{"id":6821,"date":"2025-11-21T07:00:26","date_gmt":"2025-11-21T07:00:26","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=6821"},"modified":"2025-11-21T07:00:27","modified_gmt":"2025-11-21T07:00:27","slug":"tranexamic-acid-skincare-breakthrough-for-melasma-treatment","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ja\/tranexamic-acid-skincare-breakthrough-for-melasma-treatment\/","title":{"rendered":"\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u30b9\u30ad\u30f3\u30b1\u30a2\uff1a\u809d\u6591\u6cbb\u7642\u306b\u304a\u3051\u308b\u753b\u671f\u7684\u306a\u9032\u6b69"},"content":{"rendered":"<p><a href=\"https:\/\/glabridinchina.com\/ja\/product\/tranexamic-acid\/\"><mark class=\"has-inline-color has-vivid-cyan-blue-color\">\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178<\/mark><\/a>\u3001\u30a2\u30df\u30ce\u9178\u30ea\u30b8\u30f3\uff08lysine\uff09\u306e\u5408\u6210\u8a98\u5c0e\u4f53\u3067\u3042\u308a\u3001\u76ae\u819a\u79d1\u5b66\u5206\u91ce\u306b\u304a\u3044\u3066A\u30ea\u30b9\u30c8\u306e\u6709\u52b9\u30b9\u30ad\u30f3\u30b1\u30a2\u6210\u5206\u3068\u3057\u3066\u6025\u901f\u306b\u666e\u53ca\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7406\u7531\u306f\u3001\u8272\u7d20\u6c88\u7740\u6cbb\u7642\u306b\u304a\u3051\u308b\u5353\u8d8a\u3057\u305f\u52b9\u679c\u306b\u3042\u308a\u307e\u3059\u3002\u5f53\u521d\u306f\u6b62\u8840\u5264\u3068\u3057\u3066\u5168\u8eab\u6295\u4e0e\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u5916\u7528\u5857\u5e03\u306b\u3088\u308a\u5f37\u529b\u306a\u6297\u30d7\u30e9\u30b9\u30df\u30f3\u4f5c\u7528\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u3001\u8272\u7d20\u6c88\u7740\u7d4c\u8def\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u809d\u6591\u3084\u708e\u75c7\u5f8c\u8272\u7d20\u6c88\u7740\u3068\u3044\u3063\u305f\u96e3\u6cbb\u6027\u306e\u75c7\u72b6\u306b\u975e\u5e38\u306b\u52b9\u679c\u7684\u3067\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u9ad8\u7d14\u5ea6\u30d1\u30a6\u30c0\u30fc\u3092\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u5264\u306b\u4f7f\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u5b89\u5b9a\u6027\u304c\u78ba\u4fdd\u3055\u308c\u3001\u30b7\u30df\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u5316\u3068\u5168\u4f53\u7684\u306a\u8272\u7d20\u6c88\u7740\u8efd\u6e1b\u306e\u81e8\u5e8a\u52b9\u679c\u304c\u6700\u5927\u5316\u3055\u308c\u307e\u3059\u3002<\/p><h2 class=\"wp-block-heading\" id=\"h-i-tranexamic-acid-mechanism-for-pigment-reduction\">I. \u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306b\u3088\u308b\u8272\u7d20\u6c88\u7740\u8efd\u6e1b\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/h2><p>\u30b9\u30ad\u30f3\u30b1\u30a2\u306b\u304a\u3051\u308b\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\uff08TXA\u3068\u7565\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\uff09\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u3001\u5f93\u6765\u306e\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u5264\u3068\u306f\u7570\u306a\u308a\u3001\u8272\u7d20\u6c88\u7740\u306b\u5bfe\u3057\u3066\u591a\u89d2\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p><div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><a href=\"https:\/\/glabridinchina.com\/ja\/product\/tranexamic-acid\/\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"576\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-1024x576.jpg\" alt=\"\" class=\"wp-image-6039\" style=\"width:533px;height:auto\" srcset=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-1024x576.jpg 1024w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-300x169.jpg 300w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-768x432.jpg 768w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-18x10.jpg 18w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-600x338.jpg 600w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-1x1.jpg 1w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract-10x6.jpg 10w, https:\/\/glabridinchina.com\/wp-content\/uploads\/2025\/10\/Tranexamic-Acid-extract.jpg 1242w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure><\/div><h3 class=\"wp-block-heading\" id=\"h-blocking-the-inflammatory-cascade\">\u708e\u75c7\u30ab\u30b9\u30b1\u30fc\u30c9\u306e\u30d6\u30ed\u30c3\u30af<\/h3><ul class=\"wp-block-list\"><li>\u6297\u30d7\u30e9\u30b9\u30df\u30f3\u6d3b\u6027\uff1a\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306f\u3001\u30d7\u30e9\u30b9\u30df\u30ce\u30fc\u30b2\u30f3\u304b\u3089\u30d7\u30e9\u30b9\u30df\u30f3\u3078\u306e\u5909\u63db\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u4f5c\u7528\u3057\u307e\u3059\u3002\u30d7\u30e9\u30b9\u30df\u30f3\u6d3b\u6027\u306f\u3001\u7279\u306b\u7d2b\u5916\u7dda\u66dd\u9732\u3084\u708e\u75c7\u30a4\u30d9\u30f3\u30c8\u5f8c\u306b\u3001\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\u3092\u523a\u6fc0\u3059\u308b\u708e\u75c7\u6027\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u3084\u6210\u9577\u56e0\u5b50\u306e\u653e\u51fa\u3092\u5897\u52a0\u3055\u305b\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n<li>\u809d\u6591\u6cbb\u7642\uff1a\u76ae\u819a\u7d30\u80de\uff08\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\uff09\u3068\u8272\u7d20\u5f62\u6210\u7d30\u80de\uff08\u30e1\u30e9\u30ce\u30b5\u30a4\u30c8\uff09\u9593\u306e\u3053\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u9632\u3050\u3053\u3068\u306b\u3088\u308a\u3001\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306f\u30e1\u30e9\u30cb\u30f3\u751f\u6210\u3068\u8ee2\u9001\u3092\u52b9\u679c\u7684\u306b\u6291\u5236\u3057\u307e\u3059\u3002\u3053\u306e\u6a19\u7684\u5316\u3055\u308c\u305f\u4f5c\u7528\u306b\u3088\u308a\u3001\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3068\u540c\u7b49\u306e\u6709\u52b9\u6027\u304c\u3042\u308a\u306a\u304c\u3089\u3001\u526f\u4f5c\u7528\u304c\u5c11\u306a\u304f\u3001\u512a\u308c\u305f\u809d\u6591\u6cbb\u7642\u306e\u9078\u629e\u80a2\u3068\u306a\u308a\u307e\u3059\u3002<\/li><\/ul><h3 class=\"wp-block-heading\" id=\"h-anti-inflammatory-and-redness-reduction\">\u6297\u708e\u75c7\u4f5c\u7528\u3068\u8d64\u307f\u8efd\u6e1b<\/h3><ul class=\"wp-block-list\"><li>\u76ae\u819a\u93ae\u9759\uff1a\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306e\u6839\u5e95\u306b\u3042\u308b\u6297\u708e\u75c7\u4f5c\u7528\u306f\u3001\u808c\u3092\u843d\u3061\u7740\u304b\u305b\u3001\u8272\u7d20\u6c88\u7740\u306e\u8840\u7ba1\u6027\u8981\u7d20\u3092\u8efd\u6e1b\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u8d64\u307f\u306e\u76ee\u7acb\u3064\u8efd\u6e1b\u306b\u3064\u306a\u304c\u308a\u3001\u654f\u611f\u808c\u7528\u7f8e\u5bb9\u6db2\u3078\u306e\u914d\u5408\u306b\u7406\u60f3\u7684\u3067\u3059\u3002<\/li><\/ul><h2 class=\"wp-block-heading\" id=\"h-ii-commercial-success-naturium-tranexamic-topical-acid-5-serum\">II. \u5546\u696d\u7684\u6210\u529f\uff1aNaturium \u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u5916\u7528\u6db2 5% \u30bb\u30e9\u30e0<\/h2><p>Naturium \u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u5916\u7528\u6db2 5% \u30bb\u30e9\u30e0\u306f\u3001\u5f37\u529b\u306a\u6fc3\u5ea6\u3068\u30a4\u30f3\u30c6\u30ea\u30b8\u30a7\u30f3\u30c8\u306a\u6210\u5206\u76f8\u4e57\u52b9\u679c\u3092\u6d3b\u7528\u3057\u3001\u52b9\u679c\u7684\u306a\u8272\u7d20\u6c88\u7740\u6cbb\u7642\u306b\u304a\u3051\u308b\u5546\u696d\u7684\u57fa\u6e96\u3092\u4f53\u73fe\u3057\u3066\u3044\u307e\u3059\u3002<\/p><h3 class=\"wp-block-heading\" id=\"h-optimal-concentration-and-synergy\">\u6700\u9069\u306a\u6fc3\u5ea6\u3068\u76f8\u4e57\u52b9\u679c<\/h3><ul class=\"wp-block-list\"><li>\u9ad8\u6fc3\u5ea6\uff1aNaturium\u306e\u30bb\u30e9\u30e0\u306f\u30015\u30d1\u30fc\u30bb\u30f3\u30c8\u3068\u3044\u3046\u9ad8\u6fc3\u5ea6\u3067\u81e8\u5e8a\u7684\u306b\u95a2\u9023\u6027\u306e\u9ad8\u3044\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u3092\u914d\u5408\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6fc3\u5ea6\u4ee5\u4e0a\u3092\u4f7f\u7528\u3057\u305f\u5c40\u6240\u88fd\u5264\u306f\u3001\u7279\u306b\u8868\u76ae\u6027\u809d\u6591\u306b\u5bfe\u3057\u3066\u6709\u671b\u306a\u7d50\u679c\u3092\u793a\u3059\u3053\u3068\u304c\u7814\u7a76\u3067\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n\n<li>\u30de\u30eb\u30c1\u30a2\u30af\u30b7\u30e7\u30f3\u30b7\u30ca\u30b8\u30fc\uff1a\u52b9\u679c\u3092\u9ad8\u3081\u308b\u305f\u3081\u306b\u3001\u3053\u306e\u51e6\u65b9\u306b\u306f\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3084\u30b3\u30a6\u30b8\u9178\u306a\u3069\u306e\u4ed6\u306e\u5f37\u529b\u306a\u7f8e\u767d\u6210\u5206\u304c\u542b\u307e\u308c\u3066\u3044\u307e\u3059\u3002 <a class=\"wpil_keyword_link\" href=\"https:\/\/glabridinchina.com\/ja\/licorice-family\/\" target=\"_blank\" rel=\"noopener\" title=\"\u7518\u8349\u6839\u30a8\u30ad\u30b9\" data-wpil-keyword-link=\"linked\" data-wpil-monitor-id=\"4510\">\u7518\u8349\u6839\u30a8\u30ad\u30b9<\/a>\u3002\u3053\u306e\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3068\u306e\u76f8\u4e57\u52b9\u679c\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306f\u708e\u75c7\u6027\u30c8\u30ea\u30ac\u30fc\u306b\u5bfe\u51e6\u3057\u3001 <a href=\"https:\/\/glabridinchina.com\/ja\/product\/niacinamide\/\"><mark class=\"has-inline-color has-vivid-cyan-blue-color\">\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9<\/mark><\/a> \u306f\u76ae\u819a\u30d0\u30ea\u30a2\u3092\u5f37\u5316\u3057\u3001\u8272\u7d20\u8ee2\u9001\u3092\u30d6\u30ed\u30c3\u30af\u3057\u3001\u30b3\u30a6\u30b8\u9178\u306f\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u5305\u62ec\u7684\u306a\u30b7\u30df\u306e\u6539\u5584\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002<\/li><\/ul><h3 class=\"wp-block-heading\" id=\"h-application-and-efficacy\">\u9069\u7528\u3068\u6709\u52b9\u6027<\/h3><ul class=\"wp-block-list\"><li>\u81e8\u5e8a\u7684\u6709\u52b9\u6027\uff1aNaturium\u306e\u30bb\u30e9\u30e0\u306e\u3088\u3046\u306a\u88fd\u54c1\u306f\u3001\u7d99\u7d9a\u7684\u306a\u4f7f\u7528\u304b\u30898\u9031\u9593\u4ee5\u5185\u306b\u30b7\u30df\u3068\u5168\u4f53\u7684\u306a\u808c\u306e\u660e\u308b\u3055\u306e\u9855\u8457\u306a\u6539\u5584\u3092\u793a\u3059\u81e8\u5e8a\u7684\u6709\u52b9\u6027\u30c7\u30fc\u30bf\u306b\u3088\u3063\u3066\u88cf\u4ed8\u3051\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u3088\u304f\u3042\u308a\u307e\u3059\u3002<\/li><\/ul><h2 class=\"wp-block-heading\" id=\"h-iii-commercial-sourcing-of-cosmetic-raw-material\">III\uff0e\u5316\u7ca7\u54c1\u539f\u6599\u306e\u5546\u696d\u7684\u8abf\u9054<\/h2><p>\u72ec\u81ea\u306e\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u30b9\u30ad\u30f3\u30b1\u30a2\u88fd\u54c1\u3092\u51e6\u65b9\u3059\u308b\u30d6\u30e9\u30f3\u30c9\u306b\u3068\u3063\u3066\u3001\u539f\u6750\u6599\u306e\u8abf\u9054\u306b\u306f\u7d14\u5ea6\u3068\u5546\u696d\u7684\u5b9f\u73fe\u53ef\u80fd\u6027\u3078\u306e\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002<\/p><h3 class=\"wp-block-heading\" id=\"h-high-purity-powder-procurement\">\u9ad8\u7d14\u5ea6\u7c89\u672b\u306e\u8abf\u9054<\/h3><ul class=\"wp-block-list\"><li>\u5316\u7ca7\u54c1\u539f\u6599\uff1a\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306f\u3001\u305d\u306e\u5b89\u5b9a\u6027\u3068\u6c34\u6027\u307e\u305f\u306f\u30bb\u30e9\u30e0\u30d9\u30fc\u30b9\u306e\u51e6\u65b9\u3078\u306e\u5bb9\u6613\u306a\u914d\u5408\u6027\u304b\u3089\u3001\u4e3b\u306b\u9ad8\u7d14\u5ea6\u7c89\u672b\u3068\u3057\u3066\u8abf\u9054\u3055\u308c\u307e\u3059\u3002\u88fd\u9020\u696d\u8005\u306f\u3001\u9ad8\u7d14\u5ea6\u7c89\u672b\u304c\u3001\u4e00\u8cab\u3057\u305f\u518d\u73fe\u6027\u306e\u3042\u308b\u81e8\u5e8a\u7684\u6709\u52b9\u6027\u306e\u305f\u3081\u306b\u53b3\u683c\u306a\u696d\u754c\u57fa\u6e96\u3092\u6e80\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n\n<li>\u30d0\u30eb\u30af\u4fa1\u683c\uff1a\u7279\u6b8a\u3067\u9700\u8981\u306e\u9ad8\u3044\u6709\u52b9\u306a\u30b9\u30ad\u30f3\u30b1\u30a2\u6210\u5206\u3068\u3057\u3066\u3001\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u7c89\u672b\u306e\u6709\u5229\u306a\u30d0\u30eb\u30af\u4fa1\u683c\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u306f\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002\u5c02\u9580\u306e\u88fd\u9020\u696d\u8005\u304b\u3089\u306e\u76f4\u63a5\u8abf\u9054\u306f\u3001\u54c1\u8cea\u7ba1\u7406\u3068\u6700\u9069\u306a\u30d0\u30eb\u30af\u4fa1\u683c\u306e\u4e21\u65b9\u306e\u5229\u70b9\u3092\u4fdd\u8a3c\u3057\u307e\u3059\u3002<\/li><\/ul><h2 class=\"wp-block-heading\" id=\"h-iv-conclusion\">IV\uff0e\u7d50\u8ad6<\/h2><p>\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306f\u3001\u8272\u7d20\u6c88\u7740\u306e\u8efd\u6e1b\u3068\u52b9\u679c\u7684\u306a\u809d\u6591\u6cbb\u7642\u3078\u306e\u691c\u8a3c\u6e08\u307f\u3067\u4f4e\u523a\u6fc0\u6027\u306e\u7d4c\u8def\u3092\u63d0\u4f9b\u3059\u308b\u5f37\u529b\u306a\u6709\u52b9\u306a\u30b9\u30ad\u30f3\u30b1\u30a2\u6210\u5206\u3067\u3059\u3002Naturium Tranexamic Topical Acid 5% Serum\u306e\u3088\u3046\u306a\u9ad8\u6fc3\u5ea6\u30bb\u30e9\u30e0\u306b\u4ee3\u8868\u3055\u308c\u308b\u305d\u306e\u6210\u529f\u306f\u3001\u9ad8\u3044\u81e8\u5e8a\u7684\u6709\u52b9\u6027\u3092\u63d0\u4f9b\u3059\u308b\u591a\u6a5f\u80fd\u88fd\u54c1\u306b\u5bfe\u3059\u308b\u5e02\u5834\u306e\u9700\u8981\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u9ad8\u7d14\u5ea6\u7c89\u672b\u306e\u6226\u7565\u7684\u306a\u8abf\u9054\u306f\u3001\u9ad8\u5ea6\u306a\u8272\u7d20\u6c88\u7740\u6cbb\u7642\u30bd\u30ea\u30e5\u30fc\u30b7\u30e7\u30f3\u306b\u5bfe\u3059\u308b\u9ad8\u307e\u308b\u6d88\u8cbb\u8005\u306e\u30cb\u30fc\u30ba\u3092\u6e80\u305f\u305d\u3046\u3068\u3059\u308b\u88fd\u9020\u696d\u8005\u306b\u3068\u3063\u3066\u91cd\u8981\u3067\u3059\u3002<\/p><hr class=\"wp-block-separator has-alpha-channel-opacity\" 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\u6280\u8853\u8cc7\u6599\u3092\u5165\u624b\uff1a\u6280\u8853\u30c7\u30fc\u30bf\u30b7\u30fc\u30c8\u3001\u5b89\u5168\u30c7\u30fc\u30bf\u30b7\u30fc\u30c8\u3001\u5206\u6790\u8a3c\u660e\u66f8\u3001\u81e8\u5e8a\u6709\u52b9\u6027\u30ec\u30dd\u30fc\u30c8\u306b\u30a2\u30af\u30bb\u30b9\u3067\u304d\u307e\u3059\u3002 <\/p><p>\ud83d\udd2c \u7121\u6599\u30b5\u30f3\u30d7\u30eb\u3092\u304a\u7533\u3057\u8fbc\u307f\u304f\u3060\u3055\u3044\uff1a\u30c8\u30e9\u30cd\u30ad\u30b5\u30e0\u9178\u306e\u5b89\u5b9a\u3057\u305f\u9ad8\u52b9\u679c\u514d\u75ab\u529b\u5411\u4e0a\u52b9\u679c\u3092\u4eca\u3059\u3050\u304a\u8a66\u3057\u304f\u3060\u3055\u3044\u3002 <\/p><p>\ud83d\udcde 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