{"id":11028,"date":"2025-12-03T06:29:04","date_gmt":"2025-12-03T06:29:04","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=11028"},"modified":"2026-07-14T07:30:32","modified_gmt":"2026-07-14T07:30:32","slug":"alpha-arbutin-the-modern-approach-to-brightening-and-hyperpigmentation","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/ja\/alpha-arbutin-the-modern-approach-to-brightening-and-hyperpigmentation\/","title":{"rendered":"\u30a2\u30eb\u30d5\u30a1\u30a2\u30eb\u30d6\u30c1\u30f3\uff1a\u7f8e\u767d\u3068\u8272\u7d20\u6c88\u7740\u306b\u5bfe\u3059\u308b\u73fe\u4ee3\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1"},"content":{"rendered":"<p>\u306a\u305c\u3001\u9ad8\u6fc3\u5ea6\u306e\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u3084\u30d3\u30bf\u30df\u30f3C\u3092\u808c\u306b\u5857\u5e03\u3057\u3066\u3082\u3001\u30b7\u30df\u306f\u518d\u767a\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u307b\u3068\u3093\u3069\u306e\u51e6\u65b9\u958b\u767a\u8005\u306f\u3001\u6d88\u8cbb\u8005\u306e\u7d2b\u5916\u7dda\u5bfe\u7b56\u306e\u7fd2\u6163\u3092\u8cac\u3081\u307e\u3059\u3002\u771f\u306e\u539f\u56e0\u306f\u3001\u6709\u52b9\u6210\u5206\u81ea\u4f53\u306e\u69cb\u9020\u7684\u306a\u69cb\u6210\u306b\u3042\u308b\u3053\u3068\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002\u7f8e\u767d\u5206\u5b50\u306e\u5316\u5b66\u7d50\u5408\u304c\u5f31\u3044\u5834\u5408\u3001\u808c\u8868\u9762\u306e\u9175\u7d20\u306b\u3088\u3063\u3066\u3001\u8272\u7d20\u751f\u6210\u5de5\u5834\u306b\u5230\u9054\u3059\u308b\u524d\u306b\u5206\u89e3\u3055\u308c\u3066\u3057\u307e\u3044\u307e\u3059\u3002<\/p><p>\u30b7\u30df\u3092\u304d\u308c\u3044\u306b\u89e3\u6d88\u3057\u305f\u3044\u306e\u3067\u3042\u308c\u3070\u3001\u808c\u8868\u9762\u306e\u9632\u5fa1\u6a5f\u69cb\u3092\u4e57\u308a\u8d8a\u3048\u308b\u3001\u8ce2\u660e\u306a\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u30d5\u30ea\u30fc\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u304c\u5fc5\u8981\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u304c\u57fa\u6e96\u3092\u5f15\u304d\u4e0a\u3052\u307e\u3059\u3002Shaanxi Huatai Bio-Fine Chemicals Co.\u306e\u88fd\u9020\u30c1\u30fc\u30e0\u3068\u3057\u3066\u3001\u3053\u306e\u7279\u5b9a\u306e\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c9\u7d50\u5408\u304c\u3001\u53e4\u3044\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u306b\u95a2\u9023\u3059\u308b\u6bd2\u6027\u306e\u3042\u308b\u7d30\u80de\u640d\u50b7\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u306a\u304f\u3001\u5b89\u5168\u306b\u8272\u7d20\u5408\u6210\u3092\u963b\u5bb3\u3059\u308b\u65b9\u6cd5\u3092\u5206\u6790\u3057\u307e\u3059\u3002<\/p><h2 class=\"wp-block-heading\" id=\"h-the-alpha-vs-beta-trap-a-structural-reality-check\">\u03b1\u3068\u03b2\u306e\u7f60\uff1a\u69cb\u9020\u7684\u306a\u73fe\u5b9f\u78ba\u8a8d<\/h2><p>\u591a\u304f\u306e\u8cfc\u8cb7\u62c5\u5f53\u8005\u306f\u3001\u5b89\u4fa1\u306a\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u3092\u8cfc\u5165\u3057\u3066\u3001\u30d7\u30ec\u30df\u30a2\u30e0\u306a\u7d50\u679c\u3092\u671f\u5f85\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u306f\u5927\u304d\u306a\u9593\u9055\u3044\u3067\u3059\u3002\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u3068\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u5149\u5b66\u7570\u6027\u4f53\u3067\u3059\u3002\u5316\u5b66\u5f0f\u306f\u540c\u3058\u3067\u3059\u304c\u3001\u7a7a\u9593\u7684\u306a\u914d\u7f6e\u304c\u3059\u3079\u3066\u3092\u5909\u3048\u307e\u3059\u3002<\/p><p>\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u03b2-\u30b0\u30eb\u30b3\u30b7\u30c9\u7d50\u5408\u3092\u7279\u5fb4\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u808c\u8868\u9762\u306e\u7d30\u83cc\u306f\u3001\u3053\u306e\u7d50\u5408\u3092\u5bb9\u6613\u306b\u5206\u89e3\u3057\u3001\u808c\u8868\u9762\u306b\u672a\u7cbe\u88fd\u306e\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u3092\u653e\u51fa\u3057\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u5373\u5ea7\u306e\u8d64\u307f\u3084\u30d4\u30ea\u30d4\u30ea\u611f\u304c\u751f\u3058\u307e\u3059\u3002\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u03b1-\u30b0\u30eb\u30b3\u30b7\u30c9\u7d50\u5408\u3092\u5229\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u69cb\u6210\u306f\u3001\u8868\u9762\u9175\u7d20\u306b\u3088\u308b\u5206\u89e3\u306b\u62b5\u6297\u3057\u3001\u30b7\u30df\u304c\u5b9f\u969b\u306b\u5f62\u6210\u3055\u308c\u308b\u8868\u76ae\u5c64\u306e\u5965\u6df1\u304f\u307e\u3067\u5206\u5b50\u5168\u4f53\u304c\u6d78\u900f\u3059\u308b\u3053\u3068\u3092\u53ef\u80fd\u306b\u3057\u307e\u3059\u3002<\/p><p>\u5de5\u5834\u73fe\u5834\u3067\u3053\u308c\u3089\u306e\u6280\u8853\u7684\u7279\u6027\u304c\u3069\u306e\u3088\u3046\u306b\u6bd4\u8f03\u3055\u308c\u308b\u304b\u3092\u898b\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p><h3 class=\"wp-block-heading\" id=\"h-active-ingredient-raw-material-comparison\">\u6709\u52b9\u6210\u5206\u539f\u6599\u6bd4\u8f03<\/h3><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><td><strong>\u30d1\u30e9\u30e1\u30fc\u30bf<\/strong><\/td><td><strong>\u8d85\u9ad8\u7d14\u5ea6\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3<\/strong><\/td><td><strong>\u6a19\u6e96\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3<\/strong><\/td><\/tr><\/thead><tbody><tr><td><strong>\u5916\u89b3<\/strong><\/td><td>\u767d\u8272\u7d50\u6676\u6027\u7c89\u672b<\/td><td>\u767d\u8272\u7d50\u6676\u6027\u7c89\u672b<\/td><\/tr><tr><td><strong>\u30a2\u30c3\u30bb\u30a4\u7d14\u5ea6\uff08HPLC\uff09<\/strong><\/td><td>0%\u4ee5\u4e0a<\/td><td>0\u30d1\u30fc\u30bb\u30f3\u30c8\u4ee5\u4e0a<\/td><\/tr><tr><td><strong>\u878d\u70b9\u7bc4\u56f2<\/strong><\/td><td>202\uff5e206\u2103<\/td><td>175\uff5e180\u2103<\/td><\/tr><tr><td><strong>\u6bd4\u65cb\u5149\u5ea6<\/strong><\/td><td>+174\uff5e+184\u5ea6<\/td><td>-64\uff5e-68\u5ea6<\/td><\/tr><tr><td><strong>\u6c34\u6eb6\u6027\uff0820\u2103\uff09<\/strong><\/td><td>100 percent soluble (Up to 150 g\/L)<\/td><td>\u53ef\u6eb6\uff08\u6700\u592750 g\/L\uff09<\/td><\/tr><tr><td><strong>\u91cd\u91d1\u5c5e<\/strong><\/td><td>10 ppm \u4ee5\u4e0b<\/td><td>10 ppm \u4ee5\u4e0b<\/td><\/tr><tr><td><strong>\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u6b8b\u6e23<\/strong><\/td><td>10 ppm\u672a\u6e80\uff08\u8d85\u5b89\u5168\uff09<\/td><td>50 ppm\u4ee5\u4e0a\uff08\u4e0d\u5b89\u5b9a\uff09<\/td><\/tr><\/tbody><\/table><\/figure><p>\u5149\u5b66\u56de\u8ee2\u5ea6\uff08+174\u5ea6\u5bfe-64\u5ea6\uff09\u306e\u5927\u304d\u306a\u5dee\u306f\u3001\u7d14\u7c8b\u306a\u03b1\u7d50\u5408\u3092\u78ba\u8a8d\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u3055\u3089\u306b\u3001\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u3001\u03b2\u30b0\u30ec\u30fc\u30c9\u3088\u308a\u3082\u5ba4\u6e29\u306e\u6c34\u306b3\u500d\u3088\u304f\u6eb6\u89e3\u3059\u308b\u305f\u3081\u3001\u6a19\u6e96\u7684\u306a\u30b3\u30fc\u30eb\u30c9\u30d7\u30ed\u30bb\u30b9\u88fd\u9020\u30bf\u30f3\u30af\u3067\u306e\u53d6\u308a\u6271\u3044\u304c\u975e\u5e38\u306b\u5bb9\u6613\u3067\u3059\u3002<\/p><h2 class=\"wp-block-heading\" id=\"h-formulation-strategy-the-high-stability-translucent-serum\">\u88fd\u5264\u6226\u7565\uff1a\u9ad8\u5b89\u5b9a\u6027\u900f\u660e\u7f8e\u5bb9\u6db2<\/h2><p>\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u6c34\u306b\u5373\u5ea7\u306b\u6eb6\u89e3\u3059\u308b\u305f\u3081\u3001\u51e6\u65b9\u958b\u767a\u8005\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u6271\u3044\u3084\u3059\u3044\u6210\u5206\u3067\u3059\u3002\u3057\u304b\u3057\u3001\u6975\u7aef\u306a\u71b1\u3084\u52a0\u6c34\u5206\u89e3\u306b\u306f\u5f31\u3044\u3067\u3059\u3002\u30d0\u30c3\u30c1\u6e29\u5ea6\u304c70\u2103\u3092\u8d85\u3048\u3066\u9577\u6642\u9593\u7d9a\u3044\u305f\u308a\u3001\u6700\u7d42\u51e6\u65b9\u306epH\u304c4.5\u3092\u4e0b\u56de\u3063\u305f\u308a\u3059\u308b\u3068\u3001\u03b1\u7d50\u5408\u304c\u7834\u58ca\u3055\u308c\u3001\u30d0\u30c3\u30c1\u5185\u306b\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u304c\u3086\u3063\u304f\u308a\u3068\u653e\u51fa\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u4fdd\u5b58\u5bff\u547d\u304c\u640d\u306a\u308f\u308c\u3001\u7f8e\u5bb9\u6db2\u304c\u6fc1\u3063\u305f\u9ec4\u8272\u306b\u306a\u308a\u307e\u3059\u3002<\/p><p>\u3053\u3053\u306b\u30012\u30d1\u30fc\u30bb\u30f3\u30c8\u306e\u30bf\u30fc\u30b2\u30c3\u30c8\u7f8e\u767d\u7f8e\u5bb9\u6db2\u306e\u305f\u3081\u306e\u3001\u30c6\u30b9\u30c8\u6e08\u307f\u306e\u88fd\u9020\u30b0\u30ec\u30fc\u30c9\u306e\u51e6\u65b9\u30d5\u30ec\u30fc\u30e0\u30ef\u30fc\u30af\u3092\u793a\u3057\u307e\u3059\u3002<\/p><h3 class=\"wp-block-heading\" id=\"h-advanced-alpha-pigment-control-serum-formula\">\u9ad8\u5ea6\u306a\u03b1\u8272\u7d20\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u7f8e\u5bb9\u6db2\u51e6\u65b9<\/h3><figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><thead><tr><td><strong>\u76f8<\/strong><\/td><td><strong>\u6750\u6599<\/strong><\/td><td><strong>\u95a2\u6570<\/strong><\/td><td><strong>\u91cd\u91cf\u30d1\u30fc\u30bb\u30f3\u30c8<\/strong><\/td><\/tr><\/thead><tbody><tr><td><strong>Phase A<\/strong><\/td><td>\u8131\u30a4\u30aa\u30f3\u6c34<\/td><td>\u30b3\u30a2\u6eb6\u5a92\u5a92\u4f53<\/td><td>Q.S. 100\u307e\u3067<\/td><\/tr><tr><td><strong>Phase A<\/strong><\/td><td>\u30b0\u30ea\u30bb\u30ea\u30f3<\/td><td>\u4fdd\u6e7f\u5264<\/td><td>4.00<\/td><\/tr><tr><td><strong>Phase A<\/strong><\/td><td><strong>\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u30d1\u30a6\u30c0\u30fc\uff0899%\uff09<\/strong><\/td><td>\u30b3\u30a2\u8272\u7d20\u30b3\u30f3\u30c8\u30ed\u30fc\u30e9\u30fc<\/td><td>2.00<\/td><\/tr><tr><td><strong>Phase B<\/strong><\/td><td>\u30d6\u30c1\u30ec\u30f3\u30b0\u30ea\u30b3\u30fc\u30eb<\/td><td>\u30c6\u30af\u30b9\u30c1\u30e3\u30fc\u30a8\u30f3\u30cf\u30f3\u30b5\u30fc<\/td><td>5.00<\/td><\/tr><tr><td><strong>Phase B<\/strong><\/td><td>Niacinamide (Vitamin B3)<\/td><td>\u76f8\u4e57\u30ad\u30e3\u30ea\u30a2\u30d6\u30ed\u30c3\u30ab\u30fc<\/td><td>2.00<\/td><\/tr><tr><td><strong>Phase C<\/strong><\/td><td>\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0<\/td><td>\u7c98\u5ea6\/\u4fdd\u6e7f\u819c<\/td><td>0.30<\/td><\/tr><tr><td><strong>Phase D<\/strong><\/td><td>\u30d5\u30a7\u30ce\u30ad\u30b7\u30a8\u30bf\u30ce\u30fc\u30eb<\/td><td>\u4fdd\u5b58\u5264\u6210\u5206<\/td><td>0.60<\/td><\/tr><\/tbody><\/table><\/figure><h3 class=\"wp-block-heading\" id=\"h-critical-processing-instructions\">\u91cd\u8981\u5de5\u7a0b\u6307\u793a<\/h3><ol start=\"1\" class=\"wp-block-list\"><li>\u30d5\u30a7\u30fc\u30baA\u306e\u7cbe\u88fd\u6c34\u3068\u30b0\u30ea\u30bb\u30ea\u30f3\u3092\u5ba4\u6e29\u3067\u30e1\u30a4\u30f3\u6df7\u5408\u30bf\u30f3\u30af\u306b\u6295\u5165\u3057\u307e\u3059\u3002<\/li>\n\n<li>\u7d14\u7c8b\u306a\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u7d50\u6676\u3092\u3001\u4e2d\u7a0b\u5ea6\u306e\u30d1\u30c9\u30eb\u30df\u30ad\u30b5\u30fc\uff08400 rpm\uff09\u3067\u3086\u3063\u304f\u308a\u3068\u6dfb\u52a0\u3057\u307e\u3059\u3002\u767d\u3044\u7c89\u672b\u306f\u3001\u71b1\u3092\u52a0\u3048\u308b\u3053\u3068\u306a\u304f5\u5206\u4ee5\u5185\u306b\u5b8c\u5168\u306b\u6eb6\u89e3\u3057\u3001\u900f\u660e\u3067\u6f84\u3093\u3060\u6db2\u4f53\u306b\u306a\u308a\u307e\u3059\u3002<\/li>\n\n<li>\u30d5\u30a7\u30fc\u30baB\u306e\u30d6\u30c1\u30ec\u30f3\u30b0\u30ea\u30b3\u30fc\u30eb\u3068\u30ca\u30a4\u30a2\u30b7\u30f3\u30a2\u30df\u30c9\u3092\u6dfb\u52a0\u3057\u307e\u3059\u300210\u5206\u9593\u652a\u62cc\u3057\u3001\u5b8c\u5168\u306b\u5747\u4e00\u306b\u3057\u307e\u3059\u3002<\/li>\n\n<li>\u4e8b\u524d\u306b\u6eb6\u89e3\u3057\u305f\u30d2\u30a2\u30eb\u30ed\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u30b2\u30eb\u30d5\u30a7\u30fc\u30ba\u3092\u6dfb\u52a0\u3057\u3001\u6ed1\u3089\u304b\u3067\u3057\u3063\u3068\u308a\u3068\u3057\u305f\u30af\u30c3\u30b7\u30e7\u30f3\u30c6\u30af\u30b9\u30c1\u30e3\u30fc\u3092\u69cb\u7bc9\u3057\u307e\u3059\u3002<\/li>\n\n<li>\u30d5\u30a7\u30fc\u30baD\u306e\u9632\u8150\u5264\u3092\u6dfb\u52a0\u3057\u307e\u3059\u3002pH\u30e1\u30fc\u30bf\u30fc\u3092\u78ba\u8a8d\u3057\u307e\u3059\u30025.3\u304b\u30896.5\u306e\u53b3\u5bc6\u306a\u30bf\u30fc\u30b2\u30c3\u30c8\u30a6\u30a3\u30f3\u30c9\u30a6\u3092\u7dad\u6301\u3057\u307e\u3059\u3002pH\u304c\u4f4e\u3059\u304e\u308b\u5834\u5408\u306f\u3001\u5e0c\u91c8\u3057\u305f\u6c34\u9178\u5316\u30ca\u30c8\u30ea\u30a6\u30e0\u30d0\u30c3\u30d5\u30a1\u30fc\u3092\u5c11\u91cf\u6dfb\u52a0\u3057\u3066\u51e6\u65b9\u3092\u5b89\u5b9a\u3055\u305b\u307e\u3059\u3002<\/li><\/ol><h2 class=\"wp-block-heading\" id=\"h-lab-data-the-tyrosinase-inhibition-benchmark\">\u30e9\u30dc\u30c7\u30fc\u30bf\uff1a\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u306e\u30d9\u30f3\u30c1\u30de\u30fc\u30af<\/h2><p>\u03b1\u578b\u306f\u3001\u03b2\u578b\u3088\u308a\u3082\u5b9f\u969b\u306b\u8272\u7d20\u6591\u306b\u5f37\u304f\u4f5c\u7528\u3059\u308b\u306e\u3067\u3057\u3087\u3046\u304b\uff1fIC50\u5024\u3001\u3059\u306a\u308f\u3061\u808c\u306e\u30b7\u30df\u306e\u539f\u56e0\u3068\u306a\u308b\u9175\u7d20\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u306e50%\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u6709\u52b9\u6210\u5206\u306e\u6b63\u78ba\u306a\u6fc3\u5ea6\u3092\u6e2c\u5b9a\u3057\u307e\u3057\u305f\u3002\u6570\u5024\u304c\u4f4e\u3044\u307b\u3069\u3001\u5b9f\u8cea\u7684\u306a\u7d50\u679c\u3092\u5f97\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u91cf\u304c\u5c11\u306a\u304f\u3066\u6e08\u307f\u307e\u3059\u3002<\/p><p>\u5f53\u793e\u306e\u5b9f\u9a13\u5ba4\u3067\u306e\u7d30\u80de\u682a\u8a66\u9a13\u3067\u306f\u3001\u4ee5\u4e0b\u306e\u6bd4\u8f03\u52b9\u7387\u8ffd\u8de1\u6307\u6a19\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002<\/p><pre class=\"wp-block-code\"><code>\u30c1\u30ed\u30b7\u30ca\u30fc\u30bc\u963b\u5bb3\u52b9\u529b\uff08IC50\u6307\u6570\u3001\u30de\u30a4\u30af\u30ed\u30b0\u30e9\u30e0\/mL\uff09\uff1a\n<\/code><\/pre><p>\u3053\u306e\u5dee\u3092\u898b\u3066\u304f\u3060\u3055\u3044\u3002\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306f\u3001\u03b2-\u30a2\u30eb\u30d6\u30c1\u30f3\u306e10\u5206\u306e1\u306e\u6fc3\u5ea6\u3067\u8272\u7d20\u751f\u6210\u30e9\u30a4\u30f3\u3092\u30d6\u30ed\u30c3\u30af\u3057\u307e\u3059\u3002\u3053\u306e\u6975\u3081\u3066\u9ad8\u3044\u539f\u6599\u52b9\u529b\u306f\u3001\u308f\u305a\u304b2.0\u30d1\u30fc\u30bb\u30f3\u30c8\u306e\u6a19\u6e96\u7684\u306a\u5316\u7ca7\u54c1\u7528\u91cf\u3067\u3001\u5408\u6210\u5316\u5b66\u30d4\u30fc\u30ea\u30f3\u30b0\u5264\u306b\u4e00\u822c\u7684\u306b\u898b\u3089\u308c\u308b\u8d64\u307f\u3001\u523a\u6fc0\u3001\u307e\u305f\u306f\u7d30\u80de\u6bd2\u6027\u306a\u3057\u306b\u3001\u8fc5\u901f\u306a\u808c\u306e\u8272\u8abf\u5747\u4e00\u5316\u3092\u5b9f\u73fe\u3067\u304d\u308b\u3053\u3068\u3092\u610f\u5473\u3057\u307e\u3059\u3002<\/p><h2 class=\"wp-block-heading\" id=\"h-global-regulatory-compliance-and-sourcing-guidelines\">\u30b0\u30ed\u30fc\u30d0\u30eb\u898f\u5236\u9075\u5b88\u3068\u8abf\u9054\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3<\/h2><p>\u65b0\u3057\u3044\u7f8e\u767d\u7f8e\u5bb9\u6db2\u3092\u88fd\u9020\u306b\u79fb\u884c\u3059\u308b\u524d\u306b\u3001\u539f\u6599\u306e\u914d\u5408\u91cf\u304c\u6700\u65b0\u306e\u5730\u57df\u5b89\u5168\u57fa\u6e96\u3092\u6e80\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p><ul class=\"wp-block-list\"><li><strong>\u6b27\u5dde\u9023\u5408\uff08SCCS\uff09\uff1a<\/strong> \u6d88\u8cbb\u8005\u5b89\u5168\u79d1\u5b66\u59d4\u54e1\u4f1a\u306f\u3001\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306e\u6700\u5927\u6fc3\u5ea6\u3092\u3001\u9854\u7528\u30af\u30ea\u30fc\u30e0\u3067\u306f2.0\u30d1\u30fc\u30bb\u30f3\u30c8\u3001\u30dc\u30c7\u30a3\u30ed\u30fc\u30b7\u30e7\u30f3\u3067\u306f0.5\u30d1\u30fc\u30bb\u30f3\u30c8\u306b\u5236\u9650\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n\n<li><strong>\u7c73\u56fd\uff08FDA\/PCPC\uff09\uff1a<\/strong> \u5b89\u5168\u306a\u5316\u7ca7\u54c1\u6709\u52b9\u6210\u5206\u3068\u3057\u3066\u5b8c\u5168\u306b\u30ea\u30b9\u30c8\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u5316\u7ca7\u54c1\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u5185\u306b\u7559\u307e\u308b\u9650\u308a\u3001\u5e02\u8ca9\u306e\u30cf\u30a4\u30c9\u30ed\u30ad\u30ce\u30f3\u88fd\u5264\u306b\u95a2\u9023\u3059\u308b\u53b3\u3057\u3044\u533b\u85ac\u54c1\u8868\u793a\u306e\u5236\u7d04\u3092\u56de\u907f\u3067\u304d\u307e\u3059\u3002<\/li>\n\n<li><strong>\u4e2d\u56fd\uff08IECIC 2021\uff09\uff1a<\/strong> \u627f\u8a8d\u3055\u308c\u305f\u5316\u7ca7\u54c1\u539f\u6599\u306e\u5b89\u5168\u5728\u5eab\u30ea\u30b9\u30c8\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li><\/ul><p>\u73fe\u4ee3\u306e\u30b9\u30ad\u30f3\u30b1\u30a2\u6d88\u8cbb\u8005\u306f\u3001\u66d6\u6627\u306a\u30de\u30fc\u30b1\u30c6\u30a3\u30f3\u30b0\u4e3b\u5f35\u3067\u306f\u306a\u304f\u3001\u9ad8\u7d14\u5ea6\u306e\u79d1\u5b66\u306b\u88cf\u6253\u3061\u3055\u308c\u305f\u81e8\u5e8a\u7d50\u679c\u3092\u6c42\u3081\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u7d50\u6676\u6027\u6709\u52b9\u6210\u5206\u306e\u512a\u308c\u305f\u5b89\u5168\u6027\u3068\u5b89\u5b9a\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u3088\u308a\u3001\u5e02\u5834\u306e\u671f\u5f85\u306b\u6b63\u78ba\u306b\u5fdc\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/p><p>\u65e2\u5b58\u306e\u8272\u7d20\u6c88\u7740\u30e9\u30a4\u30f3\u3092\u30a2\u30c3\u30d7\u30b0\u30ec\u30fc\u30c9\u3059\u308b\u5834\u5408\u3067\u3082\u3001\u65b0\u3057\u3044\u30b5\u30f3\u30b1\u30a2\u5f8c\u306e\u30a8\u30c3\u30bb\u30f3\u30b9\u3092\u8a2d\u8a08\u3059\u308b\u5834\u5408\u3067\u3082\u3001\u539f\u6599\u306e\u7d14\u5ea6\u304c\u5546\u696d\u7684\u306a\u30d0\u30c3\u30c1\u306e\u5b89\u5b9a\u6027\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002\u5f53\u793e\u3001Shaanxi Huatai Bio-Fine Chemicals Co.\u306f\u3001\u30d7\u30ec\u30df\u30a2\u30e0\u306a\u5316\u7ca7\u54c1\u6709\u52b9\u6210\u5206\u3092\u88fd\u9020\u3057\u3001\u4e16\u754c\u4e2d\u306eR&amp;D\u65bd\u8a2d\u306b\u4f9b\u7d66\u3057\u3066\u3044\u307e\u3059\u3002\u5f53\u793e\u306e\u30a8\u30f3\u30b8\u30cb\u30a2\u30ea\u30f3\u30b0\u30c1\u30fc\u30e0\u306b\u9023\u7d61\u3057\u3066\u3001\u7814\u7a76\u6240\u3067\u306e\u30d9\u30f3\u30c1\u30c8\u30e9\u30a4\u30a2\u30eb\u7528\u306e\u88fd\u54c1\u30c6\u30b9\u30c8\u30b5\u30f3\u30d7\u30eb\u3092\u30ea\u30af\u30a8\u30b9\u30c8\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/p><h3 class=\"wp-block-heading\" id=\"h-referenced-literature-in-this-article\">\u672c\u8a18\u4e8b\u3067\u53c2\u7167\u3055\u308c\u305f\u6587\u732e\uff1a<\/h3><ul class=\"wp-block-list\"><li><em>\u30b8\u30e3\u30fc\u30ca\u30eb\u30fb\u30aa\u30d6\u30fb\u30c0\u30fc\u30de\u30c8\u30ed\u30b8\u30ab\u30eb\u30fb\u30b5\u30a4\u30a8\u30f3\u30b9\uff1a<\/em> \u300c\u57f9\u990a\u30d2\u30c8\u30e1\u30e9\u30ce\u30fc\u30de\u7d30\u80de\u304a\u3088\u3073\u4e09\u6b21\u5143\u30d2\u30c8\u76ae\u819a\u30e2\u30c7\u30eb\u306b\u304a\u3051\u308b\u03b1-\u30a2\u30eb\u30d6\u30c1\u30f3\u306e\u30e1\u30e9\u30ce\u30b8\u30a7\u30cd\u30b7\u30b9\u306b\u5bfe\u3059\u308b\u963b\u5bb3\u52b9\u679c\u3002\u300d<\/li>\n\n<li><em>International Journal of Cosmetic Science\uff1a<\/em> \u30a2\u30eb\u30d5\u30a1\u30b0\u30eb\u30b3\u30b7\u30c9\u3068\u30d9\u30fc\u30bf\u30b0\u30eb\u30b3\u30b7\u30c9\u306e\u30a2\u30eb\u30d6\u30c1\u30f3\u7570\u6027\u4f53\u306e\u5b89\u5b9a\u6027\u3068\u7f8e\u767d\u52b9\u679c\u306e\u6bd4\u8f03\u7814\u7a76\u3002<\/li>\n\n<li><em>\u6d88\u8cbb\u8005\u5b89\u5168\u79d1\u5b66\u59d4\u54e1\u4f1a (SCCS):<\/em> \u5316\u7ca7\u54c1\u306b\u304a\u3051\u308b\u30a2\u30eb\u30d5\u30a1\u30a2\u30eb\u30d6\u30c1\u30f3\u304a\u3088\u3073\u30d9\u30fc\u30bf\u30a2\u30eb\u30d6\u30c1\u30f3\u306e\u5b89\u5168\u6027\u306b\u95a2\u3059\u308b\u610f\u898b\u3002<\/li><\/ul>","protected":false},"excerpt":{"rendered":"<p>Why do dark spots return even after you dump high percentages of Beta-Arbutin or Vitamin C onto the skin? 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