{"id":14283,"date":"2026-06-26T02:46:00","date_gmt":"2026-06-26T02:46:00","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=14283"},"modified":"2026-06-26T02:50:45","modified_gmt":"2026-06-26T02:50:45","slug":"oil-soluble-brightening-systems-formulating-high-performance-anhydrous-glow-products","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/fr\/oil-soluble-brightening-systems-formulating-high-performance-anhydrous-glow-products\/","title":{"rendered":"Syst\u00e8mes \u00c9claircissants Liposolubles : Formulation de Produits Anhydres Haute Performance pour l'\u00c9clat"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14283\" class=\"elementor elementor-14283\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-de8b38b e-flex e-con-boxed e-con e-parent\" data-id=\"de8b38b\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-02e178c elementor-widget elementor-widget-html\" data-id=\"02e178c\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t  <script type=\"application\/ld+json\">{\n    \"@context\": \"https:\\\/\\\/schema.org\",\n    \"@type\": \"Article\",\n    \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\\\/\\\/glabridinchina.com\\\/oil-soluble-brightening-systems-formulating-high-performance-anhydrous-glow-products\\\/\"\n    },\n    \"headline\": \"Oil-Soluble Brightening Systems: Formulating High-Performance Anhydrous Glow Products\",\n    \"about\": {\n        \"@type\": \"ChemicalSubstance\",\n        \"name\": \"Glabridin\",\n        \"alternateName\": \"\\u5149\\u7518\\u8349\\u5b9a\"\n    },\n    \"publisher\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical\",\n        \"url\": \"https:\\\/\\\/glabridinchina.com\"\n    },\n    \"author\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical Technical Team\"\n    },\n    \"datePublished\": \"2026\",\n    \"description\": \"A technical guide to formulating oil-based and anhydrous brightening products using the 90% oil-soluble glabridin grade \\u2014 covering face oils, lip oils, oil serums, and anhydrous balms, with stability data, active system design, and formulation blueprints.\"\n}<\/script>\n\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n  <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;500;600;700&family=Merriweather:ital,wght@0,400;0,700;1,400&display=swap\" rel=\"stylesheet\">\n\n  <style>\n    :root {\n      --color-bg:           #f9f9f7;\n      --color-surface:      #ffffff;\n      --color-border:       #e5e2d9;\n      --color-text:         #1c1c1a;\n      --color-text-muted:   #6a6760;\n      --color-accent:       #2d5a3d;\n      --color-accent-light: #edf4ef;\n      --color-accent-mid:   #4a7c5f;\n      --color-warn:         #A0522D;\n      --color-warn-light:   #fef0e6;\n      --color-data-bg:      #f3f1ed;\n      --font-heading:       'Merriweather', Georgia, 'Times New Roman', serif;\n      --font-body:          'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Helvetica, Arial, sans-serif;\n      --max-width:          800px;\n      --radius:             6px;\n    }\n\n    *, *::before, *::after { box-sizing: border-box; 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L'absence d'eau r\u00e9duit les risques de stabilit\u00e9 cl\u00e9s, et les syst\u00e8mes en phase huileuse favorisent la partition des actifs lipophiles dans les domaines lipidiques du stratum corneum. Cet article couvre la science de la formulation des syst\u00e8mes \u00e9claircissants liposolubles, le grade de glabridin liposoluble 90%, et des conseils pratiques pour les huiles pour le visage, les huiles \u00e0 l\u00e8vres, les s\u00e9rums huileux et les baumes anhydres.<\/p>\n      <div class=\"byline\">\n        <span><strong>Huatai Bio-Fine Chemical<\/strong> \u2014 fabricant d'actifs cosm\u00e9tiques de haute puret\u00e9 depuis 2008<\/span>\n        <span style=\"color:var(--color-border)\">\u00b7<\/span>\n        <span>Publi\u00e9 2026<\/span>\n      <\/div>\n    <\/header>\n\n    <article class=\"article-body\">\n\n      <p>Les syst\u00e8mes \u00e0 base d'huile et anhydres offrent un environnement de formulation favorable au glabridin. L'absence d'eau r\u00e9duit les risques de stabilit\u00e9 cl\u00e9s, y compris la d\u00e9gradation hydrolytique (qui peut \u00eatre acc\u00e9l\u00e9r\u00e9e dans des conditions alcalines) et les voies d'oxydation catalys\u00e9es par les m\u00e9taux. De plus, les syst\u00e8mes en phase huileuse facilitent la partition des actifs lipophiles dans les domaines lipidiques du stratum corneum, favorisant leur interaction avec la barri\u00e8re cutan\u00e9e.<\/p>\n\n      <h2>Pourquoi la phase huileuse est un environnement tr\u00e8s stable pour le glabridin<\/h2>\n\n      <p>Les principales voies de d\u00e9gradation du glabridin sont associ\u00e9es aux syst\u00e8mes contenant de l'eau :<\/p>\n\n      <p><strong>Oxydation catalys\u00e9e par les m\u00e9taux :<\/strong> Les ions m\u00e9talliques peuvent catalyser la d\u00e9gradation oxydative du glabridin par cycle redox et formation de radicaux libres. Les environnements aqueux peuvent faciliter ce processus en augmentant la mobilit\u00e9 des ions m\u00e9talliques, tandis que les syst\u00e8mes \u00e0 base d'huile r\u00e9duisent ces interactions m\u00e9diatis\u00e9es par les m\u00e9taux, ce qui am\u00e9liore la stabilit\u00e9.<\/p>\n\n      <p><strong>D\u00e9gradation oxydative li\u00e9e aux alcalins :<\/strong> Dans les syst\u00e8mes aqueux, les conditions alcalines peuvent favoriser la d\u00e9gradation oxydative du glabridin en augmentant la r\u00e9activit\u00e9 des groupes ph\u00e9noliques par d\u00e9protonation. Cet effet d\u00e9pendant du pH est moins prononc\u00e9 dans les syst\u00e8mes \u00e0 base d'huile en raison de l'absence d'un environnement d'ionisation aqueuse.<\/p>\n\n      <p>Dans un syst\u00e8me anhydre bien formul\u00e9 avec un syst\u00e8me antioxydant appropri\u00e9, la stabilit\u00e9 du glabridin peut \u00eatre am\u00e9lior\u00e9e par rapport \u00e0 de nombreux syst\u00e8mes \u00e0 base d'\u00e9mulsion, en particulier ceux impliquant des environnements contenant de l'eau et des ions m\u00e9talliques. Par cons\u00e9quent, les huiles pour le visage et les s\u00e9rums anhydres peuvent offrir un environnement plus favorable au maintien de la stabilit\u00e9 dans des conditions de formulation contr\u00f4l\u00e9es.<\/p>\n\n      <h2>Le grade liposoluble 90% : Sp\u00e9cifications techniques<\/h2>\n\n      <p>Les grades de poudre de glabridin standard sont lipophiles mais pr\u00e9sentent une dispersibilit\u00e9 limit\u00e9e dans les huiles v\u00e9g\u00e9tales. Sans traitement appropri\u00e9, le glabridin peut former une suspension qui peut entra\u00eener une s\u00e9dimentation au fil du temps, ce qui est ind\u00e9sirable dans les formulations haut de gamme \u00e0 base d'huile.<\/p>\n\n      <p>Le grade liposoluble 90% de Huatai r\u00e9sout ce probl\u00e8me gr\u00e2ce \u00e0 un <strong>proc\u00e9d\u00e9 de fabrication brevet\u00e9<\/strong> qui restructure la glabridine en <strong>particules sph\u00e9riques uniformes de 50 \u03bcm<\/strong>. Cette modification am\u00e9liore consid\u00e9rablement la dispersibilit\u00e9 dans la phase huileuse.<\/p>\n\n      <h3>Tests de s\u00e9dimentation sur 5 types d'huiles<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Type d'huile test\u00e9<\/th>\n              <th>Glabridin standard (non modifi\u00e9)<\/th>\n              <th>Grade liposoluble 90%<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Huile de cam\u00e9lia<\/td>\n              <td>S\u00e9dimentation visible<\/td>\n              <td>Aucune s\u00e9dimentation visible<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de germe de ma\u00efs<\/td>\n              <td>S\u00e9dimentation visible<\/td>\n              <td>Aucune s\u00e9dimentation visible<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de Torreya<\/td>\n              <td>S\u00e9dimentation visible<\/td>\n              <td>Aucune s\u00e9dimentation visible<\/td>\n            <\/tr>\n            <tr>\n              <td>Torreya:Cam\u00e9lia (1:1)<\/td>\n              <td>S\u00e9dimentation visible<\/td>\n              <td>Aucune s\u00e9dimentation visible<\/td>\n            <\/tr>\n            <tr>\n              <td>Torreya:Cam\u00e9lia (2:1)<\/td>\n              <td>S\u00e9dimentation visible<\/td>\n              <td>Aucune s\u00e9dimentation visible<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>Stabilit\u00e9 au stockage (milieu d'huile de cam\u00e9lia) :<\/strong> Le glabridin standard a montr\u00e9 une s\u00e9dimentation d\u00e8s le premier jour de stockage. Le grade liposoluble n'a montr\u00e9 aucune s\u00e9dimentation visible pendant toute la p\u00e9riode d'observation.<\/p>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/77688fa1-6751-413d-92ad-ef2a1ff6b92c-clean.png\"\n             alt=\"Comparaison c\u00f4te \u00e0 c\u00f4te de la glabridine standard (\u00e0 gauche, s\u00e9dimentation visible) par rapport \u00e0 la qualit\u00e9 de glabridine liposoluble (\u00e0 droite, dispersion claire) dans l&#039;huile de cam\u00e9lia\">\n        <figcaption>Comparaison de la s\u00e9dimentation : glabridin standard (\u00e0 gauche) vs grade de glabridin liposoluble 90% (\u00e0 droite) dans l'huile de cam\u00e9lia. Donn\u00e9es : tests internes Huatai.<\/figcaption>\n      <\/figure>\n\n      <h3>Sp\u00e9cifications du grade<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Param\u00e8tre<\/th>\n              <th>D\u00e9tail<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Teneur en actif<\/td>\n              <td>Glabridin 90%<\/td>\n            <\/tr>\n            <tr>\n              <td>Forme physique<\/td>\n              <td>Poudre blanche<\/td>\n            <\/tr>\n            <tr>\n              <td>Structure des particules<\/td>\n              <td>Particules sph\u00e9riques uniformes de 50 \u03bcm (brevet\u00e9es)<\/td>\n            <\/tr>\n            <tr>\n              <td>Solubilit\u00e9<\/td>\n              <td>Liposoluble \u2014 dispersion directe dans les huiles v\u00e9g\u00e9tales<\/td>\n            <\/tr>\n            <tr>\n              <td>Niveau d'utilisation recommand\u00e9<\/td>\n              <td>~0,2 % dans la formulation finie<\/td>\n            <\/tr>\n            <tr>\n              <td>dur\u00e9e de conservation<\/td>\n              <td>24 mois<\/td>\n            <\/tr>\n            <tr>\n              <td>Statut COSMOS<\/td>\n              <td>Agr\u00e9\u00e9<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout\">\n        <p><strong>Note sur le niveau d'utilisation :<\/strong> Le niveau d'utilisation recommand\u00e9 pour le grade liposoluble est d'environ 0,2 % dans les formulations finies, ce qui correspond au niveau actif cible de glabridin dans les syst\u00e8mes \u00e0 base d'huile. Ce grade est con\u00e7u et optimis\u00e9 pour des performances dans cette plage d'utilisation. Les niveaux d'utilisation en dehors de la plage recommand\u00e9e doivent \u00eatre \u00e9valu\u00e9s par des tests de formulation et de stabilit\u00e9.<\/p>\n      <\/div>\n\n      <h2>Conception du syst\u00e8me actif pour le blanchiment \u00e0 base d'huile<\/h2>\n\n      <h3>L'actif principal : Glabridin liposoluble 90% \u00e0 ~0,2 %<\/h3>\n\n      <p>Le glabridin exerce son activit\u00e9 par plusieurs voies, notamment l'inhibition de la tyrosinase, l'activit\u00e9 anti-inflammatoire et le pi\u00e9geage des esp\u00e8ces r\u00e9actives de l'oxyg\u00e8ne (ROS) antioxydantes. Dans les syst\u00e8mes \u00e0 base d'huile, sa nature lipophile favorise une bonne compatibilit\u00e9 avec les environnements riches en lipides :<\/p>\n      <ul>\n        <li><strong>Inhibition de la tyrosinase :<\/strong> contribue \u00e0 la r\u00e9gulation de la synth\u00e8se de m\u00e9lanine et \u00e0 l'activit\u00e9 \u00e9claircissante de la peau<\/li>\n        <li><strong>Activit\u00e9 anti-inflammatoire :<\/strong> peut aider \u00e0 r\u00e9duire la pigmentation li\u00e9e \u00e0 l'inflammation (processus associ\u00e9s au PIH)<\/li>\n        <li><strong>Antioxydant :<\/strong> pi\u00e9geage des radicaux dans la phase lipidique, agissant en synergie avec les syst\u00e8mes antioxydants \u00e0 base de tocoph\u00e9rol<\/li>\n      <\/ul>\n\n      <h3>S\u00e9lection des co-actifs pour les syst\u00e8mes \u00e0 base d'huile<\/h3>\n\n      <p>Les syst\u00e8mes \u00e0 base d'huile limitent la s\u00e9lection des co-actifs aux actifs liposolubles ou compatibles avec les lipides. Les suivants compl\u00e8tent efficacement le glabridin dans la phase huileuse :<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Co-actif<\/th>\n              <th>Fonction<\/th>\n              <th>Notes<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td><strong>Bakuchiol<\/strong><\/td>\n              <td>Activit\u00e9 anti-\u00e2ge de type r\u00e9tinol (soutien du collag\u00e8ne, modulation des MMP)<\/td>\n              <td>Aucune d\u00e9pendance au pH ; compatible dans tous les syst\u00e8mes de formulation ; largement utilis\u00e9 dans le positionnement naturel<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Ascorbate de Tetrahexyld\u00e9cyle (THDC)<\/strong><\/td>\n              <td>Vitamine C liposoluble \u2014 soutien antioxydant et activit\u00e9 li\u00e9e au blanchiment<\/td>\n              <td>D\u00e9riv\u00e9 liposoluble tr\u00e8s stable avec une bonne compatibilit\u00e9 en phase lipidique<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Palmitate d'Ascorbyle<\/strong><\/td>\n              <td>Vitamine C liposoluble \u2014 fonction antioxydante<\/td>\n              <td>Profil de conversion plus lent ; fonctionne principalement comme antioxydant auxiliaire<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Extrait de romarin<\/strong> (standardis\u00e9 pour l'acide carnosique)<\/td>\n              <td>Antioxydant naturel<\/td>\n              <td>Ingr\u00e9dient antioxydant compatible COSMOS ; alternative ou compl\u00e9ment aux antioxydants synth\u00e9tiques<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>M\u00e9langes de tocoph\u00e9rols<\/strong><\/td>\n              <td>Antioxydant principal de la phase lipidique<\/td>\n              <td>Composant antioxydant couramment utilis\u00e9 dans les syst\u00e8mes huileux<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Squalane<\/strong><\/td>\n              <td>Huile de support \u00e9molliente et stable<\/td>\n              <td>Huile de base hautement stable \u00e0 l'oxydation avec une excellente compatibilit\u00e9 cutan\u00e9e<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Huile d'argousier<\/strong> (dilu\u00e9e)<\/td>\n              <td>Huile botanique riche en lipides avec des composants antioxydants<\/td>\n              <td>G\u00e9n\u00e9ralement utilis\u00e9e \u00e0 faibles doses en raison de sa couleur et de son odeur fortes<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>Ce qu'il faut \u00e9viter dans le blanchiment en phase huileuse :<\/strong><\/p>\n      <ul>\n        <li>Acide L-ascorbique brut \u2014 non liposoluble ; incompatibilit\u00e9 de pH ; fonctionnalit\u00e9 limit\u00e9e dans les syst\u00e8mes anhydres<\/li>\n        <li>Huiles de support sujettes \u00e0 l'oxydation (par exemple, \u00e9glantier non dilu\u00e9, onagre) \u2014 teneur \u00e9lev\u00e9e en AGV augmente le risque d'oxydation et peut augmenter la demande sur les syst\u00e8mes antioxydants<\/li>\n      <\/ul>\n\n      <h3>S\u00e9lection de la base d'huile<\/h3>\n\n      <p>Le syst\u00e8me d'huile de base influence \u00e0 la fois le profil sensoriel et la stabilit\u00e9 des ingr\u00e9dients actifs.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Type d'huile<\/th>\n              <th>Stabilit\u00e9 \u00e0 l&#039;oxydation<\/th>\n              <th>Notes<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Squalane<\/td>\n              <td>Hautement stable<\/td>\n              <td>L'un des \u00e9mollients les plus stables \u00e0 l'oxydation ; tr\u00e8s faible tendance \u00e0 la formation de peroxyde ; huile de support id\u00e9ale<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de cam\u00e9lia (Tsubaki)<\/td>\n              <td>Stable<\/td>\n              <td>Teneur \u00e9lev\u00e9e en acide ol\u00e9ique ; stabilit\u00e9 oxydative relativement bonne ; profil sensoriel agr\u00e9able<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de jojoba (cire liquide)<\/td>\n              <td>Hautement stable<\/td>\n              <td>La structure d'ester de cire contribue \u00e0 une excellente stabilit\u00e9 oxydative ; profil non com\u00e9dog\u00e8ne<\/td>\n            <\/tr>\n            <tr>\n              <td>MCT (noix de coco fractionn\u00e9e)<\/td>\n              <td>Hautement stable<\/td>\n              <td>Triglyc\u00e9rides \u00e0 cha\u00eene moyenne satur\u00e9s ; texture l\u00e9g\u00e8re et bonne stabilit\u00e9<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de rose musqu\u00e9e<\/td>\n              <td>Mod\u00e9r\u00e9ment stable<\/td>\n              <td>Teneur \u00e9lev\u00e9e en acide linol\u00e9ique et linol\u00e9nique ; n\u00e9cessite un soutien du syst\u00e8me antioxydant<\/td>\n            <\/tr>\n            <tr>\n              <td>Argousier (dilu\u00e9)<\/td>\n              <td>Faible \u00e0 mod\u00e9r\u00e9<\/td>\n              <td>Diluer \u00e0 1\u20135 % ; couleur forte et sensibilit\u00e9 \u00e0 l'oxydation<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>Pour les huiles pour le visage \u00e9claircissantes, l'approche de base recommand\u00e9e : <strong>squalane ou jojoba comme support principal (50\u201370 %)<\/strong>, avec des huiles fonctionnelles (cam\u00e9lia, rose musqu\u00e9e, argousier) \u00e0 des concentrations plus faibles pour des co-b\u00e9n\u00e9fices sp\u00e9cifiques.<\/p>\n\n      <h2>Mod\u00e8les de formulation<\/h2>\n\n      <h3>Mod\u00e8le 1 \u2014 Huile \u00c9claircissante pour le Visage (Standard)<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Ingr\u00e9dient<\/th>\n              <th>Plage de %<\/th>\n              <th>Fonction<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Squalane<\/td>\n              <td>40\u201360 %<\/td>\n              <td>Support principal ; tr\u00e8s stable \u00e0 l'oxydation<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de jojoba<\/td>\n              <td>15\u201325 %<\/td>\n              <td>Ester de cire ; stable ; non com\u00e9dog\u00e8ne<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de cam\u00e9lia<\/td>\n              <td>10\u201320 %<\/td>\n              <td>\u00c9mollient ; support riche en acide ol\u00e9ique<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Glabridine 90 % liposoluble<\/strong><\/td>\n              <td><strong>~0,2 %<\/strong><\/td>\n              <td>Actif \u00e9claircissant principal<\/td>\n            <\/tr>\n            <tr>\n              <td>Bakuchiol<\/td>\n              <td>0,5\u20131,0 %<\/td>\n              <td>Soutien du conditionnement de la peau \/ anti-\u00e2ge<\/td>\n            <\/tr>\n            <tr>\n              <td>Ascorbate de Tetrahexyld\u00e9cyle (THDC)<\/td>\n              <td>2\u20135 %<\/td>\n              <td>Vitamine C liposoluble ; soutien \u00e9claircissant \/ soutien antioxydant<\/td>\n            <\/tr>\n            <tr>\n              <td>Tocoph\u00e9rols mixtes<\/td>\n              <td>0,3\u20130,5 %<\/td>\n              <td>Antioxydant principal (fortement recommand\u00e9)<\/td>\n            <\/tr>\n            <tr>\n              <td>Extrait de romarin<\/td>\n              <td>0,05\u20130,2%<\/td>\n              <td>Antioxydant naturel secondaire (compatible COSMOS)<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>Conditionnement:<\/strong> Flacon compte-gouttes opaque ou pompe sans air. Verre ambr\u00e9 ou fonc\u00e9 acceptable si un joint int\u00e9rieur en aluminium est inclus.<\/p>\n\n      <h3>Mod\u00e8le 2 \u2014 Huile \u00c9claircissante pour les L\u00e8vres<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Ingr\u00e9dient<\/th>\n              <th>Plage de %<\/th>\n              <th>Fonction<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Huile de jojoba<\/td>\n              <td>30\u201350 %<\/td>\n              <td>Stable ; non com\u00e9dog\u00e8ne ; confortable sur les l\u00e8vres<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de ricin<\/td>\n              <td>20\u201330 %<\/td>\n              <td>Viscosit\u00e9 ; brillance ; adh\u00e9rence<\/td>\n            <\/tr>\n            <tr>\n              <td>Squalane<\/td>\n              <td>10\u201320 %<\/td>\n              <td>\u00c9mollient stable<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Glabridine 90 % liposoluble<\/strong><\/td>\n              <td><strong>0,1\u20130,2 %<\/strong><\/td>\n              <td>Activit\u00e9 \u00e9claircissante et anti-inflammatoire<\/td>\n            <\/tr>\n            <tr>\n              <td>T\u00e9trahexyld\u00e9cyl Ascorbate \/ Ascorbyl Palmitate<\/td>\n              <td>1\u20133 %<\/td>\n              <td>Vitamine C liposoluble ; soutien antioxydant \/ \u00e9claircissant<\/td>\n            <\/tr>\n            <tr>\n              <td>Tocoph\u00e9rols mixtes<\/td>\n              <td>0,3\u20130,5 %<\/td>\n              <td>Antioxydant principal (fortement recommand\u00e9)<\/td>\n            <\/tr>\n            <tr>\n              <td>Ar\u00f4me (si utilis\u00e9)<\/td>\n              <td>Conform\u00e9ment \u00e0 la limite r\u00e9glementaire<\/td>\n              <td>Sans parfum de pr\u00e9f\u00e9rence pour un positionnement sensible<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout warning\">\n        <p><strong>Note r\u00e9glementaire :<\/strong> Confirmer la conformit\u00e9 r\u00e9gionale pour l'utilisation dans les produits \u00e0 l\u00e8vres (y compris les consid\u00e9rations d'ingestion accidentelle) avant la commercialisation des formulations contenant de la glabridine.<\/p>\n      <\/div>\n\n      <h3>Mod\u00e8le 3 \u2014 Baume \u00c9claircissant Anhydre (Haute Performance)<\/h3>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Ingr\u00e9dient<\/th>\n              <th>Plage de %<\/th>\n              <th>Fonction<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Squalane<\/td>\n              <td>30\u201345 %<\/td>\n              <td>Support stable<\/td>\n            <\/tr>\n            <tr>\n              <td>Cire d'abeille ou cire v\u00e9g\u00e9tale<\/td>\n              <td>10\u201320 %<\/td>\n              <td>Structure ; texture semi-solide<\/td>\n            <\/tr>\n            <tr>\n              <td>Beurre de karit\u00e9 (raffin\u00e9)<\/td>\n              <td>15\u201325 %<\/td>\n              <td>\u00c9mollient ; occlusif ; beurre riche en lipides<\/td>\n            <\/tr>\n            <tr>\n              <td>Huile de jojoba<\/td>\n              <td>10\u201315 %<\/td>\n              <td>Ester de cire ; stable<\/td>\n            <\/tr>\n            <tr>\n              <td><strong>Glabridine 90 % liposoluble<\/strong><\/td>\n              <td><strong>~0,2 %<\/strong><\/td>\n              <td>Actif \u00e9claircissant principal<\/td>\n            <\/tr>\n            <tr>\n              <td>Bakuchiol<\/td>\n              <td>0,5\u20131,0 %<\/td>\n              <td>Soutien du conditionnement de la peau \/ anti-\u00e2ge<\/td>\n            <\/tr>\n            <tr>\n              <td>Tocoph\u00e9rols mixtes<\/td>\n              <td>0,5%<\/td>\n              <td>Antioxydant (niveau plus \u00e9lev\u00e9 recommand\u00e9 pour les syst\u00e8mes de baume en raison de la structure semi-solide)<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <h2>Protocole de Stabilit\u00e9 pour les Syst\u00e8mes \u00e0 Base d'Huile<\/h2>\n\n      <p>Les syst\u00e8mes \u00e0 base d'huile n\u00e9cessitent un protocole de stabilit\u00e9 adapt\u00e9 \u00e0 leurs risques de d\u00e9gradation sp\u00e9cifiques.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr>\n              <th>Test<\/th>\n              <th>Condition<\/th>\n              <th>Dur\u00e9e<\/th>\n              <th>R\u00e9f\u00e9rence R\u00e9glementaire<\/th>\n            <\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Acc\u00e9l\u00e9r\u00e9 (haute temp\u00e9rature)<\/td>\n              <td>40\u00b0C \/ humidit\u00e9 ambiante<\/td>\n              <td>12 semaines<\/td>\n              <td>ICH Q1A(R2)<\/td>\n            <\/tr>\n            <tr>\n              <td>Cong\u00e9lation-d\u00e9gel<\/td>\n              <td>\u221210\u00b0C \u2194 25\u00b0C, cycles de 24h<\/td>\n              <td>5 cycles<\/td>\n              <td>Ligne directrice PCPC\/CTFA<\/td>\n            <\/tr>\n            <tr>\n              <td>Photostabilit\u00e9<\/td>\n              <td>D65 + UV selon ICH Q1B<\/td>\n              <td>6 semaines<\/td>\n              <td>ICH Q1B<\/td>\n            <\/tr>\n            <tr>\n              <td>Ranceur (sp\u00e9cifique \u00e0 l'huile)<\/td>\n              <td>Indice de peroxyde (IP) et indice p-anisidine (IA)<\/td>\n              <td>\u00c0 chaque point temporel<\/td>\n              <td>M\u00e9thodes AOCS<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>Param\u00e8tres d'\u00e9valuation sp\u00e9cifiques aux syst\u00e8mes \u00e0 base d'huile :<\/strong><\/p>\n      <ul>\n        <li>Dosage de la glabridine par HPLC (int\u00e9grit\u00e9 de l'actif)<\/li>\n        <li>Indice de peroxyde (IP) \u2014 produits d'oxydation primaires dans la base d'huile<\/li>\n        <li>Couleur : CIE L*a*b* \u2014 suivi de \u0394b* (indice de jaunissement)<\/li>\n        <li>Organoleptique : odeur de ranceur, s\u00e9dimentation visuelle<\/li>\n        <li>\u00c9valuation de la s\u00e9dimentation : v\u00e9rification visuelle \u00e0 chaque point temporel sous \u00e9clairage standardis\u00e9<\/li>\n      <\/ul>\n\n      <p>Le param\u00e8tre de ranceur est sp\u00e9cifique aux syst\u00e8mes \u00e0 base d'huile et n'est g\u00e9n\u00e9ralement pas inclus dans les protocoles d'\u00e9mulsion. L'oxydation de l'huile peut g\u00e9n\u00e9rer des odeurs d\u00e9sagr\u00e9ables et des produits peroxyd\u00e9s qui peuvent affecter \u00e0 la fois les propri\u00e9t\u00e9s sensorielles et la qualit\u00e9 globale du produit.<\/p>\n\n      <div class=\"callout\">\n        <p>Chaque lot est exp\u00e9di\u00e9 avec COA, TDS et SDS\/MSDS. Tests suppl\u00e9mentaires disponibles sur demande.<\/p>\n      <\/div>\n\n      <!-- Related -->\n      <div class=\"related-section\">\n        <h2>Ressources connexes<\/h2>\n        <div class=\"related-links\">\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/glabridin\/\">\n            <span>Guide de la Glabridine pour la Formulation Cosm\u00e9tique \u2014 R\u00e9f\u00e9rence Technique Compl\u00e8te<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Matrice de qualit\u00e9 compl\u00e8te, donn\u00e9es de qualit\u00e9 liposoluble et protocoles de stabilit\u00e9<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/what-is-the-difference-between-glabridin-grades\/\">\n            <span>Quelle est la diff\u00e9rence entre les grades de glabridine ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">S\u00e9lection de la qualit\u00e9 liposoluble par rapport \u00e0 la qualit\u00e9 hydrosoluble ou alcool-soluble<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/can-glabridin-be-combined-with-retinol\/\">\n            <span>Le Glabridin peut-il \u00eatre combin\u00e9 avec le r\u00e9tinol ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Bakuchiol comme alternative compatible au r\u00e9tinol dans les syst\u00e8mes \u00e0 base d'huile<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/how-to-stabilize-glabridin-in-cosmetic-formulations\/\">\n            <span>Comment stabiliser la glabridine dans les formulations cosm\u00e9tiques ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Protocole de stabilisation complet incluant les consid\u00e9rations de la phase huileuse<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n        <\/div>\n      <\/div>\n\n      <!-- CTA -->\n      <div class=\"cta-box\">\n        <div class=\"cta-box-text\">\n          <strong>Demander des \u00e9chantillons, un COA ou une consultation technique<\/strong>\n          glabridinchina.com \u00b7 jelly@huataibio.com \u00b7 +86 17868678161\n        <\/div>\n        <a class=\"cta-btn\" href=\"https:\/\/glabridinchina.com\/fr\/nous-contacter\/\">Contactez-nous \u2192<\/a>\n      <\/div>\n\n      <!-- References -->\n      <div class=\"references\">\n        <h2>R\u00e9f\u00e9rences<\/h2>\n        <ol>\n          <li>Yokota T, Nishio H, Kubota Y, Mizoguchi M. L'effet inhibiteur de la glabridine extraite de la r\u00e9glisse sur la m\u00e9lanogen\u00e8se et l'inflammation. <em>Pigment Cell Research<\/em>, 11(6), 355\u2013361, 1998. DOI: 10.1111\/j.1600-0749.1998.tb00494.x.<\/li>\n          <li>Ao M, Shi Y, Cui Y, Guo W, Wang J, Yu L. Facteurs influen\u00e7ant la stabilit\u00e9 de la glabridine. <em>Natural Product Communications<\/em>, Vol. 5(12), 1907\u20131912, 2010. DOI: 10.1177\/1934578X1000501214. PMID: 21299118.<\/li>\n          <li>ICH Q1A(R2) : Essais de stabilit\u00e9 des nouvelles substances m\u00e9dicamenteuses et des nouveaux produits m\u00e9dicamenteux. Conseil international d'harmonisation, 2003.<\/li>\n          <li>ICH Q1B : Essais de photostabilit\u00e9 des nouvelles substances et des nouveaux produits m\u00e9dicamenteux. Conseil international d'harmonisation, 1996.<\/li>\n        <\/ol>\n      <\/div>\n\n      <div class=\"article-footer\">\n        <p>Pour les formulateurs de cosm\u00e9tiques professionnels et les publics de R&amp;D. Ne constitue pas un avis r\u00e9glementaire.<br>\n        Publi\u00e9 en 2026 \u2014 Huatai Bio-Fine Chemical, Xi'an, Shaanxi, Chine.<\/p>\n      <\/div>\n\n    <\/article>\n  <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>Application Huile de glabridine Syst\u00e8mes anhydres et \u00e0 base d'huile Les syst\u00e8mes \u00e0 base d'huile et anhydres offrent un environnement de formulation favorable \u00e0 la glabridine. L'absence d'eau r\u00e9duit les principaux risques de stabilit\u00e9, et\u2026<\/p>","protected":false},"author":8,"featured_media":5798,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[411],"tags":[],"class_list":["post-14283","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-application-guides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Oil-Soluble Brightening Systems: Formulating High-Performance Anhydrous Glow Products | Huatai Bio-Fine Chemical<\/title>\n<meta name=\"description\" content=\"A technical guide to formulating oil-based and anhydrous brightening products using the 90% oil-soluble glabridin grade \u2014 covering face oils, lip oils, oil serums, and anhydrous balms, with stability data, active system design, and formulation blueprints. 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