative degradation occurs under alkaline conditions and glabridin should not be formulated in this range. Always verify final pH after all cool-down additions are complete.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Does encapsulation improve glabridin stability in water-based formulations?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Yes. Huatai's 10% water-soluble grade uses hydroxypropyl \\u03b2-cyclodextrin (HP-\\u03b2-CD) encapsulation with a loading capacity of 15\\u201318%, stably maintained at 10% glabridin content. The HP-\\u03b2-CD shell protects glabridin from aqueous oxidation and improves photostability relative to unencapsulated oil dispersions in aqueous systems. Thermal stability is maintained at approximately 100\\u00b0C processing conditions, and photostability testing shows approximately 10% mass loss over 4 days.\"\n            }\n        }\n    ]\n}<\/script>\n  \n  <style>\n    :root {\n      --color-bg:           #f9f9f7;\n      --color-surface:      #ffffff;\n      --color-border:       #e5e2d9;\n      --color-text:         #1c1c1a;\n      --color-text-muted:   #6a6760;\n      --color-accent:       #2d5a3d;\n      --color-accent-light: #edf4ef;\n      --color-accent-mid:   #4a7c5f;\n      --color-warn:         #7a4f1e;\n      --color-warn-light:   #fdf4eb;\n      --color-data-bg:      #f3f1ed;\n      --font-heading:       'Merriweather', Georgia, 'Times New Roman', serif;\n      --font-body:          'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Helvetica, Arial, sans-serif;\n      --max-width:          800px;\n      --radius:             6px;\n    }\n\n    *, *::before, *::after { box-sizing: border-box; margin: 0; padding: 0; }\n    html { scroll-behavior: smooth; }\n\n    body {\n      font-family: var(--font-body);\n      font-size: 16px;\n      line-height: 1.8;\n      color: var(--color-text);\n      background: var(--color-bg);\n      -webkit-font-smoothing: antialiased;\n    }\n\n    \/* \u2500\u2500 Layout \u2500\u2500 *\/\n    .page-wrap {\n      max-width:100%;\n      margin: 0 auto;\n      padding: 0 24px 80px;\n    }\n\n    \/* \u2500\u2500 Header \u2500\u2500 *\/\n    .site-header {\n      border-bottom: 1px solid var(--color-border);\n      padding: 16px 24px;\n      display: flex;\n      align-items: center;\n      gap: 10px;\n    }\n    .site-header .brand {\n      font-family: var(--font-body);\n      font-size: 14px;\n      font-weight: 600;\n      color: var(--color-accent);\n      text-decoration: none;\n      letter-spacing: 0.01em;\n    }\n    .site-header .sep { color: var(--color-border); }\n    .site-header .section-label {\n      font-size: 13px;\n      color: 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var(--color-border);\n      border-radius: var(--radius);\n      padding: 20px 24px;\n      margin: 20px 0 24px;\n    }\n    .checklist-item {\n      display: flex;\n      align-items: flex-start;\n      gap: 12px;\n      padding: 7px 0;\n      border-bottom: 1px solid var(--color-border);\n      font-size: 15px;\n      line-height: 1.55;\n    }\n    .checklist-item:last-child { border-bottom: none; }\n    .check-box {\n      width: 18px;\n      height: 18px;\n      border: 2px solid var(--color-border);\n      border-radius: 3px;\n      flex-shrink: 0;\n      margin-top: 2px;\n    }\n\n    \/* \u2500\u2500 Related \u2500\u2500 *\/\n    .related-section {\n      margin-top: 52px;\n      padding-top: 28px;\n      border-top: 1px solid var(--color-border);\n    }\n    .related-section h2 {\n      font-family: var(--font-body);\n      font-size: 15px;\n      font-weight: 700;\n      margin-bottom: 14px;\n      color: var(--color-text);\n      border: none;\n      padding: 0;\n      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center;\n      justify-content: space-between;\n      gap: 20px;\n      flex-wrap: wrap;\n    }\n    .cta-box-text { color: rgba(255,255,255,0.85); font-size: 14px; }\n    .cta-box-text strong {\n      color: #fff;\n      display: block;\n      font-size: 16px;\n      margin-bottom: 3px;\n      font-family: var(--font-heading);\n    }\n    .cta-btn {\n      background: #fff;\n      color: var(--color-accent);\n      text-decoration: none;\n      font-weight: 700;\n      font-size: 13px;\n      padding: 9px 20px;\n      border-radius: 4px;\n      white-space: nowrap;\n      letter-spacing: 0.02em;\n      flex-shrink: 0;\n    }\n\n    \/* \u2500\u2500 References \u2500\u2500 *\/\n    .references {\n      margin-top: 44px;\n      padding-top: 24px;\n      border-top: 1px solid var(--color-border);\n    }\n    .references h2 {\n      font-family: var(--font-body);\n      font-size: 12px;\n      font-weight: 700;\n      margin-bottom: 12px;\n      color: var(--color-text-muted);\n      border: none;\n      padding: 0;\n      text-transform: uppercase;\n      letter-spacing: 0.07em;\n    }\n    .references ol { padding-left: 18px; }\n    .references li {\n      font-size: 13px;\n      color: var(--color-text-muted);\n      line-height: 1.6;\n      margin-bottom: 7px;\n    }\n    .references a { color: var(--color-accent); }\n\n    \/* \u2500\u2500 Footer \u2500\u2500 *\/\n    .article-footer {\n      margin-top: 36px;\n      padding-top: 18px;\n      border-top: 1px solid var(--color-border);\n      font-size: 12px;\n      color: var(--color-text-muted);\n      line-height: 1.6;\n    }\n  <\/style>\n<\/head>\n<body>\n  <div class=\"page-wrap\">\n    <header class=\"article-header\">\n      <div class=\"tag-row\">\n        <span class=\"tag\">\uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/span>\n        <span class=\"tag secondary\">\uae00\ub77c\ube0c\ub9ac\ub518<\/span>\n        <span class=\"tag secondary\">\uc81c\ud615 \uc548\uc815\uc131<\/span>\n      <\/div>\n      <p class=\"article-intro\">\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc548\uc815\ud654\ud558\ub824\uba74 \uc0b0\ud654 \ub178\ucd9c, \ubbf8\ub7c9 \uae08\uc18d \uc774\uc628 \uc624\uc5fc, \uc81c\ud615 pH \ubc0f \uac00\uacf5 \uc628\ub3c4\uc640 \uac19\uc774 \ubd84\ud574\ub97c \uc720\ubc1c\ud558\ub294 \uc8fc\uc694 \uc694\uc778\uc744 \uccb4\uacc4\uc801\uc73c\ub85c \uad00\ub9ac\ud574\uc57c \ud569\ub2c8\ub2e4. \uc774 \uae30\uc0ac\uc5d0\uc11c\ub294 \uc6d0\ub8cc \ucde8\uae09\ubd80\ud130 \uc644\uc81c\ud488 \ud3ec\uc7a5\uae4c\uc9c0 \uc644\uc804\ud55c \uc548\uc815\ud654 \ud504\ub85c\ud1a0\ucf5c\uc744 \ub2e4\ub8f9\ub2c8\ub2e4.<\/p>\n      <div class=\"byline\">\n        <span><strong>\ud654\ud0dc \ubc14\uc774\uc624-\ud30c\uc778 \ucf00\ubbf8\uce7c<\/strong> \u2014 2008\ub144\ubd80\ud130 \uace0\uc21c\ub3c4 \ud654\uc7a5\ud488 \ud65c\uc131 \uc131\ubd84\uc744 \uc81c\uc870\ud574 \uc628<\/span>\n        <span style=\"color:var(--color-border)\">\u00b7<\/span>\n        <span>2026\ub144 \ubc1c\ud589<\/span>\n      <\/div>\n    <\/header>\n\n    <article class=\"article-body\">\n\n      <p>\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc548\uc815\ud654\ud558\ub824\uba74 \uc0b0\ud654 \ub178\ucd9c, \ubbf8\ub7c9 \uae08\uc18d \uc774\uc628 \uc624\uc5fc, \uc81c\ud615 pH \ubc0f \uac00\uacf5 \ubc0f \ubcf4\uad00 \uc628\ub3c4\ub97c \ud3ec\ud568\ud558\uc5ec \ubd84\ud574\ub97c \uc720\ubc1c\ud558\ub294 \uc8fc\uc694 \uc694\uc778\uc744 \uccb4\uacc4\uc801\uc73c\ub85c \uad00\ub9ac\ud574\uc57c \ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc694\uc778\ub4e4\uc740 \uc885\uc885 \uc11c\ub85c \uc0c1\ud638 \uc791\uc6a9\ud558\uae30 \ub54c\ubb38\uc5d0 \ud558\ub098\ub9cc \ucd5c\uc801\ud654\ud558\uace0 \ub2e4\ub978 \uc694\uc778\uc744 \ubb34\uc2dc\ud558\uba74 \uc77c\ubc18\uc801\uc73c\ub85c \ub9cc\uc871\uc2a4\ub7ec\uc6b4 \uc7a5\uae30 \uc548\uc815\uc131\uc744 \ub2ec\uc131\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4.<\/p>\n\n      <h2>\ub124 \uac00\uc9c0 \uc548\uc815\ud654 \uc81c\uc5b4<\/h2>\n\n      <!-- Control 1 -->\n      <h3><span class=\"control-badge\">\uc81c\uc5b4 1<\/span> \uc628\ub3c4: \uac00\uacf5 \uc81c\uc57d \uc870\uac74<\/h3>\n\n      <p><strong>\ucd5c\ub300 \uac00\uacf5 \uc628\ub3c4: 60\u00b0C.<\/strong><\/p>\n\n      <p>\uc774 \uc5f4 \uc548\uc815\uc131 \ucc3d\uc740 \uc815\uc758\ub41c \uc870\uac74(Ao et al., <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, 2010, DOI: 10.1177\/1934578X1000501214) \ud558\uc5d0\uc11c \ud655\ub9bd\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 60\u00b0C \ubbf8\ub9cc\uc5d0\uc11c\ub294 \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc77c\ubc18\uc801\uc73c\ub85c \ucd5c\uc18c\ud55c\uc758 \ud568\ub7c9 \ubcc0\ud654\uc640 \ud568\uaed8 \uc6b0\uc218\ud55c \uc548\uc815\uc131\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc774 \uc628\ub3c4 \uc784\uacc4\uac12\uc744 \ucd08\uacfc\ud558\uba74 \uc5f4 \ubd84\ud574\uac00 \ud06c\uac8c \uac00\uc18d\ud654\ub418\uc5b4 \ud65c\uc131 \ud568\ub7c9 \uc190\uc2e4\uc774 \ubc1c\uc0dd\ud569\ub2c8\ub2e4.<\/p>\n\n      <p>\uc81c\ud615 \uc2e4\ubb34\uc5d0\uc11c \uc774\ub294 \ud558\ub098\uc758 \ud611\uc0c1 \ubd88\uac00\ub2a5\ud55c \uaddc\uce59\uc73c\ub85c \ud574\uc11d\ub429\ub2c8\ub2e4. <strong>\uae00\ub77c\ube0c\ub9ac\ub518\uc740 \ub728\uac70\uc6b4 \ub2e8\uacc4\uac00 \uc544\ub2cc \ub0c9\uac01 \uc911\uc5d0\ub9cc \uba54\uc778 \ubc30\uce58\uc5d0 \ucca8\uac00\ud574\uc57c \ud569\ub2c8\ub2e4.<\/strong><\/p>\n\n      <p><strong>\ud45c\uc900 \ud1b5\ud569 \uc21c\uc11c:<\/strong><\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ucc98\ub9ac \ub2e8\uacc4<\/th>\n              <th>\uc628\ub3c4<\/th>\n              <th>\uc791\uc6a9<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uc0ac\uc804 \uc6a9\ud574<\/td>\n              <td>40\u201350\u00b0C<\/td>\n              <td>\uae00\ub77c\ube0c\ub9ac\ub518\uc744 \ud504\ub85c\ud544\ub80c \uae00\ub9ac\ucf5c, \ubd80\ud2f8\ub80c \uae00\ub9ac\ucf5c \ub610\ub294 \uc5d0\ud0c4\uc62c\uc5d0 \uc6a9\ud574\uc2dc\ud0a4\uace0 \ud22c\uba85\ud574\uc9c8 \ub54c\uae4c\uc9c0 \uad50\ubc18\ud569\ub2c8\ub2e4.<\/td>\n            <\/tr>\n            <tr>\n              <td>\uba54\uc778 \ubc30\uce58 \ub0c9\uac01<\/td>\n              <td>50\u00b0C \ubbf8\ub9cc<\/td>\n              <td>\uc0ac\uc804 \uc6a9\ud574\ub41c \ud65c\uc131 \uc131\ubd84\uc744 \ucca8\uac00\ud558\uace0 \ud63c\ud569\ub420 \ub54c\uae4c\uc9c0 \uad50\ubc18\ud569\ub2c8\ub2e4.<\/td>\n            <\/tr>\n            <tr>\n              <td>\ucd5c\ub300 \ub2e8\uae30 \ub178\ucd9c<\/td>\n              <td>60\u00b0C<\/td>\n              <td>\uc9e7\uc740 \uae30\uac04 \ub3d9\uc548 \ud5c8\uc6a9 \uac00\ub2a5\ud569\ub2c8\ub2e4. \uc774 \uc628\ub3c4 \uc774\uc0c1\uc73c\ub85c \uc720\uc9c0\ud558\uc9c0 \ub9c8\uc2ed\uc2dc\uc624.<\/td>\n            <\/tr>\n            <tr>\n              <td>\ubcf4\uad00 (\uc644\uc81c\ud488)<\/td>\n              <td>15\u201325\u00b0C<\/td>\n              <td>\uc5f4, \ube5b, \uc2b5\uae30\ub97c \ud53c\ud558\uc2ed\uc2dc\uc624.<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_thermal_stability.png\"\n             alt=\"6\uac00\uc9c0 \uc628\ub3c4(4\u00b0C, 25\u00b0C, 40\u00b0C, 60\u00b0C, 80\u00b0C, 100\u00b0C)\uc5d0\uc11c 24\uc2dc\uac04 \ub3d9\uc548\uc758 \uae00\ub77c\ube0c\ub9ac\ub518 \ub18d\ub3c4\ub97c \ubcf4\uc5ec\uc8fc\ub294 \uaebe\uc740\uc120 \uadf8\ub798\ud504\">\n        <figcaption>\uadf8\ub9bc 1 \u2014 24\uc2dc\uac04 \ub3d9\uc548 4\u2013100\u00b0C\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uc5f4 \uc548\uc815\uc131. 4\u00b0C, 25\u00b0C, 40\u00b0C \ubc0f 60\u00b0C\uc5d0\uc11c\uc758 \ub18d\ub3c4\ub294 \uc804\ubc18\uc801\uc73c\ub85c \ubcf8\uc9c8\uc801\uc73c\ub85c \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ub429\ub2c8\ub2e4. 80\u00b0C \ubc0f 100\u00b0C\uc5d0\uc11c \ubd84\ud574\uac00 \uc0c1\ub2f9\ud788 \uac00\uc18d\ud654\ub429\ub2c8\ub2e4. \ub370\uc774\ud130: Ao \uc678, <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, 2010.<\/figcaption>\n      <\/figure>\n\n      <div class=\"callout warning\">\n        <p><strong>\uae00\ub77c\ube0c\ub9ac\ub518\uc744 60\u00b0C \uc774\uc0c1\uc5d0\uc11c \ucca8\uac00\ud558\uba74 \uc5b4\ub5bb\uac8c \ub429\ub2c8\uae4c:<\/strong> \uc720\ud654\uac00 \uc644\ub8cc\ub418\uae30 \uc804\uc5d0 \ud65c\uc131 \uc190\uc2e4\uc774 \ubc1c\uc0dd\ud569\ub2c8\ub2e4. \uc644\uc81c\ud488\uc740 T=0\uc5d0\uc11c \uaddc\uaca9 \ub0b4\ub85c \ubd84\uc11d\ub420 \uc218 \uc788\uc9c0\ub9cc(\ubd84\ud574\uac00 \ubd80\ubd84\uc801\uc774\uc5c8\uae30 \ub54c\ubb38\uc5d0), \uac00\uc18d \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\ub294 \uac00\uc18d\ub41c \uc0c9\uc0c1 \ubc1c\ud604\uacfc \ubd84\uc11d\uce58 \ud558\ub77d\uc744 \ubcf4\uc5ec\uc904 \uac83\uc785\ub2c8\ub2e4. \uc65c\ub0d0\ud558\uba74 \uc2dc\uc2a4\ud15c\uc758 \ud56d\uc0b0\ud654 \ub2a5\ub825\uc774 \uc81c\uc870 \uc2dc \uc774\ubbf8 \ubd80\ubd84\uc801\uc73c\ub85c \uc18c\ubaa8\ub418\uc5c8\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <p>\ub3d9\uc77c\ud55c \uc5f0\uad6c\uc5d0\uc11c \uc2b5\ub3c4 \ub610\ud55c \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc911\uc694\ud55c \ud658\uacbd \uc694\uc778\uc73c\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 75% \ubc0f 90% \uc0c1\ub300 \uc2b5\ub3c4(RH)\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518 \ud568\ub7c9\uc740 \uac74\uc870 \ubcf4\uad00 \uc870\uac74\ubcf4\ub2e4 \uc0c1\ub2f9\ud788 \ub0ae\uc558\uc73c\uba70, \uc2b5\ub3c4\uac00 \ub192\uc744\uc218\ub85d \ubd84\ud574\uac00 \ub354 \ub9ce\uc774 \ubc1c\uc0dd\ud558\ub294 \uc0c1\uad00\uad00\uacc4\uac00 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c \ucd5c\uc801\uc758 \uc548\uc815\uc131\uc744 \ub2ec\uc131\ud558\uae30 \uc704\ud574 \uc6d0\ub8cc\uc640 \uc644\uc81c\ud488 \ubaa8\ub450 \ube5b\uc744 \ucc28\ub2e8\ud558\uace0 \uac74\uc870\ud558\uba70 \ubc00\ubd09\ub41c \uc870\uac74\uc5d0\uc11c \ubcf4\uad00\ud558\ub294 \uac83\uc774 \uad8c\uc7a5\ub429\ub2c8\ub2e4.<\/p>\n\n      <!-- Control 2 -->\n      <h3><span class=\"control-badge\">\ub300\uc870\uad70 2<\/span> \ud56d\uc0b0\ud654 \ubcf4\ud638<\/h3>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uc758 \ub450 \uac1c\uc758 \ud398\ub180\uc131 \uc218\uc0b0\uae30(-OH)\ub294 \ud2f0\ub85c\uc2dc\ub098\uc544\uc81c \uc5b5\uc81c \ud65c\uc131\uc758 \uad6c\uc870\uc801 \uc6d0\ucc9c\uc774\uba70 \ub3d9\uc2dc\uc5d0 \uc0b0\ud654 \ucde8\uc57d \ubd80\uc704\uc785\ub2c8\ub2e4. \ud6a8\uacfc\uc801\uc778 \ud56d\uc0b0\ud654 \uc2dc\uc2a4\ud15c\uc740 \uc790\uc720 \ub77c\ub514\uce7c\uc774 \uae00\ub77c\ube0c\ub9ac\ub518 \ubd84\uc790\uc5d0 \ub3c4\ub2ec\ud558\uae30 \uc804\uc5d0 \ud76c\uc0dd\uc801\uc73c\ub85c \uac00\ub85c\ucc55\ub2c8\ub2e4.<\/p>\n\n      <p><strong>\uc81c\ud615 \uc720\ud615\ubcc4 \uad8c\uc7a5 \ud56d\uc0b0\ud654 \uc2dc\uc2a4\ud15c:<\/strong><\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc81c\ud615 \uc720\ud615<\/th>\n              <th>1\ucc28 \ud56d\uc0b0\ud654\uc81c<\/th>\n              <th>2\ucc28 \ud56d\uc0b0\ud654\uc81c<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\ud45c\uc900 O\/W \uc5d0\uba40\uc83c<\/td>\n              <td>\ud1a0\ucf54\ud398\ub864 0.2\u20130.5%<\/td>\n              <td>BHT 0.02\u20130.05%<\/td>\n              <td>\uac00\uc7a5 \uacac\uace0\ud568; \uc720\uc0c1\uc5d0 BHT \ud568\uc720<\/td>\n            <\/tr>\n            <tr>\n              <td>COSMOS \/ \ud074\ub9b0 \ub77c\ubca8<\/td>\n              <td>\ud1a0\ucf54\ud398\ub864 0.2\u20130.5%<\/td>\n              <td>\ub85c\uc988\ub9c8\ub9ac \ucd94\ucd9c\ubb3c 0.05\u20130.2%<\/td>\n              <td>\ubaa8\ub450 COSMOS \uc778\uc99d<\/td>\n            <\/tr>\n            <tr>\n              <td>\ud398\uc774\uc2a4 \uc624\uc77c \/ \ubb34\uc218<\/td>\n              <td>\ud1a0\ucf54\ud398\ub864 0.3\u20130.5%<\/td>\n              <td>\uc544\uc2a4\ucf54\ube4c \ud314\ubbf8\ud14c\uc774\ud2b8 0.05\u20130.1%<\/td>\n              <td>\ub192\uc740 \ud56d\uc0b0\ud654 \ubd80\ud558; \ucd5c\uc18c\ud55c\uc758 \ubb3c<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc218\uc131 \ud1a0\ub108\/\uc5d0\uc13c\uc2a4<\/td>\n              <td>\u2014 (10% HP-\u03b2-CD \ub4f1\uae09 \uc0ac\uc6a9)<\/td>\n              <td>\uc18c\ub4d0 \uc544\uc2a4\ucf54\ube4c \ud3ec\uc2a4\ud398\uc774\ud2b8 0.2\u20130.5%<\/td>\n              <td>HP-\u03b2-CD \ucea1\uc290\ud654\ub294 \uc720\uc0c1 \ubcf4\ud638\ub97c \ucc98\ub9ac\ud569\ub2c8\ub2e4. \uc218\uc0c1 \ud56d\uc0b0\ud654\uc81c\ub294 \uc120\ud0dd\uc801\uc73c\ub85c \uac15\ud654\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout\">\n        <p><strong>\ubc30\uce58 \uc911\uc694:<\/strong> \ud1a0\ucf54\ud398\ub864\uc740 \uc624\uc77c \uc0c1\uc5d0 \ud1b5\ud569\ud558\uac70\ub098 \ud65c\uc131 \uc131\ubd84\uacfc \ud568\uaed8 \uc6a9\ud574\ud574\uc57c \ud558\uba70, \uc218\uc131 \uc0c1\uc5d0 \ucca8\uac00\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \uc9c0\uc9c8 \uc0c1 \ud56d\uc0b0\ud654\uc81c\uc774\uba70 \uc218\uc131 \uc2dc\uc2a4\ud15c\uc5d0 \ubd84\uc0b0\ub420 \ub54c \ubcf4\ud638 \ud6a8\uacfc\uac00 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <p>\ud074\ub9b0 \ub77c\ubca8 COSMOS \uacbd\ub85c\uc758 \uacbd\uc6b0: \ub85c\uc988\ub9c8\ub9ac \ucd94\ucd9c\ubb3c(\uce74\ub974\ub178\uc0b0 \ud568\ub7c9\uc73c\ub85c \ud45c\uc900\ud654)\uc740 \uac00\uc18d \ud14c\uc2a4\ud2b8\uc5d0\uc11c BHT\uc640 \uc720\uc0ac\ud55c \ubcf4\ud638 \uae30\ub2a5\uc744 \uc81c\uacf5\ud558\uba70, COSMOS \uc778\uc99d\uc744 \ubc1b\uace0 Huatai\uc758 COSMOS \uc778\uc99d \uae00\ub77c\ube0c\ub9ac\ub518 \ub4f1\uae09\uacfc \ud638\ud658\ub41c\ub2e4\ub294 \ucd94\uac00 \uc774\uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <!-- Control 3 -->\n      <h3><span class=\"control-badge\">\uc81c\uc5b4 3<\/span> \uae08\uc18d \ud0ac\ub808\uc774\ud2b8\ud654<\/h3>\n\n      <p>\ud56d\uc0b0\ud654\uc81c\ub294 \uc790\uc720 \ub77c\ub514\uce7c \uc5f0\uc1c4 \ubc18\uc751\uc744 \uc885\uacb0\ud568\uc73c\ub85c\uc368 \uae30\ub2a5\ud558\ub294 \ubc18\uba74, \ud0ac\ub808\uc774\ud2b8\uc81c\ub294 Fe \ubc0f Cu\uc640 \uac19\uc740 \uc804\uc774 \uae08\uc18d \uc774\uc628\uc744 \uacb0\ud569\ud558\uc5ec \uc0b0\ud654 \ubc18\uc751\uc744 \ucd09\ub9e4\ud558\ub294 \ub2a5\ub825\uc744 \uc5b5\uc81c\ud568\uc73c\ub85c\uc368 \uc791\uc6a9\ud569\ub2c8\ub2e4. \ub450 \uac00\uc9c0 \uc804\ub7b5\uc740 \uc0c1\ud638 \ubcf4\uc644\uc801\uc774\uba70 \ubd84\ud574 \uacbd\ub85c\uc758 \ub2e4\ub978 \uc9c0\uc810\uc744 \ub2e4\ub8f9\ub2c8\ub2e4.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ud0ac\ub808\uc774\ud2b8\uc81c<\/th>\n              <th>\uc0ac\uc6a9\ub7c9<\/th>\n              <th>\ud638\ud658\uc131<\/th>\n              <th>\ucc38\uace0<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>\ub514\uc18c\ub4d0 EDTA<\/strong><\/td>\n              <td>0.05%\u20130.1%<\/td>\n              <td>\ubc94\uc6a9<\/td>\n              <td>\uac00\uc7a5 \ud6a8\uacfc\uc801; \uc5c5\uacc4 \ud45c\uc900 \uc120\ud0dd<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc18c\ub4d0 \ud30c\uc774\ud14c\uc774\ud2b8<\/td>\n              <td>0.1%\u20130.5%<\/td>\n              <td>COSMOS \ud638\ud658<\/td>\n              <td>\ucc9c\uc5f0 \ud0ac\ub808\uc774\ud2b8\uc81c; \ud56d\uc0b0\ud654 \ubc0f \ud53c\ubd80 \ucee8\ub514\uc154\ub2dd \ud2b9\uc131\ub3c4 \ub098\ud0c0\ub0c4<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc18c\ub4d0 \uae00\ub8e8\ucf54\ub124\uc774\ud2b8<\/td>\n              <td>0.1%\u20130.3%<\/td>\n              <td>\ubc94\uc6a9<\/td>\n              <td>\ub354 \uc21c\ud568; \ucd5c\uc18c \ucca8\uac00\ubb3c \uc81c\ud615\uc6a9<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>\ud6a8\uacfc\uc801\uc778 \ub300\uccb4 \ud0ac\ub808\uc774\ud2b8\uc81c\ub97c \ub3c4\uc785\ud558\uc9c0 \uc54a\uace0 EDTA\ub97c \uc81c\uac70\ud558\uba74 \uc885\uc885 \uc0b0\ud654 \ubcc0\uc0c9 \ubc0f \uc548\uc815\uc131 \ubb38\uc81c\uc758 \uc704\ud5d8\uc774 \uc99d\uac00\ud569\ub2c8\ub2e4. \uc2dd\ubb3c \ucd94\ucd9c\ubb3c, \ube44\ud0c0\ubbfc \uc720\ub3c4\uccb4 \ubc0f \uc2dd\ubb3c\uc131 \uc624\uc77c\uc5d0\ub294 Fe, Cu \ubc0f \uae30\ud0c0 \uae08\uc18d \uc774\uc628\uc758 \uc794\ub958 \ubbf8\ub7c9\uc774 \ud3ec\ud568\ub420 \uc218 \uc788\uc73c\uba70, \uc774\ub294 \ud2b9\uc815 \uc870\uac74\uc5d0\uc11c \uc0b0\ud654 \ubc18\uc751\uc744 \ucd09\ub9e4\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ucd09\ub9e4 \ud6a8\uacfc\ub294 \uc81c\ud615 \uc2dc\uc2a4\ud15c\uc5d0 \ub530\ub77c \uba87 \uc8fc \ub0b4\uc5d0 \ub208\uc5d0 \ubcf4\uc774\ub294 \uc548\uc815\uc131 \ubcc0\ud654\ub85c \ub098\ud0c0\ub0a0 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <p>\uc18c\ub4d0 \ud30c\uc774\ud14c\uc774\ud2b8\ub294 \uad8c\uc7a5\ub418\ub294 COSMOS \uc900\uc218 \ub300\uccb4\ud488\uc785\ub2c8\ub2e4. \uae00\ub77c\ube0c\ub9ac\ub518 \uc81c\ud615\uc5d0 \uc0ac\uc6a9\ub418\ub294 pH \ubc94\uc704(4.0\u20136.5)\uc5d0\uc11c \ud6a8\uacfc\uc801\uc774\uba70, \ud56d\uc0b0\ud654 \ubc0f \ud53c\ubd80 \ucee8\ub514\uc154\ub2dd \ud2b9\uc131\uc744 \ub098\ud0c0\ub0b4\uba70, COSMOS v4\uc5d0\uc11c \uc2b9\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <!-- Control 4 -->\n      <h3><span class=\"control-badge\">\uc81c\uc5b4 4<\/span> pH \uad00\ub9ac<\/h3>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518\uc740 \uc57d\uc0b0\uc131\uc5d0\uc11c \uc911\uc131 \uc870\uac74\uc5d0\uc11c \uc88b\uc740 \uc548\uc815\uc131\uc744 \ub098\ud0c0\ub0b4\uc9c0\ub9cc, \uc54c\uce7c\ub9ac\uc131 \ud658\uacbd\uc5d0\uc11c\ub294 \ubd84\ud574 \uc18d\ub3c4\uac00 \uc99d\uac00\ud569\ub2c8\ub2e4. \uc81c\ud615 \uacbd\ud5d8\uacfc \ud3f4\ub9ac\ud398\ub180 \ud654\ud569\ubb3c\uc5d0 \ub300\ud55c \uc548\uc815\uc131 \uc5f0\uad6c\ub97c \ubc14\ud0d5\uc73c\ub85c, \ud654\uc7a5\ud488 \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc744 \uc720\uc9c0\ud558\uae30 \uc704\ud574 \uc77c\ubc18\uc801\uc73c\ub85c \uc57d 4.0\u20135.5\uc758 pH \ubc94\uc704\uac00 \uc720\ub9ac\ud55c \uac83\uc73c\ub85c \uac04\uc8fc\ub429\ub2c8\ub2e4.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>pH \ubc94\uc704<\/th>\n              <th>\uc548\uc815<\/th>\n              <th>\uad8c\uc7a5 \uc0ac\ud56d<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>4.0\u20135.5<\/strong><\/td>\n              <td><strong>\uc720\ub9ac\ud55c<\/strong><\/td>\n              <td>\ubaa9\ud45c \ubc94\uc704; \uc720\uc9c0\ud558\uae30 \uc704\ud55c \uc644\ucda9<\/td>\n            <\/tr>\n            <tr>\n              <td>5.5\u20136.5<\/td>\n              <td>\uc88b\uc74c<\/td>\n              <td>\ud5c8\uc6a9 \uac00\ub2a5; \ud56d\uc0b0\ud654 \uc2dc\uc2a4\ud15c \uac15\ud654<\/td>\n            <\/tr>\n            <tr>\n              <td>6.5\u20137.0<\/td>\n              <td>\uacbd\uacc4<\/td>\n              <td>\ub354 \ub192\uc740 \ubd84\ud574 \uc704\ud5d8; \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\uc5d0\uc11c \uba74\ubc00\ud788 \ubaa8\ub2c8\ud130\ub9c1<\/td>\n            <\/tr>\n            <tr>\n              <td>&gt;7.0<\/td>\n              <td>\ub098\uc068<\/td>\n              <td>\ud53c\ud558\uc2ed\uc2dc\uc624 \u2014 \uc54c\uce7c\ub9ac\uc131 \uc870\uac74\uc5d0\uc11c\uc758 \uac00\uc18d\ud654\ub41c \uc0b0\ud654 \ubd84\ud574, \uc810\uc9c4\uc801\uc778 \uc0c9\uc0c1 \ubcc0\ud654<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_pH_stability.png\"\n             alt=\"pH 1\u201313\uc5d0 \ub530\ub978 \uae00\ub77c\ube0c\ub9ac\ub518 \ub18d\ub3c4\ub97c \ubcf4\uc5ec\uc8fc\ub294 \uace1\uc120 \ucc28\ud2b8, pH 1\u20136\uc5d0\uc11c \uc548\uc815\uc801\uc778 \ud3c9\ud0c4 \uad6c\uac04, pH 7 \uc774\uc0c1\uc5d0\uc11c \uae09\uaca9\ud55c \uac10\uc18c\">\n        <figcaption>\uadf8\ub9bc 2 \u2014 \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc5d0 \ub300\ud55c pH\uc758 \uc601\ud5a5. pH 1\u20136\uc5d0\uc11c \ub18d\ub3c4\ub294 \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ub418\ub2e4\uac00 pH 7 \uc774\uc0c1\uc5d0\uc11c \uae09\uaca9\ud788 \uac10\uc18c\ud569\ub2c8\ub2e4. pH 13\uc5d0\uc11c\ub294 \ub18d\ub3c4\uac00 \uc57d 7 \u00b5g\/mL\ub85c \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. \ub370\uc774\ud130: Ao \uc678, <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, 2010.<\/figcaption>\n      <\/figure>\n\n      <div class=\"callout warning\">\n        <p><strong>pH \ud655\uc778 \uaddc\uce59:<\/strong> \ucd5c\uc885 pH\ub97c \ud56d\uc0c1 \uce21\uc815\ud558\uc2ed\uc2dc\uc624. <em>~ \ud6c4\uc5d0<\/em> \ubaa8\ub4e0 \ucfe8\ub2e4\uc6b4 \ucca8\uac00\ubb3c\uc740 \uc644\ub8cc\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \ub098\uc774\uc544\uc2e0\uc544\ub9c8\uc774\ub4dc, \ud2b8\ub77c\ub125\uc0bc\uc0b0, \uc77c\ubd80 \ud3a9\ud0c0\uc774\ub4dc\uc640 \uac19\uc740 \ud2b9\uc815 \uacf5\ub3d9 \ud65c\uc131 \uc131\ubd84\uc740 \uc81c\ud615 \uc2dc\uc2a4\ud15c\uc758 \ucd5c\uc885 pH\uc5d0 \uc601\ud5a5\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ud65c\uc131 \uc131\ubd84 \ucca8\uac00 \uc804\uc5d0 \uae30\ubcf8 \uc2dc\uc2a4\ud15c\uc774 \uc57d pH 5.8\ub85c \uce21\uc815\ub418\ub354\ub77c\ub3c4, \ubaa8\ub4e0 \ucfe8\ub2e4\uc6b4 \ub2e8\uacc4 \uc131\ubd84\uc774 \uc644\uc804\ud788 \ud1b5\ud569\ub418\uace0 \uade0\uc9c8\ud654\ub41c \ud6c4 \ucd5c\uc885 pH\uac00 \ub2ec\ub77c\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ucd5c\uc885 \ud3c9\ud615 \uc0c1\ud0dc\uc5d0\uc11c pH\ub97c \ub2e4\uc2dc \uce21\uc815\ud558\uace0 \uc870\uc815\ud558\uc9c0 \uc54a\uc73c\uba74, \uc644\uc131\ub41c \uc81c\ud488\uc758 \uc2e4\uc81c pH\uac00 \uc758\ub3c4\ud55c \ubaa9\ud45c\uce58\uc5d0\uc11c \ubc97\uc5b4\ub098 \uc7a5\uae30 \uc548\uc815\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce60 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <p>\uc720\uae30 \uc644\ucda9 \uc2dc\uc2a4\ud15c, \uc608\ub97c \ub4e4\uc5b4 <strong>\uc2dc\ud2b8\ub974\uc0b0\/\uc2dc\ud2b8\ub974\uc0b0\ub098\ud2b8\ub968<\/strong> (\uc720\ud6a8 \ubc94\uc704 pH 3.0\u20136.2) \ub610\ub294 <strong>\uc816\uc0b0\/\uc816\uc0b0\ub098\ud2b8\ub968<\/strong> (\uc720\ud6a8 \ubc94\uc704 pH 3.6\u20135.8)\uc740 \ud654\uc7a5\ud488 \uc81c\ud615\uc5d0 \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ub450 \uac00\uc9c0 \ubaa8\ub450 \uc6b0\uc218\ud55c \uc81c\ud615 \ud638\ud658\uc131\uc744 \uc81c\uacf5\ud558\uba70, \uc77c\ubc18\uc801\uc73c\ub85c \ubb34\uae30 \uc644\ucda9 \uc2dc\uc2a4\ud15c\uc5d0 \ube44\ud574 \ubbf8\ub7c9 \uae08\uc18d \uc624\uc5fc\uc744 \uc720\ubc1c\ud560 \uc704\ud5d8\uc774 \ub0ae\uc2b5\ub2c8\ub2e4.<\/p>\n\n      <!-- Packaging -->\n      <h2>\ud3ec\uc7a5: \uc548\uc815\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc8fc\uc694 \uc678\ubd80 \uc694\uc778<\/h2>\n\n      <p>\uc81c\ud615 \ud654\ud559 \uc678\uc5d0\ub3c4, \ud3ec\uc7a5\uc740 \ube5b, \uc0b0\uc18c \ubc0f \uae30\ud0c0 \ud658\uacbd \uc2a4\ud2b8\ub808\uc2a4 \uc694\uc778\uc5d0 \ub300\ud55c \ub178\ucd9c\uc744 \uc81c\ud55c\ud568\uc73c\ub85c\uc368 \uc18c\ube44\uc790 \uc0ac\uc6a9 \uc911 \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc744 \uad00\ub9ac\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\ud3ec\uc7a5 \uc120\ud0dd<\/th>\n              <th>\ubcf4\ud638 \uba54\ucee4\ub2c8\uc998<\/th>\n              <th>\uc801\uc6a9 \uac00\ub2a5\ud55c \ud615\uc2dd<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>\uc5d0\uc5b4\ub9ac\uc2a4 \ud38c\ud504<\/strong><\/td>\n              <td>\uac01 \ud38c\ud551 \uc2dc \ubc18\ubcf5\uc801\uc778 \ud5e4\ub4dc\uc2a4\ud398\uc774\uc2a4 O\u2082 \ub178\ucd9c\uc744 \uc81c\uac70\ud569\ub2c8\ub2e4.<\/td>\n              <td>\uc138\ub7fc, \uc5d0\uba40\uc83c, \ub85c\uc158<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ubd88\ud22c\uba85 \ub610\ub294 UV \ucc28\ub2e8 \uc6a9\uae30<\/strong><\/td>\n              <td>\uad11\ubd84\ud574 \uc704\ud5d8 \uac10\uc18c; \ube5b \ub178\ucd9c\uc740 \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uc8fc\uc694 \ubd84\ud574 \uc694\uc778\uc73c\ub85c \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4(Ao \uc678, 2010).<\/td>\n              <td>\ud22c\uba85 \uc624\uc77c \uc138\ub7fc, \ud22c\uba85 \ubcd1\uc5d0 \ub2f4\uae34 \ud1a0\ub108<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ucda9\uc804 \uc911 \uc9c8\uc18c \ube14\ub7ad\ud0b7<\/strong><\/td>\n              <td>\uc81c\uc870 \uc2dc\uc810\uc5d0 \uc6a9\ud574\ub41c O\u2082\ub97c \uc904\uc785\ub2c8\ub2e4.<\/td>\n              <td>\uae34 \uc720\ud1b5\uae30\ud55c\uc744 \uc8fc\uc7a5\ud558\ub294 \ud504\ub9ac\ubbf8\uc5c4 \uc81c\ud615<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>\ubc00\ubd09\ub41c \uc54c\ub8e8\ubbf8\ub284 \ud638\uc77c \ud30c\uc6b0\uce58<\/strong><\/td>\n              <td>\ud6a8\uacfc\uc801\uc778 \ube5b\uacfc \uc0b0\uc18c \ucc28\ub2e8 \uc81c\uacf5<\/td>\n              <td>1\ud68c\uc6a9 \ud3ec\uc7a5, \uc5ec\ud589\uc6a9 \uc0ac\uc774\uc988<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>\uc5d0\uc5b4\ub9ac\uc2a4 \ud38c\ud504 + \ubd88\ud22c\uba85 \uc6a9\uae30\uc758 \uc870\ud569\uc740 \ub300\ubd80\ubd84\uc758 \uc18c\ub9e4 \uc81c\ud615\uc5d0 \uac00\uc7a5 \uc2e4\uc6a9\uc801\uc778 \uc194\ub8e8\uc158\uc785\ub2c8\ub2e4. \uc81c\ud615 \uc790\uccb4\uc5d0 \ubcc0\uacbd\uc774 \ud544\uc694 \uc5c6\uc73c\uba70, \uc644\uc81c\ud488\uc758 \ub450 \uac00\uc9c0 \uc8fc\uc694 \uc5f4\ud654 \uacbd\ub85c\ub97c \uc9c1\uc811\uc801\uc73c\ub85c \ud574\uacb0\ud569\ub2c8\ub2e4.<\/p>\n\n      <!-- Stability Testing -->\n      <h2>\uc548\uc815\uc131 \ud14c\uc2a4\ud2b8 \ud504\ub85c\ud1a0\ucf5c<\/h2>\n\n      <p>\ubc29\uc5b4 \uac00\ub2a5\ud55c \uc720\ud1b5\uae30\ud55c \ub370\uc774\ud130\ub97c \uc0dd\uc131\ud558\uae30 \uc704\ud574 ICH \ud45c\uc900\uc5d0 \ub9de\ucdb0 \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\ub97c \uc870\uc815\ud558\uc2ed\uc2dc\uc624:<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>\uc870\uac74<\/th>\n              <th>\ub9e4\uac1c\ubcc0\uc218<\/th>\n              <th>\uae30\uac04<\/th>\n              <th>\uaddc\uc81c \uadfc\uac70<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>\uac00\uc18d\ud654\ub41c<\/td>\n              <td>40\u00b0C \/ 75% RH<\/td>\n              <td>12\uc8fc<\/td>\n              <td>ICH Q1A(R2)<\/td>\n            <\/tr>\n            <tr>\n              <td>\ub3d9\uacb0-\ud574\ub3d9<\/td>\n              <td>\u221210\u00b0C \u2194 25\u00b0C, 24\uc2dc\uac04 \uc8fc\uae30<\/td>\n              <td>5\ud68c \uc8fc\uae30<\/td>\n              <td>PCPC\/CTFA \uac00\uc774\ub4dc\ub77c\uc778<\/td>\n            <\/tr>\n            <tr>\n              <td>\uad11\uc548\uc815\uc131<\/td>\n              <td>D65 + UV (ICH Q1B \uae30\uc900)<\/td>\n              <td>6\uc8fc<\/td>\n              <td>ICH Q1B<\/td>\n            <\/tr>\n            <tr>\n              <td>\uc2e4\uc2dc\uac04<\/td>\n              <td>25\u00b0C \/ 60% RH<\/td>\n              <td>24\uac1c\uc6d4<\/td>\n              <td>ICH Q1A(R2)<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>\uac01 \uc2dc\uc810\ubcc4 \ud3c9\uac00 \ud56d\ubaa9:<\/strong><\/p>\n      <ul>\n        <li>pH \u2014 0.3 \ub2e8\uc704 \uc774\uc0c1\uc758 \ubcc0\ud654\ub97c \ud45c\uc2dc\ud558\uc2ed\uc2dc\uc624.<\/li>\n        <li>\uc0c9\uc0c1: CIE L*a*b* \u2014 \u0394b* (\ud669\ubcc0 \uc9c0\uc218)\ub97c \uad6c\uccb4\uc801\uc73c\ub85c \ucd94\uc801\ud558\uc2ed\uc2dc\uc624.<\/li>\n        <li>HPLC\uc5d0 \uc758\ud55c \uae00\ub77c\ube0c\ub9ac\ub518 \ubd84\uc11d<\/li>\n        <li>\uc810\ub3c4<\/li>\n        <li>\uad00\ub2a5\uc801: \ub0c4\uc0c8, \uc2dc\uac01\uc801 \uc0c1 \ubd84\ub9ac<\/li>\n      <\/ul>\n\n      <p>40\u00b0C\/75% \uc0c1\ub300 \uc2b5\ub3c4\uc5d0\uc11c \uc57d 12\uc8fc \ub3d9\uc548 \uac00\uc18d \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\ub294 \uc81c\ud615\uc758 \uacac\uace0\uc131\uacfc \uc5f4\ud654 \ucd94\uc138\ub97c \ud3c9\uac00\ud558\uae30 \uc704\ud55c \ucd08\uae30 \uc608\uce21 \ubaa8\ub378\ub85c \ud654\uc7a5\ud488 \uac1c\ubc1c\uc5d0 \uc77c\ubc18\uc801\uc73c\ub85c \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \uc628\ub3c4 \uc758\uc874\uc801 \uc5f4\ud654 \uac70\ub3d9\uc740 \uc544\ub808\ub2c8\uc6b0\uc2a4 \uad00\uacc4\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc124\uba85\ud560 \uc218 \uc788\uc9c0\ub9cc, \uac00\uc18d \ubc0f \uc2e4\uc2dc\uac04 \ubcf4\uad00 \uae30\uac04 \uac04\uc758 \uc9c1\uc811\uc801\uc778 \ub4f1\uac00\uc131\uc740 \ubcf4\ud3b8\uc801\uc73c\ub85c \ud655\ub9bd\ub420 \uc218 \uc5c6\uc73c\uba70 ICH Q1E\uc5d0 \ub530\ub77c \uc81c\ud488\ubcc4 \ub3d9\uc5ed\ud559 \ud3c9\uac00\uac00 \ud544\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n      <p>\uc798 \uc548\uc815\ud654\ub41c \uae00\ub77c\ube0c\ub9ac\ub518 \uc81c\ud615\uc740 \uac00\uc18d \uc548\uc815\uc131 \uc870\uac74\uc5d0\uc11c \ucd5c\uc18c\ud55c\uc758 \ud65c\uc131 \uc131\ubd84 \ubd84\ud574\uc640 \uc81c\ud55c\uc801\uc778 \uc0c9\uc0c1 \ubcc0\ud654\ub97c \ubcf4\uc5ec\uc57c \ud558\uba70, \ud65c\uc131 \uc131\ubd84 \uc190\uc2e4\uc740 \uc77c\ubc18\uc801\uc73c\ub85c 5% \ubbf8\ub9cc\uc744 \ubaa9\ud45c\ub85c \ud558\uace0 \u0394b*\ub294 \uc0ac\uc804 \uc815\uc758\ub41c \uc81c\ud488 \uc0ac\uc591\uc5d0 \ub530\ub77c \ub0ae\uc740 \uc218\uc900\uc73c\ub85c \uc720\uc9c0\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n      <!-- Checklist -->\n      <h2>\uc548\uc815\ud654 \uccb4\ud06c\ub9ac\uc2a4\ud2b8<\/h2>\n\n      <p>\uae00\ub77c\ube0c\ub9ac\ub518 \ud568\uc720 \uc81c\ud615\uc744 \uc548\uc815\uc131 \ud14c\uc2a4\ud2b8\uc5d0 \ucd9c\uc2dc\ud558\uae30 \uc804\uc5d0 \ub2e4\uc74c \uac01 \ud56d\ubaa9\uc744 \ud655\uc778\ud558\uc2ed\uc2dc\uc624:<\/p>\n\n      <div class=\"checklist\">\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>60\u00b0C \uc774\ud558\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518 \ucca8\uac00 \u2014 \ub0c9\uac01 \uc2dc \ucca8\uac00, SOP\uc5d0 \ubb38\uc11c\ud654\ub428<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\ud56d\uc0b0\ud654\uc81c(\ud1a0\ucf54\ud398\ub864) \uc624\uc77c \uc0c1\uc5d0 \u22650.2%\ub85c \ud568\uc720<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\uae08\uc18d \ud0ac\ub808\uc774\ud2b8\uc81c(EDTA \ub610\ub294 \uc18c\ub4d0 \ud53c\ud14c\uc774\ud2b8) \uc218\uc6a9\uc561 \uc0c1\uc5d0 \uc874\uc7ac<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\ubaa8\ub4e0 \ub0c9\uac01 \ucca8\uac00 \ud6c4 \ucd5c\uc885 pH \uce21\uc815: \ubaa9\ud45c 4.0\u20135.5<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\uc720\ud1b5 \uae30\ud55c \ub3d9\uc548 pH \uc720\uc9c0\ub97c \uc704\ud55c \uc218\uc6a9\uc561 \uc0c1\uc758 \uc644\ucda9 \uc2dc\uc2a4\ud15c<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\ud3ec\uc7a5: \uc5d0\uc5b4\ub9ac\uc2a4 \ud38c\ud504 \ubc0f\/\ub610\ub294 UV \ucc28\ub2e8 \uc6a9\uae30 \ud655\uc778\ub428<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>ICH Q1A(R2) \ubc0f Q1B\uc5d0 \ub530\ub978 \uc548\uc815\uc131 \ud504\ub85c\uadf8\ub7a8<\/span>\n        <\/div>\n        <div class=\"checklist-item\">\n          <div class=\"check-box\"><\/div>\n          <span>\ubaa8\ub4e0 \uc2dc\uc810\uc5d0\uc11c \u0394b* \ucd94\uc801 (\ud669\ubcc0 \uc9c0\uc218)<\/span>\n        <\/div>\n      <\/div>\n\n      <div class=\"callout\">\n        <p>\ubaa8\ub4e0 \ubc30\uce58\uc5d0\ub294 COA, TDS \ubc0f SDS\/MSDS\uac00 \ud568\uaed8 \uc81c\uacf5\ub429\ub2c8\ub2e4. \ucd94\uac00 \ud14c\uc2a4\ud2b8\ub294 \uc694\uccad \uc2dc \uac00\ub2a5\ud569\ub2c8\ub2e4.<\/p>\n      <\/div>\n\n      <!-- Related -->\n      <div class=\"related-section\">\n        <h2>\uad00\ub828 \uc790\ub8cc<\/h2>\n        <div class=\"related-links\">\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/glabridin\/\">\n            <span>\ud654\uc7a5\ud488 \uc81c\ud615\uc744 \uc704\ud55c \uae00\ub77c\ube0c\ub9ac\ub518 \uac00\uc774\ub4dc \u2014 \uc644\uc804 \uae30\uc220 \ucc38\uc870<br><small style=\"color:var(--color-text-muted);font-weight:400\">\uc804\uccb4 \uc548\uc815\uc131 \ub370\uc774\ud130, \ub4f1\uae09 \ub9e4\ud2b8\ub9ad\uc2a4 \ubc0f \uc81c\ud615 \ud504\ub85c\ud1a0\ucf5c<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/ko\/why-does-glabridin-discolor-in-emulsions-huatai-bio-fine-chemical\/\">\n            <span>\uc5d0\uba40\uc83c\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \ubcc0\uc0c9\ub418\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00\uc694?<br><small style=\"color:var(--color-text-muted);font-weight:400\">\uc81c\ud615 \ubcc0\uc0c9\uc5d0 \ub300\ud55c \uadfc\ubcf8 \uc6d0\uc778 \ubd84\uc11d \ubc0f \uc9c4\ub2e8 \ud504\ub808\uc784\uc6cc\ud06c<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"\/ko\/\">\n            <span>\ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc694\uad6c\ud558\ub294 pH \ubc94\uc704\ub294 \uc5bc\ub9c8\uc778\uac00\uc694?<br><small style=\"color:var(--color-text-muted);font-weight:400\">\uc644\ucda9\uc561 \uc120\ud0dd \ubc0f pH \uad00\ub9ac \uc0c1\uc138 \uc124\uba85<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"\/ko\/\">\n            <span>\uae00\ub77c\ube0c\ub9ac\ub518\uc774 \uc218\uc131 \uc2dc\uc2a4\ud15c\uc5d0\uc11c \uc791\uc6a9\ud560 \uc218 \uc788\ub098\uc694?<br><small style=\"color:var(--color-text-muted);font-weight:400\">HP-\u03b2-CD \ub4f1\uae09 \uae30\uc220 \uc0ac\uc591 \ubc0f \uc218\uc6a9\uc561 \ud1b5\ud569<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n        <\/div>\n      <\/div>\n\n      <!-- CTA -->\n      <div class=\"cta-box\">\n        <div class=\"cta-box-text\">\n          <strong>\uc0d8\ud50c, COA \ub610\ub294 \uae30\uc220 \uc0c1\ub2f4 \uc694\uccad<\/strong>\n          glabridinchina.com \u00b7 jelly@huataibio.com \u00b7 +86 17868678161\n        <\/div>\n        <a class=\"cta-btn\" href=\"https:\/\/glabridinchina.com\/ko\/product-tag\/\">\ubb38\uc758\ud558\uae30 \u2192<\/a>\n      <\/div>\n\n      <!-- References -->\n      <div class=\"references\">\n        <h2>\ucc38\uace0 \uc790\ub8cc<\/h2>\n        <ol>\n          <li>Ao M, Shi Y, Cui Y, Guo W, Wang J, Yu L. \uae00\ub77c\ube0c\ub9ac\ub518 \uc548\uc815\uc131\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc694\uc778. <em>\ucc9c\uc5f0\ubb3c \ucee4\ubba4\ub2c8\ucf00\uc774\uc158<\/em>, Vol. 5(12), 1907\u20131912, 2010. DOI: 10.1177\/1934578X1000501214. PMID: 21299118.<\/li>\n          <li>Yokota T, Nishio H, Kubota Y, Mizoguchi M. \uac10\ucd08 \ucd94\ucd9c\ubb3c\uc5d0\uc11c \ucd94\ucd9c\ud55c \uae00\ub77c\ube0c\ub9ac\ub518\uc758 \uba5c\ub77c\ub2cc \uc0dd\uc131 \ubc0f \uc5fc\uc99d \uc5b5\uc81c \ud6a8\uacfc. <em>Pigment Cell Research<\/em>, 11(6), 355\u2013361, 1998. DOI: 10.1111\/j.1600-0749.1998.tb00494.x.<\/li>\n          <li>ICH Q1A(R2): \uc2e0\uaddc \uc758\uc57d\ud488 \uc6d0\ub8cc \ubc0f \uc644\uc81c\ud488\uc758 \uc548\uc815\uc131 \uc2dc\ud5d8. \uad6d\uc81c\uc758\uc57d\ud488\uaddc\uc81c\uc870\ud654\uc704\uc6d0\ud68c, 2003.<\/li>\n          <li>ICH Q1B: \uc2e0\uaddc \uc6d0\ub8cc\uc758\uc57d\ud488 \ubc0f \uc644\uc81c\uc758\uc57d\ud488\uc758 \uad11\uc548\uc815\uc131 \uc2dc\ud5d8. \uad6d\uc81c\uc758\uc57d\ud488\uaddc\uc81c\uc870\ud654\uc704\uc6d0\ud68c, 1996.<\/li>\n          <li>ICH Q1E: \uc548\uc815\uc131 \ub370\uc774\ud130 \ud3c9\uac00. \uad6d\uc81c\uc758\uc57d\ud488\uaddc\uc81c\uc870\ud654\uc704\uc6d0\ud68c, 2003.<\/li>\n        <\/ol>\n      <\/div>\n\n      <div class=\"article-footer\">\n        <p>\uc804\ubb38 \ud654\uc7a5\ud488 \uc81c\ud615 \uac1c\ubc1c\uc790 \ubc0f \uc5f0\uad6c\uac1c\ubc1c \ub2f4\ub2f9\uc790\ub97c \uc704\ud55c \uc790\ub8cc\uc785\ub2c8\ub2e4. \uaddc\uc81c \uad00\ub828 \uc870\uc5b8\uc744 \uad6c\uc131\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<br>\n        \ubc1c\ud589 2026\ub144 \u2014 Huatai Bio-Fine Chemical, Xi'an, Shaanxi, China.<\/p>\n      <\/div>\n\n    <\/article>\n  <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>FAQ \uae00\ub77c\ube0c\ub9ac\ub518 \uc81c\ud615 \uc548\uc815\uc131 \ud654\uc7a5\ud488 \uc81c\ud615\uc5d0\uc11c \uae00\ub77c\ube0c\ub9ac\ub518\uc744 \uc548\uc815\ud654\ud558\ub824\uba74 \ubd84\ud574\ub97c \uc720\ubc1c\ud558\ub294 \uc8fc\uc694 \uc694\uc778\uc778 \uc0b0\ud654 \ub178\ucd9c, \ubbf8\ub7c9 \uae08\uc18d\u2026\uc744 \uccb4\uacc4\uc801\uc73c\ub85c \uad00\ub9ac\ud574\uc57c \ud569\ub2c8\ub2e4.<\/p>","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[414],"tags":[],"class_list":["post-14047","post","type-post","status-publish","format-standard","hentry","category-troubleshooting-faq"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How to Stabilize Glabridin in Cosmetic Formulations | Huatai Bio-Fine Chemical<\/title>\n<meta name=\"description\" content=\"A complete stabilization protocol for glabridin in cosmetic formulations: temperature control, antioxidant system design, metal chelation, pH management, and packaging. 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