{"id":14137,"date":"2026-06-11T02:23:01","date_gmt":"2026-06-11T02:23:01","guid":{"rendered":"https:\/\/glabridinchina.com\/?p=14137"},"modified":"2026-06-11T02:43:23","modified_gmt":"2026-06-11T02:43:23","slug":"can-glabridin-work-in-water-based-systems","status":"publish","type":"post","link":"https:\/\/glabridinchina.com\/fr\/can-glabridin-work-in-water-based-systems\/","title":{"rendered":"La glabridine peut-elle fonctionner dans des syst\u00e8mes \u00e0 base d'eau ?"},"content":{"rendered":"<div data-elementor-type=\"wp-post\" data-elementor-id=\"14137\" class=\"elementor elementor-14137\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-bbfdf4f e-flex e-con-boxed e-con e-parent\" data-id=\"bbfdf4f\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-41feb3c elementor-widget elementor-widget-html\" data-id=\"41feb3c\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<script type=\"application\/ld+json\">{\n    \"@context\": \"https:\\\/\\\/schema.org\",\n    \"@type\": \"FAQPage\",\n    \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\\\/\\\/glabridinchina.com\\\/can-glabridin-work-in-water-based-systems\\\/\"\n    },\n    \"about\": {\n        \"@type\": \"ChemicalSubstance\",\n        \"name\": \"Glabridin\",\n        \"alternateName\": \"\\u5149\\u7518\\u8349\\u5b9a\"\n    },\n    \"publisher\": {\n        \"@type\": \"Organization\",\n        \"name\": \"Huatai Bio-Fine Chemical\",\n        \"url\": \"https:\\\/\\\/glabridinchina.com\"\n    },\n    \"mainEntity\": [\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Can glabridin be used in water-based cosmetic systems?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Yes. Glabridin can be incorporated into water-based systems using two purpose-built grades: the 10% water-soluble powder (hydroxypropyl \\u03b2-cyclodextrin encapsulated, loading capacity 15\\u201318% stably maintained at 10%) and the 1\\u20135% water-soluble liquid grades. Both can be incorporated directly into the aqueous phase. The 10% water-soluble powder is the preferred choice for most aqueous formats \\u2014 it is COSMOS-certified, shows improved photostability compared to unencapsulated glabridin in aqueous systems, and is compatible with toners, essences, hydrogels, and water-based serums.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What technology enables glabridin to disperse in water?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Huatai's 10% water-soluble grade uses hydroxypropyl \\u03b2-cyclodextrin (HP-\\u03b2-CD) inclusion complex technology. HP-\\u03b2-CD has a hydrophilic outer surface and a hydrophobic inner cavity. Glabridin \\u2014 which is inherently lipophilic \\u2014 is encapsulated within the cavity, while the hydrophilic outer surface enables aqueous dispersion. The loading capacity is 15\\u201318%, stably maintained at 10% active content. HP-\\u03b2-CD encapsulation also supports potential improved delivery and may contribute to a more gradual release profile compared to free glabridin.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"How does HP-\\u03b2-CD encapsulation affect glabridin stability in water?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"HP-\\u03b2-CD encapsulation improves glabridin's photostability in aqueous systems compared to unencapsulated glabridin. Internal stability testing shows the HP-\\u03b2-CD inclusion complex retains approximately 90% of its mass after 4 days of light exposure (Huatai internal stability data). Thermal stability is maintained at approximately 100\\u00b0C processing conditions, making it compatible with standard cosmetic manufacturing temperatures.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"What is the difference between the 10% water-soluble powder and the 1\\u20135% water-soluble liquid grade?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"The 10% water-soluble powder uses HP-\\u03b2-CD encapsulation technology and is a dry powder that disperses directly in water. It has a 24-month shelf life. The 1\\u20135% liquid grades are pre-dissolved solutions that also incorporate directly in water but contain approved preservatives \\u2014 these should be considered in the overall preservative system of the finished formulation. The liquid grades have a 12-month shelf life. For most water-based applications, the 10% powder is preferred for its higher active concentration, longer shelf life, and absence of added preservatives.\"\n            }\n        },\n        {\n            \"@type\": \"Question\",\n            \"name\": \"Can the water-soluble glabridin grade be used in toners and essences?\",\n            \"acceptedAnswer\": {\n                \"@type\": \"Answer\",\n                \"text\": \"Yes. The 10% water-soluble powder and 1\\u20135% water-soluble liquid grades are both suitable for toners, essences, hydrogels, and water-based serums. Add directly to the water phase or during cool-down. Additional co-solvents are typically not required for the 10% powder grade. For the liquid grades, the included preservatives should be considered in your regulatory documentation and overall preservative system.\"\n            }\n        }\n    ]\n}<\/script>\n\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n  <link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin>\n  <link href=\"https:\/\/fonts.googleapis.com\/css2?family=Inter:wght@300;400;500;600;700&family=Merriweather:ital,wght@0,400;0,700;1,400&display=swap\" rel=\"stylesheet\">\n\n  <style>\n    :root {\n      --color-bg:           #f9f9f7;\n      --color-surface:      #ffffff;\n      --color-border:       #e5e2d9;\n      --color-text:         #1c1c1a;\n      --color-text-muted:   #6a6760;\n      --color-accent:       #2d5a3d;\n      --color-accent-light: #edf4ef;\n      --color-accent-mid:   #4a7c5f;\n      --color-warn:         #7a4f1e;\n      --color-warn-light:   #fdf4eb;\n      --color-data-bg:      #f3f1ed;\n      --font-heading:       'Merriweather', Georgia, 'Times New Roman', serif;\n      --font-body:          'Inter', -apple-system, BlinkMacSystemFont, 'Segoe UI', Helvetica, Arial, sans-serif;\n      --max-width:          800px;\n      --radius:             6px;\n    }\n\n    *, *::before, *::after { box-sizing: border-box; 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La glabridine peut \u00eatre incorpor\u00e9e dans des syst\u00e8mes \u00e0 base d'eau en utilisant des grades sp\u00e9cialement con\u00e7us qui permettent la dispersion dans les milieux aqueux. Cet article couvre la technologie d'encapsulation HP-\u03b2-CD, les deux options de grades compatibles avec l'eau, les consid\u00e9rations de stabilit\u00e9 et les directives d'incorporation pour les formats courants \u00e0 base d'eau.<\/p>\n      <div class=\"byline\">\n        <span><strong>Huatai Bio-Fine Chemical<\/strong> \u2014 fabricant d'actifs cosm\u00e9tiques de haute puret\u00e9 depuis 2008<\/span>\n        <span style=\"color:var(--color-border)\">\u00b7<\/span>\n        <span>Publi\u00e9 2026<\/span>\n      <\/div>\n    <\/header>\n\n    <article class=\"article-body\">\n\n      <p>Oui. La glabridine peut \u00eatre incorpor\u00e9e dans des syst\u00e8mes \u00e0 base d'eau en utilisant des grades sp\u00e9cialement con\u00e7us qui permettent la dispersion dans les milieux aqueux. La glabridine standard est intrins\u00e8quement lipophile \u2014 elle ne se dissout pas dans l'eau. Huatai a d\u00e9velopp\u00e9 deux familles de grades compatibles avec l'eau qui permettent l'incorporation dans les syst\u00e8mes aqueux gr\u00e2ce \u00e0 des technologies de formulation sp\u00e9cialis\u00e9es tout en soutenant la stabilit\u00e9 de l'actif dans des conditions de formulation appropri\u00e9es.<\/p>\n\n      <h2>Le d\u00e9fi de la solubilit\u00e9 et sa solution<\/h2>\n\n      <p>La structure isoflavane de la glabridine est intrins\u00e8quement lipophile et pr\u00e9sente une solubilit\u00e9 dans l'eau tr\u00e8s limit\u00e9e. Dans les syst\u00e8mes \u00e0 base d'eau, la glabridine non modifi\u00e9e peut \u00eatre difficile \u00e0 disperser uniform\u00e9ment et peut pr\u00e9senter des d\u00e9fis de formulation tels que la s\u00e9dimentation ou une distribution non uniforme de l'actif si elle n'est pas correctement solubilis\u00e9e ou stabilis\u00e9e.<\/p>\n\n      <p>Une approche traditionnelle consiste \u00e0 utiliser des co-solvants tels que le propyl\u00e8ne glycol ou l'\u00e9thanol pour am\u00e9liorer la solubilit\u00e9. Cependant, les niveaux de solvant requis peuvent \u00eatre moins souhaitables pour les toniques pour peaux sensibles, les essences ou les formulations de gels hydratants o\u00f9 la douceur et le confort cutan\u00e9 sont des consid\u00e9rations de formulation importantes.<\/p>\n\n      <p>La solution consiste \u00e0 s\u00e9lectionner un grade sp\u00e9cialement con\u00e7u pour les syst\u00e8mes \u00e0 base d'eau.<\/p>\n\n      <h2>Les deux options de grades compatibles avec l'eau<\/h2>\n\n      <h3>Option 1 \u2014 Poudre soluble dans l'eau 10% (encapsul\u00e9e HP-\u03b2-CD)<\/h3>\n\n      <p>C'est le grade principal recommand\u00e9 pour les applications \u00e0 base d'eau.<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr><th>Param\u00e8tre<\/th><th>D\u00e9tail<\/th><\/tr>\n          <\/thead>\n          <tbody>\n            <tr><td>Forme physique<\/td><td>Poudre blanche<\/td><\/tr>\n            <tr><td>Dispersibilit\u00e9 aqueuse<\/td><td>Facilement dispersible dans les syst\u00e8mes \u00e0 base d'eau<\/td><\/tr>\n            <tr><td>Teneur en actif<\/td><td>Glabridine 10%<\/td><\/tr>\n            <tr><td>Technologie d'encapsulation<\/td><td>Complexe d'inclusion d'hydroxypropyl \u03b2-cyclodextrine (HP-\u03b2-CD)<\/td><\/tr>\n            <tr><td>Capacit\u00e9 de chargement<\/td><td>15\u201318% (maintenu de mani\u00e8re stable \u00e0 10%)<\/td><\/tr>\n            <tr><td>Stabilit\u00e9 thermique<\/td><td>D\u00e9composition lente maintenue \u00e0 ~100\u00b0C<\/td><\/tr>\n            <tr><td>Photostabilit\u00e9<\/td><td>Perte de masse de ~1% sur 4 jours d'exposition \u00e0 la lumi\u00e8re (donn\u00e9es internes Huatai)<\/td><\/tr>\n            <tr><td>dur\u00e9e de conservation<\/td><td>24 mois<\/td><\/tr>\n            <tr><td>Statut COSMOS<\/td><td>Agr\u00e9\u00e9<\/td><\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p><strong>Comment \u00e7a marche :<\/strong> Le HP-\u03b2-CD poss\u00e8de une surface ext\u00e9rieure hydrophile et une cavit\u00e9 int\u00e9rieure hydrophobe. La glabridine est encapsul\u00e9e dans la cavit\u00e9 hydrophobe du HP-\u03b2-CD pour former un complexe d'inclusion. Lorsqu'il est dispers\u00e9 dans l'eau, l'ensemble du complexe devient dispersible dans l'eau, permettant la formation d'une dispersion aqueuse stable. Le syst\u00e8me r\u00e9sultant peut appara\u00eetre comme une dispersion claire \u00e0 l\u00e9g\u00e8rement opalescente en fonction de la concentration et des conditions de formulation.<\/p>\n\n      <p>Au-del\u00e0 de la dispersibilit\u00e9 dans l'eau, l'encapsulation par HP-\u03b2-CD offre deux avantages de performance potentiels suppl\u00e9mentaires :<\/p>\n      <ul>\n        <li><strong>Am\u00e9lioration potentielle de la d\u00e9livrance :<\/strong> Le HP-\u03b2-CD peut am\u00e9liorer la d\u00e9livrance des actifs encapsul\u00e9s en am\u00e9liorant leur dispersibilit\u00e9 dans l'eau et leur solubilit\u00e9 apparente.<\/li>\n        <li><strong>Comportement potentiel de lib\u00e9ration contr\u00f4l\u00e9e :<\/strong> L'inclusion de HP-\u03b2-CD peut contribuer \u00e0 un profil de lib\u00e9ration plus graduel par rapport \u00e0 la glabridine libre.<\/li>\n      <\/ul>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_hpbcd_permeation.png\"\n             alt=\"Graphique lin\u00e9aire montrant la quantit\u00e9 cumul\u00e9e de perm\u00e9ation de GLA vs GLA-HP-\u03b2-CD sur 12 heures, avec GLA-HP-\u03b2-CD montrant une perm\u00e9ation plus \u00e9lev\u00e9e tout au long\">\n        <figcaption>Fig. 1 \u2014 Profil de la quantit\u00e9 de perm\u00e9ation cumulative de la glabridine (GLA) et du complexe d'inclusion de glabridine HP\u2013\u03b2\u2013CD. Le GLA\u2013HP\u2013\u03b2\u2013CD montre une perm\u00e9ation cumulative plus \u00e9lev\u00e9e \u00e0 tous les points temporels. Donn\u00e9es : donn\u00e9es internes Huatai.<\/figcaption>\n      <\/figure>\n\n      <h3>Option 2 \u2014 1\u20135% Grades Liquides Solubles dans l'Eau<\/h3>\n\n      <p>Concentr\u00e9s liquides pr\u00e9dissous disponibles en deux variantes :<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr><th>Variante<\/th><th>Couleur<\/th><th>Preservative<\/th><\/tr>\n          <\/thead>\n          <tbody>\n            <tr><td>liquide incolore \u00e0 jaune p\u00e2le<\/td><td>Incolore<\/td><td>Contient un conservateur approuv\u00e9<\/td><\/tr>\n            <tr><td>Liquide brun rouge\u00e2tre \u00e0 brun fonc\u00e9<\/td><td>Brun<\/td><td>Contient un conservateur approuv\u00e9<\/td><\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <p>Les deux variantes sont des syst\u00e8mes pr\u00e9-solubilis\u00e9s compatibles avec l'eau et peuvent \u00eatre ajout\u00e9s directement \u00e0 la phase aqueuse. La principale consid\u00e9ration de formulation : <strong>ces grades contiennent des conservateurs approuv\u00e9s<\/strong>. Le conservateur inclus doit \u00eatre pris en compte dans le syst\u00e8me de conservation global de la formulation finie et d\u00e9clar\u00e9 dans la documentation r\u00e9glementaire.<\/p>\n\n      <p>Les grades liquides 1\u20135% conviennent bien aux formulations o\u00f9 un concentr\u00e9 pr\u00e9dissous et pr\u00eat \u00e0 l'emploi est pr\u00e9f\u00e9r\u00e9 \u2014 particuli\u00e8rement utile pour le m\u00e9lange en petits lots ou pour les marques sans infrastructure de pes\u00e9e de poudre.<\/p>\n\n      <h2>Photostabilit\u00e9 dans l'eau : l'avantage de l'encapsulation<\/h2>\n\n      <p>Dans les syst\u00e8mes aqueux, la glabridine non encapsul\u00e9e peut \u00eatre plus susceptible \u00e0 la photod\u00e9gradation. Dans l'eau, l'environnement polaire peut augmenter la susceptibilit\u00e9 des groupes hydroxyles ph\u00e9noliques \u00e0 la d\u00e9gradation oxydative, et l'absence d'antioxydants de phase lipidique (tels que le tocoph\u00e9rol lorsqu'il est pr\u00e9sent) peut r\u00e9duire la protection antioxydante.<\/p>\n\n      <p>L'encapsulation par HP-\u03b2-CD peut aider \u00e0 r\u00e9soudre ce probl\u00e8me. Les tests de stabilit\u00e9 interne du complexe d'inclusion HP-\u03b2-CD montrent :<\/p>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr><th>Condition<\/th><th>Complexe HP-\u03b2-CD Glabridine<\/th><th>Source<\/th><\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Exposition \u00e0 la lumi\u00e8re, 4 jours<\/td>\n              <td>Perte de masse ~10%<\/td>\n              <td>Donn\u00e9es de stabilit\u00e9 interne Huatai<\/td>\n            <\/tr>\n            <tr>\n              <td>Thermique (~100\u00b0C de traitement)<\/td>\n              <td>D\u00e9composition lente<\/td>\n              <td>Donn\u00e9es de stabilit\u00e9 interne Huatai<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <figure class=\"figure\">\n        <img decoding=\"async\" src=\"https:\/\/glabridinchina.com\/wp-content\/uploads\/2026\/06\/glabridin_hpbcd_photostability.png\"\n             alt=\"Graphique lin\u00e9aire montrant le taux de d\u00e9composition du complexe d&#039;inclusion de glabridine HP-\u03b2-CD sur 4 jours d&#039;exposition \u00e0 la lumi\u00e8re, atteignant environ 10-11% aux jours 3-4\">\n        <figcaption>Fig. 2 \u2014 Photostabilit\u00e9 du complexe d'inclusion glabridine HP\u2013\u03b2\u2013CD. Le taux de d\u00e9composition reste inf\u00e9rieur \u00e0 11% apr\u00e8s 4 jours d'exposition \u00e0 la lumi\u00e8re. Donn\u00e9es : Donn\u00e9es de stabilit\u00e9 interne Huatai.<\/figcaption>\n      <\/figure>\n\n      <p>La cavit\u00e9 de la cyclodextrine peut encapsuler la mol\u00e9cule de glabridine, r\u00e9duisant son exposition \u00e0 la lumi\u00e8re et \u00e0 l'environnement aqueux environnant, ce qui peut aider \u00e0 am\u00e9liorer la stabilit\u00e9 par rapport \u00e0 la forme non encapsul\u00e9e.<\/p>\n\n      <p>Pour l'emballage du produit fini, les m\u00eames r\u00e8gles s'appliquent quel que soit le grade : un emballage protecteur contre les UV ou opaque est particuli\u00e8rement important pour les formats clairs \u00e0 base d'eau (par exemple, les toniques et les essences) afin de minimiser la d\u00e9gradation induite par la lumi\u00e8re pendant le stockage et l'utilisation.<\/p>\n\n      <h2>Lignes directrices d'incorporation pour les syst\u00e8mes \u00e0 base d'eau<\/h2>\n\n      <h3>Poudre hydrosoluble 10%<\/h3>\n      <ol>\n        <li>Ajouter directement \u00e0 la phase aqueuse \u00e0 temp\u00e9rature ambiante jusqu'\u00e0 40\u00b0C ; remuer jusqu'\u00e0 dispersion compl\u00e8te.<\/li>\n        <li>Aucun solubilisant suppl\u00e9mentaire n'est g\u00e9n\u00e9ralement requis.<\/li>\n        <li>Niveau d'utilisation cible : ajuster en fonction du syst\u00e8me de formulation et du niveau d'actif cible \u2014 le grade 10% offre une flexibilit\u00e9 pour une gamme de concentrations d'actifs.<\/li>\n        <li>V\u00e9rifier le pH final une fois tous les ajouts de refroidissement termin\u00e9s ; pH cible 4,0\u20135,5.<\/li>\n      <\/ol>\n\n      <h3>Grades liquides hydrosolubles 1\u20135%<\/h3>\n      <ol>\n        <li>Ajouter directement \u00e0 la phase aqueuse ou pendant le refroidissement.<\/li>\n        <li>Le conservateur inclus doit \u00eatre pris en compte dans le syst\u00e8me de conservation global.<\/li>\n        <li>Confirmer l'identit\u00e9 et la concentration du conservateur avec le COA du fournisseur avant de finaliser la d\u00e9claration du conservateur.<\/li>\n        <li>V\u00e9rifier le pH final une fois tous les ajouts de refroidissement termin\u00e9s ; pH cible 4,0\u20135,5.<\/li>\n      <\/ol>\n\n      <h3>Renforcement de la stabilit\u00e9 pour les syst\u00e8mes \u00e0 base d'eau<\/h3>\n      <ul>\n        <li>Inclure un ch\u00e9lateur m\u00e9tallique dans la phase aqueuse : EDTA disodique (0,05\u20130,11 TP3T) ou phytate de sodium (0,1\u20130,51 TP3T) pour les syst\u00e8mes compatibles COSMOS.<\/li>\n        <li>Utiliser une phase aqueuse tamponn\u00e9e (acide citrique\/citrate de sodium ou acide lactique\/lactate de sodium) pour maintenir la stabilit\u00e9 du pH pendant la dur\u00e9e de conservation.<\/li>\n        <li>Un emballage protecteur contre les UV ou opaque est particuli\u00e8rement important pour les formats clairs \u00e0 base d'eau (par exemple, toniques et essences) afin de minimiser la d\u00e9gradation induite par la lumi\u00e8re pendant le stockage et l'utilisation.<\/li>\n      <\/ul>\n\n      <h2>Formats aqueux applicables<\/h2>\n\n      <div class=\"table-wrap\">\n        <table>\n          <thead>\n            <tr><th>Format<\/th><th>Grade recommand\u00e9<\/th><th>Notes<\/th><\/tr>\n          <\/thead>\n          <tbody>\n            <tr>\n              <td>Tonique \/ Eau pour le visage<\/td>\n              <td>Poudre hydrosoluble de 10% ou liquide hydrosoluble de 1\u20135%<\/td>\n              <td>Incorporation aqueuse directe ; des co-solvants suppl\u00e9mentaires ne sont g\u00e9n\u00e9ralement pas requis<\/td>\n            <\/tr>\n            <tr>\n              <td>Hydrogel<\/td>\n              <td>Poudre hydrosoluble 10%<\/td>\n              <td>Disperser dans la phase aqueuse avant l'ajout de l'agent g\u00e9lifiant<\/td>\n            <\/tr>\n            <tr>\n              <td>S\u00e9rum \u00e0 base d'eau<\/td>\n              <td>Poudre hydrosoluble 10%<\/td>\n              <td>Forte concentration d'actifs possible ; ajuster le niveau d'utilisation par cible<\/td>\n            <\/tr>\n            <tr>\n              <td>Essence de masque en tissu<\/td>\n              <td>Poudre hydrosoluble de 10% ou liquide hydrosoluble de 1\u20135%<\/td>\n              <td>Convient aux formulations d'essence de masque en tissu aqueux<\/td>\n            <\/tr>\n            <tr>\n              <td>Eau micellaire<\/td>\n              <td>1\u20135% liquide soluble dans l'eau<\/td>\n              <td>Format pr\u00e9dissous adapt\u00e9 aux formulations de nettoyage micellaire aqueuse<\/td>\n            <\/tr>\n          <\/tbody>\n        <\/table>\n      <\/div>\n\n      <div class=\"callout\">\n        <p>Chaque lot est exp\u00e9di\u00e9 avec COA, TDS et SDS\/MSDS. Tests suppl\u00e9mentaires disponibles sur demande.<\/p>\n      <\/div>\n\n      <!-- Related -->\n      <div class=\"related-section\">\n        <h2>Ressources connexes<\/h2>\n        <div class=\"related-links\">\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/glabridin\/\">\n            <span>Guide de la Glabridine pour la Formulation Cosm\u00e9tique \u2014 R\u00e9f\u00e9rence Technique Compl\u00e8te<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Matrice de qualit\u00e9 sup\u00e9rieure, donn\u00e9es sur la technologie HP-\u03b2-CD et protocoles de formulation<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/why-does-glabridin-discolor-in-emulsions-huatai-bio-fine-chemical\/\">\n            <span>Pourquoi la glabridine se d\u00e9colore-t-elle dans les \u00e9mulsions ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Diagnostics de stabilit\u00e9 applicables \u00e0 tous les types de syst\u00e8mes<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/how-to-stabilize-glabridin-in-cosmetic-formulations\/\">\n            <span>Comment stabiliser la glabridine dans les formulations cosm\u00e9tiques ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">Protocole de stabilisation complet incluant les consid\u00e9rations relatives \u00e0 la phase aqueuse<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n          <a class=\"related-link\" href=\"https:\/\/glabridinchina.com\/fr\/what-ph-range-does-glabridin-require-in-cosmetic-formulations\uff1f\/\">\n            <span>Quelle plage de pH la glabridine n\u00e9cessite-t-elle dans les formulations cosm\u00e9tiques ?<br>\n            <small style=\"color:var(--color-text-muted);font-weight:400\">S\u00e9lection de tampons pour les syst\u00e8mes aqueux<\/small><\/span>\n            <span class=\"related-link-arrow\">\u2192<\/span>\n          <\/a>\n        <\/div>\n      <\/div>\n\n      <!-- CTA -->\n      <div class=\"cta-box\">\n        <div class=\"cta-box-text\">\n          <strong>Demander des \u00e9chantillons, un COA ou une consultation technique<\/strong>\n          glabridinchina.com \u00b7 jelly@huataibio.com \u00b7 +86 17868678161\n        <\/div>\n        <a class=\"cta-btn\" href=\"https:\/\/glabridinchina.com\/fr\/nous-contacter\/\">Contactez-nous \u2192<\/a>\n      <\/div>\n\n      <!-- References -->\n      <div class=\"references\">\n        <h2>R\u00e9f\u00e9rences<\/h2>\n        <ol>\n          <li>Ao M, Shi Y, Cui Y, Guo W, Wang J, Yu L. Facteurs influen\u00e7ant la stabilit\u00e9 de la glabridine. <em>Natural Product Communications<\/em>, Vol. 5(12), 1907\u20131912, 2010. DOI: 10.1177\/1934578X1000501214. PMID: 21299118.<\/li>\n          <li>Yokota T, Nishio H, Kubota Y, Mizoguchi M. L'effet inhibiteur de la glabridine extraite de la r\u00e9glisse sur la m\u00e9lanogen\u00e8se et l'inflammation. <em>Pigment Cell Research<\/em>, 11(6), 355\u2013361, 1998. DOI: 10.1111\/j.1600-0749.1998.tb00494.x.<\/li>\n          <li>Huatai Bio-Fine Chemical. Donn\u00e9es de stabilit\u00e9 interne du complexe d'inclusion de glabridine soluble dans l'eau. Brevet d'invention chinois ZL202111026952.7, d\u00e9livr\u00e9 le 28 avril 2023.<\/li>\n        <\/ol>\n      <\/div>\n\n      <div class=\"article-footer\">\n        <p>Pour les formulateurs de cosm\u00e9tiques professionnels et les publics de R&amp;D. Ne constitue pas un avis r\u00e9glementaire.<br>\n        Publi\u00e9 en 2026 \u2014 Huatai Bio-Fine Chemical, Xi'an, Shaanxi, Chine.<\/p>\n      <\/div>\n\n    <\/article>\n  <\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>FAQ Glabridin Syst\u00e8mes \u00e0 base d'eau HP-\u03b2-CD Oui. Le glabridin peut \u00eatre incorpor\u00e9 dans des syst\u00e8mes \u00e0 base d'eau en utilisant des qualit\u00e9s sp\u00e9cialement con\u00e7ues qui permettent la dispersion dans les environnements aqueux. Cet article couvre\u2026<\/p>","protected":false},"author":8,"featured_media":5795,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[414],"tags":[],"class_list":["post-14137","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-troubleshooting-faq"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v23.8 (Yoast SEO v24.2) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Can Glabridin Work in Water-Based Systems? | Huatai Bio-Fine Chemical<\/title>\n<meta name=\"description\" content=\"Glabridin can be incorporated into water-based systems using purpose-built HP-\u03b2-CD encapsulated and pre-dissolved liquid grades. 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