{"id":12284,"date":"2026-06-01T06:45:48","date_gmt":"2026-06-01T06:45:48","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=12284"},"modified":"2026-07-01T03:30:46","modified_gmt":"2026-07-01T03:30:46","slug":"advanced-formulation-strategies-for-kojic-acid-arbutin-systems","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ja\/advanced-formulation-strategies-for-kojic-acid-arbutin-systems\/","title":{"rendered":"\u30b3\u30a6\u30b8\u9178\u30a2\u30eb\u30d6\u30c1\u30f3\u7cfb\u88fd\u5264\u306e\u9ad8\u5ea6\u306a\u88fd\u5264\u5316\u6226\u7565"},"content":{"rendered":"

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\u30a2\u30c3\u30bb\u30a4\u7d14\u5ea6\uff08HPLC\uff09<\/td>\u2265 99.0%<\/td>\u2265 99.5%<\/td><\/tr>
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\u878d\u70b9\u7bc4\u56f2<\/td>152\u2103\uff5e156\u2103<\/td>202\u2103\uff5e206\u2103<\/td><\/tr>
\u91cd\u91d1\u5c5e\u5408\u8a08<\/td>10 ppm\u672a\u6e80<\/td>10 ppm\u672a\u6e80<\/td><\/tr>
\u30d2\u30c9\u30ed\u30ad\u30ce\u30f3\u4e0d\u7d14\u7269<\/td>\u8a72\u5f53\u306a\u3057<\/td>5 ppm\u672a\u6e80<\/td><\/tr>
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\u30ad\u30b5\u30f3\u30bf\u30f3\u30ac\u30e0\u307e\u305f\u306f\u30dd\u30ea\u30a2\u30af\u30ea\u30ec\u30fc\u30c8\u30af\u30ed\u30b9\u30dd\u30ea\u30de\u30fc-6\u3067\u51e6\u65b9\u3092\u5897\u7c98\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u9ad8pH\u4e2d\u548c\u3092\u5fc5\u8981\u3068\u3059\u308b\u30ab\u30eb\u30dc\u30de\u30fc\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002\u305d\u3046\u3057\u306a\u3044\u3068\u3001\u30b7\u30b9\u30c6\u30e0\u304c\u4e0d\u5b89\u5b9a\u306b\u306a\u308a\u307e\u3059\u3002<\/p>

\u898f\u5236\u74b0\u5883\u304c\u5909\u5316\u3057\u3066\u3044\u308b\u305f\u3081\u3001\u30b3\u30f3\u30d7\u30e9\u30a4\u30a2\u30f3\u30b9\u306b\u3064\u3044\u3066\u8a71\u3059\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002\u6b27\u5dde\u59d4\u54e1\u4f1a\u306f\u3053\u308c\u3089\u306e\u6210\u5206\u306b\u5bfe\u3057\u3066\u53b3\u3057\u3044\u53d6\u308a\u7de0\u307e\u308a\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u73fe\u5728\u306eSCCS\u898f\u5247\u3067\u306f\u3001\u9854\u7528\u88fd\u54c1\u306e\u30b3\u30a6\u30b8\u9178\u306f\u6b63\u78ba\u306b1%\u306b\u5236\u9650\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u3001\u9854\u7528\u30af\u30ea\u30fc\u30e0\u3067\u306f2%\u306b\u4e0a\u9650\u304c\u8a2d\u3051\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u6570\u5024\u3092\u4e0a\u56de\u308b\u3068\u3001\u7a0e\u95a2\u304c\u30b3\u30f3\u30c6\u30ca\u3092\u5dee\u3057\u62bc\u3055\u3048\u307e\u3059\u3002\u5f53\u793e\u306e\u6210\u5206\u306f\u3053\u308c\u3089\u306e\u53b3\u683c\u306a\u7d14\u5ea6\u57fa\u6e96\u3092\u6e80\u305f\u3057\u3066\u304a\u308a\u3001\u6cd5\u7684\u306a\u6700\u5927\u5024\u3067\u5b8c\u5168\u306b\u5b89\u5168\u306b\u51e6\u65b9\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p>

\u6709\u52b9\u6210\u5206\u3092\u72ec\u7acb\u3057\u305f\u5909\u6570\u306e\u3088\u3046\u306b\u6271\u3046\u306e\u3092\u3084\u3081\u307e\u3057\u3087\u3046\u3002\u305d\u308c\u3089\u306f\u76f8\u4e92\u4f5c\u7528\u3057\u307e\u3059\u3002\u30d3\u30fc\u30ab\u30fc\u306e\u4e2d\u3067\u4e92\u3044\u306b\u4f1a\u8a71\u3057\u307e\u3059\u3002\u5c0f\u58f2\u68da\u30672\u5e74\u9593\u5b9f\u969b\u306b\u6301\u7d9a\u3059\u308b\u7f8e\u767d\u30af\u30ea\u30fc\u30e0\u304c\u5fc5\u8981\u306a\u5834\u5408\u306f\u3001\u7d71\u5408\u3055\u308c\u305f\u51e6\u65b9\u6226\u7565\u304c\u5fc5\u8981\u3067\u3059\u3002\u6700\u3082\u30af\u30ea\u30fc\u30f3\u306a\u539f\u6599\u3092\u8abf\u9054\u3057\u3001\u5316\u5b66\u7684\u30b7\u30fc\u30eb\u30c9\u3092\u69cb\u7bc9\u3057\u3001pH\u5236\u9650\u3092\u5c0a\u91cd\u3057\u3066\u304f\u3060\u3055\u3044\u3002\u5b89\u5b9a\u6027\u8a66\u9a13\u306f\u5408\u683c\u3057\u3001\u9867\u5ba2\u306f\u652f\u6255\u3063\u305f\u5206\u306e\u8f1d\u304f\u808c\u3092\u624b\u306b\u5165\u308c\u308b\u3067\u3057\u3087\u3046\u3002<\/p>

\u51e6\u65b9\u30c7\u30fc\u30bf\u3067\u53c2\u7167\u3055\u308c\u305f\u6587\u732e\uff1a<\/p>

  1. SCCS\uff08\u6d88\u8cbb\u8005\u5b89\u5168\u79d1\u5b66\u59d4\u54e1\u4f1a\uff09\u3002(2022)\u3002\u5316\u7ca7\u54c1\u4e2d\u306e\u30b3\u30a6\u30b8\u9178\u306b\u95a2\u3059\u308b\u610f\u898b\u3002SCCS\/1637\/21\u3002<\/li>\n\n
  2. SCCS\uff08\u6d88\u8cbb\u8005\u5b89\u5168\u79d1\u5b66\u59d4\u54e1\u4f1a\uff09\u3002(2023)\u3002\u5316\u7ca7\u54c1\u4e2d\u306e\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u304a\u3088\u3073\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u306b\u95a2\u3059\u308b\u610f\u898b\u3002SCCS\/1642\/22\u3002<\/li>\n\n
  3. Garcia-Jimenez, A., et al. (2016). \u30a2\u30eb\u30d5\u30a1\u304a\u3088\u3073\u30d9\u30fc\u30bf-\u30a2\u30eb\u30d6\u30c1\u30f3\u306b\u5bfe\u3059\u308b\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306e\u4f5c\u7528\uff1a\u901f\u5ea6\u8ad6\u7684\u7814\u7a76\u3002Postepy Dermatologii i Alergologii, 33(4), 273-278\u3002<\/li><\/ol>","protected":false},"excerpt":{"rendered":"

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